Novel motif:119

name:	motif119_TCAAAANCG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006281	DNA repair	1.152724e-12
GO:0071044	histone mRNA catabolic process	1.162461e-11
GO:0007094	mitotic cell cycle spindle assembly checkpoint	3.474359e-11
GO:0015742	alpha-ketoglutarate transport	3.763384e-11
GO:0071173	spindle assembly checkpoint	5.736781e-11
GO:0071174	mitotic cell cycle spindle checkpoint	6.334597e-11
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1.254375e-10
GO:0031577	spindle checkpoint	1.380892e-10
GO:0006289	nucleotide-excision repair	1.786219e-10
GO:0000296	spermine transport	1.403719e-9
GO:0022402	cell cycle process	4.197584e-9
GO:0046940	nucleoside monophosphate phosphorylation	4.198050e-9
GO:0030071	regulation of mitotic metaphase/anaphase transition	5.407658e-9
GO:0090399	replicative senescence	5.746870e-9
GO:0006259	DNA metabolic process	8.231544e-9
GO:0010754	negative regulation of cGMP-mediated signaling	8.419814e-9
GO:0043652	engulfment of apoptotic cell	8.419814e-9
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	8.419814e-9
GO:0010751	negative regulation of nitric oxide mediated signal transduction	8.419814e-9
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	8.419814e-9
GO:0000278	mitotic cell cycle	1.254074e-8
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	1.464073e-8
GO:0010994	free ubiquitin chain polymerization	1.965093e-8
GO:0060574	intestinal epithelial cell maturation	1.965093e-8
GO:0022403	cell cycle phase	3.464126e-8
GO:0006303	double-strand break repair via nonhomologous end joining	3.698434e-8
GO:0051329	interphase of mitotic cell cycle	3.763519e-8
GO:0045839	negative regulation of mitosis	4.069695e-8
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	6.004789e-8
GO:0051325	interphase	6.506433e-8
GO:0032026	response to magnesium ion	8.199417e-8
GO:0040040	thermosensory behavior	8.324543e-8
GO:0032369	negative regulation of lipid transport	1.232340e-7
GO:0000075	cell cycle checkpoint	1.370747e-7
GO:0060764	cell-cell signaling involved in mammary gland development	1.635937e-7
GO:0006975	DNA damage induced protein phosphorylation	1.676504e-7
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	2.705898e-7
GO:0032891	negative regulation of organic acid transport	2.861661e-7
GO:0051897	positive regulation of protein kinase B signaling cascade	3.357321e-7
GO:0010755	regulation of plasminogen activation	3.402193e-7
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	3.846437e-7
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	3.846437e-7
GO:0032074	negative regulation of nuclease activity	3.999737e-7
GO:0019087	transformation of host cell by virus	4.425740e-7
GO:0002331	pre-B cell allelic exclusion	4.737477e-7
GO:0045786	negative regulation of cell cycle	4.867086e-7
GO:0006283	transcription-coupled nucleotide-excision repair	5.266035e-7
GO:0031123	RNA 3'-end processing	5.545838e-7
GO:0008049	male courtship behavior	6.153789e-7
GO:0006370	mRNA capping	6.172529e-7
GO:0006105	succinate metabolic process	6.788070e-7
GO:2000786	positive regulation of autophagic vacuole assembly	7.898829e-7
GO:0010591	regulation of lamellipodium assembly	9.657889e-7
GO:0043032	positive regulation of macrophage activation	9.766393e-7
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.205986e-6
GO:0006333	chromatin assembly or disassembly	1.238268e-6
GO:0001953	negative regulation of cell-matrix adhesion	1.315346e-6
GO:0008334	histone mRNA metabolic process	1.324539e-6
GO:0001937	negative regulation of endothelial cell proliferation	1.376616e-6
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	1.379589e-6
GO:0010458	exit from mitosis	1.544740e-6
GO:0006352	transcription initiation, DNA-dependent	1.664770e-6
GO:0042276	error-prone translesion synthesis	1.668503e-6
GO:0006367	transcription initiation from RNA polymerase II promoter	1.957254e-6
GO:0010812	negative regulation of cell-substrate adhesion	2.033759e-6
GO:0071156	regulation of cell cycle arrest	2.144280e-6
GO:0009452	RNA capping	2.415838e-6
GO:0016032	viral reproduction	2.737611e-6
GO:0034621	cellular macromolecular complex subunit organization	3.191917e-6
GO:0007093	mitotic cell cycle checkpoint	3.311577e-6
GO:2000119	negative regulation of sodium-dependent phosphate transport	3.326925e-6
GO:0010763	positive regulation of fibroblast migration	4.448622e-6
GO:0051444	negative regulation of ubiquitin-protein ligase activity	4.602545e-6
GO:0051208	sequestering of calcium ion	4.861809e-6
GO:0006413	translational initiation	5.810551e-6
GO:0051438	regulation of ubiquitin-protein ligase activity	6.156589e-6
GO:0044088	regulation of vacuole organization	6.305271e-6
GO:0090398	cellular senescence	6.306163e-6
GO:0035404	histone-serine phosphorylation	7.212417e-6
GO:0090281	negative regulation of calcium ion import	7.495067e-6
GO:0071584	negative regulation of zinc ion import	7.495067e-6
GO:0043030	regulation of macrophage activation	7.721590e-6
GO:0031081	nuclear pore distribution	7.846999e-6
GO:0060435	bronchiole development	8.135335e-6
GO:0042534	regulation of tumor necrosis factor biosynthetic process	8.545554e-6
GO:0071460	cellular response to cell-matrix adhesion	8.583551e-6
GO:0071585	detoxification of cadmium ion	1.000721e-5
GO:0042977	activation of JAK2 kinase activity	1.088787e-5
GO:0032914	positive regulation of transforming growth factor beta1 production	1.201916e-5
GO:0000082	G1/S transition of mitotic cell cycle	1.253640e-5
GO:0002069	columnar/cuboidal epithelial cell maturation	1.418729e-5
GO:0031103	axon regeneration	1.470362e-5
GO:0051896	regulation of protein kinase B signaling cascade	1.493087e-5
GO:0048168	regulation of neuronal synaptic plasticity	1.606809e-5
GO:0002577	regulation of antigen processing and presentation	1.631381e-5
GO:0006354	transcription elongation, DNA-dependent	1.685750e-5
GO:0051895	negative regulation of focal adhesion assembly	1.741953e-5
GO:0042255	ribosome assembly	1.925855e-5
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.020600e-5
GO:0007049	cell cycle	2.070298e-5
GO:0006353	transcription termination, DNA-dependent	2.096556e-5
GO:0051340	regulation of ligase activity	2.108748e-5
GO:0031497	chromatin assembly	2.372152e-5
GO:0051168	nuclear export	2.390803e-5
GO:0010757	negative regulation of plasminogen activation	2.398071e-5
GO:0034766	negative regulation of ion transmembrane transport	2.491330e-5
GO:0051918	negative regulation of fibrinolysis	2.500248e-5
GO:0006399	tRNA metabolic process	2.504154e-5
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	2.607509e-5
GO:0046165	alcohol biosynthetic process	2.657944e-5
GO:0071824	protein-DNA complex subunit organization	2.766995e-5
GO:0000726	non-recombinational repair	2.780699e-5
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.824992e-5
GO:0050908	detection of light stimulus involved in visual perception	2.834176e-5
GO:0090304	nucleic acid metabolic process	3.053836e-5
GO:0015734	taurine transport	3.092613e-5
GO:0031102	neuron projection regeneration	3.244889e-5
GO:0006302	double-strand break repair	3.385237e-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	3.564553e-5
GO:0006493	protein O-linked glycosylation	3.617999e-5
GO:0046449	creatinine metabolic process	3.816166e-5
GO:0006664	glycolipid metabolic process	4.071309e-5
GO:0046929	negative regulation of neurotransmitter secretion	4.190693e-5
GO:0016241	regulation of macroautophagy	4.190693e-5
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	4.378479e-5
GO:0019377	glycolipid catabolic process	5.237222e-5
GO:0046467	membrane lipid biosynthetic process	5.305766e-5
GO:0007163	establishment or maintenance of cell polarity	5.615977e-5
GO:0070535	histone H2A K63-linked ubiquitination	6.041640e-5
GO:0016476	regulation of embryonic cell shape	6.117765e-5
GO:0006349	regulation of gene expression by genetic imprinting	6.268519e-5
GO:0071423	malate transmembrane transport	6.527006e-5
GO:0015709	thiosulfate transport	6.527006e-5
GO:0006756	AMP phosphorylation	6.527006e-5
GO:0010756	positive regulation of plasminogen activation	6.675715e-5
GO:0045684	positive regulation of epidermis development	6.714548e-5
GO:0034763	negative regulation of transmembrane transport	6.837775e-5
GO:0000959	mitochondrial RNA metabolic process	6.945213e-5
GO:0006974	response to DNA damage stimulus	7.000741e-5
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	7.400543e-5
GO:0007614	short-term memory	7.400543e-5
GO:0051917	regulation of fibrinolysis	7.471636e-5
GO:0042416	dopamine biosynthetic process	7.653220e-5
GO:0000723	telomere maintenance	8.218627e-5
GO:0000255	allantoin metabolic process	8.838430e-5
GO:0034728	nucleosome organization	8.842969e-5
GO:0003341	cilium movement	8.954789e-5
GO:0043525	positive regulation of neuron apoptosis	9.280641e-5
GO:0016056	rhodopsin mediated signaling pathway	9.398452e-5
GO:0043570	maintenance of DNA repeat elements	9.433843e-5
GO:0006427	histidyl-tRNA aminoacylation	9.733990e-5
GO:0046512	sphingosine biosynthetic process	1.036256e-4
GO:0072659	protein localization in plasma membrane	1.041781e-4
GO:0019530	taurine metabolic process	1.068911e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.086719e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	1.152499e-4
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.166211e-4
GO:0006405	RNA export from nucleus	1.167656e-4
GO:0045606	positive regulation of epidermal cell differentiation	1.196601e-4
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.212911e-4
GO:0032695	negative regulation of interleukin-12 production	1.225050e-4
GO:0006310	DNA recombination	1.250812e-4
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.264722e-4
GO:0006362	transcription elongation from RNA polymerase I promoter	1.269691e-4
GO:0051351	positive regulation of ligase activity	1.277463e-4
GO:0032200	telomere organization	1.280920e-4
GO:0060052	neurofilament cytoskeleton organization	1.289640e-4
GO:0042159	lipoprotein catabolic process	1.293594e-4
GO:0045727	positive regulation of translation	1.338897e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	1.339676e-4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.373587e-4
GO:0044260	cellular macromolecule metabolic process	1.378479e-4
GO:0010758	regulation of macrophage chemotaxis	1.379312e-4
GO:0022601	menstrual cycle phase	1.439221e-4
GO:0060179	male mating behavior	1.466235e-4
GO:0060480	lung goblet cell differentiation	1.466235e-4
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.528011e-4
GO:0007009	plasma membrane organization	1.541491e-4
GO:0031507	heterochromatin formation	1.589718e-4
GO:0051320	S phase	1.599711e-4
GO:0006406	mRNA export from nucleus	1.626572e-4
GO:0071675	regulation of mononuclear cell migration	1.631364e-4
GO:0010759	positive regulation of macrophage chemotaxis	1.654427e-4
GO:0070979	protein K11-linked ubiquitination	1.662709e-4
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	1.745263e-4
GO:0003016	respiratory system process	1.779070e-4
GO:0043277	apoptotic cell clearance	1.807878e-4
GO:0055098	response to low-density lipoprotein particle stimulus	1.815873e-4
GO:0006369	termination of RNA polymerase II transcription	1.818676e-4
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.889464e-4
GO:0031959	mineralocorticoid receptor signaling pathway	2.064496e-4
GO:0006412	translation	2.076111e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	2.171127e-4
GO:0006401	RNA catabolic process	2.203600e-4
GO:0006107	oxaloacetate metabolic process	2.279479e-4
GO:0006610	ribosomal protein import into nucleus	2.317059e-4
GO:0032057	negative regulation of translational initiation in response to stress	2.480570e-4
GO:0010596	negative regulation of endothelial cell migration	2.500508e-4
GO:0030194	positive regulation of blood coagulation	2.563046e-4
GO:0002316	follicular B cell differentiation	2.651872e-4
GO:0006549	isoleucine metabolic process	2.651872e-4
GO:0035067	negative regulation of histone acetylation	2.660366e-4
GO:0070682	proteasome regulatory particle assembly	2.742683e-4
GO:0007113	endomitotic cell cycle	2.763257e-4
GO:0006600	creatine metabolic process	2.846669e-4
GO:0009225	nucleotide-sugar metabolic process	2.851793e-4
GO:0071402	cellular response to lipoprotein particle stimulus	3.046351e-4
GO:0031124	mRNA 3'-end processing	3.054003e-4
GO:0030538	embryonic genitalia morphogenesis	3.102587e-4
GO:0016071	mRNA metabolic process	3.126124e-4
GO:0006103	2-oxoglutarate metabolic process	3.179614e-4
GO:0006396	RNA processing	3.515537e-4
GO:0033693	neurofilament bundle assembly	3.525945e-4
GO:0034622	cellular macromolecular complex assembly	3.579856e-4
GO:0042976	activation of Janus kinase activity	3.612460e-4
GO:0007050	cell cycle arrest	3.636205e-4
GO:0071514	genetic imprinting	3.763112e-4
GO:0006390	transcription from mitochondrial promoter	3.810773e-4
GO:0032908	regulation of transforming growth factor beta1 production	3.865084e-4
GO:0045647	negative regulation of erythrocyte differentiation	3.868203e-4
GO:0000375	RNA splicing, via transesterification reactions	4.015677e-4
GO:0033119	negative regulation of RNA splicing	4.031128e-4
GO:0071622	regulation of granulocyte chemotaxis	4.135340e-4
GO:0000086	G2/M transition of mitotic cell cycle	4.160957e-4
GO:0051589	negative regulation of neurotransmitter transport	4.309025e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	4.444155e-4
GO:0019303	D-ribose catabolic process	4.533831e-4
GO:0035083	cilium axoneme assembly	4.667493e-4
GO:0030148	sphingolipid biosynthetic process	4.834095e-4
GO:0019276	UDP-N-acetylgalactosamine metabolic process	4.922968e-4
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	4.937145e-4
GO:0015780	nucleotide-sugar transport	5.011760e-4
GO:0070613	regulation of protein processing	5.028515e-4
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	5.037650e-4
GO:0030838	positive regulation of actin filament polymerization	5.107553e-4
GO:0042423	catecholamine biosynthetic process	5.204132e-4
GO:0000279	M phase	5.219944e-4
GO:0000084	S phase of mitotic cell cycle	5.426599e-4
GO:0032055	negative regulation of translation in response to stress	5.779966e-4
GO:0051488	activation of anaphase-promoting complex activity	5.804968e-4
GO:0000209	protein polyubiquitination	5.812937e-4
GO:0065002	intracellular protein transmembrane transport	5.883808e-4
GO:0042780	tRNA 3'-end processing	6.101919e-4
GO:0043526	neuroprotection	6.208094e-4
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	6.336750e-4
GO:0035722	interleukin-12-mediated signaling pathway	6.336750e-4
GO:0003009	skeletal muscle contraction	6.629595e-4
GO:0006101	citrate metabolic process	6.675428e-4
GO:0051028	mRNA transport	6.733370e-4
GO:0007088	regulation of mitosis	6.759383e-4
GO:0006097	glyoxylate cycle	6.863517e-4
GO:0046544	development of secondary male sexual characteristics	6.976966e-4
GO:0043631	RNA polyadenylation	7.059998e-4
GO:0014012	peripheral nervous system axon regeneration	7.244233e-4
GO:0030704	vitelline membrane formation	7.340737e-4
GO:0007126	meiosis	7.412811e-4
GO:0010957	negative regulation of vitamin D biosynthetic process	7.420915e-4
GO:0019047	provirus integration	7.473780e-4
GO:0045083	negative regulation of interleukin-12 biosynthetic process	7.872402e-4
GO:0021530	spinal cord oligodendrocyte cell fate specification	7.872402e-4
GO:0022415	viral reproductive process	7.942287e-4
GO:0007442	hindgut morphogenesis	8.005063e-4
GO:0006363	termination of RNA polymerase I transcription	8.056760e-4
GO:0042104	positive regulation of activated T cell proliferation	8.149796e-4
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	8.399671e-4
GO:0019083	viral transcription	8.433432e-4
GO:0007098	centrosome cycle	8.465066e-4
GO:0030719	P granule organization	8.532267e-4
GO:0090130	tissue migration	8.681762e-4
GO:0070231	T cell apoptosis	9.006848e-4
GO:0050680	negative regulation of epithelial cell proliferation	9.249603e-4
GO:0016339	calcium-dependent cell-cell adhesion	9.488768e-4
GO:0051293	establishment of spindle localization	9.596512e-4
GO:0046939	nucleotide phosphorylation	9.805689e-4
GO:0050820	positive regulation of coagulation	9.815071e-4
GO:2000330	positive regulation of T-helper 17 cell lineage commitment	9.847507e-4
GO:2000318	positive regulation of T-helper 17 type immune response	9.847507e-4
GO:0010955	negative regulation of protein processing	1.004333e-3
GO:0046511	sphinganine biosynthetic process	1.022506e-3
GO:0000226	microtubule cytoskeleton organization	1.029535e-3
GO:0006643	membrane lipid metabolic process	1.036365e-3
GO:0031397	negative regulation of protein ubiquitination	1.037094e-3
GO:0065004	protein-DNA complex assembly	1.040760e-3
GO:0010631	epithelial cell migration	1.065777e-3
GO:0048524	positive regulation of viral reproduction	1.087096e-3
GO:0009226	nucleotide-sugar biosynthetic process	1.089068e-3
GO:0018212	peptidyl-tyrosine modification	1.108913e-3
GO:0042407	cristae formation	1.126759e-3
GO:0035803	egg coat formation	1.126759e-3
GO:0072592	oxygen metabolic process	1.145771e-3
GO:0010966	regulation of phosphate transport	1.145771e-3
GO:0033002	muscle cell proliferation	1.154671e-3
GO:0006687	glycosphingolipid metabolic process	1.160809e-3
GO:0051301	cell division	1.168652e-3
GO:0030010	establishment of cell polarity	1.173373e-3
GO:0040001	establishment of mitotic spindle localization	1.199561e-3
GO:0000724	double-strand break repair via homologous recombination	1.246133e-3
GO:0006361	transcription initiation from RNA polymerase I promoter	1.260058e-3
GO:2000774	positive regulation of cellular senescence	1.266736e-3
GO:0035986	senescence-associated heterochromatin focus formation	1.266736e-3
GO:0060556	regulation of vitamin D biosynthetic process	1.279819e-3
GO:0033007	negative regulation of mast cell activation involved in immune response	1.285464e-3
GO:0051321	meiotic cell cycle	1.301646e-3
GO:0007341	penetration of zona pellucida	1.317373e-3
GO:0006233	dTDP biosynthetic process	1.318402e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	1.381746e-3
GO:0050434	positive regulation of viral transcription	1.409240e-3
GO:0018108	peptidyl-tyrosine phosphorylation	1.418760e-3
GO:0030889	negative regulation of B cell proliferation	1.445842e-3
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	1.446452e-3
GO:0071480	cellular response to gamma radiation	1.464810e-3
GO:0008366	axon ensheathment	1.492495e-3
GO:0032890	regulation of organic acid transport	1.505768e-3
GO:0016567	protein ubiquitination	1.518503e-3
GO:0000725	recombinational repair	1.554751e-3
GO:0051726	regulation of cell cycle	1.583315e-3
GO:0060033	anatomical structure regression	1.596939e-3
GO:0006538	glutamate catabolic process	1.599260e-3
GO:0043633	polyadenylation-dependent RNA catabolic process	1.653904e-3
GO:0032287	peripheral nervous system myelin maintenance	1.677168e-3
GO:0051549	positive regulation of keratinocyte migration	1.682020e-3
GO:0006911	phagocytosis, engulfment	1.708613e-3
GO:0006414	translational elongation	1.728536e-3
GO:0046782	regulation of viral transcription	1.785014e-3
GO:0060576	intestinal epithelial cell development	1.822516e-3
GO:0008054	cyclin catabolic process	1.824883e-3
GO:0050881	musculoskeletal movement	1.840212e-3
GO:0000712	resolution of meiotic recombination intermediates	1.841858e-3
GO:0070830	tight junction assembly	1.867604e-3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	1.893049e-3
GO:0009138	pyrimidine nucleoside diphosphate metabolic process	1.917688e-3
GO:0002769	natural killer cell inhibitory signaling pathway	1.968277e-3
GO:0046513	ceramide biosynthetic process	1.995251e-3
GO:0000132	establishment of mitotic spindle orientation	2.006860e-3
GO:0006382	adenosine to inosine editing	2.031854e-3
GO:0006689	ganglioside catabolic process	2.054198e-3
GO:0008033	tRNA processing	2.062706e-3
GO:0042572	retinol metabolic process	2.085344e-3
GO:0050769	positive regulation of neurogenesis	2.092485e-3
GO:0019673	GDP-mannose metabolic process	2.102137e-3
GO:0015696	ammonium transport	2.136997e-3
GO:0070206	protein trimerization	2.249820e-3
GO:0002312	B cell activation involved in immune response	2.278861e-3
GO:0006573	valine metabolic process	2.330045e-3
GO:0002344	B cell affinity maturation	2.346531e-3
GO:2000467	positive regulation of glycogen (starch) synthase activity	2.355937e-3
GO:0048678	response to axon injury	2.380657e-3
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	2.453325e-3
GO:0006139	nucleobase-containing compound metabolic process	2.484103e-3
GO:0045879	negative regulation of smoothened signaling pathway	2.554319e-3
GO:0019985	translesion synthesis	2.590416e-3
GO:0003219	cardiac right ventricle formation	2.590416e-3
GO:0006684	sphingomyelin metabolic process	2.634688e-3
GO:0071422	succinate transmembrane transport	2.715849e-3
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	2.738704e-3
GO:0031129	inductive cell-cell signaling	2.738704e-3
GO:0014827	intestine smooth muscle contraction	2.789392e-3
GO:2000737	negative regulation of stem cell differentiation	2.795916e-3
GO:0035020	regulation of Rac protein signal transduction	2.797910e-3
GO:0006665	sphingolipid metabolic process	2.918493e-3
GO:0032446	protein modification by small protein conjugation	2.966641e-3
GO:0042552	myelination	2.995048e-3
GO:0035411	catenin import into nucleus	3.001088e-3
GO:0032107	regulation of response to nutrient levels	3.018411e-3
GO:0007346	regulation of mitotic cell cycle	3.048281e-3
GO:2000191	regulation of fatty acid transport	3.103671e-3
GO:0006337	nucleosome disassembly	3.121319e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	3.155280e-3
GO:0008089	anterograde axon cargo transport	3.169668e-3
GO:0046006	regulation of activated T cell proliferation	3.172595e-3
GO:0045919	positive regulation of cytolysis	3.204314e-3
GO:0043039	tRNA aminoacylation	3.212337e-3
GO:0071344	diphosphate metabolic process	3.218601e-3
GO:0030187	melatonin biosynthetic process	3.218601e-3
GO:0046931	pore complex assembly	3.443318e-3
GO:0030221	basophil differentiation	3.467032e-3
GO:2000379	positive regulation of reactive oxygen species metabolic process	3.486549e-3
GO:0043616	keratinocyte proliferation	3.536227e-3
GO:0001936	regulation of endothelial cell proliferation	3.589957e-3
GO:0070207	protein homotrimerization	3.596745e-3
GO:0060534	trachea cartilage development	3.604619e-3
GO:0051298	centrosome duplication	3.678880e-3
GO:0048194	Golgi vesicle budding	3.688612e-3
GO:0046479	glycosphingolipid catabolic process	3.688612e-3
GO:0006913	nucleocytoplasmic transport	3.713870e-3
GO:0001893	maternal placenta development	3.733579e-3
GO:0046520	sphingoid biosynthetic process	3.744967e-3
GO:0071636	positive regulation of transforming growth factor beta production	3.845772e-3
GO:0045653	negative regulation of megakaryocyte differentiation	3.896845e-3
GO:0055017	cardiac muscle tissue growth	3.922874e-3
GO:0009988	cell-cell recognition	4.112029e-3
GO:0006108	malate metabolic process	4.167103e-3
GO:0006334	nucleosome assembly	4.199097e-3
GO:2000177	regulation of neural precursor cell proliferation	4.269602e-3
GO:0043297	apical junction assembly	4.305575e-3
GO:0050772	positive regulation of axonogenesis	4.310060e-3
GO:0018293	protein-FAD linkage	4.362245e-3
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	4.362245e-3
GO:0010963	regulation of L-arginine import	4.362245e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	4.362245e-3
GO:0021986	habenula development	4.396748e-3
GO:0001561	fatty acid alpha-oxidation	4.546090e-3
GO:0051297	centrosome organization	4.563155e-3
GO:0045556	positive regulation of TRAIL biosynthetic process	4.641710e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	4.691423e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	4.728447e-3
GO:0010693	negative regulation of alkaline phosphatase activity	4.728447e-3
GO:0071103	DNA conformation change	4.755634e-3
GO:0043648	dicarboxylic acid metabolic process	4.761102e-3
GO:0000216	M/G1 transition of mitotic cell cycle	4.860810e-3
GO:0006686	sphingomyelin biosynthetic process	4.918868e-3
GO:0045116	protein neddylation	4.946254e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	4.982169e-3
GO:0009313	oligosaccharide catabolic process	4.993129e-3
GO:0032984	macromolecular complex disassembly	5.002429e-3
GO:0002329	pre-B cell differentiation	5.052892e-3
GO:0034623	cellular macromolecular complex disassembly	5.084685e-3
GO:0019228	regulation of action potential in neuron	5.100547e-3
GO:0006612	protein targeting to membrane	5.132120e-3
GO:0015074	DNA integration	5.170556e-3
GO:0010720	positive regulation of cell development	5.232421e-3
GO:0072274	metanephric glomerular basement membrane development	5.233928e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	5.233928e-3
GO:0048677	axon extension involved in regeneration	5.233928e-3
GO:0018931	naphthalene metabolic process	5.233928e-3
GO:0035284	brain segmentation	5.263951e-3
GO:0060419	heart growth	5.365347e-3
GO:0048167	regulation of synaptic plasticity	5.391073e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	5.416900e-3
GO:0070995	NADPH oxidation	5.432148e-3
GO:0003218	cardiac left ventricle formation	5.432148e-3
GO:0035814	negative regulation of renal sodium excretion	5.453243e-3
GO:0045939	negative regulation of steroid metabolic process	5.473623e-3
GO:0015801	aromatic amino acid transport	5.487684e-3
GO:0055094	response to lipoprotein stimulus	5.504268e-3
GO:0060482	lobar bronchus development	5.548681e-3
GO:0043985	histone H4-R3 methylation	5.548681e-3
GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	5.548681e-3
GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	5.548681e-3
GO:0010894	negative regulation of steroid biosynthetic process	5.708628e-3
GO:0019060	intracellular transport of viral proteins in host cell	5.724285e-3
GO:0033004	negative regulation of mast cell activation	5.734555e-3
GO:0015804	neutral amino acid transport	5.767344e-3
GO:0051169	nuclear transport	5.777363e-3
GO:0045292	nuclear mRNA cis splicing, via spliceosome	5.813574e-3
GO:0030833	regulation of actin filament polymerization	5.867614e-3
GO:0006415	translational termination	5.976916e-3
GO:0060038	cardiac muscle cell proliferation	6.133955e-3
GO:0022417	protein maturation by protein folding	6.207424e-3
GO:0006403	RNA localization	6.257998e-3
GO:0048619	embryonic hindgut morphogenesis	6.290609e-3
GO:0008611	ether lipid biosynthetic process	6.462771e-3
GO:0006477	protein sulfation	6.507719e-3
GO:0042053	regulation of dopamine metabolic process	6.533977e-3
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	6.579873e-3
GO:0018352	protein-pyridoxal-5-phosphate linkage	6.717439e-3
GO:0006418	tRNA aminoacylation for protein translation	6.755074e-3
GO:0006323	DNA packaging	6.981245e-3
GO:0043535	regulation of blood vessel endothelial cell migration	7.036835e-3
GO:0043217	myelin maintenance	7.042275e-3
GO:0019048	virus-host interaction	7.107281e-3
GO:0002544	chronic inflammatory response	7.165985e-3
GO:0010940	positive regulation of necrotic cell death	7.187479e-3
GO:0021515	cell differentiation in spinal cord	7.223761e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.240678e-3
GO:0051292	nuclear pore complex assembly	7.247684e-3
GO:0042694	muscle cell fate specification	7.247684e-3
GO:0019323	pentose catabolic process	7.247684e-3
GO:0002339	B cell selection	7.247684e-3
GO:0016572	histone phosphorylation	7.272727e-3
GO:0006556	S-adenosylmethionine biosynthetic process	7.273085e-3
GO:0035094	response to nicotine	7.277367e-3
GO:0045333	cellular respiration	7.332614e-3
GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	7.443102e-3
GO:0019376	galactolipid catabolic process	7.443102e-3
GO:0031023	microtubule organizing center organization	7.503873e-3
GO:0033554	cellular response to stress	7.591581e-3
GO:0050658	RNA transport	7.637499e-3
GO:0050686	negative regulation of mRNA processing	7.642883e-3
GO:2000465	regulation of glycogen (starch) synthase activity	7.647611e-3
GO:0006402	mRNA catabolic process	7.669121e-3
GO:0008078	mesodermal cell migration	7.707798e-3
GO:0032185	septin cytoskeleton organization	7.707798e-3
GO:0034637	cellular carbohydrate biosynthetic process	7.787227e-3
GO:0031297	replication fork processing	7.809477e-3
GO:0001881	receptor recycling	7.917376e-3
GO:0031104	dendrite regeneration	8.066244e-3
GO:0031508	centromeric heterochromatin formation	8.066244e-3
GO:0043382	positive regulation of memory T cell differentiation	8.159647e-3
GO:0010498	proteasomal protein catabolic process	8.246851e-3
GO:0042069	regulation of catecholamine metabolic process	8.353663e-3
GO:0006670	sphingosine metabolic process	8.376842e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	8.424536e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	8.441034e-3
GO:0006667	sphinganine metabolic process	8.441034e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	8.453573e-3
GO:0043523	regulation of neuron apoptosis	8.493691e-3
GO:0019896	axon transport of mitochondrion	8.536142e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	8.672063e-3
GO:0031118	rRNA pseudouridine synthesis	8.701731e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0007088	regulation of mitosis	4.420078e-13
GO:0014902	myotube differentiation	3.526030e-12
GO:0045840	positive regulation of mitosis	1.135514e-11
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	8.416602e-11
GO:0007346	regulation of mitotic cell cycle	1.210589e-10
GO:0010799	regulation of peptidyl-threonine phosphorylation	2.141762e-10
GO:0051450	myoblast proliferation	6.888799e-10
GO:0010467	gene expression	2.058895e-9
GO:0010564	regulation of cell cycle process	8.529110e-9
GO:0043973	histone H3-K4 acetylation	1.051110e-8
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.051110e-8
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.051110e-8
GO:0042760	very long-chain fatty acid catabolic process	1.058705e-8
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.266917e-8
GO:0090068	positive regulation of cell cycle process	1.812038e-8
GO:0035019	somatic stem cell maintenance	2.439157e-8
GO:0035914	skeletal muscle cell differentiation	2.507623e-8
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	2.624565e-8
GO:0060840	artery development	4.227257e-8
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	6.217255e-8
GO:0031016	pancreas development	7.808349e-8
GO:0002536	respiratory burst involved in inflammatory response	8.403031e-8
GO:0034447	very-low-density lipoprotein particle clearance	1.082281e-7
GO:0014904	myotube cell development	2.163231e-7
GO:0060509	Type I pneumocyte differentiation	2.319856e-7
GO:0021533	cell differentiation in hindbrain	2.980526e-7
GO:0010900	negative regulation of phosphatidylcholine catabolic process	3.141362e-7
GO:0035674	tricarboxylic acid transmembrane transport	3.492429e-7
GO:0016070	RNA metabolic process	4.961036e-7
GO:0044260	cellular macromolecule metabolic process	5.902747e-7
GO:0090304	nucleic acid metabolic process	6.009753e-7
GO:0048844	artery morphogenesis	6.716604e-7
GO:0009889	regulation of biosynthetic process	6.756719e-7
GO:0046984	regulation of hemoglobin biosynthetic process	7.090027e-7
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	7.900699e-7
GO:0035272	exocrine system development	8.320308e-7
GO:0006401	RNA catabolic process	8.759538e-7
GO:0071354	cellular response to interleukin-6	9.141512e-7
GO:0044237	cellular metabolic process	9.439644e-7
GO:0045862	positive regulation of proteolysis	1.034371e-6
GO:0000726	non-recombinational repair	1.215309e-6
GO:0006303	double-strand break repair via nonhomologous end joining	1.256714e-6
GO:0007067	mitosis	1.836082e-6
GO:0048863	stem cell differentiation	2.087197e-6
GO:0000226	microtubule cytoskeleton organization	2.133725e-6
GO:0006139	nucleobase-containing compound metabolic process	2.248028e-6
GO:0045596	negative regulation of cell differentiation	2.278393e-6
GO:0032270	positive regulation of cellular protein metabolic process	2.312087e-6
GO:0031326	regulation of cellular biosynthetic process	2.313241e-6
GO:0051247	positive regulation of protein metabolic process	2.374680e-6
GO:0071243	cellular response to arsenic-containing substance	2.792059e-6
GO:0060766	negative regulation of androgen receptor signaling pathway	3.023700e-6
GO:0048285	organelle fission	3.297177e-6
GO:0060741	prostate gland stromal morphogenesis	3.362559e-6
GO:0048864	stem cell development	3.487678e-6
GO:0001764	neuron migration	3.663049e-6
GO:0000387	spliceosomal snRNP assembly	3.768727e-6
GO:0000087	M phase of mitotic cell cycle	3.874863e-6
GO:0014812	muscle cell migration	4.206778e-6
GO:0043170	macromolecule metabolic process	4.222550e-6
GO:0033238	regulation of cellular amine metabolic process	4.256502e-6
GO:0046785	microtubule polymerization	4.486108e-6
GO:0035630	bone mineralization involved in bone maturation	4.486108e-6
GO:0000089	mitotic metaphase	4.827022e-6
GO:0071034	CUT catabolic process	5.292461e-6
GO:0010994	free ubiquitin chain polymerization	5.292461e-6
GO:0010556	regulation of macromolecule biosynthetic process	5.530698e-6
GO:0019827	stem cell maintenance	6.039615e-6
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	6.167285e-6
GO:0042769	DNA damage response, detection of DNA damage	6.232567e-6
GO:0031017	exocrine pancreas development	6.495973e-6
GO:0008334	histone mRNA metabolic process	6.820555e-6
GO:0016055	Wnt receptor signaling pathway	7.753458e-6
GO:0008152	metabolic process	8.848701e-6
GO:2000112	regulation of cellular macromolecule biosynthetic process	9.108496e-6
GO:0008380	RNA splicing	9.974226e-6
GO:0014911	positive regulation of smooth muscle cell migration	1.045933e-5
GO:0051651	maintenance of location in cell	1.100426e-5
GO:0051235	maintenance of location	1.101010e-5
GO:0060463	lung lobe morphogenesis	1.175399e-5
GO:0006396	RNA processing	1.206451e-5
GO:0043403	skeletal muscle tissue regeneration	1.213212e-5
GO:0044238	primary metabolic process	1.272772e-5
GO:0051171	regulation of nitrogen compound metabolic process	1.329023e-5
GO:0006275	regulation of DNA replication	1.352588e-5
GO:0033239	negative regulation of cellular amine metabolic process	1.355656e-5
GO:0034661	ncRNA catabolic process	1.372510e-5
GO:0015746	citrate transport	1.420497e-5
GO:0080164	regulation of nitric oxide metabolic process	1.458527e-5
GO:0007057	spindle assembly involved in female meiosis I	1.458527e-5
GO:0046777	protein autophosphorylation	1.638777e-5
GO:0042753	positive regulation of circadian rhythm	1.791346e-5
GO:0034641	cellular nitrogen compound metabolic process	1.875173e-5
GO:0048538	thymus development	1.928554e-5
GO:0071044	histone mRNA catabolic process	2.021318e-5
GO:0034392	negative regulation of smooth muscle cell apoptosis	2.022027e-5
GO:0030970	retrograde protein transport, ER to cytosol	2.080766e-5
GO:0031536	positive regulation of exit from mitosis	2.156144e-5
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	2.389887e-5
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	2.389887e-5
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	2.389887e-5
GO:0001676	long-chain fatty acid metabolic process	2.581067e-5
GO:0043931	ossification involved in bone maturation	2.638611e-5
GO:0030071	regulation of mitotic metaphase/anaphase transition	2.775428e-5
GO:0042104	positive regulation of activated T cell proliferation	2.807581e-5
GO:0032007	negative regulation of TOR signaling cascade	2.960979e-5
GO:0009892	negative regulation of metabolic process	3.072126e-5
GO:0016071	mRNA metabolic process	3.254271e-5
GO:0046890	regulation of lipid biosynthetic process	3.378148e-5
GO:0051005	negative regulation of lipoprotein lipase activity	3.390541e-5
GO:0034382	chylomicron remnant clearance	3.390541e-5
GO:0009057	macromolecule catabolic process	3.534176e-5
GO:0060696	regulation of phospholipid catabolic process	3.559922e-5
GO:0060736	prostate gland growth	3.565835e-5
GO:0050995	negative regulation of lipid catabolic process	3.657295e-5
GO:0071422	succinate transmembrane transport	3.845123e-5
GO:0046426	negative regulation of JAK-STAT cascade	3.930469e-5
GO:0060319	primitive erythrocyte differentiation	4.096227e-5
GO:0060192	negative regulation of lipase activity	4.098473e-5
GO:0006357	regulation of transcription from RNA polymerase II promoter	4.098969e-5
GO:0006807	nitrogen compound metabolic process	4.582738e-5
GO:0021522	spinal cord motor neuron differentiation	4.930215e-5
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	4.957693e-5
GO:0032784	regulation of transcription elongation, DNA-dependent	5.197414e-5
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	5.748026e-5
GO:0070541	response to platinum ion	5.873912e-5
GO:0070741	response to interleukin-6	5.949032e-5
GO:0070977	bone maturation	6.204543e-5
GO:2000381	negative regulation of mesoderm development	6.360741e-5
GO:0031129	inductive cell-cell signaling	6.535724e-5
GO:0060510	Type II pneumocyte differentiation	6.641766e-5
GO:0021697	cerebellar cortex formation	6.644681e-5
GO:0051258	protein polymerization	7.135390e-5
GO:0045595	regulation of cell differentiation	7.287512e-5
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	7.576855e-5
GO:0015931	nucleobase-containing compound transport	7.606559e-5
GO:0009059	macromolecule biosynthetic process	7.690191e-5
GO:0019219	regulation of nucleobase-containing compound metabolic process	7.747126e-5
GO:0002320	lymphoid progenitor cell differentiation	8.091792e-5
GO:0048713	regulation of oligodendrocyte differentiation	8.579513e-5
GO:0007398	ectoderm development	8.719397e-5
GO:0045740	positive regulation of DNA replication	8.782614e-5
GO:0002328	pro-B cell differentiation	8.935279e-5
GO:0021515	cell differentiation in spinal cord	8.953442e-5
GO:0050810	regulation of steroid biosynthetic process	9.009878e-5
GO:0045732	positive regulation of protein catabolic process	9.016527e-5
GO:0032900	negative regulation of neurotrophin production	9.194669e-5
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	9.194669e-5
GO:0032244	positive regulation of nucleoside transport	9.194669e-5
GO:0010468	regulation of gene expression	9.203553e-5
GO:0006397	mRNA processing	9.601761e-5
GO:0000278	mitotic cell cycle	9.738791e-5
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	9.761053e-5
GO:2000172	regulation of branching morphogenesis of a nerve	9.761053e-5
GO:0055123	digestive system development	9.896534e-5
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	9.905117e-5
GO:0009890	negative regulation of biosynthetic process	9.972568e-5
GO:0042752	regulation of circadian rhythm	1.009902e-4
GO:0021936	regulation of cerebellar granule cell precursor proliferation	1.032673e-4
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.035416e-4
GO:0001649	osteoblast differentiation	1.047328e-4
GO:0071322	cellular response to carbohydrate stimulus	1.057558e-4
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	1.110596e-4
GO:0044265	cellular macromolecule catabolic process	1.146315e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	1.160106e-4
GO:0060992	response to fungicide	1.171107e-4
GO:0010638	positive regulation of organelle organization	1.208560e-4
GO:0031331	positive regulation of cellular catabolic process	1.219502e-4
GO:0046006	regulation of activated T cell proliferation	1.225317e-4
GO:0010519	negative regulation of phospholipase activity	1.299714e-4
GO:0006168	adenine salvage	1.299714e-4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.304767e-4
GO:0002244	hemopoietic progenitor cell differentiation	1.311948e-4
GO:0006699	bile acid biosynthetic process	1.333153e-4
GO:0034645	cellular macromolecule biosynthetic process	1.355260e-4
GO:0001522	pseudouridine synthesis	1.367608e-4
GO:0048333	mesodermal cell differentiation	1.391142e-4
GO:0006412	translation	1.565804e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	1.602664e-4
GO:0060765	regulation of androgen receptor signaling pathway	1.607220e-4
GO:0060458	right lung development	1.624647e-4
GO:0021702	cerebellar Purkinje cell differentiation	1.637789e-4
GO:0034391	regulation of smooth muscle cell apoptosis	1.647008e-4
GO:0071877	regulation of adrenergic receptor signaling pathway	1.711481e-4
GO:0031327	negative regulation of cellular biosynthetic process	1.734861e-4
GO:0006284	base-excision repair	1.759259e-4
GO:0045445	myoblast differentiation	1.793848e-4
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	1.828290e-4
GO:0060644	mammary gland epithelial cell differentiation	1.859579e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	1.905430e-4
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	1.909719e-4
GO:0010656	negative regulation of muscle cell apoptosis	1.948714e-4
GO:0014050	negative regulation of glutamate secretion	1.964377e-4
GO:0051252	regulation of RNA metabolic process	2.027339e-4
GO:0061136	regulation of proteasomal protein catabolic process	2.070382e-4
GO:0000279	M phase	2.096070e-4
GO:0048566	embryonic digestive tract development	2.269230e-4
GO:0045833	negative regulation of lipid metabolic process	2.339705e-4
GO:0006116	NADH oxidation	2.345986e-4
GO:0046325	negative regulation of glucose import	2.352623e-4
GO:0032077	positive regulation of deoxyribonuclease activity	2.360593e-4
GO:0051323	metaphase	2.365537e-4
GO:0070979	protein K11-linked ubiquitination	2.377335e-4
GO:0048012	hepatocyte growth factor receptor signaling pathway	2.438826e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	2.463526e-4
GO:0021696	cerebellar cortex morphogenesis	2.540914e-4
GO:0051257	spindle midzone assembly involved in meiosis	2.594976e-4
GO:0051301	cell division	2.663847e-4
GO:0006355	regulation of transcription, DNA-dependent	2.685284e-4
GO:0021517	ventral spinal cord development	2.737763e-4
GO:0006403	RNA localization	2.761243e-4
GO:0071773	cellular response to BMP stimulus	2.833729e-4
GO:0045540	regulation of cholesterol biosynthetic process	2.836392e-4
GO:0060070	canonical Wnt receptor signaling pathway	2.877605e-4
GO:0031324	negative regulation of cellular metabolic process	2.936140e-4
GO:0060574	intestinal epithelial cell maturation	3.035557e-4
GO:0051093	negative regulation of developmental process	3.181266e-4
GO:0031133	regulation of axon diameter	3.234599e-4
GO:0051172	negative regulation of nitrogen compound metabolic process	3.320270e-4
GO:0016075	rRNA catabolic process	3.336672e-4
GO:0010458	exit from mitosis	3.377606e-4
GO:0010829	negative regulation of glucose transport	3.386597e-4
GO:0051052	regulation of DNA metabolic process	3.647817e-4
GO:0007040	lysosome organization	3.712973e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	3.726327e-4
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	3.800684e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	3.853408e-4
GO:0019216	regulation of lipid metabolic process	3.887490e-4
GO:0045725	positive regulation of glycogen biosynthetic process	3.970970e-4
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	4.152649e-4
GO:0032878	regulation of establishment or maintenance of cell polarity	4.197830e-4
GO:0031109	microtubule polymerization or depolymerization	4.197830e-4
GO:0032864	activation of Cdc42 GTPase activity	4.208547e-4
GO:0044249	cellular biosynthetic process	4.293983e-4
GO:0034241	positive regulation of macrophage fusion	4.386233e-4
GO:0031468	nuclear envelope reassembly	4.386233e-4
GO:0050793	regulation of developmental process	4.494609e-4
GO:0045187	regulation of circadian sleep/wake cycle, sleep	4.499364e-4
GO:0060348	bone development	4.592293e-4
GO:0006561	proline biosynthetic process	4.661484e-4
GO:0035414	negative regulation of catenin import into nucleus	4.738128e-4
GO:0009058	biosynthetic process	4.790021e-4
GO:0019835	cytolysis	4.885615e-4
GO:0045892	negative regulation of transcription, DNA-dependent	4.890429e-4
GO:0060981	cell migration involved in coronary angiogenesis	4.938493e-4
GO:0046038	GMP catabolic process	4.938493e-4
GO:0071670	smooth muscle cell chemotaxis	4.938493e-4
GO:0006178	guanine salvage	4.938493e-4
GO:0032263	GMP salvage	4.938493e-4
GO:0032264	IMP salvage	4.938493e-4
GO:0010629	negative regulation of gene expression	4.989802e-4
GO:0010001	glial cell differentiation	5.087415e-4
GO:0060688	regulation of morphogenesis of a branching structure	5.183358e-4
GO:0006402	mRNA catabolic process	5.196938e-4
GO:0080090	regulation of primary metabolic process	5.212809e-4
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	5.403265e-4
GO:0001708	cell fate specification	5.435534e-4
GO:0051640	organelle localization	5.482137e-4
GO:0007017	microtubule-based process	5.546717e-4
GO:0046037	GMP metabolic process	5.561372e-4
GO:0051152	positive regulation of smooth muscle cell differentiation	5.662906e-4
GO:0051310	metaphase plate congression	5.714209e-4
GO:0051642	centrosome localization	5.848652e-4
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	5.856872e-4
GO:0060662	salivary gland cavitation	6.031043e-4
GO:0090201	negative regulation of release of cytochrome c from mitochondria	6.141902e-4
GO:0010605	negative regulation of macromolecule metabolic process	6.163226e-4
GO:0000212	meiotic spindle organization	6.199222e-4
GO:0010660	regulation of muscle cell apoptosis	6.204943e-4
GO:0042176	regulation of protein catabolic process	6.207906e-4
GO:2000179	positive regulation of neural precursor cell proliferation	6.237261e-4
GO:0015986	ATP synthesis coupled proton transport	6.343851e-4
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	6.483003e-4
GO:0071294	cellular response to zinc ion	6.510037e-4
GO:0051574	positive regulation of histone H3-K9 methylation	6.510037e-4
GO:0007096	regulation of exit from mitosis	6.510037e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	6.697975e-4
GO:0032851	positive regulation of Rab GTPase activity	6.900703e-4
GO:0006266	DNA ligation	6.939700e-4
GO:0046823	negative regulation of nucleocytoplasmic transport	6.963876e-4
GO:0002377	immunoglobulin production	7.084035e-4
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	7.161482e-4
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	7.284897e-4
GO:0032536	regulation of cell projection size	7.365025e-4
GO:0009896	positive regulation of catabolic process	7.462870e-4
GO:2000173	negative regulation of branching morphogenesis of a nerve	7.485161e-4
GO:0006420	arginyl-tRNA aminoacylation	7.485161e-4
GO:0032313	regulation of Rab GTPase activity	7.497841e-4
GO:0006641	triglyceride metabolic process	7.606923e-4
GO:0060764	cell-cell signaling involved in mammary gland development	7.616568e-4
GO:0018924	mandelate metabolic process	7.616568e-4
GO:0048523	negative regulation of cellular process	7.784999e-4
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	7.823400e-4
GO:0018026	peptidyl-lysine monomethylation	7.823400e-4
GO:0008333	endosome to lysosome transport	7.871006e-4
GO:0010232	vascular transport	7.943439e-4
GO:2000384	negative regulation of ectoderm development	7.943439e-4
GO:0014910	regulation of smooth muscle cell migration	8.014145e-4
GO:0002440	production of molecular mediator of immune response	8.085099e-4
GO:0031323	regulation of cellular metabolic process	8.208503e-4
GO:0060174	limb bud formation	8.265739e-4
GO:0060973	cell migration involved in heart development	8.365659e-4
GO:0007093	mitotic cell cycle checkpoint	8.641631e-4
GO:0007625	grooming behavior	8.733212e-4
GO:0071333	cellular response to glucose stimulus	8.752533e-4
GO:0010823	negative regulation of mitochondrion organization	8.800200e-4
GO:0045653	negative regulation of megakaryocyte differentiation	8.813324e-4
GO:0006657	CDP-choline pathway	8.813324e-4
GO:0051726	regulation of cell cycle	8.865468e-4
GO:0050884	neuromuscular process controlling posture	8.940450e-4
GO:0010985	negative regulation of lipoprotein particle clearance	8.973393e-4
GO:2000009	negative regulation of protein localization at cell surface	9.004814e-4
GO:0006683	galactosylceramide catabolic process	9.004814e-4
GO:0045769	negative regulation of asymmetric cell division	9.004814e-4
GO:0008612	peptidyl-lysine modification to hypusine	9.013430e-4
GO:0050658	RNA transport	9.101718e-4
GO:0045821	positive regulation of glycolysis	9.477842e-4
GO:0031401	positive regulation of protein modification process	9.563561e-4
GO:0060487	lung epithelial cell differentiation	9.744118e-4
GO:0030282	bone mineralization	9.744118e-4
GO:2000026	regulation of multicellular organismal development	9.765852e-4
GO:0070875	positive regulation of glycogen metabolic process	9.807558e-4
GO:0016998	cell wall macromolecule catabolic process	9.858209e-4
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	9.877701e-4
GO:0001570	vasculogenesis	9.897269e-4
GO:2000177	regulation of neural precursor cell proliferation	1.001020e-3
GO:0045844	positive regulation of striated muscle tissue development	1.012660e-3
GO:0051782	negative regulation of cell division	1.013607e-3
GO:0002036	regulation of L-glutamate transport	1.015502e-3
GO:0043587	tongue morphogenesis	1.016164e-3
GO:0034622	cellular macromolecular complex assembly	1.036101e-3
GO:0001933	negative regulation of protein phosphorylation	1.069794e-3
GO:0002344	B cell affinity maturation	1.081106e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.094897e-3
GO:0001501	skeletal system development	1.110482e-3
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	1.115998e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	1.124594e-3
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	1.124594e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.145534e-3
GO:0051253	negative regulation of RNA metabolic process	1.159925e-3
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.160815e-3
GO:0010827	regulation of glucose transport	1.168863e-3
GO:0051313	attachment of spindle microtubules to chromosome	1.175257e-3
GO:0060255	regulation of macromolecule metabolic process	1.199375e-3
GO:0007519	skeletal muscle tissue development	1.234370e-3
GO:0034621	cellular macromolecular complex subunit organization	1.269151e-3
GO:0043096	purine base salvage	1.282285e-3
GO:0002439	chronic inflammatory response to antigenic stimulus	1.285337e-3
GO:0072092	ureteric bud invasion	1.345212e-3
GO:0070836	caveola assembly	1.345228e-3
GO:0043060	meiotic metaphase I plate congression	1.345228e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	1.353939e-3
GO:0060024	rhythmic synaptic transmission	1.356288e-3
GO:0048732	gland development	1.358181e-3
GO:0051303	establishment of chromosome localization	1.368237e-3
GO:0001503	ossification	1.394521e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.427957e-3
GO:2000647	negative regulation of stem cell proliferation	1.427957e-3
GO:0071247	cellular response to chromate	1.427957e-3
GO:0010933	positive regulation of macrophage tolerance induction	1.427957e-3
GO:0070563	negative regulation of vitamin D receptor signaling pathway	1.427957e-3
GO:0010839	negative regulation of keratinocyte proliferation	1.427957e-3
GO:0035921	desmosome disassembly	1.427957e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	1.451281e-3
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.501034e-3
GO:0018202	peptidyl-histidine modification	1.524022e-3
GO:0002679	respiratory burst involved in defense response	1.524022e-3
GO:0060123	regulation of growth hormone secretion	1.535811e-3
GO:0071286	cellular response to magnesium ion	1.573476e-3
GO:2000383	regulation of ectoderm development	1.600855e-3
GO:0006177	GMP biosynthetic process	1.600855e-3
GO:0006449	regulation of translational termination	1.600855e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.601316e-3
GO:0060312	regulation of blood vessel remodeling	1.624259e-3
GO:0014816	satellite cell differentiation	1.624259e-3
GO:0071695	anatomical structure maturation	1.631138e-3
GO:0001919	regulation of receptor recycling	1.635526e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	1.672292e-3
GO:0001921	positive regulation of receptor recycling	1.672292e-3
GO:0090181	regulation of cholesterol metabolic process	1.715283e-3
GO:0042063	gliogenesis	1.730574e-3
GO:0006366	transcription from RNA polymerase II promoter	1.748731e-3
GO:0033484	nitric oxide homeostasis	1.753595e-3
GO:0008054	cyclin catabolic process	1.763327e-3
GO:0006351	transcription, DNA-dependent	1.771641e-3
GO:0048643	positive regulation of skeletal muscle tissue development	1.783878e-3
GO:0051055	negative regulation of lipid biosynthetic process	1.788279e-3
GO:0051960	regulation of nervous system development	1.791127e-3
GO:0060479	lung cell differentiation	1.822130e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	1.879467e-3
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.901730e-3
GO:0006413	translational initiation	1.903888e-3
GO:0048661	positive regulation of smooth muscle cell proliferation	1.916225e-3
GO:0051094	positive regulation of developmental process	1.948467e-3
GO:0001765	membrane raft assembly	1.977720e-3
GO:0034453	microtubule anchoring	1.980144e-3
GO:0014003	oligodendrocyte development	1.988892e-3
GO:0032774	RNA biosynthetic process	2.020745e-3
GO:0002070	epithelial cell maturation	2.028047e-3
GO:0048699	generation of neurons	2.054043e-3
GO:0045727	positive regulation of translation	2.093046e-3
GO:0022008	neurogenesis	2.095840e-3
GO:0032006	regulation of TOR signaling cascade	2.110888e-3
GO:0030177	positive regulation of Wnt receptor signaling pathway	2.118764e-3
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	2.125203e-3
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	2.147220e-3
GO:2000119	negative regulation of sodium-dependent phosphate transport	2.147220e-3
GO:0051882	mitochondrial depolarization	2.147220e-3
GO:0031860	telomeric 3' overhang formation	2.147220e-3
GO:0051657	maintenance of organelle location	2.195794e-3
GO:0060480	lung goblet cell differentiation	2.211234e-3
GO:0045964	positive regulation of dopamine metabolic process	2.211234e-3
GO:0016572	histone phosphorylation	2.221568e-3
GO:0010984	regulation of lipoprotein particle clearance	2.232674e-3
GO:0045950	negative regulation of mitotic recombination	2.249426e-3
GO:0048343	paraxial mesodermal cell fate commitment	2.249426e-3
GO:0051775	response to redox state	2.263604e-3
GO:0050717	positive regulation of interleukin-1 alpha secretion	2.263604e-3
GO:0022410	circadian sleep/wake cycle process	2.295241e-3
GO:0022403	cell cycle phase	2.321766e-3
GO:0007520	myoblast fusion	2.369273e-3
GO:0046425	regulation of JAK-STAT cascade	2.385041e-3
GO:0051340	regulation of ligase activity	2.388913e-3
GO:0006110	regulation of glycolysis	2.415579e-3
GO:0060215	primitive hemopoiesis	2.450929e-3
GO:0007051	spindle organization	2.523222e-3
GO:0060159	regulation of dopamine receptor signaling pathway	2.571608e-3
GO:0014013	regulation of gliogenesis	2.637716e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	2.637721e-3
GO:0035910	ascending aorta morphogenesis	2.637721e-3
GO:0016446	somatic hypermutation of immunoglobulin genes	2.637721e-3
GO:0071841	cellular component organization or biogenesis at cellular level	2.674861e-3
GO:0001678	cellular glucose homeostasis	2.755683e-3
GO:0021953	central nervous system neuron differentiation	2.777590e-3
GO:0008542	visual learning	2.787086e-3
GO:0060638	mesenchymal-epithelial cell signaling	2.818287e-3
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	2.843852e-3
GO:0051255	spindle midzone assembly	2.843852e-3
GO:0051899	membrane depolarization	2.887937e-3
GO:0007628	adult walking behavior	2.909342e-3
GO:0061002	negative regulation of dendritic spine morphogenesis	2.933915e-3
GO:0080125	multicellular structure septum development	2.974219e-3
GO:0070256	negative regulation of mucus secretion	2.974219e-3
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	2.974219e-3
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	2.974219e-3
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	2.974219e-3
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	2.974219e-3
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	2.974219e-3
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	2.974219e-3
GO:0007502	digestive tract mesoderm development	2.974219e-3
GO:0021526	medial motor column neuron differentiation	2.974219e-3
GO:0014858	positive regulation of skeletal muscle cell proliferation	2.974219e-3
GO:0046534	positive regulation of photoreceptor cell differentiation	2.974219e-3
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	2.974219e-3
GO:0007059	chromosome segregation	2.991310e-3
GO:0035270	endocrine system development	3.044808e-3
GO:0070373	negative regulation of ERK1 and ERK2 cascade	3.045150e-3
GO:0050679	positive regulation of epithelial cell proliferation	3.135266e-3
GO:0045685	regulation of glial cell differentiation	3.165945e-3
GO:0060525	prostate glandular acinus development	3.208915e-3
GO:0060516	primary prostatic bud elongation	3.226121e-3
GO:0072093	metanephric renal vesicle formation	3.226121e-3
GO:0032075	positive regulation of nuclease activity	3.226121e-3
GO:0046717	acid secretion	3.253370e-3
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	3.253370e-3
GO:0042053	regulation of dopamine metabolic process	3.280601e-3
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	3.292501e-3
GO:0060428	lung epithelium development	3.337500e-3
GO:0042745	circadian sleep/wake cycle	3.372308e-3
GO:0001945	lymph vessel development	3.372308e-3
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	3.416191e-3
GO:0043623	cellular protein complex assembly	3.505261e-3
GO:0021679	cerebellar molecular layer development	3.527697e-3
GO:0021750	vestibular nucleus development	3.527697e-3
GO:0021590	cerebellum maturation	3.527697e-3
GO:0010936	negative regulation of macrophage cytokine production	3.527697e-3
GO:0006548	histidine catabolic process	3.540231e-3
GO:0033345	asparagine catabolic process via L-aspartate	3.548325e-3
GO:0007060	male meiosis chromosome segregation	3.548325e-3
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	3.548325e-3
GO:0042362	fat-soluble vitamin biosynthetic process	3.551603e-3
GO:2000602	regulation of interphase of mitotic cell cycle	3.617193e-3
GO:0051896	regulation of protein kinase B signaling cascade	3.617193e-3
GO:0007442	hindgut morphogenesis	3.623559e-3
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	3.657494e-3
GO:0031400	negative regulation of protein modification process	3.700866e-3
GO:0051054	positive regulation of DNA metabolic process	3.732421e-3
GO:0060556	regulation of vitamin D biosynthetic process	3.737165e-3
GO:2000465	regulation of glycogen (starch) synthase activity	3.764513e-3
GO:0060538	skeletal muscle organ development	3.801215e-3
GO:0090187	positive regulation of pancreatic juice secretion	3.820066e-3
GO:0090340	positive regulation of secretion of lysosomal enzymes	3.820066e-3
GO:0090108	positive regulation of high-density lipoprotein particle assembly	3.820066e-3
GO:0035087	siRNA loading onto RISC involved in RNA interference	3.820066e-3
GO:0031123	RNA 3'-end processing	3.820270e-3
GO:0048814	regulation of dendrite morphogenesis	3.840645e-3
GO:0045787	positive regulation of cell cycle	3.844252e-3
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	3.855559e-3
GO:0045597	positive regulation of cell differentiation	3.868648e-3
GO:0050767	regulation of neurogenesis	3.908878e-3