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MCL coexpression mm9:153: Difference between revisions

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{{MCL_coexpression_mm9
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endopeptidase activity;6.06090620063333e-07;194597,69511,626834,69540,16624,213171,317653!GO:0017171;serine hydrolase activity;6.06090620063333e-07;194597,69511,626834,69540,16624,213171,317653!GO:0008236;serine-type peptidase activity;6.06090620063333e-07;194597,69511,626834,69540,16624,213171,317653!GO:0004175;endopeptidase activity;7.2043238836941e-05;194597,69511,626834,69540,16624,213171,317653!GO:0008233;peptidase activity;0.00116283574289886;194597,69511,626834,69540,16624,213171,317653!GO:0030057;desmosome;0.005856251769094;13512,13505!GO:0016787;hydrolase activity;0.00805534871519745;78390,626834,69540,14466,194597,69511,240633,16624,317653,213171!GO:0014704;intercalated disc;0.037203090945234;13512,13505!GO:0004348;glucosylceramidase activity;0.0406699387688814;14466!GO:0005914;spot adherens 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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0354470656487682,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.107511441879825,0,0,0,0,0,0,0,0,0,0,0.0469568706916304,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0609639314262262,0,0,0,0,0,0,0,0,0.106546909924599,0.378944271378867,0.349217833319497,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0459746052933369,0,0,0.297362109540806,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0576433181427177,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.395147443740481,0.360160685725083,0.306493592149316,0.445695280382219,0.393973009837154,0,0,0,0,0,0,0,0,0,0,0,0.587038450077457,0,0,0.187528251581031,0.822520080983509,0.824609126575683,0.612982947476269,0.474752670727528,0.643731645334388,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0417740847988257,0,0,0,0,0,1.36271726545835,0,0,0,0,0,0,1.51489982809727,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0945084131504676,0,0,0.0871588832444397,0.081359932135904,0,0,0.098117166361508,0.0750453505157095,0.0388749848471105,0.0523284672130554,0.0690411384905589,0,0.0476191773904887,0.0766073954291401,0,0.0596387295197733,0.0549933256443762,0.0709519923534245,0,0.0589368614163519,0.0748964051866952,0.0352754493378881,0.0729583017401753,0.101427320830301,0.0553034373508932,0,0.0486884105045233,0.0780974029773103,0,0.0625582350728301,0.198305064902181,0.397742527884853,0.223170651575938,0.216063761676531,0.0760168881589905,0.0865703124974023,0
|gostat_on_MCL_coexpression=GO:0004252;serine-type endopeptidase activity;6.06090620063333e-07;194597,69511,626834,69540,16624,213171,317653!GO:0017171;serine hydrolase activity;6.06090620063333e-07;194597,69511,626834,69540,16624,213171,317653!GO:0008236;serine-type peptidase activity;6.06090620063333e-07;194597,69511,626834,69540,16624,213171,317653!GO:0004175;endopeptidase activity;7.2043238836941e-05;194597,69511,626834,69540,16624,213171,317653!GO:0008233;peptidase activity;0.00116283574289886;194597,69511,626834,69540,16624,213171,317653!GO:0030057;desmosome;0.005856251769094;13512,13505!GO:0016787;hydrolase activity;0.00805534871519745;78390,626834,69540,14466,194597,69511,240633,16624,317653,213171!GO:0014704;intercalated disc;0.037203090945234;13512,13505!GO:0004348;glucosylceramidase activity;0.0406699387688814;14466!GO:0005914;spot adherens junction;0.0406699387688814;13512!
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000014!4.51e-10!5;UBERON:0001003!4.51e-10!5;UBERON:0002097!4.51e-10!5;UBERON:0002199!4.51e-10!5;UBERON:0007029!4.51e-10!5;UBERON:0007376!4.51e-10!5;UBERON:0002416!4.51e-10!5;UBERON:0007383!4.51e-10!5;UBERON:0003102!3.50e-07!22
|tfbs_overrepresentation_for_novel_motifs=0.157908,0.0643756,0.053304,0.389804,0.229133,0.948931,0.0871309,0.652787,0.406888,0.0175496,0.165495,0.0798412,0.101363,0.021755,0.415291,0,0.264932,0.870162,1.58336,0.425335,0.903679,0.247601,0.0215906,0.132505,0.25242,0.274691,0.367972,0.280989,0.222911,0.766408,0.00853337,0.771283,0.204237,0.380937,0.0143704,3.7975,0.00162569,0.199324,0.0759931,1.0608,0.68012,0.0460424,0.421855,0.422858,0.170647,0.0317889,0.184444,0.0572602,1.76731,0.541466,0.0700706,0.0332027,0.554408,0.200094,0.21096,0.0996603,0.57957,0.0725085,1.5972,0.098299,0.359721,0.141614,1.51386,0.505326,0.0252596,0.277917,0.303342,0.584739,0.717812,0.459985,0.0428777,1.59352,0.00142923,0.232491,0.00120846,0.458373,2.5451,0.174085,0.103709,0.305175,2.19387,0.284198,0.035146,0.00996845,0.162119,0.00155764,0.00159628,3.64517,1.13512,0.729455,0.934866,0.164931,0.401354,1.51356,0.00412757,0.902048,0.24298,0.404995,0.0492032,0.566904,1.27705,0.121192,0.189476,0.527937,0.245677,0.00899714,0.0938788,0.302661,0.0942811,0.0350968,0.0206992,0.190551,0.308077,0.171441,0.360432,1.12912,0.0547641,0.106832,0.266356,0.768984,0.236036,0.213175,0.821975,0.39136,0.402541,0.105399,0.438231,0.124312,0.302247,0.754631,0.179365,0.586308,0.281191,0.109035,0.377064,0.313368,2.09891,0.711245,0.900453,1.07546,0.700549,3.16026,0.124054,0.398336,0.0675277,7.49439,0.418028,1.03741,0.506563,0.0721206,0.791749,2.36579e-06,0.201062,0.0273578,0.108385,0.25399,0.316862,0.87434,0.28615,0.0247496,0.346709,0.486744,1.1557,0.145578,0.507258,0.25307,1.54761,0.391236,0.0112813
|tfbs_overrepresentation_jaspar=MA0003.1;0.000193144,MA0004.1;0.221104,MA0006.1;0.0831859,MA0007.1;1.84862,MA0009.1;0.13467,MA0014.1;0.000506206,MA0017.1;0.208737,MA0019.1;0.457336,MA0024.1;0.11295,MA0025.1;0.278029,MA0027.1;1.56266,MA0028.1;0.0157618,MA0029.1;0.102863,MA0030.1;0.344385,MA0031.1;0.0901414,MA0038.1;0.274576,MA0040.1;0.141215,MA0041.1;0.0148578,MA0042.1;0.199482,MA0043.1;0.188871,MA0046.1;0.153843,MA0048.1;0.177827,MA0050.1;0.010381,MA0051.1;0.029068,MA0052.1;0.145506,MA0055.1;0.265839,MA0056.1;0,MA0057.1;0.0552795,MA0058.1;0.319876,MA0059.1;0.209507,MA0060.1;0.00234797,MA0061.1;0.143884,MA0063.1;0,MA0066.1;0.484688,MA0067.1;0.359458,MA0068.1;0.0993399,MA0069.1;0.145688,MA0070.1;0.14053,MA0071.1;0.286377,MA0072.1;0.835975,MA0073.1;0.753658,MA0074.1;0.665132,MA0076.1;0.00734103,MA0077.1;0.125051,MA0078.1;1.3712,MA0081.1;0.254334,MA0083.1;0.552043,MA0084.1;0.632114,MA0087.1;0.490752,MA0088.1;2.19256,MA0089.1;0,MA0090.1;0.310023,MA0091.1;0.242763,MA0092.1;1.01741,MA0093.1;0.192438,MA0095.1;0,MA0098.1;0,MA0100.1;0.0759853,MA0101.1;0.118095,MA0103.1;1.60249,MA0105.1;0.355788,MA0106.1;3.61582,MA0107.1;0.121702,MA0108.2;0.499602,MA0109.1;0,MA0111.1;0.342453,MA0113.1;0.031917,MA0114.1;0.0149307,MA0115.1;0.190558,MA0116.1;0.156119,MA0117.1;0.171502,MA0119.1;0.118772,MA0122.1;0.539295,MA0124.1;0.319566,MA0125.1;0.266765,MA0130.1;0,MA0131.1;0.0555822,MA0132.1;0,MA0133.1;0,MA0135.1;0.211304,MA0136.1;0.727662,MA0139.1;0.0253888,MA0140.1;0.19543,MA0141.1;0.160107,MA0142.1;0.285564,MA0143.1;0.142797,MA0144.1;0.502869,MA0145.1;0.0851549,MA0146.1;0.016865,MA0147.1;0.096871,MA0148.1;0.432296,MA0149.1;72.8519,MA0062.2;0.0010827,MA0035.2;0.0786412,MA0039.2;0.736523,MA0138.2;0.0530361,MA0002.2;0.489317,MA0137.2;0.155511,MA0104.2;0.0367282,MA0047.2;0.273458,MA0112.2;1.94355,MA0065.2;0.661548,MA0150.1;2.26879,MA0151.1;0,MA0152.1;0.113299,MA0153.1;0.221887,MA0154.1;0.329009,MA0155.1;0.185361,MA0156.1;0.578624,MA0157.1;0.0715576,MA0158.1;0,MA0159.1;0.446532,MA0160.1;0.440143,MA0161.1;0,MA0162.1;4.18667e-05,MA0163.1;0.000331013,MA0164.1;1.07003,MA0080.2;1.24838,MA0018.2;0.25038,MA0099.2;1.14042,MA0079.2;0.0894283,MA0102.2;0.678885,MA0258.1;1.21329,MA0259.1;0.0828026,MA0442.1;0
}}

Latest revision as of 14:47, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:60945020..60945033,+p@chr10:60945020..60945033
+
Mm9::chr10:78059309..78059314,+p@chr10:78059309..78059314
+
Mm9::chr11:121381087..121381108,-p4@Zfp750
Mm9::chr11:121381115..121381124,-p5@Zfp750
Mm9::chr11:60744645..60744669,+p@chr11:60744645..60744669
+
Mm9::chr11:76015586..76015605,+p1@Fam57a
Mm9::chr11:76029840..76029844,+p@chr11:76029840..76029844
+
Mm9::chr11:94359484..94359505,-p3@Epn3
Mm9::chr11:94359507..94359521,-p4@Epn3
Mm9::chr11:99978945..99978960,-p@chr11:99978945..99978960
-
Mm9::chr11:99980388..99980398,+p@chr11:99980388..99980398
+
Mm9::chr12:105251850..105251868,-p1@Serpina9
Mm9::chr12:25257486..25257498,+p@chr12:25257486..25257498
+
Mm9::chr13:3803553..3803583,-p1@Calml3
Mm9::chr13:51851974..51852005,-p5@Sema4d
Mm9::chr13:56107389..56107398,+p@chr13:56107389..56107398
+
Mm9::chr15:101784707..101784725,-p1@Krt78
p1@LOC100505154
Mm9::chr15:74558441..74558460,-p1@Slurp1
Mm9::chr17:24175190..24175195,+p2@Prss27
Mm9::chr17:31827369..31827371,-p@chr17:31827369..31827371
-
Mm9::chr17:35704410..35704435,+p2@2300002M23Rik
Mm9::chr17:35704472..35704489,+p1@2300002M23Rik
Mm9::chr18:20273411..20273416,-p10@Dsc1
Mm9::chr18:20668724..20668735,+p3@Dsg3
Mm9::chr18:20668754..20668768,+p1@Dsg3
Mm9::chr18:20668770..20668791,+p2@Dsg3
Mm9::chr18:20668792..20668802,+p4@Dsg3
Mm9::chr19:34082737..34082759,+p2@Lipk
Mm9::chr1:109258883..109258896,+p1@Serpinb11
Mm9::chr1:133647062..133647071,+p3@Slc26a9
Mm9::chr1:133647083..133647096,+p2@Slc26a9
Mm9::chr1:174488278..174488293,-p2@ENSMUST00000169111
Mm9::chr2:120114799..120114810,-p1@Pla2g4d
Mm9::chr2:120911571..120911582,-p3@Tgm5
Mm9::chr2:122139450..122139472,-p1@Duoxa1
Mm9::chr2:122139525..122139542,+p@chr2:122139525..122139542
+
Mm9::chr2:122139562..122139571,+p@chr2:122139562..122139571
+
Mm9::chr2:24070988..24070994,+p1@Il1f6
Mm9::chr3:122788591..122788596,+p@chr3:122788591..122788596
+
Mm9::chr3:89006916..89006932,+p3@Gba
Mm9::chr3:90458175..90458201,+p2@S100a7a
Mm9::chr3:92336882..92336894,-p@chr3:92336882..92336894
-
Mm9::chr3:92336900..92336911,-p@chr3:92336900..92336911
-
Mm9::chr3:92730164..92730169,-p1@Lce3a
Mm9::chr3:92736897..92736905,+p1@Lce3b
Mm9::chr3:92748405..92748409,+p1@Lce3c
Mm9::chr3:92770981..92770984,+p2@2310001H18Rik
Mm9::chr3:92796135..92796143,+p1@2310001H18Rik
p1@LOC630971
p1@Lce3f
Mm9::chr4:132807438..132807463,+p@chr4:132807438..132807463
+
Mm9::chr5:144137380..144137416,-p@chr5:144137380..144137416
-
Mm9::chr5:32452460..32452499,+p@chr5:32452460..32452499
+
Mm9::chr5:86898097..86898148,-p1@Tmprss11a
Mm9::chr5:86898159..86898166,-p2@Tmprss11a
Mm9::chr6:128958807..128958818,+p@chr6:128958807..128958818
+
Mm9::chr6:135269573..135269585,-p1@uc009eln.1
Mm9::chr7:50718478..50718483,+p4@Vsig10l
Mm9::chr7:50718515..50718555,+p1@Vsig10l
Mm9::chr7:50718557..50718585,+p2@Vsig10l
Mm9::chr7:50718589..50718596,+p3@Vsig10l
Mm9::chr7:50945518..50945536,+p1@Klk14
Mm9::chr7:50950366..50950405,+p@chr7:50950366..50950405
+
Mm9::chr7:50950415..50950438,+p@chr7:50950415..50950438
+
Mm9::chr7:50950453..50950481,+p@chr7:50950453..50950481
+
Mm9::chr7:50968557..50968564,+p@chr7:50968557..50968564
+
Mm9::chr7:50968796..50968806,+p@chr7:50968796..50968806
+
Mm9::chr7:50982467..50982472,+p@chr7:50982467..50982472
+
Mm9::chr7:51024283..51024314,+p1@Klk12
Mm9::chr7:51024319..51024331,+p2@Klk12
Mm9::chr7:51036429..51036448,+p1@Klk10
Mm9::chr7:51052937..51052956,+p2@Klk8
Mm9::chr8:19194319..19194333,+p1@Defb14
Mm9::chr8:83385000..83385018,-p@chr8:83385000..83385018
-
Mm9::chr9:98386529..98386544,+p@chr9:98386529..98386544
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004252serine-type endopeptidase activity6.06090620063333e-07
GO:0017171serine hydrolase activity6.06090620063333e-07
GO:0008236serine-type peptidase activity6.06090620063333e-07
GO:0004175endopeptidase activity7.2043238836941e-05
GO:0008233peptidase activity0.00116283574289886
GO:0030057desmosome0.005856251769094
GO:0016787hydrolase activity0.00805534871519745
GO:0014704intercalated disc0.037203090945234
GO:0004348glucosylceramidase activity0.0406699387688814
GO:0005914spot adherens junction0.0406699387688814



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
zone of skin4.51e-105
skin epidermis4.51e-105
skin of body4.51e-105
integument4.51e-105
surface4.51e-105
outer epithelium4.51e-105
integumental system4.51e-105
enveloping layer of ectoderm4.51e-105
surface structure3.50e-0722


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.000193144
MA0004.10.221104
MA0006.10.0831859
MA0007.11.84862
MA0009.10.13467
MA0014.10.000506206
MA0017.10.208737
MA0019.10.457336
MA0024.10.11295
MA0025.10.278029
MA0027.11.56266
MA0028.10.0157618
MA0029.10.102863
MA0030.10.344385
MA0031.10.0901414
MA0038.10.274576
MA0040.10.141215
MA0041.10.0148578
MA0042.10.199482
MA0043.10.188871
MA0046.10.153843
MA0048.10.177827
MA0050.10.010381
MA0051.10.029068
MA0052.10.145506
MA0055.10.265839
MA0056.10
MA0057.10.0552795
MA0058.10.319876
MA0059.10.209507
MA0060.10.00234797
MA0061.10.143884
MA0063.10
MA0066.10.484688
MA0067.10.359458
MA0068.10.0993399
MA0069.10.145688
MA0070.10.14053
MA0071.10.286377
MA0072.10.835975
MA0073.10.753658
MA0074.10.665132
MA0076.10.00734103
MA0077.10.125051
MA0078.11.3712
MA0081.10.254334
MA0083.10.552043
MA0084.10.632114
MA0087.10.490752
MA0088.12.19256
MA0089.10
MA0090.10.310023
MA0091.10.242763
MA0092.11.01741
MA0093.10.192438
MA0095.10
MA0098.10
MA0100.10.0759853
MA0101.10.118095
MA0103.11.60249
MA0105.10.355788
MA0106.13.61582
MA0107.10.121702
MA0108.20.499602
MA0109.10
MA0111.10.342453
MA0113.10.031917
MA0114.10.0149307
MA0115.10.190558
MA0116.10.156119
MA0117.10.171502
MA0119.10.118772
MA0122.10.539295
MA0124.10.319566
MA0125.10.266765
MA0130.10
MA0131.10.0555822
MA0132.10
MA0133.10
MA0135.10.211304
MA0136.10.727662
MA0139.10.0253888
MA0140.10.19543
MA0141.10.160107
MA0142.10.285564
MA0143.10.142797
MA0144.10.502869
MA0145.10.0851549
MA0146.10.016865
MA0147.10.096871
MA0148.10.432296
MA0149.172.8519
MA0062.20.0010827
MA0035.20.0786412
MA0039.20.736523
MA0138.20.0530361
MA0002.20.489317
MA0137.20.155511
MA0104.20.0367282
MA0047.20.273458
MA0112.21.94355
MA0065.20.661548
MA0150.12.26879
MA0151.10
MA0152.10.113299
MA0153.10.221887
MA0154.10.329009
MA0155.10.185361
MA0156.10.578624
MA0157.10.0715576
MA0158.10
MA0159.10.446532
MA0160.10.440143
MA0161.10
MA0162.14.18667e-05
MA0163.10.000331013
MA0164.11.07003
MA0080.21.24838
MA0018.20.25038
MA0099.21.14042
MA0079.20.0894283
MA0102.20.678885
MA0258.11.21329
MA0259.10.0828026
MA0442.10
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