UBERON:0000029: Difference between revisions
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|located_in= | |located_in= | ||
|name=lymph node | |name=lymph node | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of=UBERON:0002465 | |part_of=UBERON:0002465 | ||
Latest revision as of 17:04, 12 September 2014
| Name: | lymph node | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "Oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system. Lymph nodes are garrisons of B, T, and other immune cells. Lymph nodes are found all through the body, and act as filters or traps for foreign particles. They contain white blood cells that use oxygen to process. Thus they are important in the proper functioning of the immune system. The lymph node is surrounded by a fibrous capsule, and inside the lymph node the fibrous capsule extends to form trabeculae. The substance of the lymph node is divided into the outer cortex and the inner medulla surrounded by the former all around except for at the hilum, where the medulla comes in direct contact with the surface. Thin reticular fibers, elastin and reticular fibers form a supporting meshwork called reticular network (RN) inside the node, within which the white blood cells (WBCs), most prominently, lymphocytes are tightly packed as follicles in the cortex. Elsewhere, there are only occasional WBCs. The RN provides not just the structural support, but also provide surface for adhesion of the dendritic cells, macrophages and lymphocytes. It allows for exchange of material with blood through the high endothelial venules and provides the growth and regulatory factors necessary for activation and maturation of immune cells[WP]." [GAID:947, Wikipedia:Lymph_node] | ||
| Xrefs: |
| ||
| Synonyms: | "nodus lymphaticus" RELATED LATIN [Wikipedia:Lymph_node] | ||
| Subset: |
uberon_slim vertebrate_core |
Illu_lymph_node_structure.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0005057(immune organ) |
|---|---|
| part_of: | UBERON:0002465(lymphoid system) |
Children
| is a: | UBERON:0003968 (peripheral lymph node) |
|---|---|
| derives from: | FF:0010077 (human lymph node - adult sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10077-102A5 (lymph node, adult, donor1)
- 1063-29H9 (accessory axillary lymph node, adult)
Mouse (Mus musculus)
- 10077-102A5 (lymph node, adult, donor1)
- 1063-29H9 (accessory axillary lymph node, adult)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000029 (lymph node), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 3.07e-86 | FFCP PHASE1:Mm9::chr16:19235714..19235723,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr16:19235714..19235723, - |
| 3.07e-86 | FFCP PHASE1:Mm9::chr15:98457062..98457072,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr15:98457062..98457072, + |
| 3.07e-86 | FFCP PHASE1:Mm9::chr12:104978425..104978430,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr12:104978425..104978430, - |
| 3.07e-86 | FFCP PHASE2:Mm9::chr16:19235714..19235723,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr16:19235714..19235723, - |
| 3.07e-86 | FFCP PHASE2:Mm9::chr10:73409774..73409819,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr10:73409774..73409819, + |
| 3.07e-86 | FFCP PHASE2:Mm9::chr8:3918216..3918219,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr8:3918216..3918219, - |
| 3.07e-86 | FFCP PHASE1:Mm9::chr10:73409774..73409819,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr10:73409774..73409819, + |
| 3.07e-86 | FFCP PHASE2:Mm9::chr12:93042811..93042816,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr12:93042811..93042816, - |
| 3.07e-86 | FFCP PHASE2:Mm9::chr12:104978425..104978430,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr12:104978425..104978430, - |
| 3.07e-86 | FFCP PHASE2:Mm9::chr11:5405967..5405985,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr11:5405967..5405985, + |
| 3.07e-86 | FFCP PHASE1:Mm9::chr15:98457111..98457118,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr15:98457111..98457118, + |
| 3.07e-86 | FFCP PHASE1:Mm9::chr12:114567506..114567507,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr12:114567506..114567507, - |
| 3.07e-86 | FFCP PHASE1:Mm9::chr4:32325858..32325865,+#_9fc0d38988654f20bcd3d8b238a70250 | p18@Bach2 |
| 3.07e-86 | FFCP PHASE2:Mm9::chr4:32325858..32325865,+#_9fc0d38988654f20bcd3d8b238a70250 | p18@Bach2 |
| 3.07e-86 | FFCP PHASE1:Mm9::chr12:93042811..93042816,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr12:93042811..93042816, - |
| 3.07e-86 | FFCP PHASE2:Mm9::chr15:98457062..98457072,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr15:98457062..98457072, + |
| 3.07e-86 | FFCP PHASE1:Mm9::chr8:3918216..3918219,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr8:3918216..3918219, - |
| 3.07e-86 | FFCP PHASE1:Mm9::chr4:122604700..122604706,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr4:122604700..122604706, - |
| 3.07e-86 | FFCP PHASE1:Mm9::chr17:37383896..37383899,+#_9fc0d38988654f20bcd3d8b238a70250 | p2@ENSMUST00000172477 |
| 3.07e-86 | FFCP PHASE1:Mm9::chr11:5405967..5405985,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr11:5405967..5405985, + |
| 3.07e-86 | FFCP PHASE2:Mm9::chr4:122604700..122604706,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr4:122604700..122604706, - |
| 3.07e-86 | FFCP PHASE2:Mm9::chr17:37383896..37383899,+#_9fc0d38988654f20bcd3d8b238a70250 | p2@ENSMUST00000172477 |
| 3.07e-86 | FFCP PHASE2:Mm9::chr15:98457111..98457118,+#_9fc0d38988654f20bcd3d8b238a70250 | p@chr15:98457111..98457118, + |
| 3.07e-86 | FFCP PHASE2:Mm9::chr12:114567506..114567507,-#_9fc0d38988654f20bcd3d8b238a70250 | p@chr12:114567506..114567507, - |
| 2.39e-66 | FFCP PHASE1:Hg19::chr5:99385820..99385831,-#_4f60b1b271c4a1c975e9f2d38c9fdcf9 | p@chr5:99385820..99385831, - |
| 2.39e-66 | FFCP PHASE2:Hg19::chr5:99385820..99385831,-#_4f60b1b271c4a1c975e9f2d38c9fdcf9 | p@chr5:99385820..99385831, - |
| 4.66e-66 | FFCP PHASE2:Hg19::chr4:146461014..146461025,+#_fb6569494edf7e83993220d56a3bc320 | p@chr4:146461014..146461025, + |
| 4.66e-66 | FFCP PHASE1:Hg19::chr4:146461014..146461025,+#_fb6569494edf7e83993220d56a3bc320 | p@chr4:146461014..146461025, + |
| 1.46e-50 | FFCP PHASE1:Hg19::chr20:3687858..3687862,-#_efdd99588b88a5759232c1dd715ba866 | p1@SIGLEC1 |
| 1.46e-50 | FFCP PHASE1:Hg19::chr14:107034971..107034980,-#_efdd99588b88a5759232c1dd715ba866 | p1@AM279543, p1@AY577299, p1@FJ385326, p1@GQ232913, p1@GQ232958, p1@GU552732, p1@GU552750, p1@S73611, p1@S73613 |
| 1.46e-50 | FFCP PHASE2:Hg19::chr20:3687858..3687862,-#_efdd99588b88a5759232c1dd715ba866 | p1@SIGLEC1 |
| 1.46e-50 | FFCP PHASE2:Hg19::chr14:107034971..107034980,-#_efdd99588b88a5759232c1dd715ba866 | p1@AM279543, p1@AY577299, p1@FJ385326, p1@GQ232913, p1@GQ232958, p1@GU552732, p1@GU552750, p1@S73611, p1@S73613 |
| 2.42e-50 | FFCP PHASE1:Hg19::chr2:68582248..68582253,-#_14f2586ac5c89fb5e4b7137ce7694b86 | p@chr2:68582248..68582253, - |
| 2.42e-50 | FFCP PHASE2:Hg19::chr14:106237005..106237028,+#_14f2586ac5c89fb5e4b7137ce7694b86 | p@chr14:106237005..106237028, + |
| 2.42e-50 | FFCP PHASE2:Hg19::chr2:68582248..68582253,-#_14f2586ac5c89fb5e4b7137ce7694b86 | p@chr2:68582248..68582253, - |
| 2.42e-50 | FFCP PHASE1:Hg19::chr14:106237005..106237028,+#_14f2586ac5c89fb5e4b7137ce7694b86 | p@chr14:106237005..106237028, + |
| 3.99e-50 | FFCP PHASE2:Hg19::chr14:106091539..106091550,-#_d9f588e777a059f01e98519a4ad5da5c | p@chr14:106091539..106091550, - |
| 3.99e-50 | FFCP PHASE1:Hg19::chr12:57038878..57038884,-#_d9f588e777a059f01e98519a4ad5da5c | p1@SNORD59A |
| 3.99e-50 | FFCP PHASE2:Hg19::chr12:57038878..57038884,-#_d9f588e777a059f01e98519a4ad5da5c | p1@SNORD59A |
| 3.99e-50 | FFCP PHASE1:Hg19::chr14:106091539..106091550,-#_d9f588e777a059f01e98519a4ad5da5c | p@chr14:106091539..106091550, - |
| 6.58e-50 | FFCP PHASE1:Hg19::chr1:22974264..22974270,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr1:22974264..22974270, + |
| 6.58e-50 | FFCP PHASE1:Hg19::chr2:103043089..103043100,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr2:103043089..103043100, + |
| 6.58e-50 | FFCP PHASE2:Hg19::chr18:514455..514467,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr18:514455..514467, + |
| 6.58e-50 | FFCP PHASE1:Hg19::chr14:106725293..106725299,-#_a90cc1ca10b272b63226d43f0f624583 | p1@AF460806, p1@DQ523922 |
| 6.58e-50 | FFCP PHASE1:Hg19::chr1:40847015..40847027,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr1:40847015..40847027, + |
| 6.58e-50 | FFCP PHASE2:Hg19::chr1:22974264..22974270,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr1:22974264..22974270, + |
| 6.58e-50 | FFCP PHASE2:Hg19::chr2:103043089..103043100,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr2:103043089..103043100, + |
| 6.58e-50 | FFCP PHASE1:Hg19::chr18:514455..514467,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr18:514455..514467, + |
| 6.58e-50 | FFCP PHASE2:Hg19::chr14:106725293..106725299,-#_a90cc1ca10b272b63226d43f0f624583 | p1@AF460806, p1@DQ523922 |
| 6.58e-50 | FFCP PHASE2:Hg19::chr1:40847015..40847027,+#_a90cc1ca10b272b63226d43f0f624583 | p@chr1:40847015..40847027, + |
| 2.74e-44 | FFCP PHASE2:Mm9::chr6:129628862..129628871,-#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr6:129628862..129628871, - |
| 2.74e-44 | FFCP PHASE2:Mm9::chr4:130488147..130488154,+#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr4:130488147..130488154, + |
| 2.74e-44 | FFCP PHASE2:Mm9::chr6:127022920..127022928,+#_24cb5bc3ebc4e6cf97687e83968266cc | p1@Fgf23 |
| 2.74e-44 | FFCP PHASE1:Mm9::chr6:129628862..129628871,-#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr6:129628862..129628871, - |
| 2.74e-44 | FFCP PHASE1:Mm9::chr3:87316559..87316571,-#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr3:87316559..87316571, - |
| 2.74e-44 | FFCP PHASE2:Mm9::chr1:156901987..156901994,-#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr1:156901987..156901994, - |
| 2.74e-44 | FFCP PHASE2:Mm9::chr15:100610674..100610678,+#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr15:100610674..100610678, + |
| 2.74e-44 | FFCP PHASE2:Mm9::chr2:152582794..152582807,+#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr2:152582794..152582807, + |
| 2.74e-44 | FFCP PHASE1:Mm9::chr2:152582794..152582807,+#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr2:152582794..152582807, + |
| 2.74e-44 | FFCP PHASE1:Mm9::chr6:127022920..127022928,+#_24cb5bc3ebc4e6cf97687e83968266cc | p1@Fgf23 |
| 2.74e-44 | FFCP PHASE1:Mm9::chr4:130488147..130488154,+#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr4:130488147..130488154, + |
| 2.74e-44 | FFCP PHASE1:Mm9::chr1:156901987..156901994,-#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr1:156901987..156901994, - |
| 2.74e-44 | FFCP PHASE2:Mm9::chr3:87316559..87316571,-#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr3:87316559..87316571, - |
| 2.74e-44 | FFCP PHASE1:Mm9::chr15:100610674..100610678,+#_24cb5bc3ebc4e6cf97687e83968266cc | p@chr15:100610674..100610678, + |
| 7.47e-44 | FFCP PHASE2:Mm9::chr5:111607677..111607689,-#_e64ead76e727cf365aabca81eaca0cca | p@chr5:111607677..111607689, - |
| 7.47e-44 | FFCP PHASE1:Mm9::chr17:73460572..73460579,+#_e64ead76e727cf365aabca81eaca0cca | p@chr17:73460572..73460579, + |
| 7.47e-44 | FFCP PHASE1:Mm9::chr2:26524291..26524300,-#_e64ead76e727cf365aabca81eaca0cca | p@chr2:26524291..26524300, - |
| 7.47e-44 | FFCP PHASE2:Mm9::chr13:83714297..83714301,+#_e64ead76e727cf365aabca81eaca0cca | p@chr13:83714297..83714301, + |
| 7.47e-44 | FFCP PHASE2:Mm9::chr1:156901880..156901891,-#_e64ead76e727cf365aabca81eaca0cca | p@chr1:156901880..156901891, - |
| 7.47e-44 | FFCP PHASE1:Mm9::chr2:70769189..70769223,+#_e64ead76e727cf365aabca81eaca0cca | p@chr2:70769189..70769223, + |
| 7.47e-44 | FFCP PHASE2:Mm9::chr8:22042143..22042150,-#_e64ead76e727cf365aabca81eaca0cca | p1@Gm15056, p1@LOC100504014 |
| 7.47e-44 | FFCP PHASE2:Mm9::chr1:69594451..69594464,-#_e64ead76e727cf365aabca81eaca0cca | p@chr1:69594451..69594464, - |
| 7.47e-44 | FFCP PHASE1:Mm9::chr17:73506745..73506750,+#_e64ead76e727cf365aabca81eaca0cca | p@chr17:73506745..73506750, + |
| 7.47e-44 | FFCP PHASE1:Mm9::chr1:69594451..69594464,-#_e64ead76e727cf365aabca81eaca0cca | p@chr1:69594451..69594464, - |
| 7.47e-44 | FFCP PHASE2:Mm9::chr17:73506745..73506750,+#_e64ead76e727cf365aabca81eaca0cca | p@chr17:73506745..73506750, + |
| 7.47e-44 | FFCP PHASE2:Mm9::chrX:13200511..13200521,+#_e64ead76e727cf365aabca81eaca0cca | p@chrX:13200511..13200521, + |
| 7.47e-44 | FFCP PHASE1:Mm9::chr5:111607677..111607689,-#_e64ead76e727cf365aabca81eaca0cca | p@chr5:111607677..111607689, - |
| 7.47e-44 | FFCP PHASE1:Mm9::chr1:156901880..156901891,-#_e64ead76e727cf365aabca81eaca0cca | p@chr1:156901880..156901891, - |
| 7.47e-44 | FFCP PHASE1:Mm9::chr8:22042143..22042150,-#_e64ead76e727cf365aabca81eaca0cca | p1@Gm15056, p1@LOC100504014 |
| 7.47e-44 | FFCP PHASE1:Mm9::chrX:7157626..7157635,+#_e64ead76e727cf365aabca81eaca0cca | p3@Foxp3 |
| 7.47e-44 | FFCP PHASE2:Mm9::chr2:70769189..70769223,+#_e64ead76e727cf365aabca81eaca0cca | p@chr2:70769189..70769223, + |
| 7.47e-44 | FFCP PHASE2:Mm9::chrX:7157626..7157635,+#_e64ead76e727cf365aabca81eaca0cca | p3@Foxp3 |
| 7.47e-44 | FFCP PHASE1:Mm9::chr13:83714297..83714301,+#_e64ead76e727cf365aabca81eaca0cca | p@chr13:83714297..83714301, + |
| 7.47e-44 | FFCP PHASE2:Mm9::chr17:73460572..73460579,+#_e64ead76e727cf365aabca81eaca0cca | p@chr17:73460572..73460579, + |
| 7.47e-44 | FFCP PHASE1:Mm9::chrX:13200511..13200521,+#_e64ead76e727cf365aabca81eaca0cca | p@chrX:13200511..13200521, + |
| 7.47e-44 | FFCP PHASE2:Mm9::chr2:26524291..26524300,-#_e64ead76e727cf365aabca81eaca0cca | p@chr2:26524291..26524300, - |
| 1.48e-40 | FFCP PHASE2:Hg19::chr4:109000758..109000770,-#_51069257db7e761178c4295cd3423846 | p49@LEF1 |
| 1.48e-40 | FFCP PHASE2:Hg19::chr14:106321813..106321821,+#_51069257db7e761178c4295cd3423846 | p5@AY671148, p5@AY671772, p5@AY671782, p5@AY671783 |
| 1.48e-40 | FFCP PHASE1:Hg19::chr4:109000758..109000770,-#_51069257db7e761178c4295cd3423846 | p49@LEF1 |
| 1.48e-40 | FFCP PHASE1:Hg19::chr14:106321813..106321821,+#_51069257db7e761178c4295cd3423846 | p5@AY671148, p5@AY671772, p5@AY671782, p5@AY671783 |
| 2.21e-40 | FFCP PHASE2:Hg19::chr17:6983503..6983512,-#_ccac7fdf41f11a5289a9d2eda43c1bb1 | p5@CLEC10A |
| 2.21e-40 | FFCP PHASE1:Hg19::chr15:31685082..31685093,+#_ccac7fdf41f11a5289a9d2eda43c1bb1 | p40@KLF13 |
| 2.21e-40 | FFCP PHASE1:Hg19::chr6:109669625..109669629,+#_ccac7fdf41f11a5289a9d2eda43c1bb1 | p@chr6:109669625..109669629, + |
| 2.21e-40 | FFCP PHASE1:Hg19::chr17:6983503..6983512,-#_ccac7fdf41f11a5289a9d2eda43c1bb1 | p5@CLEC10A |
| 2.21e-40 | FFCP PHASE2:Hg19::chr15:31685082..31685093,+#_ccac7fdf41f11a5289a9d2eda43c1bb1 | p40@KLF13 |
| 2.21e-40 | FFCP PHASE2:Hg19::chr6:109669625..109669629,+#_ccac7fdf41f11a5289a9d2eda43c1bb1 | p@chr6:109669625..109669629, + |
| 2.58e-34 | FFCP PHASE1:Hg19::chr2:207082631..207082640,-#_94a97a7ce0533e4ed712be682d9cd2e0 | p7@GPR1 |
| 2.58e-34 | FFCP PHASE1:Hg19::chr2:28824788..28824791,+#_94a97a7ce0533e4ed712be682d9cd2e0 | p7@PLB1 |
| 2.58e-34 | FFCP PHASE2:Hg19::chr2:207082631..207082640,-#_94a97a7ce0533e4ed712be682d9cd2e0 | p7@GPR1 |
| 2.58e-34 | FFCP PHASE2:Hg19::chr2:28824788..28824791,+#_94a97a7ce0533e4ed712be682d9cd2e0 | p7@PLB1 |
