MCL coexpression mm9:74
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0015103 | inorganic anion transmembrane transporter activity | 0.00514924822035792 |
| GO:0005506 | iron ion binding | 0.00514924822035792 |
| GO:0050381 | unspecific monooxygenase activity | 0.00514924822035792 |
| GO:0004035 | alkaline phosphatase activity | 0.00521089416858834 |
| GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | 0.00521089416858834 |
| GO:0022891 | substrate-specific transmembrane transporter activity | 0.00523803575981668 |
| GO:0004497 | monooxygenase activity | 0.00680743923071851 |
| GO:0015380 | anion exchanger activity | 0.00712892953292769 |
| GO:0005542 | folic acid binding | 0.00712892953292769 |
| GO:0022857 | transmembrane transporter activity | 0.00712892953292769 |
| GO:0015106 | bicarbonate transmembrane transporter activity | 0.00712892953292769 |
| GO:0015301 | anion:anion antiporter activity | 0.00712892953292769 |
| GO:0000041 | transition metal ion transport | 0.00712892953292769 |
| GO:0005792 | microsome | 0.00721642251051719 |
| GO:0015108 | chloride transmembrane transporter activity | 0.00721642251051719 |
| GO:0042598 | vesicular fraction | 0.00721642251051719 |
| GO:0006812 | cation transport | 0.00721642251051719 |
| GO:0006810 | transport | 0.00721642251051719 |
| GO:0022892 | substrate-specific transporter activity | 0.00791433396164989 |
| GO:0051234 | establishment of localization | 0.00791433396164989 |
| GO:0022804 | active transmembrane transporter activity | 0.00791433396164989 |
| GO:0006811 | ion transport | 0.00791433396164989 |
| GO:0015291 | secondary active transmembrane transporter activity | 0.00791433396164989 |
| GO:0016491 | oxidoreductase activity | 0.0124565273912681 |
| GO:0051179 | localization | 0.0124565273912681 |
| GO:0031975 | envelope | 0.0141690086600273 |
| GO:0031967 | organelle envelope | 0.0141690086600273 |
| GO:0030001 | metal ion transport | 0.016093860951146 |
| GO:0005743 | mitochondrial inner membrane | 0.0167995100044327 |
| GO:0019866 | organelle inner membrane | 0.0185470801125522 |
| GO:0006826 | iron ion transport | 0.0185470801125522 |
| GO:0015075 | ion transmembrane transporter activity | 0.0186670961025181 |
| GO:0046872 | metal ion binding | 0.0186670961025181 |
| GO:0008509 | anion transmembrane transporter activity | 0.0186670961025181 |
| GO:0031966 | mitochondrial membrane | 0.0186670961025181 |
| GO:0005624 | membrane fraction | 0.0193196957794729 |
| GO:0043167 | ion binding | 0.0193196957794729 |
| GO:0015886 | heme transport | 0.0193196957794729 |
| GO:0015499 | formate transmembrane transporter activity | 0.0193196957794729 |
| GO:0015851 | nucleobase transport | 0.0193196957794729 |
| GO:0015724 | formate transport | 0.0193196957794729 |
| GO:0015232 | heme transporter activity | 0.0193196957794729 |
| GO:0015855 | pyrimidine transport | 0.0193196957794729 |
| GO:0005740 | mitochondrial envelope | 0.0193196957794729 |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 0.0193196957794729 |
| GO:0015297 | antiporter activity | 0.0246852861902725 |
| GO:0000267 | cell fraction | 0.0271937295608852 |
| GO:0044429 | mitochondrial part | 0.0271937295608852 |
| GO:0031090 | organelle membrane | 0.0271937295608852 |
| GO:0004781 | sulfate adenylyltransferase (ATP) activity | 0.0271937295608852 |
| GO:0015234 | thiamin transmembrane transporter activity | 0.0271937295608852 |
| GO:0015888 | thiamin transport | 0.0271937295608852 |
| GO:0046021 | regulation of transcription from RNA polymerase II promoter, mitotic | 0.0271937295608852 |
| GO:0050872 | white fat cell differentiation | 0.0271937295608852 |
| GO:0004779 | sulfate adenylyltransferase activity | 0.0271937295608852 |
| GO:0045896 | regulation of transcription, mitotic | 0.0271937295608852 |
| GO:0015205 | nucleobase transmembrane transporter activity | 0.0271937295608852 |
| GO:0006063 | uronic acid metabolic process | 0.0271937295608852 |
| GO:0046022 | positive regulation of transcription from RNA polymerase II promoter, mitotic | 0.0271937295608852 |
| GO:0019585 | glucuronate metabolic process | 0.0271937295608852 |
| GO:0005350 | pyrimidine transmembrane transporter activity | 0.0271937295608852 |
| GO:0045897 | positive regulation of transcription, mitotic | 0.0271937295608852 |
| GO:0004020 | adenylylsulfate kinase activity | 0.0271937295608852 |
| GO:0046914 | transition metal ion binding | 0.0282199347950114 |
| GO:0006820 | anion transport | 0.0297706266492854 |
| GO:0009117 | nucleotide metabolic process | 0.0351681350423161 |
| GO:0009152 | purine ribonucleotide biosynthetic process | 0.0351681350423161 |
| GO:0004322 | ferroxidase activity | 0.0351681350423161 |
| GO:0051181 | cofactor transport | 0.0351681350423161 |
| GO:0045600 | positive regulation of fat cell differentiation | 0.0351681350423161 |
| GO:0004528 | phosphodiesterase I activity | 0.0351681350423161 |
| GO:0016724 | oxidoreductase activity, oxidizing metal ions, oxygen as acceptor | 0.0351681350423161 |
| GO:0008518 | reduced folate carrier activity | 0.0351681350423161 |
| GO:0009260 | ribonucleotide biosynthetic process | 0.0387930557971987 |
| GO:0055086 | nucleobase, nucleoside and nucleotide metabolic process | 0.0397211960290843 |
| GO:0009150 | purine ribonucleotide metabolic process | 0.0412006989782975 |
| GO:0006164 | purine nucleotide biosynthetic process | 0.0412006989782975 |
| GO:0043169 | cation binding | 0.0412006989782975 |
| GO:0000103 | sulfate assimilation | 0.0412006989782975 |
| GO:0051180 | vitamin transport | 0.0412006989782975 |
| GO:0005381 | iron ion transmembrane transporter activity | 0.0412006989782975 |
| GO:0015701 | bicarbonate transport | 0.0412006989782975 |
| GO:0006791 | sulfur utilization | 0.0412006989782975 |
| GO:0009259 | ribonucleotide metabolic process | 0.0445872156103694 |
| GO:0006163 | purine nucleotide metabolic process | 0.0490314300689815 |
| GO:0004024 | alcohol dehydrogenase activity, zinc-dependent | 0.0496553565679924 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
{{{tfbs_overrepresentation_jaspar}}} |
