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MCL coexpression mm9:1009

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:120336020..120336044,-p2@Msrb3
Mm9::chr10:120336045..120336067,-p3@Msrb3
Mm9::chr10:120336082..120336093,-p7@Msrb3
Mm9::chr10:120336107..120336118,-p5@Msrb3
Mm9::chr10:126632296..126632354,+p1@F420014N23Rik
Mm9::chr10:39332941..39332960,+p2@Traf3ip2
Mm9::chr13:74946300..74946335,-p9@Cast


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030161calpain inhibitor activity0.00813475747043468
GO:0001783B cell apoptosis0.00813475747043468
GO:0030091protein repair0.00813475747043468
GO:0000318protein-methionine-R-oxide reductase activity0.00813475747043468
GO:0016671oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor0.0173493954035186
GO:0048305immunoglobulin secretion0.0198762477607476
GO:0016667oxidoreductase activity, acting on sulfur group of donors0.0309606958326231
GO:0004869cysteine protease inhibitor activity0.036101018137574
GO:0009306protein secretion0.036101018137574
GO:0002377immunoglobulin production0.0393613436801453
GO:0002440production of molecular mediator of immune response0.0393613436801453



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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