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MCL coexpression mm9:2274

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Phase1 CAGE Peaks

 Short description
Mm9::chr19:7015918..7016008,-p1@Gpr137
Mm9::chr4:147534740..147534761,+p3@Fbxo2
Mm9::chr4:147534765..147534789,+p2@Fbxo2
Mm9::chr9:54509651..54509662,-p4@Acsbg1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0031957very-long-chain-fatty-acid-CoA ligase activity0.00953267955952446
GO:0001948glycoprotein binding0.011436082012144
GO:0030433ER-associated protein catabolic process0.011436082012144
GO:0000038very-long-chain fatty acid metabolic process0.011436082012144
GO:0006515misfolded or incompletely synthesized protein catabolic process0.011436082012144
GO:0006516glycoprotein catabolic process0.0133362479456937
GO:0004467long-chain-fatty-acid-CoA ligase activity0.0133362479456937
GO:0043161proteasomal ubiquitin-dependent protein catabolic process0.0133362479456937
GO:0015645fatty-acid ligase activity0.0133362479456937
GO:0001676long-chain fatty acid metabolic process0.0133362479456937
GO:0016877ligase activity, forming carbon-sulfur bonds0.0199079506232692



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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