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MCL coexpression mm9:884

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:102342088..102342102,-p@chr11:102342088..102342102
-
Mm9::chr11:29363676..29363691,+p4@Ccdc88a
Mm9::chr11:29363735..29363749,+p3@Ccdc88a
Mm9::chr11:77107497..77107501,+p@chr11:77107497..77107501
+
Mm9::chr14:57291296..57291310,+p2@Mphosph8
Mm9::chr14:57292752..57292765,+p@chr14:57292752..57292765
+
Mm9::chr14:57293460..57293463,+p@chr14:57293460..57293463
+
Mm9::chr19:60018977..60019003,-p4@Rab11fip2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0032148activation of protein kinase B0.00542376595628116
GO:0043422protein kinase B binding0.00542376595628116
GO:0006259DNA metabolic process0.029822540857081
GO:0006275regulation of DNA replication0.029822540857081
GO:0051052regulation of DNA metabolic process0.0356792078839629
GO:0032147activation of protein kinase activity0.0356792078839629
GO:0008017microtubule binding0.0356792078839629
GO:0006261DNA-dependent DNA replication0.0356792078839629
GO:0019901protein kinase binding0.0356792078839629
GO:0019900kinase binding0.0356792078839629
GO:0001932regulation of protein amino acid phosphorylation0.0356792078839629
GO:0033238regulation of amine metabolic process0.0356792078839629
GO:0006521regulation of amino acid metabolic process0.0356792078839629
GO:0015631tubulin binding0.0356792078839629
GO:0042325regulation of phosphorylation0.0356792078839629
GO:0051174regulation of phosphorus metabolic process0.0356792078839629
GO:0019220regulation of phosphate metabolic process0.0356792078839629
GO:0045860positive regulation of protein kinase activity0.0470658445862631
GO:0033674positive regulation of kinase activity0.0470658445862631
GO:0051347positive regulation of transferase activity0.0470658445862631
GO:0003682chromatin binding0.0470658445862631
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0470658445862631
GO:0031323regulation of cellular metabolic process0.0470658445862631
GO:0045859regulation of protein kinase activity0.0470658445862631
GO:0019222regulation of metabolic process0.0470658445862631
GO:0006333chromatin assembly or disassembly0.0470658445862631
GO:0043549regulation of kinase activity0.0470658445862631
GO:0019899enzyme binding0.0470658445862631
GO:0043085positive regulation of catalytic activity0.0470658445862631
GO:0006260DNA replication0.0470658445862631
GO:0051338regulation of transferase activity0.0470658445862631



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
structure with developmental contribution from neural crest6.05e-0992
embryo5.23e-08320
occipital lobe7.68e-0810
visual cortex7.68e-0810
neocortex7.68e-0810


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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