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MCL coexpression mm9:1304

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:73012488..73012510,-p2@Ctns
Mm9::chr13:106084899..106084909,-p10@Rnf180
Mm9::chr14:56983841..56983853,+p1@Atp12a
Mm9::chr2:113245260..113245269,+p17@Fmn1
Mm9::chr2:113245271..113245284,+p11@Fmn1
Mm9::chr2:113245288..113245314,+p6@Fmn1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0015184L-cystine transmembrane transporter activity0.00467503058857905
GO:0000101sulfur amino acid transport0.00467503058857905
GO:0051125regulation of actin nucleation0.00467503058857905
GO:0000099sulfur amino acid transmembrane transporter activity0.00467503058857905
GO:0015811L-cystine transport0.00467503058857905
GO:0051127positive regulation of actin nucleation0.00467503058857905
GO:0008900hydrogen:potassium-exchanging ATPase activity0.00801367951130475
GO:0030838positive regulation of actin filament polymerization0.00934852440535652
GO:0045010actin nucleation0.00934852440535652
GO:0051130positive regulation of cellular component organization and biogenesis0.016823195403582
GO:0015807L-amino acid transport0.023357868680412
GO:0030833regulation of actin filament polymerization0.023357868680412
GO:0030041actin filament polymerization0.0366328029020975
GO:0015179L-amino acid transmembrane transporter activity0.0459991902383788
GO:0008064regulation of actin polymerization and/or depolymerization0.0460173561850889
GO:0032535regulation of cellular component size0.0460173561850889
GO:0032956regulation of actin cytoskeleton organization and biogenesis0.0460173561850889
GO:0030832regulation of actin filament length0.0460173561850889
GO:0051493regulation of cytoskeleton organization and biogenesis0.0460173561850889
GO:0033043regulation of organelle organization and biogenesis0.0460173561850889
GO:0015171amino acid transmembrane transporter activity0.0460173561850889
GO:0051258protein polymerization0.0460173561850889
GO:0022891substrate-specific transmembrane transporter activity0.0460173561850889
GO:0008154actin polymerization and/or depolymerization0.0460173561850889
GO:0006865amino acid transport0.0460173561850889
GO:0015837amine transport0.0460173561850889
GO:0015992proton transport0.0460173561850889
GO:0022857transmembrane transporter activity0.0460173561850889
GO:0051128regulation of cellular component organization and biogenesis0.0460173561850889
GO:0046943carboxylic acid transmembrane transporter activity0.0460173561850889
GO:0006818hydrogen transport0.0460173561850889
GO:0005342organic acid transmembrane transporter activity0.0460173561850889
GO:0044425membrane part0.0460173561850889
GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism0.0460173561850889
GO:0046942carboxylic acid transport0.0460173561850889
GO:0015849organic acid transport0.0460173561850889
GO:0005912adherens junction0.0460173561850889
GO:0022892substrate-specific transporter activity0.0465164382921448



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
surface structure2.64e-1222
zone of skin1.49e-095
skin epidermis1.49e-095
skin of body1.49e-095
integument1.49e-095
surface1.49e-095
outer epithelium1.49e-095
integumental system1.49e-095
enveloping layer of ectoderm1.49e-095


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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