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MCL coexpression mm9:2433

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Phase1 CAGE Peaks

 Short description
Mm9::chr5:93326982..93327000,+p6@Shroom3
Mm9::chr5:93327007..93327078,+p3@Shroom3
Mm9::chr5:93327079..93327101,+p5@Shroom3
Mm9::chr9:107507626..107507662,-p2@Sema3b


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0002065columnar/cuboidal epithelial cell differentiation0.00876544222422034
GO:0002066columnar/cuboidal epithelial cell development0.00876544222422034
GO:0002064epithelial cell development0.0204498970139181
GO:0007399nervous system development0.0228906919482546
GO:0030855epithelial cell differentiation0.0306781855020501
GO:0001843neural tube closure0.0306781855020501
GO:0014020primary neural tube formation0.0306781855020501
GO:0022603regulation of anatomical structure morphogenesis0.0306781855020501
GO:0008360regulation of cell shape0.0306781855020501
GO:0022604regulation of cell morphogenesis0.0306781855020501
GO:0016324apical plasma membrane0.0306781855020501
GO:0001841neural tube formation0.0306781855020501
GO:0001839neural plate morphogenesis0.0306781855020501
GO:0001840neural plate development0.0306781855020501
GO:0001838embryonic epithelial tube formation0.0306781855020501
GO:0005912adherens junction0.0306781855020501
GO:0021915neural tube development0.0306781855020501
GO:0016331morphogenesis of embryonic epithelium0.0306781855020501
GO:0048731system development0.0306781855020501
GO:0045177apical part of cell0.0306781855020501
GO:0048869cellular developmental process0.0306781855020501
GO:0030154cell differentiation0.0306781855020501
GO:0043296apical junction complex0.032791165650253
GO:0016327apicolateral plasma membrane0.032791165650253
GO:0048856anatomical structure development0.0348025444443735
GO:0002009morphogenesis of an epithelium0.0403686812337117
GO:0007275multicellular organismal development0.0403686812337117
GO:0035239tube morphogenesis0.0448085718115091
GO:0005911intercellular junction0.0448085718115091
GO:0030036actin cytoskeleton organization and biogenesis0.0448085718115091
GO:0030029actin filament-based process0.046446441539182



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
gastrointestinal system1.26e-2147
intestine2.99e-1931
mucosa2.26e-0915
intestinal mucosa1.45e-0813
anatomical wall1.45e-0813
wall of intestine1.45e-0813
gastrointestinal system mucosa1.45e-0813
multi-cellular organism5.67e-08333
organ component layer1.56e-0724
embryo3.31e-07320


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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