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MCL coexpression mm9:330

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:79482366..79482435,+p3@Hmha1
Mm9::chr11:68505599..68505628,+p1@Myh10
Mm9::chr14:32082684..32082746,-p1@Dnahc1
Mm9::chr14:56472962..56473043,+p1@Nynrin
Mm9::chr15:26825333..26825340,-p2@Fbxl7
Mm9::chr17:46787557..46787583,+p1@Cul7
Mm9::chr17:46787591..46787610,+p2@Cul7
Mm9::chr2:152240475..152240491,-p@chr2:152240475..152240491
-
Mm9::chr2:152240508..152240545,-p1@Zcchc3
Mm9::chr2:152240554..152240570,-p3@Zcchc3
Mm9::chr2:152240575..152240597,-p2@Zcchc3
Mm9::chr2:153172121..153172156,-p1@ENSMUST00000139636
Mm9::chr2:156665526..156665594,-p1@ENSMUST00000134838
p1@ENSMUST00000137463
Mm9::chr3:46251861..46251902,-p1@Pabpc4l
Mm9::chr5:37729838..37729858,+p2@Evc2
Mm9::chr6:38249236..38249290,-p1@Zc3hav1l
Mm9::chr6:48395825..48395846,-p3@Zfp467
Mm9::chr7:25084406..25084425,-p3@Zfp61
Mm9::chr7:69608158..69608162,-p@chr7:69608158..69608162
-
Mm9::chr8:32297789..32297829,+p1@Fut10
Mm9::chr8:87162861..87162916,+p1@Cacna1a
Mm9::chr9:72772890..72772904,+p@chr9:72772890..72772904
+
Mm9::chr9:8004414..8004436,-p4@Yap1
Mm9::chrX:157600676..157600707,+p1@Scml2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0021680cerebellar Purkinje cell layer development0.0115143358490151
GO:0021695cerebellar cortex development0.0115143358490151
GO:0022037metencephalon development0.0115143358490151
GO:0021549cerebellum development0.0115143358490151
GO:0050885neuromuscular process controlling balance0.0138358327149211
GO:0030902hindbrain development0.0138358327149211
GO:0050905neuromuscular process0.0138358327149211
GO:0030425dendrite0.0138358327149211
GO:0050793regulation of developmental process0.0138358327149211
GO:0043025cell soma0.0138358327149211
GO:0021578hindbrain maturation0.0138358327149211
GO:0021548pons development0.0138358327149211
GO:0032353negative regulation of hormone biosynthetic process0.0138358327149211
GO:0006930substrate-bound cell migration, cell extension0.0138358327149211
GO:0048791calcium ion-dependent exocytosis of neurotransmitter0.0138358327149211
GO:0021626central nervous system maturation0.0138358327149211
GO:0021678third ventricle development0.0138358327149211
GO:0021592fourth ventricle development0.0138358327149211
GO:0032351negative regulation of hormone metabolic process0.0138358327149211
GO:0021679cerebellar molecular layer development0.0138358327149211
GO:0021590cerebellum maturation0.0138358327149211
GO:0021750vestibular nucleus development0.0138358327149211
GO:0044463cell projection part0.0177364098987912
GO:0046885regulation of hormone biosynthetic process0.0190185372696203
GO:0021591ventricular system development0.0190185372696203
GO:0021670lateral ventricle development0.0190185372696203
GO:0050883musculoskeletal movement, spinal reflex action0.0190185372696203
GO:0014056regulation of acetylcholine secretion0.0190185372696203
GO:0043531ADP binding0.0190185372696203
GO:0055015ventricular cardiac muscle cell development0.0190185372696203
GO:0014051gamma-aminobutyric acid secretion0.0190185372696203
GO:0014055acetylcholine secretion0.0190185372696203
GO:0006887exocytosis0.0192529709852802
GO:0042995cell projection0.0206118188554981
GO:0021700developmental maturation0.0207767562907057
GO:0030705cytoskeleton-dependent intracellular transport0.0217289218860015
GO:0055064chloride ion homeostasis0.0217289218860015
GO:0030644cellular chloride ion homeostasis0.0217289218860015
GO:0048857neural nucleus development0.0217289218860015
GO:0007097nuclear migration0.0217289218860015
GO:0032350regulation of hormone metabolic process0.0217289218860015
GO:0000281cytokinesis after mitosis0.0217289218860015
GO:0043005neuron projection0.0233933269220122
GO:0055083monovalent inorganic anion homeostasis0.0233933269220122
GO:0033205cytokinesis during cell cycle0.0233933269220122
GO:0055003cardiac myofibril assembly0.0233933269220122
GO:0017158regulation of calcium ion-dependent exocytosis0.0233933269220122
GO:0045601regulation of endothelial cell differentiation0.0233933269220122
GO:0030898actin-dependent ATPase activity0.0233933269220122
GO:0001778plasma membrane repair0.0233933269220122
GO:0060024rhythmic synaptic transmission0.0233933269220122
GO:0030320cellular monovalent inorganic anion homeostasis0.0233933269220122
GO:0050881musculoskeletal movement0.0266685637761362
GO:0006929substrate-bound cell migration0.0266685637761362
GO:0000146microfilament motor activity0.0266685637761362
GO:0048266behavioral response to pain0.0266685637761362
GO:0050879multicellular organismal movement0.0266685637761362
GO:0055012ventricular cardiac muscle cell differentiation0.0294125842816465
GO:0040023establishment of nucleus localization0.0294125842816465
GO:0055013cardiac muscle cell development0.0294125842816465
GO:0051647nucleus localization0.0294125842816465
GO:0008331high voltage-gated calcium channel activity0.0294125842816465
GO:0007409axonogenesis0.0324521622352901
GO:0055081anion homeostasis0.0327210672450276
GO:0030002cellular anion homeostasis0.0327210672450276
GO:0048667neuron morphogenesis during differentiation0.0340857635744828
GO:0048812neurite morphogenesis0.0340857635744828
GO:0060004reflex0.0357349363514642
GO:0045045secretory pathway0.0364386563812879
GO:0021692cerebellar Purkinje cell layer morphogenesis0.0364386563812879
GO:0035249synaptic transmission, glutamatergic0.0364386563812879
GO:0021694cerebellar Purkinje cell layer formation0.0364386563812879
GO:0007512adult heart development0.0364386563812879
GO:0060041retina development in camera-type eye0.0364386563812879
GO:0021702cerebellar Purkinje cell differentiation0.0364386563812879
GO:0007420brain development0.0370200017217645
GO:0000904cellular morphogenesis during differentiation0.0370200017217645
GO:0042403thyroid hormone metabolic process0.0370200017217645
GO:0043197dendritic spine0.0370200017217645
GO:0007009plasma membrane organization and biogenesis0.0370200017217645
GO:0045446endothelial cell differentiation0.0370200017217645
GO:0055007cardiac muscle cell differentiation0.0370200017217645
GO:0031175neurite development0.0383700978135761
GO:0043113receptor clustering0.0383700978135761
GO:0021697cerebellar cortex formation0.0383700978135761
GO:0021533cell differentiation in hindbrain0.0383700978135761
GO:0008417fucosyltransferase activity0.0383700978135761
GO:0032940secretion by cell0.0404508270494897
GO:0048265response to pain0.0404508270494897
GO:0005858axonemal dynein complex0.0404508270494897
GO:0031594neuromuscular junction0.0419443405874678
GO:0007274neuromuscular synaptic transmission0.0419443405874678
GO:0007172signal complex assembly0.0419443405874678
GO:0048813dendrite morphogenesis0.0419443405874678
GO:0048666neuron development0.0422104579164527
GO:0030239myofibril assembly0.042488017382512
GO:0005891voltage-gated calcium channel complex0.042488017382512
GO:0055002striated muscle cell development0.042488017382512
GO:0021696cerebellar cortex morphogenesis0.042488017382512
GO:0007417central nervous system development0.042488017382512
GO:0044447axoneme part0.042488017382512
GO:0021587cerebellum morphogenesis0.042488017382512
GO:0035051cardiac cell differentiation0.042488017382512
GO:0030427site of polarized growth0.042488017382512
GO:0030048actin filament-based movement0.042488017382512
GO:0030426growth cone0.042488017382512
GO:0055001muscle cell development0.042488017382512
GO:0051649establishment of cellular localization0.042488017382512
GO:0051641cellular localization0.0436779792210924
GO:0021575hindbrain morphogenesis0.0436779792210924
GO:0000096sulfur amino acid metabolic process0.0436779792210924
GO:0006950response to stress0.0451729903323541
GO:0007204elevation of cytosolic calcium ion concentration0.0451729903323541
GO:0051899membrane depolarization0.0451729903323541
GO:0007416synaptogenesis0.0465897799802007
GO:0046928regulation of neurotransmitter secretion0.0465897799802007
GO:0017157regulation of exocytosis0.0465897799802007
GO:0046903secretion0.0469226809493046
GO:0001725stress fiber0.0469226809493046
GO:0007214gamma-aminobutyric acid signaling pathway0.0469226809493046
GO:0031032actomyosin structure organization and biogenesis0.0469226809493046
GO:0051480cytosolic calcium ion homeostasis0.0469226809493046
GO:0032990cell part morphogenesis0.0469226809493046
GO:0048858cell projection morphogenesis0.0469226809493046
GO:0030030cell projection organization and biogenesis0.0469226809493046
GO:0017156calcium ion-dependent exocytosis0.0469226809493046
GO:0032432actin filament bundle0.0469226809493046
GO:0050804regulation of synaptic transmission0.0469226809493046
GO:0051969regulation of transmission of nerve impulse0.0469226809493046
GO:0030182neuron differentiation0.047772663659699
GO:0048628myoblast maturation0.047772663659699
GO:0051656establishment of organelle localization0.047772663659699
GO:0005245voltage-gated calcium channel activity0.047772663659699
GO:0005930axoneme0.048928832684291
GO:0007628adult walking behavior0.048928832684291
GO:0048627myoblast development0.048928832684291
GO:0015630microtubule cytoskeleton0.0491975845702045
GO:0043234protein complex0.0496764062639832
GO:0043524negative regulation of neuron apoptosis0.0496764062639832
GO:0021537telencephalon development0.0496764062639832



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
multi-cellular organism9.09e-09333
embryo4.06e-07320


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.14.99612
MA0004.10.398663
MA0006.11.07907
MA0007.10.756875
MA0009.10.452863
MA0014.11.88823
MA0017.10.0561984
MA0019.10.30302
MA0024.10.415603
MA0025.10.660968
MA0027.12.04174
MA0028.10.417056
MA0029.10.397373
MA0030.10.402861
MA0031.10.373333
MA0038.10.62805
MA0040.10.463641
MA0041.10.0860551
MA0042.10.0797095
MA0043.10.53743
MA0046.10.483941
MA0048.10.299714
MA0050.10.149886
MA0051.10.226644
MA0052.10.47061
MA0055.10.0154442
MA0056.10
MA0057.10.644264
MA0058.10.949115
MA0059.11.47725
MA0060.10.235925
MA0061.10.122344
MA0063.10
MA0066.10.212546
MA0067.10.764133
MA0068.10.275297
MA0069.10.470904
MA0070.10.462521
MA0071.10.149369
MA0072.10.455219
MA0073.12.18847
MA0074.10.187944
MA0076.10.229034
MA0077.10.436665
MA0078.10.250627
MA0081.10.644573
MA0083.10.536725
MA0084.11.07765
MA0087.10.4987
MA0088.12.47003
MA0089.10
MA0090.11.16834
MA0091.10.134352
MA0092.10.349135
MA0093.10.76125
MA0095.10
MA0098.10
MA0100.10.180237
MA0101.10.292678
MA0103.10.218786
MA0105.11.67437
MA0106.11.31386
MA0107.10.211319
MA0108.20.85894
MA0109.10
MA0111.10.115252
MA0113.10.2357
MA0114.10.530742
MA0115.10.539917
MA0116.10.394187
MA0117.10.511373
MA0119.10.0869793
MA0122.10.528896
MA0124.10.714453
MA0125.10.646095
MA0130.10
MA0131.10.299487
MA0132.10
MA0133.10
MA0135.10.569948
MA0136.10.201456
MA0139.11.24632
MA0140.10.180161
MA0141.10.24332
MA0142.10.361451
MA0143.10.247626
MA0144.10.858034
MA0145.10.663753
MA0146.13.65184
MA0147.11.30981
MA0148.10.136186
MA0149.10.623584
MA0062.20.993556
MA0035.20.18328
MA0039.24.22405
MA0138.20.293335
MA0002.20.366396
MA0137.20.514948
MA0104.21.36483
MA0047.20.219739
MA0112.20.171352
MA0065.21.5037
MA0150.10.11804
MA0151.10
MA0152.10.219814
MA0153.10.584906
MA0154.10.701663
MA0155.12.05598
MA0156.10.0637507
MA0157.10.335532
MA0158.10
MA0159.10.145533
MA0160.10.137981
MA0161.10
MA0162.14.94822
MA0163.12.36398
MA0164.10.201705
MA0080.20.0584358
MA0018.20.208409
MA0099.20.288477
MA0079.24.25662
MA0102.21.12863
MA0258.10.107482
MA0259.11.24869
MA0442.10
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