Novel motif:45

name:	motif45_GCTCNGG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0043503	skeletal muscle fiber adaptation	3.800215e-11
GO:0010625	positive regulation of Schwann cell proliferation	1.228535e-10
GO:0032863	activation of Rac GTPase activity	8.395160e-10
GO:0050432	catecholamine secretion	9.167752e-10
GO:0000072	M phase specific microtubule process	1.991728e-9
GO:0043089	positive regulation of Cdc42 GTPase activity	3.252148e-9
GO:0010624	regulation of Schwann cell proliferation	4.301568e-9
GO:0032862	activation of Rho GTPase activity	1.614074e-8
GO:0035873	lactate transmembrane transport	1.716047e-8
GO:0048241	epinephrine transport	2.217435e-8
GO:0055010	ventricular cardiac muscle tissue morphogenesis	4.128903e-8
GO:0007386	compartment pattern specification	4.480119e-8
GO:0032202	telomere assembly	5.241054e-8
GO:0045007	depurination	6.453636e-8
GO:0048242	epinephrine secretion	1.288550e-7
GO:0003229	ventricular cardiac muscle tissue development	2.045595e-7
GO:0010897	negative regulation of triglyceride catabolic process	2.427007e-7
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.427007e-7
GO:0072668	tubulin complex biogenesis	2.859162e-7
GO:0006929	substrate-dependent cell migration	3.571073e-7
GO:0031442	positive regulation of mRNA 3'-end processing	4.924524e-7
GO:0035357	peroxisome proliferator activated receptor signaling pathway	6.833577e-7
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	7.899620e-7
GO:0032312	regulation of ARF GTPase activity	8.563663e-7
GO:0010982	regulation of high-density lipoprotein particle clearance	1.333689e-6
GO:0015874	norepinephrine transport	1.754924e-6
GO:0051788	response to misfolded protein	1.859767e-6
GO:0010310	regulation of hydrogen peroxide metabolic process	2.222834e-6
GO:0010989	negative regulation of low-density lipoprotein particle clearance	2.316032e-6
GO:0051973	positive regulation of telomerase activity	2.544425e-6
GO:0006285	base-excision repair, AP site formation	2.572040e-6
GO:0090207	regulation of triglyceride metabolic process	2.709554e-6
GO:0050779	RNA destabilization	3.263334e-6
GO:0043585	nose morphogenesis	4.587680e-6
GO:0051972	regulation of telomerase activity	4.786325e-6
GO:0019388	galactose catabolic process	4.875799e-6
GO:0045006	DNA deamination	7.073072e-6
GO:0060251	regulation of glial cell proliferation	7.157574e-6
GO:0032462	regulation of protein homooligomerization	7.537737e-6
GO:0009155	purine deoxyribonucleotide catabolic process	7.747410e-6
GO:0001757	somite specification	9.546684e-6
GO:0009264	deoxyribonucleotide catabolic process	1.137465e-5
GO:0045217	cell-cell junction maintenance	1.137465e-5
GO:0051935	glutamate uptake involved in synaptic transmission	1.139649e-5
GO:0045717	negative regulation of fatty acid biosynthetic process	1.264461e-5
GO:0051055	negative regulation of lipid biosynthetic process	1.268604e-5
GO:0070307	lens fiber cell development	1.412593e-5
GO:0060020	Bergmann glial cell differentiation	1.627454e-5
GO:0070345	negative regulation of fat cell proliferation	1.658073e-5
GO:0032012	regulation of ARF protein signal transduction	1.673976e-5
GO:0006544	glycine metabolic process	1.693361e-5
GO:0015816	glycine transport	1.784639e-5
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.806567e-5
GO:0048243	norepinephrine secretion	1.891434e-5
GO:0007021	tubulin complex assembly	2.032841e-5
GO:0071956	cellular component maintenance at cellular level	2.121548e-5
GO:0019693	ribose phosphate metabolic process	2.121548e-5
GO:0051580	regulation of neurotransmitter uptake	2.246172e-5
GO:0090209	negative regulation of triglyceride metabolic process	2.379039e-5
GO:0000389	nuclear mRNA 3'-splice site recognition	2.423444e-5
GO:0061157	mRNA destabilization	2.502846e-5
GO:0032972	regulation of muscle filament sliding speed	2.502846e-5
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	2.502846e-5
GO:2000210	positive regulation of anoikis	2.679254e-5
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	2.721357e-5
GO:0006689	ganglioside catabolic process	3.189885e-5
GO:0045618	positive regulation of keratinocyte differentiation	3.230987e-5
GO:0006108	malate metabolic process	3.721544e-5
GO:0043491	protein kinase B signaling cascade	3.764095e-5
GO:0031848	protection from non-homologous end joining at telomere	3.808473e-5
GO:0060430	lung saccule development	3.811240e-5
GO:0045922	negative regulation of fatty acid metabolic process	3.823430e-5
GO:0001560	regulation of cell growth by extracellular stimulus	4.760949e-5
GO:0060252	positive regulation of glial cell proliferation	5.094368e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	5.427960e-5
GO:0043088	regulation of Cdc42 GTPase activity	6.648603e-5
GO:0015862	uridine transport	6.787233e-5
GO:0070383	DNA cytosine deamination	7.648610e-5
GO:0055075	potassium ion homeostasis	7.958131e-5
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	9.411541e-5
GO:0030037	actin filament reorganization involved in cell cycle	1.196946e-4
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	1.199846e-4
GO:0042398	cellular modified amino acid biosynthetic process	1.500858e-4
GO:2000209	regulation of anoikis	1.519327e-4
GO:0071071	regulation of phospholipid biosynthetic process	1.578048e-4
GO:0060038	cardiac muscle cell proliferation	1.597623e-4
GO:0010866	regulation of triglyceride biosynthetic process	1.655249e-4
GO:0032463	negative regulation of protein homooligomerization	1.664983e-4
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	1.722722e-4
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	1.749452e-4
GO:0032203	telomere formation via telomerase	1.749452e-4
GO:0061205	paramesonephric duct development	1.863472e-4
GO:0030853	negative regulation of granulocyte differentiation	1.928016e-4
GO:0072089	stem cell proliferation	1.992239e-4
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	2.010654e-4
GO:0010529	negative regulation of transposition	2.108259e-4
GO:0016052	carbohydrate catabolic process	2.128358e-4
GO:0006014	D-ribose metabolic process	2.144514e-4
GO:0002071	glandular epithelial cell maturation	2.189755e-4
GO:0009052	pentose-phosphate shunt, non-oxidative branch	2.208646e-4
GO:0071072	negative regulation of phospholipid biosynthetic process	2.265046e-4
GO:0006423	cysteinyl-tRNA aminoacylation	2.432898e-4
GO:0006476	protein deacetylation	2.619422e-4
GO:0006284	base-excision repair	2.670213e-4
GO:0030149	sphingolipid catabolic process	2.695557e-4
GO:0006884	cell volume homeostasis	2.995001e-4
GO:0051532	regulation of NFAT protein import into nucleus	3.009442e-4
GO:0090303	positive regulation of wound healing	3.022039e-4
GO:0035470	positive regulation of vascular wound healing	3.041869e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	3.041869e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	3.041869e-4
GO:0046890	regulation of lipid biosynthetic process	3.117222e-4
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	3.118391e-4
GO:0002357	defense response to tumor cell	3.316478e-4
GO:0014037	Schwann cell differentiation	3.385952e-4
GO:0046210	nitric oxide catabolic process	3.538984e-4
GO:0090346	cellular organofluorine metabolic process	3.538984e-4
GO:0043602	nitrate catabolic process	3.538984e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	3.538984e-4
GO:0002522	leukocyte migration involved in immune response	3.538984e-4
GO:0032793	positive regulation of CREB transcription factor activity	3.568746e-4
GO:0048627	myoblast development	3.798284e-4
GO:0007296	vitellogenesis	4.078960e-4
GO:0050685	positive regulation of mRNA processing	4.097065e-4
GO:0051496	positive regulation of stress fiber assembly	4.473955e-4
GO:0018208	peptidyl-proline modification	4.493349e-4
GO:0046466	membrane lipid catabolic process	4.515288e-4
GO:0071732	cellular response to nitric oxide	4.611698e-4
GO:0045918	negative regulation of cytolysis	4.643164e-4
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	4.715972e-4
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	4.715972e-4
GO:0009262	deoxyribonucleotide metabolic process	4.743224e-4
GO:0035601	protein deacylation	4.751700e-4
GO:0014807	regulation of somitogenesis	4.920323e-4
GO:0031330	negative regulation of cellular catabolic process	4.921854e-4
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	4.924032e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	4.924032e-4
GO:0005978	glycogen biosynthetic process	5.013177e-4
GO:0018205	peptidyl-lysine modification	5.016399e-4
GO:0071300	cellular response to retinoic acid	5.108519e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	5.162869e-4
GO:0072109	glomerular mesangium development	5.168663e-4
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	5.238854e-4
GO:0007253	cytoplasmic sequestering of NF-kappaB	5.238854e-4
GO:0006479	protein methylation	5.313727e-4
GO:0046687	response to chromate	5.339851e-4
GO:0033986	response to methanol	5.339851e-4
GO:0015809	arginine transport	5.489767e-4
GO:0002309	T cell proliferation involved in immune response	5.705684e-4
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	5.705684e-4
GO:0019321	pentose metabolic process	5.802210e-4
GO:0002438	acute inflammatory response to antigenic stimulus	5.823745e-4
GO:0001830	trophectodermal cell fate commitment	5.823745e-4
GO:0006098	pentose-phosphate shunt	5.879328e-4
GO:0051534	negative regulation of NFAT protein import into nucleus	6.007153e-4
GO:0055009	atrial cardiac muscle tissue morphogenesis	6.026132e-4
GO:0021892	cerebral cortex GABAergic interneuron differentiation	6.028195e-4
GO:0019318	hexose metabolic process	6.116454e-4
GO:0090150	establishment of protein localization in membrane	6.262989e-4
GO:0060419	heart growth	6.312503e-4
GO:0006386	termination of RNA polymerase III transcription	6.405376e-4
GO:0006385	transcription elongation from RNA polymerase III promoter	6.405376e-4
GO:0007512	adult heart development	6.507983e-4
GO:0035767	endothelial cell chemotaxis	6.593727e-4
GO:0016571	histone methylation	6.628179e-4
GO:0000413	protein peptidyl-prolyl isomerization	6.722114e-4
GO:0046500	S-adenosylmethionine metabolic process	6.730319e-4
GO:0045342	MHC class II biosynthetic process	6.799632e-4
GO:0043091	L-arginine import	6.799632e-4
GO:0070839	divalent metal ion export	6.799632e-4
GO:0006876	cellular cadmium ion homeostasis	6.799632e-4
GO:0015707	nitrite transport	6.799632e-4
GO:0032632	interleukin-3 production	6.799632e-4
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	6.862529e-4
GO:0046655	folic acid metabolic process	7.089927e-4
GO:0015804	neutral amino acid transport	7.266130e-4
GO:0035854	eosinophil fate commitment	7.650654e-4
GO:0030222	eosinophil differentiation	7.650654e-4
GO:0031440	regulation of mRNA 3'-end processing	7.671420e-4
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	7.769282e-4
GO:0018277	protein deamination	7.769282e-4
GO:0006420	arginyl-tRNA aminoacylation	7.769282e-4
GO:0014044	Schwann cell development	8.037223e-4
GO:0006984	ER-nucleus signaling pathway	8.177153e-4
GO:0046519	sphingoid metabolic process	9.210539e-4
GO:0002067	glandular epithelial cell differentiation	9.296357e-4
GO:0050772	positive regulation of axonogenesis	9.368464e-4
GO:0032856	activation of Ras GTPase activity	9.395766e-4
GO:0015864	pyrimidine nucleoside transport	9.425840e-4
GO:0090205	positive regulation of cholesterol metabolic process	9.458972e-4
GO:0030035	microspike assembly	9.517635e-4
GO:0070574	cadmium ion transmembrane transport	9.580267e-4
GO:0009151	purine deoxyribonucleotide metabolic process	9.695661e-4
GO:0071421	manganese ion transmembrane transport	9.857018e-4
GO:0010954	positive regulation of protein processing	1.010367e-3
GO:0071585	detoxification of cadmium ion	1.017391e-3
GO:0048384	retinoic acid receptor signaling pathway	1.026192e-3
GO:0003416	endochondral bone growth	1.029077e-3
GO:0009394	2'-deoxyribonucleotide metabolic process	1.093204e-3
GO:0055017	cardiac muscle tissue growth	1.106914e-3
GO:0019254	carnitine metabolic process, CoA-linked	1.122709e-3
GO:0090002	establishment of protein localization in plasma membrane	1.162194e-3
GO:0045606	positive regulation of epidermal cell differentiation	1.168049e-3
GO:0071874	cellular response to norepinephrine stimulus	1.193628e-3
GO:0034767	positive regulation of ion transmembrane transport	1.213476e-3
GO:0046847	filopodium assembly	1.232176e-3
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	1.263391e-3
GO:0006400	tRNA modification	1.272885e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.278106e-3
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	1.278106e-3
GO:0060014	granulosa cell differentiation	1.281154e-3
GO:0010511	regulation of phosphatidylinositol biosynthetic process	1.281154e-3
GO:0072144	glomerular mesangial cell development	1.294310e-3
GO:0072011	glomerular endothelium development	1.294310e-3
GO:0006353	transcription termination, DNA-dependent	1.320213e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	1.329921e-3
GO:0034651	cortisol biosynthetic process	1.330723e-3
GO:0035865	cellular response to potassium ion	1.330723e-3
GO:0032342	aldosterone biosynthetic process	1.330723e-3
GO:0014895	smooth muscle hypertrophy	1.330723e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	1.330723e-3
GO:0060385	axonogenesis involved in innervation	1.331546e-3
GO:0055099	response to high density lipoprotein particle stimulus	1.351088e-3
GO:0016233	telomere capping	1.359346e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	1.391623e-3
GO:0006672	ceramide metabolic process	1.426676e-3
GO:0006337	nucleosome disassembly	1.468116e-3
GO:0032926	negative regulation of activin receptor signaling pathway	1.496475e-3
GO:0014888	striated muscle adaptation	1.536584e-3
GO:0014829	vascular smooth muscle contraction	1.538583e-3
GO:0000185	activation of MAPKKK activity	1.539392e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.541147e-3
GO:0071276	cellular response to cadmium ion	1.557966e-3
GO:0034637	cellular carbohydrate biosynthetic process	1.558152e-3
GO:0032717	negative regulation of interleukin-8 production	1.576511e-3
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.582345e-3
GO:0070230	positive regulation of lymphocyte apoptosis	1.597493e-3
GO:0045109	intermediate filament organization	1.620084e-3
GO:0021526	medial motor column neuron differentiation	1.649408e-3
GO:0035329	hippo signaling cascade	1.682585e-3
GO:0019060	intracellular transport of viral proteins in host cell	1.710071e-3
GO:0034014	response to triglyceride	1.735367e-3
GO:0006927	transformed cell apoptosis	1.735367e-3
GO:0043171	peptide catabolic process	1.737019e-3
GO:0010610	regulation of mRNA stability involved in response to stress	1.767216e-3
GO:0010756	positive regulation of plasminogen activation	1.767216e-3
GO:0034465	response to carbon monoxide	1.781181e-3
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	1.783076e-3
GO:0008334	histone mRNA metabolic process	1.795250e-3
GO:0034969	histone arginine methylation	1.834227e-3
GO:0033326	cerebrospinal fluid secretion	1.836248e-3
GO:0033133	positive regulation of glucokinase activity	1.836248e-3
GO:0010985	negative regulation of lipoprotein particle clearance	1.842371e-3
GO:0070845	polyubiquitinated misfolded protein transport	1.859766e-3
GO:0002432	granuloma formation	1.859766e-3
GO:0015742	alpha-ketoglutarate transport	1.859766e-3
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	1.859766e-3
GO:0009443	pyridoxal 5'-phosphate salvage	1.859766e-3
GO:0055026	negative regulation of cardiac muscle tissue development	1.864094e-3
GO:0033209	tumor necrosis factor-mediated signaling pathway	1.882138e-3
GO:0071392	cellular response to estradiol stimulus	1.947941e-3
GO:0042149	cellular response to glucose starvation	1.948333e-3
GO:2000573	positive regulation of DNA biosynthetic process	1.973740e-3
GO:0046724	oxalic acid secretion	1.984083e-3
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	1.984083e-3
GO:0034968	histone lysine methylation	1.996041e-3
GO:0032780	negative regulation of ATPase activity	2.024420e-3
GO:0033159	negative regulation of protein import into nucleus, translocation	2.067066e-3
GO:0006556	S-adenosylmethionine biosynthetic process	2.067066e-3
GO:0051586	positive regulation of dopamine uptake	2.069183e-3
GO:0045355	negative regulation of interferon-alpha biosynthetic process	2.069183e-3
GO:0008624	induction of apoptosis by extracellular signals	2.138469e-3
GO:0060337	type I interferon-mediated signaling pathway	2.139867e-3
GO:0045351	type I interferon biosynthetic process	2.145654e-3
GO:0001578	microtubule bundle formation	2.158936e-3
GO:0009744	response to sucrose stimulus	2.222941e-3
GO:0071044	histone mRNA catabolic process	2.232865e-3
GO:0015858	nucleoside transport	2.246607e-3
GO:0033131	regulation of glucokinase activity	2.288035e-3
GO:0072060	outer medullary collecting duct development	2.344519e-3
GO:0072061	inner medullary collecting duct development	2.344519e-3
GO:0070943	neutrophil mediated killing of symbiont cell	2.344519e-3
GO:0051299	centrosome separation	2.344519e-3
GO:0009637	response to blue light	2.344519e-3
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	2.344519e-3
GO:0032754	positive regulation of interleukin-5 production	2.353803e-3
GO:0043313	regulation of neutrophil degranulation	2.362592e-3
GO:0071584	negative regulation of zinc ion import	2.410639e-3
GO:0090281	negative regulation of calcium ion import	2.410639e-3
GO:0071279	cellular response to cobalt ion	2.410639e-3
GO:0035803	egg coat formation	2.410639e-3
GO:0006203	dGTP catabolic process	2.410639e-3
GO:0010637	negative regulation of mitochondrial fusion	2.410639e-3
GO:0031102	neuron projection regeneration	2.467377e-3
GO:0043985	histone H4-R3 methylation	2.499486e-3
GO:0065001	specification of axis polarity	2.499486e-3
GO:0051764	actin crosslink formation	2.572509e-3
GO:0001955	blood vessel maturation	2.583195e-3
GO:0006012	galactose metabolic process	2.586943e-3
GO:0017004	cytochrome complex assembly	2.601127e-3
GO:0003406	retinal pigment epithelium development	2.601127e-3
GO:0032855	positive regulation of Rac GTPase activity	2.628804e-3
GO:0071299	cellular response to vitamin A	2.631531e-3
GO:0032387	negative regulation of intracellular transport	2.631672e-3
GO:0032200	telomere organization	2.642195e-3
GO:0022616	DNA strand elongation	2.657874e-3
GO:0035265	organ growth	2.707812e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	2.738709e-3
GO:0043462	regulation of ATPase activity	2.748639e-3
GO:0035414	negative regulation of catenin import into nucleus	2.753680e-3
GO:0000414	regulation of histone H3-K36 methylation	2.758462e-3
GO:0000154	rRNA modification	2.775312e-3
GO:0019320	hexose catabolic process	2.853863e-3
GO:0008628	induction of apoptosis by hormones	2.868792e-3
GO:0071218	cellular response to misfolded protein	2.878269e-3
GO:0032606	type I interferon production	2.878269e-3
GO:0033002	muscle cell proliferation	2.897477e-3
GO:0048702	embryonic neurocranium morphogenesis	2.912399e-3
GO:0032233	positive regulation of actin filament bundle assembly	2.984821e-3
GO:0090136	epithelial cell-cell adhesion	3.013363e-3
GO:0034959	endothelin maturation	3.015984e-3
GO:0010816	calcitonin catabolic process	3.015984e-3
GO:0010814	substance P catabolic process	3.015984e-3
GO:0035924	cellular response to vascular endothelial growth factor stimulus	3.037189e-3
GO:0001928	regulation of exocyst assembly	3.050161e-3
GO:0060178	regulation of exocyst localization	3.050161e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	3.070088e-3
GO:0034436	glycoprotein transport	3.094872e-3
GO:0009720	detection of hormone stimulus	3.094872e-3
GO:0072659	protein localization in plasma membrane	3.159282e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	3.187383e-3
GO:0002002	regulation of angiotensin levels in blood	3.205689e-3
GO:0065002	intracellular protein transmembrane transport	3.213603e-3
GO:0034340	response to type I interferon	3.233064e-3
GO:0006680	glucosylceramide catabolic process	3.282817e-3
GO:0070194	synaptonemal complex disassembly	3.385338e-3
GO:0046174	polyol catabolic process	3.385338e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	3.385338e-3
GO:0018125	peptidyl-cysteine methylation	3.463381e-3
GO:0010988	regulation of low-density lipoprotein particle clearance	3.463381e-3
GO:0033189	response to vitamin A	3.473493e-3
GO:0035520	monoubiquitinated protein deubiquitination	3.506033e-3
GO:0033504	floor plate development	3.555089e-3
GO:0032025	response to cobalt ion	3.555089e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	3.555089e-3
GO:0008633	activation of pro-apoptotic gene products	3.642188e-3
GO:0022009	central nervous system vasculogenesis	3.727447e-3
GO:0043534	blood vessel endothelial cell migration	3.732610e-3
GO:0031109	microtubule polymerization or depolymerization	3.736717e-3
GO:0044275	cellular carbohydrate catabolic process	3.825153e-3
GO:0014002	astrocyte development	3.831073e-3
GO:0090239	regulation of histone H4 acetylation	3.866909e-3
GO:0032506	cytokinetic process	3.866909e-3
GO:0060748	tertiary branching involved in mammary gland duct morphogenesis	3.877536e-3
GO:0050747	positive regulation of lipoprotein metabolic process	3.915101e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	3.921297e-3
GO:0032530	regulation of microvillus organization	3.939209e-3
GO:0072110	glomerular mesangial cell proliferation	3.939209e-3
GO:0006562	proline catabolic process	3.957099e-3
GO:0021562	vestibulocochlear nerve development	3.968357e-3
GO:0007217	tachykinin receptor signaling pathway	3.970213e-3
GO:0051572	negative regulation of histone H3-K4 methylation	3.973105e-3
GO:0090241	negative regulation of histone H4 acetylation	3.973105e-3
GO:0031297	replication fork processing	4.008222e-3
GO:0042304	regulation of fatty acid biosynthetic process	4.109146e-3
GO:0061014	positive regulation of mRNA catabolic process	4.181824e-3
GO:0061013	regulation of mRNA catabolic process	4.279589e-3
GO:0048793	pronephros development	4.302525e-3
GO:0030704	vitelline membrane formation	4.342153e-3
GO:0009098	leucine biosynthetic process	4.342153e-3
GO:0006550	isoleucine catabolic process	4.342153e-3
GO:0060253	negative regulation of glial cell proliferation	4.351389e-3
GO:0002904	positive regulation of B cell apoptosis	4.352071e-3
GO:0032864	activation of Cdc42 GTPase activity	4.507233e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	4.533997e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	4.533997e-3
GO:0002074	extraocular skeletal muscle development	4.533997e-3
GO:0071529	cementum mineralization	4.533997e-3
GO:0010940	positive regulation of necrotic cell death	4.576690e-3
GO:0042308	negative regulation of protein import into nucleus	4.593641e-3
GO:0046390	ribose phosphate biosynthetic process	4.614213e-3
GO:0032534	regulation of microvillus assembly	4.614213e-3
GO:0032464	positive regulation of protein homooligomerization	4.629490e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	4.641029e-3
GO:0022011	myelination in peripheral nervous system	4.648299e-3
GO:0035307	positive regulation of protein dephosphorylation	4.654141e-3
GO:0009069	serine family amino acid metabolic process	4.662014e-3
GO:0016570	histone modification	4.714246e-3
GO:0032526	response to retinoic acid	4.717691e-3
GO:0007216	metabotropic glutamate receptor signaling pathway	4.836156e-3
GO:2000467	positive regulation of glycogen (starch) synthase activity	4.852977e-3
GO:0006734	NADH metabolic process	4.928729e-3
GO:0071474	cellular hyperosmotic response	4.965425e-3
GO:0051154	negative regulation of striated muscle cell differentiation	4.966021e-3
GO:0043647	inositol phosphate metabolic process	4.984499e-3
GO:0015709	thiosulfate transport	5.003660e-3
GO:0071423	malate transmembrane transport	5.003660e-3
GO:0006559	L-phenylalanine catabolic process	5.033040e-3
GO:0006244	pyrimidine nucleotide catabolic process	5.151734e-3
GO:0015870	acetylcholine transport	5.160938e-3
GO:0070947	neutrophil mediated killing of fungus	5.165542e-3
GO:0070286	axonemal dynein complex assembly	5.165542e-3
GO:0061144	alveolar secondary septum development	5.226962e-3
GO:2000491	positive regulation of hepatic stellate cell activation	5.226962e-3
GO:0034766	negative regulation of ion transmembrane transport	5.226962e-3
GO:0002418	immune response to tumor cell	5.226962e-3
GO:0033505	floor plate morphogenesis	5.237977e-3
GO:0043501	skeletal muscle adaptation	5.262695e-3
GO:0007009	plasma membrane organization	5.361849e-3
GO:0046513	ceramide biosynthetic process	5.552962e-3
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	5.598482e-3
GO:0060754	positive regulation of mast cell chemotaxis	5.717459e-3
GO:0032836	glomerular basement membrane development	5.717459e-3
GO:0006665	sphingolipid metabolic process	5.717633e-3
GO:0006059	hexitol metabolic process	5.845407e-3
GO:0046364	monosaccharide biosynthetic process	5.991909e-3
GO:0009313	oligosaccharide catabolic process	6.022038e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	6.040462e-3
GO:0035306	positive regulation of dephosphorylation	6.040462e-3
GO:0046434	organophosphate catabolic process	6.058973e-3
GO:0010939	regulation of necrotic cell death	6.079529e-3
GO:0035304	regulation of protein dephosphorylation	6.128197e-3
GO:0032525	somite rostral/caudal axis specification	6.180649e-3
GO:0021523	somatic motor neuron differentiation	6.196140e-3
GO:0006740	NADPH regeneration	6.204967e-3
GO:0030237	female sex determination	6.278008e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	6.311423e-3
GO:0018993	somatic sex determination	6.341331e-3
GO:0051492	regulation of stress fiber assembly	6.413949e-3
GO:0045657	positive regulation of monocyte differentiation	6.421248e-3
GO:0015879	carnitine transport	6.541377e-3
GO:0042758	long-chain fatty acid catabolic process	6.575989e-3
GO:0042413	carnitine catabolic process	6.575989e-3
GO:0006273	lagging strand elongation	6.575989e-3
GO:0009992	cellular water homeostasis	6.590304e-3
GO:0007379	segment specification	6.602133e-3
GO:0016575	histone deacetylation	6.660891e-3
GO:0046365	monosaccharide catabolic process	6.681987e-3
GO:0071731	response to nitric oxide	6.726693e-3
GO:0031064	negative regulation of histone deacetylation	6.956930e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	6.956930e-3
GO:0035967	cellular response to topologically incorrect protein	7.041332e-3
GO:0032321	positive regulation of Rho GTPase activity	7.229045e-3
GO:0009226	nucleotide-sugar biosynthetic process	7.261954e-3
GO:0060263	regulation of respiratory burst	7.275863e-3
GO:0006546	glycine catabolic process	7.319914e-3
GO:0060972	left/right pattern formation	7.319914e-3
GO:0010896	regulation of triglyceride catabolic process	7.319914e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	7.324860e-3
GO:0045819	positive regulation of glycogen catabolic process	7.324860e-3
GO:0061360	optic chiasma development	7.328264e-3
GO:0035799	ureter maturation	7.328264e-3
GO:2000597	positive regulation of optic nerve formation	7.328264e-3
GO:0021650	vestibulocochlear nerve formation	7.328264e-3
GO:0021633	optic nerve structural organization	7.328264e-3
GO:0014034	neural crest cell fate commitment	7.385074e-3
GO:0019048	virus-host interaction	7.553003e-3
GO:0072044	collecting duct development	7.663622e-3
GO:0006930	substrate-dependent cell migration, cell extension	7.669992e-3
GO:0021528	commissural neuron differentiation in spinal cord	7.775422e-3
GO:0035364	thymine transport	7.775422e-3
GO:0035344	hypoxanthine transport	7.775422e-3
GO:0015854	guanine transport	7.775422e-3
GO:0010836	negative regulation of protein ADP-ribosylation	7.775422e-3
GO:0032459	regulation of protein oligomerization	7.883320e-3
GO:0001300	chronological cell aging	7.970006e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	7.995939e-3
GO:0030213	hyaluronan biosynthetic process	8.055798e-3
GO:0090181	regulation of cholesterol metabolic process	8.097874e-3
GO:0010832	negative regulation of myotube differentiation	8.153784e-3
GO:0042823	pyridoxal phosphate biosynthetic process	8.197223e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	8.282885e-3
GO:0006264	mitochondrial DNA replication	8.511242e-3
GO:0015893	drug transport	8.527994e-3
GO:0021678	third ventricle development	8.547221e-3
GO:0072162	metanephric mesenchymal cell differentiation	8.567963e-3
GO:0008156	negative regulation of DNA replication	8.649155e-3
GO:0061301	cerebellum vasculature morphogenesis	8.652768e-3
GO:0046951	ketone body biosynthetic process	8.655333e-3
GO:0070079	histone H4-R3 demethylation	8.674750e-3
GO:0070078	histone H3-R2 demethylation	8.674750e-3
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	8.674750e-3
GO:0061143	alveolar primary septum development	8.674750e-3
GO:0003383	apical constriction	8.674750e-3
GO:0072086	specification of loop of Henle identity	8.681708e-3
GO:0061302	smooth muscle cell-matrix adhesion	8.885198e-3
GO:0051937	catecholamine transport	8.939841e-3
GO:0046950	cellular ketone body metabolic process	8.986282e-3
GO:0019322	pentose biosynthetic process	8.994734e-3
GO:0006268	DNA unwinding involved in replication	8.994734e-3
GO:0000917	barrier septum formation	9.037234e-3
GO:0032218	riboflavin transport	9.037234e-3
GO:0070926	regulation of ATP:ADP antiporter activity	9.037234e-3
GO:0006499	N-terminal protein myristoylation	9.037234e-3
GO:0003264	regulation of cardioblast proliferation	9.054741e-3
GO:0070141	response to UV-A	9.237421e-3
GO:0072385	minus-end-directed organelle transport along microtubule	9.296299e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	9.359197e-3
GO:0070314	G1 to G0 transition	9.500102e-3
GO:0032383	regulation of intracellular cholesterol transport	9.500102e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0033239	negative regulation of cellular amine metabolic process	4.303882e-8
GO:0002268	follicular dendritic cell differentiation	4.919309e-8
GO:0009082	branched chain family amino acid biosynthetic process	4.972615e-8
GO:0031440	regulation of mRNA 3'-end processing	1.201569e-7
GO:0031442	positive regulation of mRNA 3'-end processing	1.589239e-7
GO:0021681	cerebellar granular layer development	4.163677e-7
GO:0061014	positive regulation of mRNA catabolic process	4.205991e-7
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.228154e-6
GO:0030865	cortical cytoskeleton organization	1.574995e-6
GO:0010900	negative regulation of phosphatidylcholine catabolic process	2.236262e-6
GO:0009912	auditory receptor cell fate commitment	3.466724e-6
GO:0006342	chromatin silencing	3.877583e-6
GO:0045814	negative regulation of gene expression, epigenetic	4.192140e-6
GO:0032479	regulation of type I interferon production	6.594253e-6
GO:0010424	DNA methylation on cytosine within a CG sequence	7.788595e-6
GO:0032375	negative regulation of cholesterol transport	7.868154e-6
GO:0046499	S-adenosylmethioninamine metabolic process	9.785290e-6
GO:0030866	cortical actin cytoskeleton organization	1.003500e-5
GO:0032481	positive regulation of type I interferon production	1.320447e-5
GO:0032012	regulation of ARF protein signal transduction	1.386323e-5
GO:0050995	negative regulation of lipid catabolic process	1.775469e-5
GO:0010388	cullin deneddylation	1.809123e-5
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.335103e-5
GO:0006779	porphyrin-containing compound biosynthetic process	2.502777e-5
GO:0046498	S-adenosylhomocysteine metabolic process	2.665386e-5
GO:0021707	cerebellar granule cell differentiation	3.506212e-5
GO:0045079	negative regulation of chemokine biosynthetic process	3.743816e-5
GO:0045922	negative regulation of fatty acid metabolic process	4.591411e-5
GO:0010985	negative regulation of lipoprotein particle clearance	4.685215e-5
GO:0021683	cerebellar granular layer morphogenesis	4.794083e-5
GO:0032922	circadian regulation of gene expression	5.003219e-5
GO:0010288	response to lead ion	5.383565e-5
GO:0043985	histone H4-R3 methylation	6.487961e-5
GO:0043951	negative regulation of cAMP-mediated signaling	6.487961e-5
GO:0006476	protein deacetylation	7.503516e-5
GO:0010984	regulation of lipoprotein particle clearance	8.265930e-5
GO:0051583	dopamine uptake	9.011000e-5
GO:0032099	negative regulation of appetite	9.498864e-5
GO:0035601	protein deacylation	1.185306e-4
GO:0032776	DNA methylation on cytosine	1.220780e-4
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.224008e-4
GO:0010887	negative regulation of cholesterol storage	1.224175e-4
GO:0072593	reactive oxygen species metabolic process	1.750731e-4
GO:2000974	negative regulation of pro-B cell differentiation	1.804324e-4
GO:0032096	negative regulation of response to food	1.804324e-4
GO:0019048	virus-host interaction	1.921257e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.928930e-4
GO:0032648	regulation of interferon-beta production	2.001332e-4
GO:0090141	positive regulation of mitochondrial fission	2.027894e-4
GO:0050685	positive regulation of mRNA processing	2.060784e-4
GO:0060696	regulation of phospholipid catabolic process	2.087767e-4
GO:0070141	response to UV-A	2.156064e-4
GO:0043949	regulation of cAMP-mediated signaling	2.349456e-4
GO:0060709	glycogen cell development involved in embryonic placenta development	2.809622e-4
GO:0051005	negative regulation of lipoprotein lipase activity	3.071103e-4
GO:0034382	chylomicron remnant clearance	3.071103e-4
GO:0021526	medial motor column neuron differentiation	3.605396e-4
GO:0002642	positive regulation of immunoglobulin biosynthetic process	3.605396e-4
GO:0031507	heterochromatin formation	3.684531e-4
GO:0000387	spliceosomal snRNP assembly	4.024582e-4
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	4.154723e-4
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	4.154723e-4
GO:0018023	peptidyl-lysine trimethylation	4.423886e-4
GO:0033238	regulation of cellular amine metabolic process	4.553760e-4
GO:2000774	positive regulation of cellular senescence	4.929202e-4
GO:0090402	oncogene-induced senescence	4.929202e-4
GO:0035986	senescence-associated heterochromatin focus formation	4.929202e-4
GO:0070078	histone H3-R2 demethylation	5.270460e-4
GO:0070079	histone H4-R3 demethylation	5.270460e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	5.270460e-4
GO:0014909	smooth muscle cell migration	5.293195e-4
GO:0008334	histone mRNA metabolic process	5.503032e-4
GO:0007221	positive regulation of transcription of Notch receptor target	5.601145e-4
GO:0061013	regulation of mRNA catabolic process	5.782183e-4
GO:0035095	behavioral response to nicotine	5.903418e-4
GO:0019344	cysteine biosynthetic process	5.903418e-4
GO:0007000	nucleolus organization	5.903418e-4
GO:0010822	positive regulation of mitochondrion organization	6.008927e-4
GO:0000072	M phase specific microtubule process	6.277836e-4
GO:0033119	negative regulation of RNA splicing	6.406766e-4
GO:0032020	ISG15-protein conjugation	6.453402e-4
GO:0006646	phosphatidylethanolamine biosynthetic process	6.506172e-4
GO:0021892	cerebral cortex GABAergic interneuron differentiation	6.528857e-4
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	7.317247e-4
GO:0016575	histone deacetylation	7.354735e-4
GO:0043525	positive regulation of neuron apoptosis	8.281288e-4
GO:0046882	negative regulation of follicle-stimulating hormone secretion	8.534000e-4
GO:0034637	cellular carbohydrate biosynthetic process	8.635989e-4
GO:2000210	positive regulation of anoikis	9.486503e-4
GO:0090140	regulation of mitochondrial fission	9.596332e-4
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	9.596332e-4
GO:0090116	C-5 methylation of cytosine	9.736278e-4
GO:0030325	adrenal gland development	9.746428e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	9.860168e-4
GO:0061302	smooth muscle cell-matrix adhesion	9.886574e-4
GO:0048570	notochord morphogenesis	1.088748e-3
GO:0042743	hydrogen peroxide metabolic process	1.097462e-3
GO:0031914	negative regulation of synaptic plasticity	1.128847e-3
GO:0030421	defecation	1.128847e-3
GO:0070925	organelle assembly	1.192240e-3
GO:0071593	lymphocyte aggregation	1.203693e-3
GO:0035435	phosphate ion transmembrane transport	1.203693e-3
GO:0032536	regulation of cell projection size	1.203931e-3
GO:0033692	cellular polysaccharide biosynthetic process	1.239939e-3
GO:0010721	negative regulation of cell development	1.241893e-3
GO:0045948	positive regulation of translational initiation	1.301500e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	1.319696e-3
GO:0072144	glomerular mesangial cell development	1.335569e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.335569e-3
GO:0002051	osteoblast fate commitment	1.351298e-3
GO:0090169	regulation of spindle assembly	1.367815e-3
GO:0090234	regulation of kinetochore assembly	1.367815e-3
GO:0006344	maintenance of chromatin silencing	1.405950e-3
GO:0048663	neuron fate commitment	1.417123e-3
GO:0009411	response to UV	1.486452e-3
GO:0031133	regulation of axon diameter	1.498386e-3
GO:0006749	glutathione metabolic process	1.519197e-3
GO:0032108	negative regulation of response to nutrient levels	1.589092e-3
GO:0072044	collecting duct development	1.604118e-3
GO:0045806	negative regulation of endocytosis	1.609121e-3
GO:0046847	filopodium assembly	1.618036e-3
GO:0032933	SREBP-mediated signaling pathway	1.622222e-3
GO:2000772	regulation of cellular senescence	1.626306e-3
GO:0043654	recognition of apoptotic cell	1.653506e-3
GO:0043276	anoikis	1.683892e-3
GO:0007386	compartment pattern specification	1.683892e-3
GO:0042552	myelination	1.701281e-3
GO:0032095	regulation of response to food	1.768987e-3
GO:0009070	serine family amino acid biosynthetic process	1.793584e-3
GO:0048148	behavioral response to cocaine	1.817278e-3
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	1.968320e-3
GO:0051586	positive regulation of dopamine uptake	1.968320e-3
GO:0014719	satellite cell activation	1.968320e-3
GO:0015732	prostaglandin transport	1.986375e-3
GO:0045833	negative regulation of lipid metabolic process	2.014607e-3
GO:2000143	negative regulation of transcription initiation, DNA-dependent	2.177678e-3
GO:0010821	regulation of mitochondrion organization	2.241223e-3
GO:0032728	positive regulation of interferon-beta production	2.253517e-3
GO:0071218	cellular response to misfolded protein	2.258192e-3
GO:0010936	negative regulation of macrophage cytokine production	2.258192e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	2.298229e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	2.298229e-3
GO:0051835	positive regulation of synapse structural plasticity	2.298229e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	2.298229e-3
GO:0045647	negative regulation of erythrocyte differentiation	2.612328e-3
GO:0048627	myoblast development	2.727892e-3
GO:0045415	negative regulation of interleukin-8 biosynthetic process	2.727892e-3
GO:0022601	menstrual cycle phase	2.807251e-3
GO:0046329	negative regulation of JNK cascade	2.810016e-3
GO:0003032	detection of oxygen	2.823577e-3
GO:0051865	protein autoubiquitination	2.842935e-3
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	3.030201e-3
GO:0048710	regulation of astrocyte differentiation	3.049061e-3
GO:0006997	nucleus organization	3.097094e-3
GO:0005978	glycogen biosynthetic process	3.115495e-3
GO:0051823	regulation of synapse structural plasticity	3.160891e-3
GO:0015780	nucleotide-sugar transport	3.160891e-3
GO:0006783	heme biosynthetic process	3.186223e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.197753e-3
GO:0006467	protein thiol-disulfide exchange	3.383382e-3
GO:0051026	chiasma assembly	3.405777e-3
GO:0060167	regulation of adenosine receptor signaling pathway	3.445545e-3
GO:0070563	negative regulation of vitamin D receptor signaling pathway	3.478809e-3
GO:2000647	negative regulation of stem cell proliferation	3.478809e-3
GO:0046108	uridine metabolic process	3.478809e-3
GO:0010839	negative regulation of keratinocyte proliferation	3.478809e-3
GO:0035921	desmosome disassembly	3.478809e-3
GO:0046373	L-arabinose metabolic process	3.480051e-3
GO:0010845	positive regulation of reciprocal meiotic recombination	3.480051e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	3.495006e-3
GO:0007418	ventral midline development	3.495006e-3
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	3.495006e-3
GO:0022038	corpus callosum development	3.727961e-3
GO:0009069	serine family amino acid metabolic process	3.782192e-3
GO:0010869	regulation of receptor biosynthetic process	3.791573e-3
GO:0046128	purine ribonucleoside metabolic process	3.833925e-3
GO:0042278	purine nucleoside metabolic process	3.849461e-3
GO:0006657	CDP-choline pathway	3.871677e-3
GO:0046015	regulation of transcription by glucose	3.871677e-3
GO:0072109	glomerular mesangium development	3.891981e-3
GO:0048702	embryonic neurocranium morphogenesis	3.891981e-3
GO:0008366	axon ensheathment	4.005352e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	4.065353e-3
GO:0071157	negative regulation of cell cycle arrest	4.159961e-3
GO:0032606	type I interferon production	4.159961e-3
GO:0006984	ER-nucleus signaling pathway	4.189102e-3
GO:0050768	negative regulation of neurogenesis	4.304953e-3
GO:0032465	regulation of cytokinesis	4.488413e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	4.561335e-3
GO:0007051	spindle organization	4.708170e-3
GO:0016926	protein desumoylation	4.732402e-3
GO:0032796	uropod organization	4.732402e-3
GO:0060124	positive regulation of growth hormone secretion	4.797246e-3
GO:0016032	viral reproduction	4.864806e-3
GO:0033627	cell adhesion mediated by integrin	4.947202e-3
GO:0030035	microspike assembly	5.009282e-3
GO:0034498	early endosome to Golgi transport	5.158052e-3
GO:0010034	response to acetate	5.158052e-3
GO:0033522	histone H2A ubiquitination	5.244558e-3
GO:0035414	negative regulation of catenin import into nucleus	5.261334e-3
GO:0046501	protoporphyrinogen IX metabolic process	5.409141e-3
GO:0035444	nickel ion transmembrane transport	5.420764e-3
GO:0031999	negative regulation of fatty acid beta-oxidation	5.420764e-3
GO:0006094	gluconeogenesis	5.761263e-3
GO:0006446	regulation of translational initiation	5.794265e-3
GO:0048840	otolith development	5.812462e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	5.812462e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	5.902432e-3
GO:0021877	forebrain neuron fate commitment	5.948452e-3
GO:0045606	positive regulation of epidermal cell differentiation	6.030401e-3
GO:0042668	auditory receptor cell fate determination	6.030401e-3
GO:0050689	negative regulation of defense response to virus by host	6.066383e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	6.066383e-3
GO:0015781	pyrimidine nucleotide-sugar transport	6.066383e-3
GO:0032927	positive regulation of activin receptor signaling pathway	6.066383e-3
GO:0000917	barrier septum formation	6.066383e-3
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	6.066383e-3
GO:0000722	telomere maintenance via recombination	6.066383e-3
GO:0071870	cellular response to catecholamine stimulus	6.108877e-3
GO:0009141	nucleoside triphosphate metabolic process	6.128461e-3
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	6.353543e-3
GO:0050928	negative regulation of positive chemotaxis	6.525565e-3
GO:0070086	ubiquitin-dependent endocytosis	6.525565e-3
GO:0090324	negative regulation of oxidative phosphorylation	6.525565e-3
GO:0048790	maintenance of presynaptic active zone structure	6.525565e-3
GO:0032782	bile acid secretion	6.525565e-3
GO:0003096	renal sodium ion transport	6.525565e-3
GO:0044140	negative regulation of growth of symbiont on or near host surface	6.525565e-3
GO:0010255	glucose mediated signaling pathway	6.525565e-3
GO:0035470	positive regulation of vascular wound healing	6.525565e-3
GO:0060674	placenta blood vessel development	6.551976e-3
GO:0043046	DNA methylation involved in gamete generation	6.872696e-3
GO:0046784	intronless viral mRNA export from host nucleus	6.990345e-3
GO:0007141	male meiosis I	6.990345e-3
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	7.427274e-3
GO:0032418	lysosome localization	7.427274e-3
GO:0014807	regulation of somitogenesis	7.427274e-3
GO:0097150	neuronal stem cell maintenance	7.452016e-3
GO:0031167	rRNA methylation	7.452016e-3
GO:0009144	purine nucleoside triphosphate metabolic process	7.464705e-3
GO:0006575	cellular modified amino acid metabolic process	7.472368e-3
GO:0021587	cerebellum morphogenesis	7.529175e-3
GO:0045796	negative regulation of intestinal cholesterol absorption	7.560304e-3
GO:0045110	intermediate filament bundle assembly	7.560304e-3
GO:0060168	positive regulation of adenosine receptor signaling pathway	7.560304e-3
GO:0071206	establishment of protein localization to juxtaparanode region of axon	7.560304e-3
GO:0050668	positive regulation of homocysteine metabolic process	7.560304e-3
GO:0045963	negative regulation of dopamine metabolic process	7.560304e-3
GO:0006437	tyrosyl-tRNA aminoacylation	7.560304e-3
GO:0035419	activation of MAPK activity involved in innate immune response	7.560304e-3
GO:0010949	negative regulation of intestinal phytosterol absorption	7.560304e-3
GO:0034421	post-translational protein acetylation	7.560304e-3
GO:0021979	hypothalamus cell differentiation	7.560304e-3
GO:0009199	ribonucleoside triphosphate metabolic process	7.588195e-3
GO:0007044	cell-substrate junction assembly	7.685919e-3
GO:0060712	spongiotrophoblast layer development	7.837794e-3
GO:0021575	hindbrain morphogenesis	7.842135e-3
GO:0006398	histone mRNA 3'-end processing	7.899873e-3
GO:0035441	cell migration involved in vasculogenesis	7.899873e-3
GO:0090209	negative regulation of triglyceride metabolic process	7.917353e-3
GO:0051055	negative regulation of lipid biosynthetic process	7.962984e-3
GO:0071874	cellular response to norepinephrine stimulus	7.990789e-3
GO:0008643	carbohydrate transport	8.172890e-3
GO:0033085	negative regulation of T cell differentiation in thymus	8.233389e-3
GO:0008356	asymmetric cell division	8.249515e-3
GO:0006705	mineralocorticoid biosynthetic process	8.249515e-3
GO:0035520	monoubiquitinated protein deubiquitination	8.254645e-3
GO:0043932	ossification involved in bone remodeling	8.260678e-3
GO:0015793	glycerol transport	8.260678e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	8.260678e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	8.260678e-3
GO:0006184	GTP catabolic process	8.317450e-3
GO:2000981	negative regulation of inner ear receptor cell differentiation	8.329435e-3
GO:0060192	negative regulation of lipase activity	8.342401e-3
GO:0030513	positive regulation of BMP signaling pathway	8.382339e-3
GO:0051901	positive regulation of mitochondrial depolarization	8.405602e-3
GO:0060032	notochord regression	8.422841e-3
GO:0009205	purine ribonucleoside triphosphate metabolic process	8.562790e-3
GO:0007131	reciprocal meiotic recombination	8.660198e-3
GO:0009150	purine ribonucleotide metabolic process	8.681728e-3
GO:0007258	JUN phosphorylation	8.696966e-3
GO:0007352	zygotic specification of dorsal/ventral axis	9.096814e-3
GO:0035412	regulation of catenin import into nucleus	9.129495e-3
GO:0044030	regulation of DNA methylation	9.177274e-3
GO:0010870	positive regulation of receptor biosynthetic process	9.323050e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	9.323050e-3
GO:0045687	positive regulation of glial cell differentiation	9.460166e-3
GO:0007032	endosome organization	9.524366e-3
GO:0048711	positive regulation of astrocyte differentiation	9.618395e-3
GO:0032098	regulation of appetite	9.748841e-3
GO:0003219	cardiac right ventricle formation	9.751912e-3
GO:0043045	DNA methylation involved in embryo development	9.979463e-3
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	9.979463e-3
GO:0018342	protein prenylation	9.979463e-3
GO:0048664	neuron fate determination	1.007389e-2
GO:0015824	proline transport	1.007389e-2
GO:0000725	recombinational repair	1.008398e-2
GO:0000060	protein import into nucleus, translocation	1.008923e-2
GO:0007143	female meiosis	1.017819e-2
GO:0009650	UV protection	1.019015e-2
GO:0032319	regulation of Rho GTPase activity	1.031161e-2
GO:0000212	meiotic spindle organization	1.041847e-2
GO:0051956	negative regulation of amino acid transport	1.041847e-2
GO:0032321	positive regulation of Rho GTPase activity	1.049375e-2
GO:0032218	riboflavin transport	1.051354e-2
GO:0006235	dTTP biosynthetic process	1.051354e-2
GO:0072143	mesangial cell development	1.074764e-2
GO:0070584	mitochondrion morphogenesis	1.074764e-2
GO:0022411	cellular component disassembly	1.077575e-2
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1.085330e-2
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	1.116550e-2
GO:0006195	purine nucleotide catabolic process	1.118154e-2
GO:0042744	hydrogen peroxide catabolic process	1.128048e-2
GO:0042398	cellular modified amino acid biosynthetic process	1.136819e-2
GO:0034447	very-low-density lipoprotein particle clearance	1.156624e-2
GO:0042420	dopamine catabolic process	1.161810e-2
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.161810e-2
GO:0006281	DNA repair	1.162905e-2
GO:0030505	inorganic diphosphate transport	1.172878e-2
GO:0032008	positive regulation of TOR signaling cascade	1.190710e-2
GO:0055075	potassium ion homeostasis	1.215542e-2
GO:0035524	proline transmembrane transport	1.215542e-2
GO:0051220	cytoplasmic sequestering of protein	1.222510e-2
GO:0010871	negative regulation of receptor biosynthetic process	1.222510e-2
GO:0008652	cellular amino acid biosynthetic process	1.223328e-2
GO:0021682	nerve maturation	1.224059e-2
GO:0030311	poly-N-acetyllactosamine biosynthetic process	1.224059e-2
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.224059e-2
GO:0019047	provirus integration	1.224059e-2
GO:0045575	basophil activation	1.224059e-2
GO:0006256	UDP catabolic process	1.224059e-2
GO:0010996	response to auditory stimulus	1.224059e-2
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.224059e-2
GO:0018344	protein geranylgeranylation	1.224059e-2
GO:0072337	modified amino acid transport	1.235805e-2
GO:0071845	cellular component disassembly at cellular level	1.243488e-2
GO:0090045	positive regulation of deacetylase activity	1.244211e-2
GO:0002077	acrosome matrix dispersal	1.244211e-2
GO:0051292	nuclear pore complex assembly	1.247808e-2
GO:0009051	pentose-phosphate shunt, oxidative branch	1.247808e-2
GO:0071577	zinc ion transmembrane transport	1.264649e-2
GO:0051764	actin crosslink formation	1.265888e-2
GO:2000171	negative regulation of dendrite development	1.291960e-2
GO:0006999	nuclear pore organization	1.297407e-2
GO:0042697	menopause	1.299925e-2
GO:0072076	nephrogenic mesenchyme development	1.299925e-2
GO:0072539	T-helper 17 cell differentiation	1.299925e-2
GO:0018243	protein O-linked glycosylation via threonine	1.299925e-2
GO:0032799	low-density lipoprotein receptor particle metabolic process	1.299925e-2
GO:0002155	regulation of thyroid hormone mediated signaling pathway	1.299925e-2
GO:0018242	protein O-linked glycosylation via serine	1.299925e-2
GO:0045651	positive regulation of macrophage differentiation	1.309520e-2
GO:0033590	response to cobalamin	1.309520e-2
GO:0008625	induction of apoptosis via death domain receptors	1.311177e-2
GO:0071044	histone mRNA catabolic process	1.317356e-2
GO:0006700	C21-steroid hormone biosynthetic process	1.336311e-2
GO:0045084	positive regulation of interleukin-12 biosynthetic process	1.347422e-2
GO:0009152	purine ribonucleotide biosynthetic process	1.359785e-2
GO:0043503	skeletal muscle fiber adaptation	1.374859e-2
GO:0006264	mitochondrial DNA replication	1.374859e-2
GO:0032277	negative regulation of gonadotropin secretion	1.431253e-2
GO:0001893	maternal placenta development	1.439958e-2
GO:0046039	GTP metabolic process	1.440687e-2
GO:0009071	serine family amino acid catabolic process	1.448444e-2
GO:0060669	embryonic placenta morphogenesis	1.450167e-2
GO:0072521	purine-containing compound metabolic process	1.450451e-2
GO:0009146	purine nucleoside triphosphate catabolic process	1.460654e-2
GO:0033327	Leydig cell differentiation	1.462058e-2
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.472605e-2
GO:2000980	regulation of inner ear receptor cell differentiation	1.473612e-2
GO:0015758	glucose transport	1.533277e-2
GO:0060706	cell differentiation involved in embryonic placenta development	1.540561e-2
GO:0051289	protein homotetramerization	1.553970e-2
GO:0021696	cerebellar cortex morphogenesis	1.554049e-2
GO:0021999	neural plate anterior/posterior regionalization	1.555067e-2
GO:0009309	amine biosynthetic process	1.563846e-2
GO:0097039	protein linear polyubiquitination	1.577287e-2
GO:0031427	response to methotrexate	1.577287e-2
GO:0045686	negative regulation of glial cell differentiation	1.615406e-2
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	1.622932e-2
GO:0014060	regulation of epinephrine secretion	1.622932e-2
GO:0048672	positive regulation of collateral sprouting	1.622932e-2
GO:0035967	cellular response to topologically incorrect protein	1.659654e-2
GO:0006778	porphyrin-containing compound metabolic process	1.672906e-2
GO:0050771	negative regulation of axonogenesis	1.692549e-2
GO:0090076	relaxation of skeletal muscle	1.697582e-2
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	1.697582e-2
GO:0022010	central nervous system myelination	1.702738e-2
GO:0030719	P granule organization	1.725374e-2
GO:0046654	tetrahydrofolate biosynthetic process	1.725374e-2
GO:0043201	response to leucine	1.725374e-2
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.725374e-2
GO:0000395	nuclear mRNA 5'-splice site recognition	1.725374e-2
GO:0045908	negative regulation of vasodilation	1.758741e-2
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.758741e-2
GO:0002230	positive regulation of defense response to virus by host	1.758741e-2
GO:0009143	nucleoside triphosphate catabolic process	1.805765e-2
GO:0040040	thermosensory behavior	1.809709e-2
GO:0097029	mature dendritic cell differentiation	1.809709e-2
GO:0071280	cellular response to copper ion	1.809709e-2
GO:0014028	notochord formation	1.809709e-2
GO:0006550	isoleucine catabolic process	1.809709e-2
GO:0009098	leucine biosynthetic process	1.809709e-2
GO:0000045	autophagic vacuole assembly	1.815201e-2
GO:0042696	menarche	1.819243e-2
GO:0046129	purine ribonucleoside biosynthetic process	1.822356e-2
GO:0032863	activation of Rac GTPase activity	1.825668e-2
GO:0000154	rRNA modification	1.849532e-2
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	1.866942e-2
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway	1.866942e-2
GO:0046415	urate metabolic process	1.869662e-2
GO:0040019	positive regulation of embryonic development	1.873238e-2
GO:0003254	regulation of membrane depolarization	1.896976e-2
GO:0071480	cellular response to gamma radiation	1.901605e-2
GO:0007183	SMAD protein complex assembly	1.901605e-2
GO:0051323	metaphase	1.904689e-2
GO:0007288	sperm axoneme assembly	1.904689e-2
GO:0006924	activation-induced cell death of T cells	1.937368e-2
GO:0031122	cytoplasmic microtubule organization	1.938962e-2
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.956949e-2
GO:0060457	negative regulation of digestive system process	1.986687e-2
GO:0070483	detection of hypoxia	1.986687e-2
GO:0031643	positive regulation of myelination	1.986687e-2
GO:0033128	negative regulation of histone phosphorylation	1.986687e-2
GO:0006434	seryl-tRNA aminoacylation	1.986687e-2
GO:0007089	traversing start control point of mitotic cell cycle	1.986687e-2
GO:0006420	arginyl-tRNA aminoacylation	1.986687e-2
GO:0009207	purine ribonucleoside triphosphate catabolic process	1.995595e-2
GO:0046513	ceramide biosynthetic process	2.000683e-2
GO:0032288	myelin assembly	2.001563e-2
GO:0045075	regulation of interleukin-12 biosynthetic process	2.001563e-2
GO:0045626	negative regulation of T-helper 1 cell differentiation	2.029121e-2
GO:0072134	nephrogenic mesenchyme morphogenesis	2.029121e-2
GO:0021985	neurohypophysis development	2.029121e-2
GO:0018993	somatic sex determination	2.029121e-2
GO:0043461	proton-transporting ATP synthase complex assembly	2.034314e-2
GO:0008637	apoptotic mitochondrial changes	2.043074e-2
GO:0046102	inosine metabolic process	2.057282e-2
GO:0006782	protoporphyrinogen IX biosynthetic process	2.057282e-2
GO:0030042	actin filament depolymerization	2.057282e-2
GO:0043011	myeloid dendritic cell differentiation	2.063522e-2
GO:0002238	response to molecule of fungal origin	2.072708e-2
GO:0045684	positive regulation of epidermis development	2.098720e-2
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	2.100548e-2
GO:0071777	positive regulation of cell cycle cytokinesis	2.122180e-2
GO:0051693	actin filament capping	2.139916e-2
GO:0016458	gene silencing	2.162272e-2
GO:0051567	histone H3-K9 methylation	2.163097e-2
GO:0048242	epinephrine secretion	2.167709e-2
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.200358e-2
GO:2000278	regulation of DNA biosynthetic process	2.222978e-2
GO:0021759	globus pallidus development	2.247656e-2
GO:0015760	glucose-6-phosphate transport	2.247656e-2
GO:0048133	male germ-line stem cell division	2.266852e-2
GO:0043402	glucocorticoid mediated signaling pathway	2.266852e-2
GO:0007412	axon target recognition	2.266852e-2
GO:0035021	negative regulation of Rac protein signal transduction	2.266852e-2
GO:0042306	regulation of protein import into nucleus	2.281344e-2
GO:0043252	sodium-independent organic anion transport	2.296060e-2
GO:0021528	commissural neuron differentiation in spinal cord	2.296060e-2
GO:0002561	basophil degranulation	2.296060e-2
GO:0010225	response to UV-C	2.304414e-2
GO:0010761	fibroblast migration	2.320119e-2
GO:0007440	foregut morphogenesis	2.331898e-2
GO:0042755	eating behavior	2.340053e-2
GO:0072050	S-shaped body morphogenesis	2.340102e-2
GO:0072049	comma-shaped body morphogenesis	2.340102e-2
GO:0007173	epidermal growth factor receptor signaling pathway	2.414305e-2
GO:0009154	purine ribonucleotide catabolic process	2.431799e-2
GO:0051261	protein depolymerization	2.468963e-2
GO:0045351	type I interferon biosynthetic process	2.468963e-2
GO:0007264	small GTPase mediated signal transduction	2.497151e-2
GO:0097084	vascular smooth muscle cell development	2.497932e-2
GO:0009166	nucleotide catabolic process	2.506153e-2
GO:0015862	uridine transport	2.513030e-2
GO:0070842	aggresome assembly	2.513030e-2
GO:0006493	protein O-linked glycosylation	2.526279e-2
GO:0060014	granulosa cell differentiation	2.538592e-2
GO:0042396	phosphagen biosynthetic process	2.538592e-2
GO:0000724	double-strand break repair via homologous recombination	2.548620e-2
GO:0010155	regulation of proton transport	2.598377e-2
GO:0006098	pentose-phosphate shunt	2.604321e-2
GO:0046849	bone remodeling	2.695991e-2
GO:0050779	RNA destabilization	2.712856e-2
GO:0019322	pentose biosynthetic process	2.712856e-2
GO:0072282	metanephric nephron tubule morphogenesis	2.716129e-2
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	2.758679e-2
GO:0046881	positive regulation of follicle-stimulating hormone secretion	2.764375e-2
GO:2000737	negative regulation of stem cell differentiation	2.764375e-2
GO:0045925	positive regulation of female receptivity	2.764375e-2
GO:0002678	positive regulation of chronic inflammatory response	2.805373e-2
GO:0045618	positive regulation of keratinocyte differentiation	2.814446e-2
GO:0032855	positive regulation of Rac GTPase activity	2.830370e-2
GO:2000209	regulation of anoikis	2.848506e-2
GO:0042487	regulation of odontogenesis of dentine-containing tooth	2.862167e-2
GO:0006927	transformed cell apoptosis	2.862167e-2
GO:0006290	pyrimidine dimer repair	2.862167e-2
GO:0003218	cardiac left ventricle formation	2.862167e-2
GO:0051156	glucose 6-phosphate metabolic process	2.863895e-2
GO:0015864	pyrimidine nucleoside transport	2.863895e-2