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CL:0000826

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Name:pro-B cell
Namespace:efo
Definition:"A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs." [GOC:add, ISBN:0781735149, PMID:12633665]
Xrefs:
links:
BTO:0003104
Synonyms: "pre-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048]
"pre-pro B cell" BROAD [PMID:17582343]
"pro-B lymphocyte" EXACT []
"pro-B-cell" EXACT []
"pro-B-lymphocyte" EXACT []
"progenitor B cell" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000838(lymphoid lineage restricted progenitor cell)
develops_from:CL:0000051(common lymphoid progenitor)



Children


disjoint from:CL:0000817 (precursor B cell)
develops from:CL:0000236 (B cell),CL:0000945 (lymphocyte of B lineage),CL:0000955 (pre-B-II cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.



Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000826 (pro-B cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
6.92e-147FFCP PHASE2:Hg19::chr11:111224819..111224845,+#_d06da43391ca56adb936d93ceac8db1ep2@CU689419
6.92e-147FFCP PHASE1:Hg19::chr11:111224819..111224845,+#_d06da43391ca56adb936d93ceac8db1ep2@CU689419
6.67e-144FFCP PHASE1:Hg19::chr5:132439186..132439209,+#_5bb408a7862a6984d509e7dd9c70b6afp13@HSPA4
6.67e-144FFCP PHASE2:Hg19::chr5:132439186..132439209,+#_5bb408a7862a6984d509e7dd9c70b6afp13@HSPA4
3.04e-141FFCP PHASE2:Hg19::chr3:121797478..121797512,-#_04e69eeb4599841ddea105996672c686p@chr3:121797478..121797512, -
3.04e-141FFCP PHASE1:Hg19::chr3:121797478..121797512,-#_04e69eeb4599841ddea105996672c686p@chr3:121797478..121797512, -
1.84e-138FFCP PHASE1:Hg19::chr19:7766976..7766982,-#_e3a2af9c3cbe6a5a052f9cf368af5f2ap9@FCER2
1.84e-138FFCP PHASE2:Hg19::chr19:7766976..7766982,-#_e3a2af9c3cbe6a5a052f9cf368af5f2ap9@FCER2
1.52e-135FFCP PHASE2:Hg19::chr9:37037005..37037011,+#_37ee5e7460a3c16c1ba96e3ea381f265p@chr9:37037005..37037011, +
1.52e-135FFCP PHASE1:Hg19::chr9:37037005..37037011,+#_37ee5e7460a3c16c1ba96e3ea381f265p@chr9:37037005..37037011, +
3.9e-131FFCP PHASE2:Hg19::chr12:111106975..111106991,-#_9dfc9363bdc468570a390c2b0643dadfp@chr12:111106975..111106991, -
3.9e-131FFCP PHASE1:Hg19::chr12:111106975..111106991,-#_9dfc9363bdc468570a390c2b0643dadfp@chr12:111106975..111106991, -
3.51e-130FFCP PHASE2:Hg19::chr1:31225180..31225207,-#_6c6fa8ec10e94da6a5feeaeb0ccc1c10p@chr1:31225180..31225207, -
3.51e-130FFCP PHASE1:Hg19::chr1:31225180..31225207,-#_6c6fa8ec10e94da6a5feeaeb0ccc1c10p@chr1:31225180..31225207, -
5.16e-123FFCP PHASE1:Hg19::chr11:111228348..111228370,-#_7aedab77fbde0fe92b9d3f0b057f7f4cp@chr11:111228348..111228370, -
5.16e-123FFCP PHASE2:Hg19::chr11:111228348..111228370,-#_7aedab77fbde0fe92b9d3f0b057f7f4cp@chr11:111228348..111228370, -
9.65e-122FFCP PHASE2:Hg19::chr3:112178705..112178716,-#_33f8323775a6eb18e7d9055334d92f54p@chr3:112178705..112178716, -
9.65e-122FFCP PHASE1:Hg19::chr3:112178705..112178716,-#_33f8323775a6eb18e7d9055334d92f54p@chr3:112178705..112178716, -
5.62e-121FFCP PHASE1:Hg19::chr14:106329470..106329481,-#_722eb5e851529df7b5b765a78922cf85p1@IGHJ6
5.62e-121FFCP PHASE2:Hg19::chr14:106329470..106329481,-#_722eb5e851529df7b5b765a78922cf85p1@IGHJ6
1.12e-120FFCP PHASE1:Hg19::chr8:110535068..110535088,+#_b87f7c58a0c21c03e5fb371dda82e76ep3@PKHD1L1
1.12e-120FFCP PHASE2:Hg19::chr8:110535068..110535088,+#_b87f7c58a0c21c03e5fb371dda82e76ep3@PKHD1L1
4.51e-120FFCP PHASE2:Hg19::chr18:56631315..56631351,+#_149b9e4e2c8056e2888d6773c70dd20ap@chr18:56631315..56631351, +
4.51e-120FFCP PHASE1:Hg19::chr18:56631315..56631351,+#_149b9e4e2c8056e2888d6773c70dd20ap@chr18:56631315..56631351, +
5.49e-120FFCP PHASE1:Hg19::chr9:37284234..37284268,+#_121510dfd8a593f4d660e7acfc0fc4e6p3@ZCCHC7
5.49e-120FFCP PHASE2:Hg19::chr9:37284234..37284268,+#_121510dfd8a593f4d660e7acfc0fc4e6p3@ZCCHC7
2.35e-119FFCP PHASE2:Hg19::chr6:6587579..6587601,-#_f78b3c91e749c8daccc3a3b72ba87d08p3@LY86-AS1
2.35e-119FFCP PHASE1:Hg19::chr6:6587579..6587601,-#_f78b3c91e749c8daccc3a3b72ba87d08p3@LY86-AS1
7.68e-117FFCP PHASE1:Hg19::chr22:22398325..22398339,-#_6d89dac1752526579b04092d53722863p1@PRAMEL
7.68e-117FFCP PHASE2:Hg19::chr22:22398325..22398339,-#_6d89dac1752526579b04092d53722863p1@PRAMEL
1.23e-115FFCP PHASE2:Hg19::chr17:9955844..9955857,-#_ec6890792495791fd9e463732fc9d9c1p@chr17:9955844..9955857, -
1.23e-115FFCP PHASE1:Hg19::chr17:9955844..9955857,-#_ec6890792495791fd9e463732fc9d9c1p@chr17:9955844..9955857, -
1.66e-115FFCP PHASE2:Hg19::chr2:232536651..232536664,+#_53fabc6774721ee92d5c728186f4f496p@chr2:232536651..232536664, +
1.66e-115FFCP PHASE1:Hg19::chr2:232536651..232536664,+#_53fabc6774721ee92d5c728186f4f496p@chr2:232536651..232536664, +
5.28e-115FFCP PHASE1:Hg19::chr16:85936539..85936562,+#_13a6ec94aed736ef5d428af645461741p3@IRF8
5.28e-115FFCP PHASE2:Hg19::chr16:85936539..85936562,+#_13a6ec94aed736ef5d428af645461741p3@IRF8
7.49e-115FFCP PHASE1:Hg19::chr22:50318813..50318835,+#_2bec7212f8226d3b80cfca7efbee45a8p@chr22:50318813..50318835, +
7.49e-115FFCP PHASE2:Hg19::chr22:50318813..50318835,+#_2bec7212f8226d3b80cfca7efbee45a8p@chr22:50318813..50318835, +
1.85e-114FFCP PHASE1:Hg19::chr2:65159562..65159594,-#_08a4611cab06792518f3215588c0c2e8p1@LOC400958
1.85e-114FFCP PHASE2:Hg19::chr2:65159562..65159594,-#_08a4611cab06792518f3215588c0c2e8p1@LOC400958
2.05e-114FFCP PHASE1:Hg19::chr16:12059021..12059048,+#_e21ed523f90c21065a8eb8f3199b8902p2@TNFRSF17
2.05e-114FFCP PHASE2:Hg19::chr16:12059021..12059048,+#_e21ed523f90c21065a8eb8f3199b8902p2@TNFRSF17
3.02e-114FFCP PHASE2:Hg19::chr16:12058994..12059003,+#_89707f817c561d0e96bb2991de2b8279p4@TNFRSF17
3.02e-114FFCP PHASE1:Hg19::chr16:12058994..12059003,+#_89707f817c561d0e96bb2991de2b8279p4@TNFRSF17
4.49e-114FFCP PHASE1:Hg19::chr11:60233507..60233518,+#_1dd652d8a8f5cb95ecabc938e3f96e78p3@MS4A1
4.49e-114FFCP PHASE2:Hg19::chr11:60233507..60233518,+#_1dd652d8a8f5cb95ecabc938e3f96e78p3@MS4A1
2.12e-112FFCP PHASE2:Hg19::chr10:98460644..98460661,-#_f727d13442f8cfac881b3d7714822528p5@PIK3AP1
2.12e-112FFCP PHASE1:Hg19::chr10:98460644..98460661,-#_f727d13442f8cfac881b3d7714822528p5@PIK3AP1
2.96e-112FFCP PHASE1:Hg19::chr15:31523055..31523071,-#_c1271927bc99a25acf5fe04c12fc7bc9p1@LOC283710
2.96e-112FFCP PHASE2:Hg19::chr15:31523055..31523071,-#_c1271927bc99a25acf5fe04c12fc7bc9p1@LOC283710
9.89e-112FFCP PHASE2:Hg19::chr14:106328158..106328168,-#_2a1f4de17731afa3bc96b632c09d62b9p6@IGHM
9.89e-112FFCP PHASE1:Hg19::chr14:106328158..106328168,-#_2a1f4de17731afa3bc96b632c09d62b9p6@IGHM
8.67e-110FFCP PHASE2:Hg19::chr1:111670644..111670656,-#_d14c7e2212be006fcd77338e8de82a6fp7@DRAM2
8.67e-110FFCP PHASE1:Hg19::chr1:111670644..111670656,-#_d14c7e2212be006fcd77338e8de82a6fp7@DRAM2
2.9e-109FFCP PHASE1:Hg19::chr11:14346810..14346831,-#_071683d8e5f7b256d9f27b63e1b0b602p@chr11:14346810..14346831, -
2.9e-109FFCP PHASE2:Hg19::chr11:14346810..14346831,-#_071683d8e5f7b256d9f27b63e1b0b602p@chr11:14346810..14346831, -
4.14e-109FFCP PHASE1:Hg19::chr9:37027587..37027596,-#_30f2fbb29b002b5bcc626735e3c688dfp@chr9:37027587..37027596, -
4.14e-109FFCP PHASE2:Hg19::chr8:11350850..11350859,+#_30f2fbb29b002b5bcc626735e3c688dfp@chr8:11350850..11350859, +
4.14e-109FFCP PHASE2:Hg19::chr9:37027587..37027596,-#_30f2fbb29b002b5bcc626735e3c688dfp@chr9:37027587..37027596, -
4.14e-109FFCP PHASE2:Hg19::chr11:111225012..111225024,-#_30f2fbb29b002b5bcc626735e3c688dfp@chr11:111225012..111225024, -
4.14e-109FFCP PHASE1:Hg19::chr11:111225012..111225024,-#_30f2fbb29b002b5bcc626735e3c688dfp@chr11:111225012..111225024, -
4.14e-109FFCP PHASE1:Hg19::chr8:11350850..11350859,+#_30f2fbb29b002b5bcc626735e3c688dfp@chr8:11350850..11350859, +
5.57e-109FFCP PHASE2:Hg19::chr2:232536534..232536561,-#_5265f2302cf8e4099e92788acdf7a16ep@chr2:232536534..232536561, -
5.57e-109FFCP PHASE1:Hg19::chr2:232536534..232536561,-#_5265f2302cf8e4099e92788acdf7a16ep@chr2:232536534..232536561, -
6.72e-109FFCP PHASE1:Hg19::chr14:106321725..106321735,-#_0b243cf3258892195fe5ea8423ee5a6bp7@FJ197674
6.72e-109FFCP PHASE2:Hg19::chr14:106321725..106321735,-#_0b243cf3258892195fe5ea8423ee5a6bp7@FJ197674
2.91e-108FFCP PHASE1:Hg19::chr14:106328131..106328143,-#_a3f86db2f3f6cb2eae9d3ea782b6f9c2p4@IGHM
2.91e-108FFCP PHASE2:Hg19::chr14:106328131..106328143,-#_a3f86db2f3f6cb2eae9d3ea782b6f9c2p4@IGHM
4.43e-108FFCP PHASE1:Hg19::chr19:18209729..18209742,-#_96dd8edc1ca87cbef25d70e544812c1cp3@IL12RB1
4.43e-108FFCP PHASE2:Hg19::chr19:18209729..18209742,-#_96dd8edc1ca87cbef25d70e544812c1cp3@IL12RB1
6.46e-108FFCP PHASE1:Hg19::chr13:31019875..31019895,+#_bfcb34db62ac0b2bc12cce4758d13adbp@chr13:31019875..31019895, +
6.46e-108FFCP PHASE2:Hg19::chr13:31019875..31019895,+#_bfcb34db62ac0b2bc12cce4758d13adbp@chr13:31019875..31019895, +
3.54e-107FFCP PHASE2:Hg19::chr12:111107001..111107019,-#_21423403e2ea2c74cc098323f2bd1885p@chr12:111107001..111107019, -
3.54e-107FFCP PHASE1:Hg19::chr12:111107001..111107019,-#_21423403e2ea2c74cc098323f2bd1885p@chr12:111107001..111107019, -
2.64e-106FFCP PHASE2:Hg19::chr2:17934493..17934510,+#_28457528318ac1669ac550c6d0e6124ap@chr2:17934493..17934510, +
2.64e-106FFCP PHASE1:Hg19::chr2:17934493..17934510,+#_28457528318ac1669ac550c6d0e6124ap@chr2:17934493..17934510, +
8.6e-106FFCP PHASE2:Hg19::chr19:7764975..7764994,-#_e67dea2d4dd5a61fadd215830df7ed62p7@FCER2
8.6e-106FFCP PHASE1:Hg19::chr19:7764975..7764994,-#_e67dea2d4dd5a61fadd215830df7ed62p7@FCER2
2.32e-105FFCP PHASE1:Hg19::chr19:42385139..42385152,+#_e6f34e1dd372d40375ac14fb1496d567p@chr19:42385139..42385152, +
2.32e-105FFCP PHASE2:Hg19::chr19:42385139..42385152,+#_e6f34e1dd372d40375ac14fb1496d567p@chr19:42385139..42385152, +
3.56e-105FFCP PHASE2:Hg19::chr22:42322346..42322363,-#_6910b6e077beb960610948ed7328002cp@chr22:42322346..42322363, -
3.56e-105FFCP PHASE1:Hg19::chr22:42322346..42322363,-#_6910b6e077beb960610948ed7328002cp@chr22:42322346..42322363, -
4.83e-105FFCP PHASE1:Hg19::chr11:111224975..111224995,-#_46225bb3ba3a779cc2943ae002c2ad2fp@chr11:111224975..111224995, -
4.83e-105FFCP PHASE2:Hg19::chr11:111224975..111224995,-#_46225bb3ba3a779cc2943ae002c2ad2fp@chr11:111224975..111224995, -
7.41e-105FFCP PHASE1:Hg19::chr11:111225158..111225201,+#_d8060d5ad7398147e7a79c1b6bff3ca4p1@CU689419
7.41e-105FFCP PHASE2:Hg19::chr11:111225158..111225201,+#_d8060d5ad7398147e7a79c1b6bff3ca4p1@CU689419
1.77e-104FFCP PHASE2:Hg19::chr11:111225132..111225169,-#_043ecd3a342e539c9861d401ce00bb39p@chr11:111225132..111225169, -
1.77e-104FFCP PHASE1:Hg19::chr11:111225132..111225169,-#_043ecd3a342e539c9861d401ce00bb39p@chr11:111225132..111225169, -
6.11e-104FFCP PHASE1:Hg19::chr9:95491611..95491638,-#_1daa1d557ef41cf54b8a60401c9566a1p@chr9:95491611..95491638, -
6.11e-104FFCP PHASE2:Hg19::chr9:95491611..95491638,-#_1daa1d557ef41cf54b8a60401c9566a1p@chr9:95491611..95491638, -
5.34e-103FFCP PHASE2:Hg19::chr8:110535027..110535055,+#_826cf9ecbb110827960a8b96f965af4cp2@PKHD1L1
5.34e-103FFCP PHASE1:Hg19::chr8:110535027..110535055,+#_826cf9ecbb110827960a8b96f965af4cp2@PKHD1L1
7.65e-103FFCP PHASE1:Hg19::chr14:106321710..106321722,-#_bfbe39fabe75e0532a0d94195df42426p3@FJ197674
7.65e-103FFCP PHASE2:Hg19::chr14:106321710..106321722,-#_bfbe39fabe75e0532a0d94195df42426p3@FJ197674
6.14e-102FFCP PHASE1:Hg19::chr19:35837510..35837514,+#_da5034cb558a9b4584a6f29842c63db0p@chr19:35837510..35837514, +
6.14e-102FFCP PHASE2:Hg19::chr19:35837510..35837514,+#_da5034cb558a9b4584a6f29842c63db0p@chr19:35837510..35837514, +
1.06e-101FFCP PHASE2:Hg19::chr11:111225198..111225226,-#_f0eac9f91487ae39172359b4a126a5a2p@chr11:111225198..111225226, -
1.06e-101FFCP PHASE1:Hg19::chr11:111225198..111225226,-#_f0eac9f91487ae39172359b4a126a5a2p@chr11:111225198..111225226, -
1.28e-101FFCP PHASE2:Hg19::chr14:106322154..106322163,-#_d284cac67b8071a2661a06199a299616p3@AJ294734
1.28e-101FFCP PHASE1:Hg19::chr14:106322154..106322163,-#_d284cac67b8071a2661a06199a299616p3@AJ294734

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