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MCL coexpression mm9:1233

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:128328919..128328934,-p2@Gdf11
Mm9::chr8:113245322..113245344,+p2@Mtss1l
Mm9::chr8:113245351..113245356,+p5@Mtss1l
Mm9::chr8:113245362..113245386,+p1@Mtss1l
Mm9::chr8:113245555..113245624,+p3@Mtss1l
Mm9::chr8:113265086..113265105,+p@chr8:113265086..113265105
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0031016pancreas development0.0179696488248507
GO:0048593camera-type eye morphogenesis0.0179696488248507
GO:0001657ureteric bud development0.0179696488248507
GO:0048592eye morphogenesis0.0179696488248507
GO:0001656metanephros development0.0179696488248507
GO:0001822kidney development0.0179696488248507
GO:0048469cell maturation0.0179696488248507
GO:0043010camera-type eye development0.0179696488248507
GO:0001655urogenital system development0.0179696488248507
GO:0045596negative regulation of cell differentiation0.0179696488248507
GO:0021700developmental maturation0.0179696488248507
GO:0001654eye development0.0179696488248507
GO:0051093negative regulation of developmental process0.0179696488248507
GO:0008285negative regulation of cell proliferation0.0189323085833249
GO:0008083growth factor activity0.0214793458609544
GO:0045595regulation of cell differentiation0.0214793458609544
GO:0007423sensory organ development0.0245761373633988
GO:0005125cytokine activity0.0267048947813754
GO:0050793regulation of developmental process0.0302646717050117
GO:0042127regulation of cell proliferation0.0356023667342355
GO:0008283cell proliferation0.0494165342683395



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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