MCL coexpression mm9:1603

Phase1 CAGE Peaks

	Short description
Mm9::chr11:96214469..96214478,+	p@chr11:96214469..96214478 +
Mm9::chr1:23278645..23278655,+	p2@Mir30a
Mm9::chr2:170322641..170322647,-	p1@Cyp24a1
Mm9::chr6:38074449..38074456,-	p18@Atp6v0a4
Mm9::chr9:48547080..48547100,-	p@chr9:48547080..48547100 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008403	25-hydroxycholecalciferol-24-hydroxylase activity	0.0195584287514381
GO:0042359	vitamin D metabolic process	0.0260679047098323
GO:0033176	proton-transporting V-type ATPase complex	0.0260679047098323
GO:0016471	vacuolar proton-transporting V-type ATPase complex	0.0260679047098323
GO:0015991	ATP hydrolysis coupled proton transport	0.0260679047098323
GO:0015988	energy coupled proton transport, against electrochemical gradient	0.0260679047098323
GO:0005774	vacuolar membrane	0.042619183367311
GO:0044437	vacuolar part	0.042619183367311
GO:0005903	brush border	0.042619183367311
GO:0006775	fat-soluble vitamin metabolic process	0.042619183367311
GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism	0.042619183367311

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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