MCL coexpression mm9:318

Phase1 CAGE Peaks

	Short description
Mm9::chr10:12912536..12912606,-	p@chr10:12912536..12912606 -
Mm9::chr10:62486081..62486100,+	p@chr10:62486081..62486100 +
Mm9::chr11:69223942..69223955,-	p@chr11:69223942..69223955 -
Mm9::chr11:69224857..69224885,+	p@chr11:69224857..69224885 +
Mm9::chr11:98064472..98064487,-	p@chr11:98064472..98064487 -
Mm9::chr11:98820837..98820841,-	p@chr11:98820837..98820841 -
Mm9::chr12:56590796..56590811,-	p@chr12:56590796..56590811 -
Mm9::chr15:101077003..101077018,+	p@chr15:101077003..101077018 +
Mm9::chr16:55822241..55822258,-	p1@Nfkbiz
Mm9::chr16:94792724..94792748,-	p@chr16:94792724..94792748 -
Mm9::chr18:35091545..35091574,-	p2@Etf1
Mm9::chr19:46378880..46378896,+	p8@Nfkb2
Mm9::chr19:46379032..46379054,-	p@chr19:46379032..46379054 -
Mm9::chr1:182781262..182781303,+	p1@BC031781
Mm9::chr3:65762096..65762111,-	p1@Ccnl1
Mm9::chr4:33335475..33335493,-	p1@Pnrc1
Mm9::chr5:22938641..22938646,+	p@chr5:22938641..22938646 +
Mm9::chr6:56664952..56664965,+	p4@Avl9
Mm9::chr8:72240726..72240742,-	p3@Zfp869
Mm9::chr8:87186740..87186758,-	p1@Ier2
Mm9::chr8:87502000..87502015,-	p@chr8:87502000..87502015 -
Mm9::chr8:87502350..87502362,-	p2@Junb
Mm9::chr8:87502423..87502439,-	p4@Junb
Mm9::chr8:87502608..87502623,-	p1@Junb
Mm9::chrX:48371786..48371860,-	p@chrX:48371786..48371860 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0002266	follicular dendritic cell activation	0.018015548174587
GO:0002268	follicular dendritic cell differentiation	0.018015548174587
GO:0016149	translation release factor activity, codon specific	0.018015548174587
GO:0010467	gene expression	0.018015548174587
GO:0008023	transcription elongation factor complex	0.018015548174587
GO:0008079	translation termination factor activity	0.018015548174587
GO:0006415	translational termination	0.018015548174587
GO:0003747	translation release factor activity	0.018015548174587
GO:0006355	regulation of transcription, DNA-dependent	0.0187493882502284
GO:0003700	transcription factor activity	0.0187493882502284
GO:0002467	germinal center formation	0.0187493882502284
GO:0006351	transcription, DNA-dependent	0.0187493882502284
GO:0032774	RNA biosynthetic process	0.0187493882502284
GO:0045449	regulation of transcription	0.0187493882502284
GO:0048536	spleen development	0.0187493882502284
GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0187493882502284
GO:0006350	transcription	0.0187493882502284
GO:0010468	regulation of gene expression	0.0200238177225507
GO:0031323	regulation of cellular metabolic process	0.0215902506335981
GO:0043624	cellular protein complex disassembly	0.0215902506335981
GO:0043241	protein complex disassembly	0.0217480607147832
GO:0019222	regulation of metabolic process	0.0217480607147832
GO:0032984	macromolecular complex disassembly	0.0218959546766158
GO:0016070	RNA metabolic process	0.0219455121922195
GO:0048535	lymph node development	0.0244488528490187
GO:0051726	regulation of cell cycle	0.0261174403194484
GO:0022411	cellular component disassembly	0.0292719506150735
GO:0003676	nucleic acid binding	0.0394693602620986
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0498253690261291

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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