MCL coexpression mm9:770

Phase1 CAGE Peaks

	Short description
Mm9::chr10:79317403..79317419,+	p1@Ptbp1
Mm9::chr11:116714397..116714413,-	p1@Srsf2
Mm9::chr14:52723666..52723686,-	p1@Hnrnpc
Mm9::chr14:52723690..52723701,-	p2@Hnrnpc
Mm9::chr17:80606639..80606648,-	p1@Srsf7
Mm9::chr5:114580714..114580735,-	p@chr5:114580714..114580735 -
Mm9::chr6:49214013..49214059,-	p1@Tra2a
Mm9::chr9:62189896..62189919,+	p5@Anp32a
Mm9::chrX:50265409..50265538,+	p1@Phf6

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008380	RNA splicing	0.000469208992587783
GO:0006397	mRNA processing	0.000469561809974684
GO:0016071	mRNA metabolic process	0.000469561809974684
GO:0006396	RNA processing	0.000893852557727055
GO:0003723	RNA binding	0.00257348900595761
GO:0005634	nucleus	0.0041718075817128
GO:0016070	RNA metabolic process	0.00756204945523937
GO:0010467	gene expression	0.0132872715897345
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0172880752005752
GO:0045120	pronucleus	0.0189441460441609
GO:0016363	nuclear matrix	0.0189441460441609
GO:0043231	intracellular membrane-bound organelle	0.0189441460441609
GO:0043227	membrane-bound organelle	0.0189441460441609
GO:0030529	ribonucleoprotein complex	0.0215939053400419
GO:0043229	intracellular organelle	0.0273558350317909
GO:0043226	organelle	0.0273558350317909
GO:0000166	nucleotide binding	0.0273558350317909
GO:0043283	biopolymer metabolic process	0.0300128468366282

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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