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MCL coexpression mm9:2701

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:68673507..68673519,-p9@Ndel1
Mm9::chr11:68673524..68673565,-p5@Ndel1
Mm9::chr18:61696224..61696237,-p4@Arhgef37


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008090retrograde axon cargo transport0.00704385189127424
GO:0047496vesicle transport along microtubule0.00704385189127424
GO:0001833inner cell mass cell proliferation0.00704385189127424
GO:0060052neurofilament cytoskeleton organization and biogenesis0.00704385189127424
GO:0060053neurofilament cytoskeleton0.00704385189127424
GO:0021955central nervous system neuron axonogenesis0.00704385189127424
GO:0008088axon cargo transport0.00704385189127424
GO:0001832blastocyst growth0.00801238152632444
GO:0045104intermediate filament cytoskeleton organization and biogenesis0.00931353750068482
GO:0045103intermediate filament-based process0.00941314752743011
GO:0021954central nervous system neuron development0.00941314752743011
GO:0021953central nervous system neuron differentiation0.00986139264778393
GO:0001824blastocyst development0.0117578143108193
GO:0005813centrosome0.0142730683060031
GO:0008017microtubule binding0.0142730683060031
GO:0048589developmental growth0.0142730683060031
GO:0005815microtubule organizing center0.0142730683060031
GO:0015631tubulin binding0.0142730683060031
GO:0001764neuron migration0.0142730683060031
GO:0030424axon0.0150268840347184
GO:0000226microtubule cytoskeleton organization and biogenesis0.0150268840347184
GO:0007018microtubule-based movement0.0186021724946833
GO:0030705cytoskeleton-dependent intracellular transport0.0209554593765408
GO:0005875microtubule associated complex0.0209554593765408
GO:0043005neuron projection0.0220968242663307
GO:0001701in utero embryonic development0.0220968242663307
GO:0045111intermediate filament cytoskeleton0.0220968242663307
GO:0007409axonogenesis0.0267901166931463
GO:0048667neuron morphogenesis during differentiation0.0267901166931463
GO:0048812neurite morphogenesis0.0267901166931463
GO:0007017microtubule-based process0.0279936307420963
GO:0000904cellular morphogenesis during differentiation0.0282789936223216
GO:0005874microtubule0.0282789936223216
GO:0031175neurite development0.0282789936223216
GO:0048666neuron development0.0298507020689676
GO:0043009chordate embryonic development0.0298507020689676
GO:0009792embryonic development ending in birth or egg hatching0.0298507020689676
GO:0007417central nervous system development0.0299734434426064
GO:0032990cell part morphogenesis0.0317628577143738
GO:0030030cell projection organization and biogenesis0.0317628577143738
GO:0048858cell projection morphogenesis0.0317628577143738
GO:0016477cell migration0.0317628577143738
GO:0030182neuron differentiation0.0317628577143738
GO:0015630microtubule cytoskeleton0.0320495261052978
GO:0048699generation of neurons0.0339903321051276
GO:0051674localization of cell0.0339903321051276
GO:0006928cell motility0.0339903321051276
GO:0008092cytoskeletal protein binding0.0340117419892956
GO:0022008neurogenesis0.0340117419892956
GO:0042995cell projection0.0358954692379335
GO:0009790embryonic development0.0414178491206925
GO:0007010cytoskeleton organization and biogenesis0.0414178491206925
GO:0000902cell morphogenesis0.0414178491206925
GO:0032989cellular structure morphogenesis0.0414178491206925
GO:0008283cell proliferation0.0414178491206925
GO:0044430cytoskeletal part0.0457850372932825
GO:0046907intracellular transport0.049133956350362



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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