MCL coexpression mm9:378

Phase1 CAGE Peaks

	Short description
Mm9::chr10:25018083..25018119,-	p@chr10:25018083..25018119 -
Mm9::chr10:25156813..25156838,+	p@chr10:25156813..25156838 +
Mm9::chr11:78008044..78008065,+	p3@Proca1
Mm9::chr11:83986974..83986996,+	p5@Acaca
Mm9::chr13:37575274..37575296,+	p@chr13:37575274..37575296 +
Mm9::chr15:84015494..84015535,-	p@chr15:84015494..84015535 -
Mm9::chr17:10689280..10689294,+	p3@ENSMUST00000161274
Mm9::chr17:10689300..10689307,+	p4@ENSMUST00000161274
Mm9::chr19:3972322..3972345,+	p4@Aldh3b2
Mm9::chr19:8915055..8915067,+	p9@Bscl2
Mm9::chr2:150426133..150426149,-	p4@2310001A20Rik
Mm9::chr2:150426151..150426199,-	p2@2310001A20Rik
Mm9::chr2:26465321..26465332,+	p@chr2:26465321..26465332 +
Mm9::chr3:97503099..97503129,-	p@chr3:97503099..97503129 -
Mm9::chr6:115312361..115312378,+	p@chr6:115312361..115312378 +
Mm9::chr8:127387001..127387014,+	p3@Gnpat
Mm9::chr8:127387091..127387127,+	p2@Gnpat
Mm9::chr8:18606895..18606902,+	p@chr8:18606895..18606902 +
Mm9::chr9:65248675..65248686,+	p@chr9:65248675..65248686 +
Mm9::chr9:65248704..65248719,+	p@chr9:65248704..65248719 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008611	ether lipid biosynthetic process	0.00449241220621267
GO:0016843	amine-lyase activity	0.00449241220621267
GO:0016844	strictosidine synthase activity	0.00449241220621267
GO:0016287	glycerone-phosphate O-acyltransferase activity	0.00449241220621267
GO:0046485	ether lipid metabolic process	0.00449241220621267
GO:0004075	biotin carboxylase activity	0.00842142699329734
GO:0005782	peroxisomal matrix	0.00842142699329734
GO:0003989	acetyl-CoA carboxylase activity	0.00842142699329734
GO:0009374	biotin binding	0.00898187114488589
GO:0016413	O-acetyltransferase activity	0.00898187114488589
GO:0008610	lipid biosynthetic process	0.0105996946032502
GO:0016421	CoA carboxylase activity	0.0105996946032502
GO:0016840	carbon-nitrogen lyase activity	0.0105996946032502
GO:0016885	ligase activity, forming carbon-carbon bonds	0.0105996946032502
GO:0046504	glycerol ether biosynthetic process	0.0105996946032502
GO:0045017	glycerolipid biosynthetic process	0.0105996946032502
GO:0009058	biosynthetic process	0.0105996946032502
GO:0031903	microbody membrane	0.0200624266775967
GO:0005778	peroxisomal membrane	0.0200624266775967
GO:0044439	peroxisomal part	0.0202827699919549
GO:0044438	microbody part	0.0202827699919549
GO:0046486	glycerolipid metabolic process	0.0247882917154048
GO:0006662	glycerol ether metabolic process	0.0247882917154048
GO:0044255	cellular lipid metabolic process	0.0247882917154048
GO:0008374	O-acyltransferase activity	0.0268689504028476
GO:0006629	lipid metabolic process	0.030024142586548
GO:0016407	acetyltransferase activity	0.0471297987841342

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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