MCL coexpression mm9:452
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr10:19311758..19311893,+ | p1@Ifngr1 |
| Mm9::chr15:76073831..76073878,- | p1@Parp10 |
| Mm9::chr17:34324273..34324290,- | p1@Psmb9 |
| Mm9::chr17:34324296..34324325,- | p2@Psmb9 |
| Mm9::chr17:34324734..34324773,+ | p1@Tap1 |
| Mm9::chr17:34335287..34335329,+ | p1@Psmb8 |
| Mm9::chr17:34335330..34335345,+ | p2@Psmb8 |
| Mm9::chr17:34341452..34341518,+ | p1@Tap2 |
| Mm9::chr19:46380069..46380117,- | p1@uc008hss.1 |
| Mm9::chr5:38871392..38871478,- | p1@Slc2a9 |
| Mm9::chr6:125181666..125181707,- | p2@Tapbpl |
| Mm9::chr6:54766777..54766813,+ | p3@Znrf2 |
| Mm9::chr7:4610585..4610628,- | p1@Ppp6r1 |
| Mm9::chr8:123260252..123260264,+ | p1@Irf8 |
| Mm9::chr8:91159958..91160015,- | p1@Snx20 |
| Mm9::chr9:95855239..95855262,+ | p2@Xrn1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0002376 | immune system process | 0.000126456316580598 |
| GO:0006955 | immune response | 0.000216050847144709 |
| GO:0019882 | antigen processing and presentation | 0.000216050847144709 |
| GO:0015198 | oligopeptide transporter activity | 0.000239109370773241 |
| GO:0015197 | peptide transporter activity | 0.000239109370773241 |
| GO:0006857 | oligopeptide transport | 0.000239109370773241 |
| GO:0005839 | proteasome core complex (sensu Eukaryota) | 0.00124764663859537 |
| GO:0004298 | threonine endopeptidase activity | 0.00133988942907512 |
| GO:0000502 | proteasome complex (sensu Eukaryota) | 0.00213944119925394 |
| GO:0015833 | peptide transport | 0.00357056488411637 |
| GO:0043231 | intracellular membrane-bound organelle | 0.0067041546691773 |
| GO:0043227 | membrane-bound organelle | 0.0067041546691773 |
| GO:0022804 | active transmembrane transporter activity | 0.00816039369193958 |
| GO:0004534 | 5'-3' exoribonuclease activity | 0.0143469667541324 |
| GO:0043229 | intracellular organelle | 0.0143469667541324 |
| GO:0043226 | organelle | 0.0143469667541324 |
| GO:0043492 | ATPase activity, coupled to movement of substances | 0.0143469667541324 |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | 0.0143469667541324 |
| GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.0143469667541324 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 0.0143469667541324 |
| GO:0019941 | modification-dependent protein catabolic process | 0.0143469667541324 |
| GO:0043632 | modification-dependent macromolecule catabolic process | 0.0143469667541324 |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | 0.0143469667541324 |
| GO:0044257 | cellular protein catabolic process | 0.0143469667541324 |
| GO:0015399 | primary active transmembrane transporter activity | 0.0143469667541324 |
| GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.0143469667541324 |
| GO:0019883 | antigen processing and presentation of endogenous antigen | 0.0143469667541324 |
| GO:0002483 | antigen processing and presentation of endogenous peptide antigen | 0.0143469667541324 |
| GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I | 0.0143469667541324 |
| GO:0044444 | cytoplasmic part | 0.0158273200625474 |
| GO:0016787 | hydrolase activity | 0.0162258501755409 |
| GO:0008409 | 5'-3' exonuclease activity | 0.0162484168177538 |
| GO:0030163 | protein catabolic process | 0.0225127277997454 |
| GO:0005783 | endoplasmic reticulum | 0.0281356080350887 |
| GO:0005355 | glucose transmembrane transporter activity | 0.0296747923763085 |
| GO:0015145 | monosaccharide transmembrane transporter activity | 0.0308702147567943 |
| GO:0015149 | hexose transmembrane transporter activity | 0.0308702147567943 |
| GO:0042623 | ATPase activity, coupled | 0.0310720046932331 |
| GO:0044265 | cellular macromolecule catabolic process | 0.0310720046932331 |
| GO:0043285 | biopolymer catabolic process | 0.0313768624398188 |
| GO:0007569 | cell aging | 0.0313768624398188 |
| GO:0016896 | exoribonuclease activity, producing 5'-phosphomonoesters | 0.0313768624398188 |
| GO:0004532 | exoribonuclease activity | 0.0313768624398188 |
| GO:0044424 | intracellular part | 0.0326666036173901 |
| GO:0005887 | integral to plasma membrane | 0.0335838026201669 |
| GO:0016887 | ATPase activity | 0.0335838026201669 |
| GO:0031226 | intrinsic to plasma membrane | 0.0335838026201669 |
| GO:0022857 | transmembrane transporter activity | 0.0335838026201669 |
| GO:0005622 | intracellular | 0.0335838026201669 |
| GO:0005737 | cytoplasm | 0.0335838026201669 |
| GO:0032200 | telomere organization and biogenesis | 0.0338962854418947 |
| GO:0000723 | telomere maintenance | 0.0338962854418947 |
| GO:0016796 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.0352043359394095 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 0.0364253721357344 |
| GO:0009057 | macromolecule catabolic process | 0.0364253721357344 |
| GO:0022892 | substrate-specific transporter activity | 0.0381679905325293 |
| GO:0005829 | cytosol | 0.0462239333408587 |
| GO:0015758 | glucose transport | 0.0474632960498069 |
| GO:0008645 | hexose transport | 0.0474632960498069 |
| GO:0015749 | monosaccharide transport | 0.0474632960498069 |
| GO:0007568 | aging | 0.0474632960498069 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| connective tissue cell | 3.58e-10 | 46 |
| mesenchymal cell | 3.58e-10 | 46 |
| motile cell | 4.29e-09 | 54 |
| hematopoietic cell | 8.39e-09 | 32 |
| hematopoietic oligopotent progenitor cell | 8.39e-09 | 32 |
| hematopoietic stem cell | 8.39e-09 | 32 |
| angioblastic mesenchymal cell | 8.39e-09 | 32 |
| hematopoietic multipotent progenitor cell | 8.39e-09 | 32 |
| hematopoietic lineage restricted progenitor cell | 5.25e-07 | 25 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
{{{tfbs_overrepresentation_jaspar}}} |
