MCL coexpression mm9:2239

Phase1 CAGE Peaks

	Short description
Mm9::chr18:43367364..43367375,+	p5@LOC100047004 p5@Stk32a
Mm9::chr4:88940766..88940807,+	p1@uc008toj.1
Mm9::chr7:148629213..148629258,-	p2@Lrdd
Mm9::chr7:52721841..52721857,-	p7@Bax

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030850	prostate gland development	0.0175308844484407
GO:0050680	negative regulation of epithelial cell proliferation	0.0262934451202766
GO:0007431	salivary gland development	0.0306689623514255
GO:0035272	exocrine system development	0.0306689623514255
GO:0050678	regulation of epithelial cell proliferation	0.0420487650152741
GO:0050673	epithelial cell proliferation	0.0452521387752267

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
autonomic neuron	2.20e-08	9
non-terminally differentiated cell	2.04e-07	49
migratory neural crest cell	4.28e-07	10
neuron associated cell	4.28e-07	10
glial cell (sensu Vertebrata)	4.28e-07	10
neuron associated cell (sensu Vertebrata)	4.28e-07	10
glial cell	4.28e-07	10
glioblast	4.28e-07	10
glioblast (sensu Vertebrata)	4.28e-07	10

Uber Anatomy

Ontology term	p-value	n
peripheral nervous system	4.61e-09	11
autonomic nervous system	2.20e-08	9

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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