MCL coexpression mm9:2112
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr14:56097590..56097604,+ | p3@Dhrs4 |
| Mm9::chr18:34569069..34569112,+ | p1@Pkd2l2 |
| Mm9::chr2:10001781..10001793,- | p3@Atp5c1 |
| Mm9::chr2:102913921..102913945,+ | p2@Apip |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0005753 | mitochondrial proton-transporting ATP synthase complex | 0.0335122051150373 |
| GO:0001758 | retinal dehydrogenase activity | 0.0335122051150373 |
| GO:0004090 | carbonyl reductase (NADPH) activity | 0.0335122051150373 |
| GO:0043288 | apocarotenoid metabolic process | 0.0335122051150373 |
| GO:0042574 | retinal metabolic process | 0.0335122051150373 |
| GO:0045261 | proton-transporting ATP synthase complex, catalytic core F(1) | 0.0335122051150373 |
| GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain | 0.0335122051150373 |
| GO:0016101 | diterpenoid metabolic process | 0.043528192063967 |
| GO:0001523 | retinoid metabolic process | 0.043528192063967 |
| GO:0006721 | terpenoid metabolic process | 0.043528192063967 |
| GO:0006776 | vitamin A metabolic process | 0.043528192063967 |
| GO:0045259 | proton-transporting ATP synthase complex | 0.043528192063967 |
| GO:0006775 | fat-soluble vitamin metabolic process | 0.043528192063967 |
| GO:0006720 | isoprenoid metabolic process | 0.043528192063967 |
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | 0.043528192063967 |
| GO:0015075 | ion transmembrane transporter activity | 0.043528192063967 |
| GO:0015985 | energy coupled proton transport, down electrochemical gradient | 0.043528192063967 |
| GO:0015986 | ATP synthesis coupled proton transport | 0.043528192063967 |
| GO:0006754 | ATP biosynthetic process | 0.043528192063967 |
| GO:0006753 | nucleoside phosphate metabolic process | 0.043528192063967 |
| GO:0046933 | hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.043528192063967 |
| GO:0016469 | proton-transporting two-sector ATPase complex | 0.043528192063967 |
| GO:0046961 | hydrogen ion transporting ATPase activity, rotational mechanism | 0.043528192063967 |
| GO:0006811 | ion transport | 0.043528192063967 |
| GO:0016903 | oxidoreductase activity, acting on the aldehyde or oxo group of donors | 0.043528192063967 |
| GO:0022891 | substrate-specific transmembrane transporter activity | 0.043528192063967 |
| GO:0046034 | ATP metabolic process | 0.043528192063967 |
| GO:0019748 | secondary metabolic process | 0.043528192063967 |
| GO:0044455 | mitochondrial membrane part | 0.043528192063967 |
| GO:0009145 | purine nucleoside triphosphate biosynthetic process | 0.043528192063967 |
| GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 0.043528192063967 |
| GO:0009201 | ribonucleoside triphosphate biosynthetic process | 0.043528192063967 |
| GO:0019829 | cation-transporting ATPase activity | 0.043528192063967 |
| GO:0009142 | nucleoside triphosphate biosynthetic process | 0.043528192063967 |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 0.043528192063967 |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 0.043528192063967 |
| GO:0006119 | oxidative phosphorylation | 0.043528192063967 |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 0.043528192063967 |
| GO:0015992 | proton transport | 0.043528192063967 |
| GO:0022857 | transmembrane transporter activity | 0.043528192063967 |
| GO:0006752 | group transfer coenzyme metabolic process | 0.043528192063967 |
| GO:0009141 | nucleoside triphosphate metabolic process | 0.043528192063967 |
| GO:0009152 | purine ribonucleotide biosynthetic process | 0.043528192063967 |
| GO:0006818 | hydrogen transport | 0.043528192063967 |
| GO:0009260 | ribonucleotide biosynthetic process | 0.043528192063967 |
| GO:0006766 | vitamin metabolic process | 0.043528192063967 |
| GO:0022892 | substrate-specific transporter activity | 0.043528192063967 |
| GO:0009150 | purine ribonucleotide metabolic process | 0.043528192063967 |
| GO:0006164 | purine nucleotide biosynthetic process | 0.043528192063967 |
| GO:0005739 | mitochondrion | 0.043528192063967 |
| GO:0009259 | ribonucleotide metabolic process | 0.0457595193689358 |
| GO:0006163 | purine nucleotide metabolic process | 0.0474284687075218 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| epithelial tube | 3.93e-07 | 47 |
| primary circulatory organ | 5.97e-07 | 18 |
| heart | 5.97e-07 | 18 |
| primitive heart tube | 5.97e-07 | 18 |
| primary heart field | 5.97e-07 | 18 |
| anterior lateral plate mesoderm | 5.97e-07 | 18 |
| heart tube | 5.97e-07 | 18 |
| heart primordium | 5.97e-07 | 18 |
| cardiac mesoderm | 5.97e-07 | 18 |
| cardiogenic plate | 5.97e-07 | 18 |
| heart rudiment | 5.97e-07 | 18 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.600426 |
| MA0004.1 | 0.6888 |
| MA0006.1 | 0.497533 |
| MA0007.1 | 0.672186 |
| MA0009.1 | 1.15569 |
| MA0014.1 | 0.276754 |
| MA0017.1 | 0.528196 |
| MA0019.1 | 0.964875 |
| MA0024.1 | 1.11019 |
| MA0025.1 | 1.39562 |
| MA0027.1 | 2.81824 |
| MA0028.1 | 0.509589 |
| MA0029.1 | 1.08753 |
| MA0030.1 | 1.09438 |
| MA0031.1 | 1.05719 |
| MA0038.1 | 0.846479 |
| MA0040.1 | 1.16866 |
| MA0041.1 | 0.604221 |
| MA0042.1 | 0.589368 |
| MA0043.1 | 1.25564 |
| MA0046.1 | 1.1929 |
| MA0048.1 | 1.35097 |
| MA0050.1 | 0.731539 |
| MA0051.1 | 0.856094 |
| MA0052.1 | 1.17701 |
| MA0055.1 | 0.396346 |
| MA0056.1 | 0 |
| MA0057.1 | 0.251896 |
| MA0058.1 | 0.581673 |
| MA0059.1 | 0.59559 |
| MA0060.1 | 0.403071 |
| MA0061.1 | 0.438628 |
| MA0063.1 | 0 |
| MA0066.1 | 0.834648 |
| MA0067.1 | 1.50873 |
| MA0068.1 | 0.256913 |
| MA0069.1 | 1.17737 |
| MA0070.1 | 1.16732 |
| MA0071.1 | 0.73062 |
| MA0072.1 | 1.15853 |
| MA0073.1 | 0.0140887 |
| MA0074.1 | 0.795862 |
| MA0076.1 | 0.550092 |
| MA0077.1 | 1.13603 |
| MA0078.1 | 0.891476 |
| MA0081.1 | 0.621611 |
| MA0083.1 | 1.25482 |
| MA0084.1 | 1.84013 |
| MA0087.1 | 1.21037 |
| MA0088.1 | 1.1032 |
| MA0089.1 | 0 |
| MA0090.1 | 0.650768 |
| MA0091.1 | 0.703314 |
| MA0092.1 | 0.651119 |
| MA0093.1 | 0.519148 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.783305 |
| MA0101.1 | 0.605676 |
| MA0103.1 | 0.540576 |
| MA0105.1 | 0.313353 |
| MA0106.1 | 0.899777 |
| MA0107.1 | 0.533522 |
| MA0108.2 | 0.989014 |
| MA0109.1 | 0 |
| MA0111.1 | 0.666525 |
| MA0113.1 | 0.869608 |
| MA0114.1 | 0.43587 |
| MA0115.1 | 1.25852 |
| MA0116.1 | 0.497293 |
| MA0117.1 | 1.22527 |
| MA0119.1 | 0.606338 |
| MA0122.1 | 1.24573 |
| MA0124.1 | 1.45461 |
| MA0125.1 | 1.37907 |
| MA0130.1 | 0 |
| MA0131.1 | 0.960068 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.29308 |
| MA0136.1 | 0.817395 |
| MA0139.1 | 0.365453 |
| MA0140.1 | 0.78318 |
| MA0141.1 | 0.563066 |
| MA0142.1 | 1.04199 |
| MA0143.1 | 0.887119 |
| MA0144.1 | 0.439506 |
| MA0145.1 | 1.14526 |
| MA0146.1 | 0.647546 |
| MA0147.1 | 0.453952 |
| MA0148.1 | 0.706718 |
| MA0149.1 | 0.611881 |
| MA0062.2 | 0.319836 |
| MA0035.2 | 0.788288 |
| MA0039.2 | 0.238019 |
| MA0138.2 | 0.951653 |
| MA0002.2 | 0.368961 |
| MA0137.2 | 0.559766 |
| MA0104.2 | 0.386166 |
| MA0047.2 | 0.845655 |
| MA0112.2 | 0.211985 |
| MA0065.2 | 0.212467 |
| MA0150.1 | 0.67206 |
| MA0151.1 | 0 |
| MA0152.1 | 0.84577 |
| MA0153.1 | 1.31015 |
| MA0154.1 | 0.263609 |
| MA0155.1 | 0.650923 |
| MA0156.1 | 0.549102 |
| MA0157.1 | 1.0083 |
| MA0158.1 | 0 |
| MA0159.1 | 0.465802 |
| MA0160.1 | 0.71003 |
| MA0161.1 | 0 |
| MA0162.1 | 0.346529 |
| MA0163.1 | 0.0996272 |
| MA0164.1 | 0.817786 |
| MA0080.2 | 0.534538 |
| MA0018.2 | 0.828253 |
| MA0099.2 | 0.944966 |
| MA0079.2 | 0.0553806 |
| MA0102.2 | 1.8929 |
| MA0258.1 | 0.419871 |
| MA0259.1 | 0.441366 |
| MA0442.1 | 0 |
