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CL:0002586

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Name:retinal pigment epithelial cell
Namespace:cell
Definition:"An epithelial cell of the retinal pigmented epithelium." [GOC:tfm]
Xrefs:
links:

BTO:0004910

FMA:75802
Created by:tmeehan
Creation date:2011-03-06T03:37:09Z


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000066(epithelial cell),CL:0000149(visual pigment cell),CL:0002371(somatic cell)
part_of:UBERON:0001782(pigmented layer of retina)



Children


derives from:FF:0000158 (human retinal pigment epithelial cell sample),FF:0300100 (ARPE-19 EMT induced with TGF-beta and TNF-alpha sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

  • 11215-116A9 (Retinal Pigment Epithelial Cells, donor0)
  • 11528-119I7 (Retinal Pigment Epithelial Cells, donor1)
  • 11608-120I6 (Retinal Pigment Epithelial Cells, donor2)
  • 11689-122I6 (Retinal Pigment Epithelial Cells, donor3)
  • 13663-147C9 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13664-147D1 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13665-147D2 (ARPE-19 EMT induced with TGF-beta and TNF-alpha, 06hr00min, biol_rep2)
  • 13666-147D3 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13667-147D4 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13668-147D5 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)

... further results Mouse (Mus musculus)

  • 11215-116A9 (Retinal Pigment Epithelial Cells, donor0)
  • 11528-119I7 (Retinal Pigment Epithelial Cells, donor1)
  • 11608-120I6 (Retinal Pigment Epithelial Cells, donor2)
  • 11689-122I6 (Retinal Pigment Epithelial Cells, donor3)
  • 13663-147C9 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13664-147D1 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13665-147D2 (ARPE-19 EMT induced with TGF-beta and TNF-alpha, 06hr00min, biol_rep2)
  • 13666-147D3 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13667-147D4 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)
  • 13668-147D5 (ARPE-19 EMT induced with TGF-beta and TNF-alpha)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002586 (retinal pigment epithelial cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
2.79e-195FFCP PHASE2:Hg19::chr1:147150847..147150854,-#_2a551d0e3647683b0c37cad2b3358d73p@chr1:147150847..147150854, -
2.79e-195FFCP PHASE1:Hg19::chr1:147150847..147150854,-#_2a551d0e3647683b0c37cad2b3358d73p@chr1:147150847..147150854, -
3.27e-147FFCP PHASE2:Hg19::chr13:51913806..51913817,+#_709b708b702ba970e9d6241c87f75c22p2@SERPINE3
3.27e-147FFCP PHASE1:Hg19::chr13:51913806..51913817,+#_709b708b702ba970e9d6241c87f75c22p2@SERPINE3
5.41e-147FFCP PHASE2:Hg19::chr13:99135322..99135327,-#_a8baddfc721fdf380f1c7de4194ea2c5p@chr13:99135322..99135327, -
5.41e-147FFCP PHASE1:Hg19::chr13:99135322..99135327,-#_a8baddfc721fdf380f1c7de4194ea2c5p@chr13:99135322..99135327, -
8.98e-131FFCP PHASE2:Hg19::chr13:51913893..51913901,+#_f822c893e6f3f7018b22203e39daed18p@chr13:51913893..51913901, +
8.98e-131FFCP PHASE1:Hg19::chr13:51913893..51913901,+#_f822c893e6f3f7018b22203e39daed18p@chr13:51913893..51913901, +
3.48e-118FFCP PHASE2:Hg19::chr11:109990513..109990520,-#_365c67e4a061f98b608baed0ba078761p@chr11:109990513..109990520, -
3.48e-118FFCP PHASE1:Hg19::chr11:109990513..109990520,-#_365c67e4a061f98b608baed0ba078761p@chr11:109990513..109990520, -
1.16e-117FFCP PHASE2:Hg19::chr5:70308745..70308754,-#_2eb3d08c4df74934424e68368c98148cp@chr5:70308745..70308754, -
1.16e-117FFCP PHASE1:Hg19::chr5:70308745..70308754,-#_2eb3d08c4df74934424e68368c98148cp@chr5:70308745..70308754, -
7.95e-99FFCP PHASE2:Hg19::chr11:61522844..61522875,+#_817f54cd88b70d9618ec4dd23e563b5cp2@C11orf9
7.95e-99FFCP PHASE1:Hg19::chr11:61522844..61522875,+#_817f54cd88b70d9618ec4dd23e563b5cp2@C11orf9
2.17e-98FFCP PHASE2:Hg19::chr2:235591306..235591328,+#_2f4b46d5a59d1637913df1ab58f6539dp@chr2:235591306..235591328, +
2.17e-98FFCP PHASE1:Hg19::chr2:235591306..235591328,+#_2f4b46d5a59d1637913df1ab58f6539dp@chr2:235591306..235591328, +
6.24e-88FFCP PHASE2:Hg19::chr11:61522820..61522823,+#_1a194f83961a5283da18f695ad7352d1p9@C11orf9
6.24e-88FFCP PHASE1:Hg19::chr11:61522820..61522823,+#_1a194f83961a5283da18f695ad7352d1p9@C11orf9
9.74e-88FFCP PHASE2:Hg19::chr8:75898210..75898219,+#_a98fa168b185a94a622fbb3c63dcf647p11@CRISPLD1
9.74e-88FFCP PHASE1:Hg19::chr8:75898210..75898219,+#_a98fa168b185a94a622fbb3c63dcf647p11@CRISPLD1
1.52e-87FFCP PHASE2:Hg19::chr2:45166274..45166281,-#_e960176834e654b0610e018fcc83239fp5@ENST00000437916
1.52e-87FFCP PHASE1:Hg19::chr2:45166274..45166281,-#_e960176834e654b0610e018fcc83239fp5@ENST00000437916
2.28e-85FFCP PHASE2:Hg19::chr13:51913819..51913838,+#_4eda99069e44ad83af3177231bfaeaf1p1@SERPINE3
2.28e-85FFCP PHASE1:Hg19::chr13:51913819..51913838,+#_4eda99069e44ad83af3177231bfaeaf1p1@SERPINE3
1.01e-74FFCP PHASE2:Hg19::chr3:69928426..69928436,+#_b0e0e941d82b27f5bf8fcb71295ba3bbp@chr3:69928426..69928436, +
1.01e-74FFCP PHASE1:Hg19::chr3:69928426..69928436,+#_b0e0e941d82b27f5bf8fcb71295ba3bbp@chr3:69928426..69928436, +
1.29e-74FFCP PHASE2:Hg19::chr3:69928404..69928418,+#_431697489e35dd0582923740aea2ef39p@chr3:69928404..69928418, +
1.29e-74FFCP PHASE1:Hg19::chr3:69928404..69928418,+#_431697489e35dd0582923740aea2ef39p@chr3:69928404..69928418, +
2.14e-74FFCP PHASE1:Hg19::chr22:37633537..37633546,-#_5c98fdd8bf11bb08f17ebe834a25ca1ap@chr22:37633537..37633546, -
2.14e-74FFCP PHASE2:Hg19::chr22:37633537..37633546,-#_5c98fdd8bf11bb08f17ebe834a25ca1ap@chr22:37633537..37633546, -
2.14e-74FFCP PHASE1:Hg19::chr6:168250971..168250985,+#_5c98fdd8bf11bb08f17ebe834a25ca1ap@chr6:168250971..168250985, +
2.14e-74FFCP PHASE2:Hg19::chr6:168250971..168250985,+#_5c98fdd8bf11bb08f17ebe834a25ca1ap@chr6:168250971..168250985, +
3.54e-74FFCP PHASE1:Hg19::chr1:43533230..43533270,+#_3778900dc05114de390718418afe5e6cp@chr1:43533230..43533270, +
3.54e-74FFCP PHASE2:Hg19::chr1:43533230..43533270,+#_3778900dc05114de390718418afe5e6cp@chr1:43533230..43533270, +
1.54e-66FFCP PHASE2:Hg19::chr21:36041275..36041282,+#_a3736b2053404b8532ca2b21a69cab11p5@CLIC6
1.54e-66FFCP PHASE1:Hg19::chr21:36041275..36041282,+#_a3736b2053404b8532ca2b21a69cab11p5@CLIC6
2.39e-66FFCP PHASE2:Hg19::chr13:51913997..51914020,+#_a2454988fdd1b38c74839c4e0df8b1a7p@chr13:51913997..51914020, +
2.39e-66FFCP PHASE1:Hg19::chr13:51913997..51914020,+#_a2454988fdd1b38c74839c4e0df8b1a7p@chr13:51913997..51914020, +
6.53e-66FFCP PHASE1:Hg19::chr6:168251000..168251007,+#_df3d74c0b6acc24beaa75507ee6fa3fdp@chr6:168251000..168251007, +
6.53e-66FFCP PHASE2:Hg19::chr6:168251000..168251007,+#_df3d74c0b6acc24beaa75507ee6fa3fdp@chr6:168251000..168251007, +
2.98e-60FFCP PHASE2:Hg19::chr13:99135278..99135298,-#_d604b5d3d19e121464fdd7ac7661dd21p@chr13:99135278..99135298, -
2.98e-60FFCP PHASE1:Hg19::chr13:99135278..99135298,-#_d604b5d3d19e121464fdd7ac7661dd21p@chr13:99135278..99135298, -
5.01e-55FFCP PHASE1:Hg19::chr3:69928371..69928385,+#_3e83d7732aaff91d2022af6b801a57edp@chr3:69928371..69928385, +
5.01e-55FFCP PHASE2:Hg19::chr3:69928371..69928385,+#_3e83d7732aaff91d2022af6b801a57edp@chr3:69928371..69928385, +
7.24e-55FFCP PHASE2:Hg19::chr14:87636652..87636657,-#_7a62c5d6170a3cfef091ae5e210d87dbp@chr14:87636652..87636657, -
7.24e-55FFCP PHASE1:Hg19::chr14:87636652..87636657,-#_7a62c5d6170a3cfef091ae5e210d87dbp@chr14:87636652..87636657, -
1.68e-53FFCP PHASE2:Hg19::chr2:235591286..235591298,+#_df9a21bcc7ea0acba96f2784c1519d6ep@chr2:235591286..235591298, +
1.68e-53FFCP PHASE1:Hg19::chr2:235591286..235591298,+#_df9a21bcc7ea0acba96f2784c1519d6ep@chr2:235591286..235591298, +
6.39e-53FFCP PHASE1:Hg19::chr11:119217442..119217445,-#_da803030c45f92d8990268805c7ac6d6p5@MFRP, p6@C1QTNF5
6.39e-53FFCP PHASE2:Hg19::chr16:84228961..84228982,+#_da803030c45f92d8990268805c7ac6d6p@chr16:84228961..84228982, +
6.39e-53FFCP PHASE1:Hg19::chr16:84228961..84228982,+#_da803030c45f92d8990268805c7ac6d6p@chr16:84228961..84228982, +
6.39e-53FFCP PHASE2:Hg19::chr11:119217442..119217445,-#_da803030c45f92d8990268805c7ac6d6p5@MFRP, p6@C1QTNF5
9.6e-51FFCP PHASE1:Hg19::chr21:36041264..36041274,+#_28d75cbeda9e392bc8602d22265d7230p3@CLIC6
9.6e-51FFCP PHASE2:Hg19::chr21:36041264..36041274,+#_28d75cbeda9e392bc8602d22265d7230p3@CLIC6
1.89e-50FFCP PHASE2:Hg19::chr11:75201755..75201762,-#_7ae24cc48dba963679e9734e6b5c569dp7@GDPD5
1.89e-50FFCP PHASE1:Hg19::chr11:75201755..75201762,-#_7ae24cc48dba963679e9734e6b5c569dp7@GDPD5
7.24e-50FFCP PHASE1:Hg19::chr11:119217421..119217435,-#_7c0cc97a0de9806c8ba429273699295cp4@MFRP, p5@C1QTNF5
7.24e-50FFCP PHASE2:Hg19::chr11:119217421..119217435,-#_7c0cc97a0de9806c8ba429273699295cp4@MFRP, p5@C1QTNF5
6.25e-45FFCP PHASE2:Hg19::chr17:932596..932605,-#_af209501ecd9ac4f61f320ee10c1b1a1p@chr17:932596..932605, -
6.25e-45FFCP PHASE1:Hg19::chr17:932596..932605,-#_af209501ecd9ac4f61f320ee10c1b1a1p@chr17:932596..932605, -
1.22e-44FFCP PHASE1:Hg19::chr20:52790691..52790695,-#_a95d7a32ffbc76dd7ad25972f5ab66bdp5@CYP24A1
1.22e-44FFCP PHASE2:Hg19::chr20:52790691..52790695,-#_a95d7a32ffbc76dd7ad25972f5ab66bdp5@CYP24A1
1.22e-44FFCP PHASE1:Hg19::chr22:38480132..38480159,-#_a95d7a32ffbc76dd7ad25972f5ab66bdp1@SLC16A8
1.22e-44FFCP PHASE2:Hg19::chr22:38480132..38480159,-#_a95d7a32ffbc76dd7ad25972f5ab66bdp1@SLC16A8
1.22e-44FFCP PHASE2:Hg19::chr17:932340..932343,-#_a95d7a32ffbc76dd7ad25972f5ab66bdp@chr17:932340..932343, -
1.22e-44FFCP PHASE1:Hg19::chr17:932340..932343,-#_a95d7a32ffbc76dd7ad25972f5ab66bdp@chr17:932340..932343, -
2.38e-44FFCP PHASE2:Hg19::chr3:98672197..98672201,+#_324e54e77b515efc94fce28f1d1d48c0p@chr3:98672197..98672201, +
2.38e-44FFCP PHASE1:Hg19::chr3:98672197..98672201,+#_324e54e77b515efc94fce28f1d1d48c0p@chr3:98672197..98672201, +
2.97e-44FFCP PHASE2:Hg19::chr3:183733654..183733680,-#_695dedc17a542cf7304ada27c8c5337ap@chr3:183733654..183733680, -
2.97e-44FFCP PHASE2:Hg19::chr9:127025189..127025200,+#_695dedc17a542cf7304ada27c8c5337ap1@ENST00000437461
2.97e-44FFCP PHASE1:Hg19::chr3:183733654..183733680,-#_695dedc17a542cf7304ada27c8c5337ap@chr3:183733654..183733680, -
2.97e-44FFCP PHASE1:Hg19::chr9:127025189..127025200,+#_695dedc17a542cf7304ada27c8c5337ap1@ENST00000437461
4.49e-44FFCP PHASE2:Hg19::chr9:140088882..140088898,-#_441a4ff5e28c974b9c784dbb66039d95p@chr9:140088882..140088898, -
4.49e-44FFCP PHASE1:Hg19::chr9:140088882..140088898,-#_441a4ff5e28c974b9c784dbb66039d95p@chr9:140088882..140088898, -
1.24e-43FFCP PHASE2:Hg19::chr14:28081776..28081788,+#_d42bdf0345f0a9b08268b8f1aea47aa2p1@LOC100505967
1.24e-43FFCP PHASE1:Hg19::chr14:28081776..28081788,+#_d42bdf0345f0a9b08268b8f1aea47aa2p1@LOC100505967
2.95e-43FFCP PHASE2:Hg19::chr2:45169172..45169177,+#_404a1f31e7455ffd4ec259d80457ca6cp11@SIX3
2.95e-43FFCP PHASE1:Hg19::chr2:45169172..45169177,+#_404a1f31e7455ffd4ec259d80457ca6cp11@SIX3
4.55e-43FFCP PHASE1:Hg19::chr5:33984786..33984820,-#_5e9c5a1e97f0330feb953e6e6fd777f9p2@SLC45A2
4.55e-43FFCP PHASE2:Hg19::chr5:33984786..33984820,-#_5e9c5a1e97f0330feb953e6e6fd777f9p2@SLC45A2
3.86e-41FFCP PHASE2:Hg19::chr16:68301840..68301845,+#_3c71154fb31c6d4baf046a2acb9e0a1dp@chr16:68301840..68301845, +
3.86e-41FFCP PHASE1:Hg19::chr16:68301840..68301845,+#_3c71154fb31c6d4baf046a2acb9e0a1dp@chr16:68301840..68301845, +
9.96e-41FFCP PHASE2:Hg19::chr19:49140255..49140268,-#_ba51aadfe2fac04d51b23060bf88e215p9@DBP
9.96e-41FFCP PHASE1:Hg19::chr19:49140255..49140268,-#_ba51aadfe2fac04d51b23060bf88e215p9@DBP
1.31e-40FFCP PHASE2:Hg19::chr12:52579447..52579461,-#_8a37880623142027c3d94e43d8017f42p6@KRT80
1.31e-40FFCP PHASE1:Hg19::chr12:52579447..52579461,-#_8a37880623142027c3d94e43d8017f42p6@KRT80
1.49e-40FFCP PHASE2:Hg19::chr4:23886471..23886501,-#_9f315c6767650911a66468fa36f79e67p5@PPARGC1A
1.49e-40FFCP PHASE1:Hg19::chr4:23886471..23886501,-#_9f315c6767650911a66468fa36f79e67p5@PPARGC1A
1.71e-40FFCP PHASE1:Hg19::chr11:119217318..119217346,-#_837446a760b70bf83cc12df1bfa3dbaap2@MFRP
1.71e-40FFCP PHASE2:Hg19::chr11:119217318..119217346,-#_837446a760b70bf83cc12df1bfa3dbaap2@MFRP
1.96e-40FFCP PHASE2:Hg19::chr11:119217405..119217420,-#_0f5d9f7ab46f8fd5940703e4829e98e8p3@C1QTNF5, p3@MFRP
1.96e-40FFCP PHASE1:Hg19::chr11:119217405..119217420,-#_0f5d9f7ab46f8fd5940703e4829e98e8p3@C1QTNF5, p3@MFRP
2.93e-40FFCP PHASE1:Hg19::chr8:144905532..144905541,-#_156168d86eaaddb0862f666276a6cc1ep6@PUF60
2.93e-40FFCP PHASE2:Hg19::chr8:144905532..144905541,-#_156168d86eaaddb0862f666276a6cc1ep6@PUF60
3.83e-40FFCP PHASE2:Hg19::chr2:45162900..45162914,-#_e73fb7584514f60078bd0db15f4ea965p1@ENST00000432125
3.83e-40FFCP PHASE1:Hg19::chr2:45162900..45162914,-#_e73fb7584514f60078bd0db15f4ea965p1@ENST00000432125
6.54e-40FFCP PHASE2:Hg19::chr9:73483992..73484003,-#_42ceeaa6da93b18efcb88de1ca31d9ccp6@TRPM3
6.54e-40FFCP PHASE1:Hg19::chr9:73483992..73484003,-#_42ceeaa6da93b18efcb88de1ca31d9ccp6@TRPM3
1.11e-38FFCP PHASE1:Hg19::chr11:67776077..67776088,+#_245a66603b573894cedf8ed1070202b6p5@ALDH3B1
1.11e-38FFCP PHASE2:Hg19::chr11:67776077..67776088,+#_245a66603b573894cedf8ed1070202b6p5@ALDH3B1

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