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UBERON:0003069

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Name:otic placode
Definition:"A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII" [NBK:NBK53175]
Xrefs:
links:

AAO:0011079
EFO:0003429
EHDAA:506
EHDAA2:0001339
EMAPA:16195
ncithesaurus:Otic_Placodes
TAO:0000138
VHOG:0000235
XAO:0000223

ZFA:0000138
Synonyms: "auditory placode" RELATED []
"ear placode" RELATED []
"ear/otic placode" RELATED []
Comments:With the exception of the pigment cells of the stria vascularis and the secretory epithelium of the cochlea, which are of neural crest origin, all compo- nents of the inner ear derive from the otic placode. In most species the thickening of the ectoderm into a placode occurs in a region adjacent to rhombomere 5 (reviewed in Ohyama et al., 2007), while in amphibians the otic placode is centered onto rhombomere 4 (Ruiz i Altaba and Jessell, 1991).[NBK53175]
Alt_id: UBERON:XAO_0000223-ZFA_0000138
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0003067(dorsolateral placode),UBERON:0005085(ectodermal placode)
part_of:UBERON:0001690(ear)



Children

develops from:UBERON:0009123 (otic cup)
part of:UBERON:0003249 (epithelium of otic placode)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology




Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003069 (otic placode), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.87e-86FFCP PHASE2:Mm9::chr18:66033526..66033539,-#_79a6708211b885bd34d9bea04e5ffea8p@chr18:66033526..66033539, -
1.87e-86FFCP PHASE2:Mm9::chr14:31283085..31283097,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:31283085..31283097, -
1.87e-86FFCP PHASE1:Mm9::chr11:8405038..8405048,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:8405038..8405048, -
1.87e-86FFCP PHASE2:Mm9::chr7:29733825..29733837,-#_79a6708211b885bd34d9bea04e5ffea8p@chr7:29733825..29733837, -
1.87e-86FFCP PHASE2:Mm9::chr3:69811590..69811601,+#_79a6708211b885bd34d9bea04e5ffea8p1@Otol1
1.87e-86FFCP PHASE2:Mm9::chr19:22767090..22767099,+#_79a6708211b885bd34d9bea04e5ffea8p18@Trpm3
1.87e-86FFCP PHASE2:Mm9::chr18:81314626..81314636,+#_79a6708211b885bd34d9bea04e5ffea8p@chr18:81314626..81314636, +
1.87e-86FFCP PHASE2:Mm9::chr2:75320183..75320189,+#_79a6708211b885bd34d9bea04e5ffea8p@chr2:75320183..75320189, +
1.87e-86FFCP PHASE1:Mm9::chr1:60561636..60561645,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:60561636..60561645, -
1.87e-86FFCP PHASE1:Mm9::chr14:63099970..63099980,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:63099970..63099980, -
1.87e-86FFCP PHASE2:Mm9::chr2:121206695..121206711,-#_79a6708211b885bd34d9bea04e5ffea8p1@Strc
1.87e-86FFCP PHASE1:Mm9::chr6:30619443..30619450,-#_79a6708211b885bd34d9bea04e5ffea8p13@Tsga14
1.87e-86FFCP PHASE1:Mm9::chr17:31335869..31335899,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tmprss3
1.87e-86FFCP PHASE2:Mm9::chr6:113251606..113251613,+#_79a6708211b885bd34d9bea04e5ffea8p@chr6:113251606..113251613, +
1.87e-86FFCP PHASE2:Mm9::chr2:170417150..170417155,-#_79a6708211b885bd34d9bea04e5ffea8p@chr2:170417150..170417155, -
1.87e-86FFCP PHASE1:Mm9::chr6:86745686..86745727,-#_79a6708211b885bd34d9bea04e5ffea8p@chr6:86745686..86745727, -
1.87e-86FFCP PHASE1:Mm9::chr3:69811590..69811601,+#_79a6708211b885bd34d9bea04e5ffea8p1@Otol1
1.87e-86FFCP PHASE2:Mm9::chr16:96494788..96494801,+#_79a6708211b885bd34d9bea04e5ffea8p12@B3galt5
1.87e-86FFCP PHASE1:Mm9::chr14:47293487..47293493,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:47293487..47293493, -
1.87e-86FFCP PHASE1:Mm9::chr12:77084875..77084885,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:77084875..77084885, +
1.87e-86FFCP PHASE2:Mm9::chr12:13508015..13508019,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:13508015..13508019, +
1.87e-86FFCP PHASE2:Mm9::chr16:45693840..45693856,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tmprss7
1.87e-86FFCP PHASE2:Mm9::chr3:154459231..154459240,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:154459231..154459240, +
1.87e-86FFCP PHASE2:Mm9::chr2:67011956..67011967,+#_79a6708211b885bd34d9bea04e5ffea8p1@Gm1322
1.87e-86FFCP PHASE2:Mm9::chr9:42207998..42208009,-#_79a6708211b885bd34d9bea04e5ffea8p6@Tecta
1.87e-86FFCP PHASE1:Mm9::chr13:76964459..76964469,+#_79a6708211b885bd34d9bea04e5ffea8p15@Mctp1
1.87e-86FFCP PHASE1:Mm9::chr9:92087926..92087938,+#_79a6708211b885bd34d9bea04e5ffea8p2@Plscr5
1.87e-86FFCP PHASE2:Mm9::chrX:154140781..154140788,+#_79a6708211b885bd34d9bea04e5ffea8p@chrX:154140781..154140788, +
1.87e-86FFCP PHASE1:Mm9::chr1:172843847..172843880,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843847..172843880, -
1.87e-86FFCP PHASE1:Mm9::chr12:13508046..13508055,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:13508046..13508055, +
1.87e-86FFCP PHASE2:Mm9::chr10:107349392..107349413,-#_79a6708211b885bd34d9bea04e5ffea8p2@Otogl
1.87e-86FFCP PHASE1:Mm9::chr9:42207998..42208009,-#_79a6708211b885bd34d9bea04e5ffea8p6@Tecta
1.87e-86FFCP PHASE1:Mm9::chr1:94627290..94627299,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:94627290..94627299, -
1.87e-86FFCP PHASE1:Mm9::chr13:37195838..37195870,-#_79a6708211b885bd34d9bea04e5ffea8p@chr13:37195838..37195870, -
1.87e-86FFCP PHASE2:Mm9::chr13:43699228..43699239,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:43699228..43699239, +
1.87e-86FFCP PHASE2:Mm9::chr15:58022966..58022995,-#_79a6708211b885bd34d9bea04e5ffea8p@chr15:58022966..58022995, -
1.87e-86FFCP PHASE2:Mm9::chr9:42207397..42207408,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42207397..42207408, -
1.87e-86FFCP PHASE1:Mm9::chr8:125802236..125802251,-#_79a6708211b885bd34d9bea04e5ffea8p3@Fanca
1.87e-86FFCP PHASE1:Mm9::chr2:121206677..121206683,-#_79a6708211b885bd34d9bea04e5ffea8p3@Strc
1.87e-86FFCP PHASE1:Mm9::chr10:107349309..107349318,-#_79a6708211b885bd34d9bea04e5ffea8p4@Otogl
1.87e-86FFCP PHASE2:Mm9::chr13:78322383..78322395,-#_79a6708211b885bd34d9bea04e5ffea8p2@uc007rhb.1
1.87e-86FFCP PHASE2:Mm9::chr1:182528388..182528403,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:182528388..182528403, +
1.87e-86FFCP PHASE1:Mm9::chr16:45693840..45693856,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tmprss7
1.87e-86FFCP PHASE1:Mm9::chr9:42207397..42207408,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42207397..42207408, -
1.87e-86FFCP PHASE1:Mm9::chr1:78523144..78523177,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:78523144..78523177, +
1.87e-86FFCP PHASE2:Mm9::chr9:41495920..41495928,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:41495920..41495928, -
1.87e-86FFCP PHASE1:Mm9::chr11:11599532..11599539,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:11599532..11599539, -
1.87e-86FFCP PHASE2:Mm9::chr4:133802857..133802884,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:133802857..133802884, +
1.87e-86FFCP PHASE1:Mm9::chr3:154459246..154459253,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:154459246..154459253, +
1.87e-86FFCP PHASE2:Mm9::chr15:65641779..65641790,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:65641779..65641790, +
1.87e-86FFCP PHASE1:Mm9::chr5:147854240..147854249,-#_79a6708211b885bd34d9bea04e5ffea8p@chr5:147854240..147854249, -
1.87e-86FFCP PHASE1:Mm9::chr18:42158627..42158630,-#_79a6708211b885bd34d9bea04e5ffea8p@chr18:42158627..42158630, -
1.87e-86FFCP PHASE1:Mm9::chr2:53464168..53464175,+#_79a6708211b885bd34d9bea04e5ffea8p@chr2:53464168..53464175, +
1.87e-86FFCP PHASE2:Mm9::chr8:13425469..13425503,+#_79a6708211b885bd34d9bea04e5ffea8p@chr8:13425469..13425503, +
1.87e-86FFCP PHASE2:Mm9::chr10:80806020..80806031,-#_79a6708211b885bd34d9bea04e5ffea8p3@Gipc3
1.87e-86FFCP PHASE1:Mm9::chr6:29428397..29428407,-#_79a6708211b885bd34d9bea04e5ffea8p@chr6:29428397..29428407, -
1.87e-86FFCP PHASE1:Mm9::chr17:27252925..27252939,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:27252925..27252939, +
1.87e-86FFCP PHASE2:Mm9::chr10:67371994..67372010,+#_79a6708211b885bd34d9bea04e5ffea8p@chr10:67371994..67372010, +
1.87e-86FFCP PHASE1:Mm9::chr4:63079735..63079745,-#_79a6708211b885bd34d9bea04e5ffea8p@chr4:63079735..63079745, -
1.87e-86FFCP PHASE1:Mm9::chr13:78322383..78322395,-#_79a6708211b885bd34d9bea04e5ffea8p2@uc007rhb.1
1.87e-86FFCP PHASE2:Mm9::chr15:89215333..89215341,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:89215333..89215341, +
1.87e-86FFCP PHASE2:Mm9::chr3:31585340..31585360,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:31585340..31585360, +
1.87e-86FFCP PHASE2:Mm9::chr1:172843796..172843799,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843796..172843799, -
1.87e-86FFCP PHASE2:Mm9::chr5:30710455..30710464,-#_79a6708211b885bd34d9bea04e5ffea8p9@Otof
1.87e-86FFCP PHASE2:Mm9::chr15:97806034..97806061,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:97806034..97806061, +
1.87e-86FFCP PHASE2:Mm9::chr14:20649897..20649907,+#_79a6708211b885bd34d9bea04e5ffea8p@chr14:20649897..20649907, +
1.87e-86FFCP PHASE2:Mm9::chr10:108316802..108316807,-#_79a6708211b885bd34d9bea04e5ffea8p@chr10:108316802..108316807, -
1.87e-86FFCP PHASE1:Mm9::chr6:113251606..113251613,+#_79a6708211b885bd34d9bea04e5ffea8p@chr6:113251606..113251613, +
1.87e-86FFCP PHASE1:Mm9::chr4:130461150..130461185,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:130461150..130461185, +
1.87e-86FFCP PHASE1:Mm9::chr17:13983160..13983167,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983160..13983167, +
1.87e-86FFCP PHASE2:Mm9::chr14:63099970..63099980,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:63099970..63099980, -
1.87e-86FFCP PHASE2:Mm9::chr19:10536767..10536777,-#_79a6708211b885bd34d9bea04e5ffea8p@chr19:10536767..10536777, -
1.87e-86FFCP PHASE2:Mm9::chr9:42207852..42207876,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tecta
1.87e-86FFCP PHASE1:Mm9::chr8:13425469..13425503,+#_79a6708211b885bd34d9bea04e5ffea8p@chr8:13425469..13425503, +
1.87e-86FFCP PHASE1:Mm9::chr19:55255289..55255299,+#_79a6708211b885bd34d9bea04e5ffea8p2@Tectb
1.87e-86FFCP PHASE1:Mm9::chr15:89215319..89215330,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:89215319..89215330, +
1.87e-86FFCP PHASE2:Mm9::chr8:125802236..125802251,-#_79a6708211b885bd34d9bea04e5ffea8p3@Fanca
1.87e-86FFCP PHASE1:Mm9::chr16:93971357..93971363,-#_79a6708211b885bd34d9bea04e5ffea8p@chr16:93971357..93971363, -
1.87e-86FFCP PHASE2:Mm9::chr3:35012397..35012405,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:35012397..35012405, +
1.87e-86FFCP PHASE2:Mm9::chr4:115556972..115556979,+#_79a6708211b885bd34d9bea04e5ffea8p3@Kncn
1.87e-86FFCP PHASE2:Mm9::chr17:13983102..13983126,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983102..13983126, +
1.87e-86FFCP PHASE1:Mm9::chr9:42207852..42207876,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tecta
1.87e-86FFCP PHASE1:Mm9::chr7:29733825..29733837,-#_79a6708211b885bd34d9bea04e5ffea8p@chr7:29733825..29733837, -
1.87e-86FFCP PHASE1:Mm9::chr1:93235228..93235249,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:93235228..93235249, +
1.87e-86FFCP PHASE2:Mm9::chr9:42206730..42206739,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206730..42206739, -
1.87e-86FFCP PHASE2:Mm9::chr13:78257454..78257465,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:78257454..78257465, +
1.87e-86FFCP PHASE2:Mm9::chr13:48087761..48087775,-#_79a6708211b885bd34d9bea04e5ffea8p@chr13:48087761..48087775, -
1.87e-86FFCP PHASE1:Mm9::chr7:109052262..109052291,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tomt
1.87e-86FFCP PHASE1:Mm9::chr2:152453066..152453075,-#_79a6708211b885bd34d9bea04e5ffea8p@chr2:152453066..152453075, -
1.87e-86FFCP PHASE1:Mm9::chr14:102297728..102297742,+#_79a6708211b885bd34d9bea04e5ffea8p@chr14:102297728..102297742, +
1.87e-86FFCP PHASE2:Mm9::chr3:69811606..69811616,+#_79a6708211b885bd34d9bea04e5ffea8p2@Otol1
1.87e-86FFCP PHASE1:Mm9::chr5:28035962..28035983,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:28035962..28035983, +
1.87e-86FFCP PHASE1:Mm9::chr4:101908153..101908163,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:101908153..101908163, +
1.87e-86FFCP PHASE2:Mm9::chr18:81327205..81327211,+#_79a6708211b885bd34d9bea04e5ffea8p@chr18:81327205..81327211, +
1.87e-86FFCP PHASE2:Mm9::chr11:11599532..11599539,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:11599532..11599539, -
1.87e-86FFCP PHASE2:Mm9::chr12:77084875..77084885,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:77084875..77084885, +
1.87e-86FFCP PHASE1:Mm9::chr9:42206730..42206739,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206730..42206739, -
1.87e-86FFCP PHASE1:Mm9::chr1:63733478..63733491,-#_79a6708211b885bd34d9bea04e5ffea8p1@Dytn
1.87e-86FFCP PHASE2:Mm9::chr1:93218682..93218691,+#_79a6708211b885bd34d9bea04e5ffea8p2@Espnl
1.87e-86FFCP PHASE2:Mm9::chr11:4689776..4689785,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:4689776..4689785, -