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Coexpression cluster:C77

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Full id: C77_Saos2_osteosarcoma_Neutrophils_Natural_Chondrocyte_Basophils_CD8



Phase1 CAGE Peaks

Hg19::chr10:54411290..54411295,-p@chr10:54411290..54411295
-
Hg19::chr11:124478164..124478168,-p@chr11:124478164..124478168
-
Hg19::chr11:124479851..124479862,-p@chr11:124479851..124479862
-
Hg19::chr11:124480065..124480072,-p@chr11:124480065..124480072
-
Hg19::chr11:124480073..124480086,-p@chr11:124480073..124480086
-
Hg19::chr11:124481316..124481334,+p1@PANX3
Hg19::chr11:124481361..124481366,+p2@PANX3
Hg19::chr11:124489771..124489792,+p@chr11:124489771..124489792
+
Hg19::chr11:126573090..126573097,+p@chr11:126573090..126573097
+
Hg19::chr11:126573105..126573118,+p@chr11:126573105..126573118
+
Hg19::chr11:131213225..131213274,+p@chr11:131213225..131213274
+
Hg19::chr11:299519..299533,-p1@IFITM5
Hg19::chr11:30911556..30911574,+p@chr11:30911556..30911574
+
Hg19::chr11:46326686..46326700,+p@chr11:46326686..46326700
+
Hg19::chr11:81619863..81619881,+p@chr11:81619863..81619881
+
Hg19::chr11:85416537..85416545,-p22@SYTL2
Hg19::chr11:85416548..85416560,-p18@SYTL2
Hg19::chr11:92613787..92613796,+p@chr11:92613787..92613796
+
Hg19::chr11:92613813..92613863,+p@chr11:92613813..92613863
+
Hg19::chr11:93129900..93129911,+p@chr11:93129900..93129911
+
Hg19::chr12:49366362..49366379,-p@chr12:49366362..49366379
-
Hg19::chr12:49366390..49366401,-p@chr12:49366390..49366401
-
Hg19::chr12:49366435..49366452,-p@chr12:49366435..49366452
-
Hg19::chr12:53721918..53721923,-p@chr12:53721918..53721923
-
Hg19::chr12:53730147..53730177,-p2@SP7
Hg19::chr12:53730178..53730189,-p3@SP7
Hg19::chr12:67914694..67914707,+p@chr12:67914694..67914707
+
Hg19::chr13:42264610..42264621,-p@chr13:42264610..42264621
-
Hg19::chr13:42264908..42264914,-p@chr13:42264908..42264914
-
Hg19::chr13:42267088..42267096,-p@chr13:42267088..42267096
-
Hg19::chr13:42269057..42269068,-p3@AK130122
Hg19::chr13:42269075..42269089,-p1@AK130122
Hg19::chr13:42269101..42269110,-p4@AK130122
Hg19::chr13:42269136..42269148,-p2@AK130122
Hg19::chr14:28314513..28314526,-p1@ENST00000555797
Hg19::chr15:30360639..30360648,-p@chr15:30360639..30360648
-
Hg19::chr15:30360803..30360815,-p@chr15:30360803..30360815
-
Hg19::chr16:53706815..53706819,-p@chr16:53706815..53706819
-
Hg19::chr16:53707116..53707125,-p@chr16:53707116..53707125
-
Hg19::chr16:57147279..57147287,+p3@AF542551
p3@BC010627
Hg19::chr16:70731167..70731181,-p@chr16:70731167..70731181
-
Hg19::chr16:70731292..70731335,-p@chr16:70731292..70731335
-
Hg19::chr17:1932231..1932269,+p@chr17:1932231..1932269
+
Hg19::chr17:4705621..4705645,-p@chr17:4705621..4705645
-
Hg19::chr17:79965744..79965750,+p11@ASPSCR1
Hg19::chr17:79965883..79965891,+p@chr17:79965883..79965891
+
Hg19::chr17:79965892..79965924,+p@chr17:79965892..79965924
+
Hg19::chr17:79965930..79965938,+p@chr17:79965930..79965938
+
Hg19::chr17:79965942..79965947,+p@chr17:79965942..79965947
+
Hg19::chr17:79966486..79966493,+p@chr17:79966486..79966493
+
Hg19::chr17:79966585..79966594,+p@chr17:79966585..79966594
+
Hg19::chr17:79966610..79966637,+p@chr17:79966610..79966637
+
Hg19::chr17:79966642..79966666,+p@chr17:79966642..79966666
+
Hg19::chr17:79966939..79966954,+p@chr17:79966939..79966954
+
Hg19::chr17:79967254..79967267,+p@chr17:79967254..79967267
+
Hg19::chr17:79968448..79968454,+p@chr17:79968448..79968454
+
Hg19::chr17:79968458..79968470,+p@chr17:79968458..79968470
+
Hg19::chr17:79968480..79968490,+p@chr17:79968480..79968490
+
Hg19::chr17:79968522..79968530,+p@chr17:79968522..79968530
+
Hg19::chr17:79968630..79968635,+p@chr17:79968630..79968635
+
Hg19::chr17:79968655..79968672,+p@chr17:79968655..79968672
+
Hg19::chr17:79969860..79969871,+p@chr17:79969860..79969871
+
Hg19::chr18:66061928..66061937,-p@chr18:66061928..66061937
-
Hg19::chr18:66061970..66061982,-p@chr18:66061970..66061982
-
Hg19::chr19:28145289..28145296,-p@chr19:28145289..28145296
-
Hg19::chr19:28163893..28163904,+p@chr19:28163893..28163904
+
Hg19::chr19:28164112..28164118,+p@chr19:28164112..28164118
+
Hg19::chr19:28185172..28185189,-p@chr19:28185172..28185189
-
Hg19::chr19:28198009..28198037,-p@chr19:28198009..28198037
-
Hg19::chr19:28198123..28198149,+p@chr19:28198123..28198149
+
Hg19::chr19:28198179..28198195,+p@chr19:28198179..28198195
+
Hg19::chr19:28198206..28198222,+p@chr19:28198206..28198222
+
Hg19::chr19:28202503..28202508,-p@chr19:28202503..28202508
-
Hg19::chr19:28202519..28202528,-p@chr19:28202519..28202528
-
Hg19::chr19:28236792..28236797,+p@chr19:28236792..28236797
+
Hg19::chr19:28237057..28237073,+p@chr19:28237057..28237073
+
Hg19::chr19:28242224..28242230,+p@chr19:28242224..28242230
+
Hg19::chr19:28248054..28248062,+p@chr19:28248054..28248062
+
Hg19::chr19:28260754..28260759,+p@chr19:28260754..28260759
+
Hg19::chr19:28262882..28262886,+p@chr19:28262882..28262886
+
Hg19::chr19:28269266..28269269,+p@chr19:28269266..28269269
+
Hg19::chr19:28271083..28271089,+p@chr19:28271083..28271089
+
Hg19::chr19:28271937..28271942,+p@chr19:28271937..28271942
+
Hg19::chr19:28272010..28272016,+p@chr19:28272010..28272016
+
Hg19::chr19:3314450..3314461,+p@chr19:3314450..3314461
+
Hg19::chr19:45821290..45821301,-p@chr19:45821290..45821301
-
Hg19::chr19:45821324..45821328,-p@chr19:45821324..45821328
-
Hg19::chr1:105493789..105493826,-p@chr1:105493789..105493826
-
Hg19::chr1:112316957..112316974,+p@chr1:112316957..112316974
+
Hg19::chr1:16343894..16343914,-p@chr1:16343894..16343914
-
Hg19::chr1:16343915..16343936,-p@chr1:16343915..16343936
-
Hg19::chr1:16343937..16343946,-p@chr1:16343937..16343946
-
Hg19::chr1:199050050..199050059,-p@chr1:199050050..199050059
-
Hg19::chr1:199050926..199050944,-p@chr1:199050926..199050944
-
Hg19::chr1:21835908..21835926,+p1@ALPL
Hg19::chr1:21880493..21880518,+p4@ALPL
Hg19::chr1:21880519..21880528,+p11@ALPL
Hg19::chr1:21890586..21890595,+p9@ALPL
Hg19::chr1:21894015..21894027,+p@chr1:21894015..21894027
+
Hg19::chr1:21894055..21894060,+p@chr1:21894055..21894060
+
Hg19::chr1:21904551..21904569,-p@chr1:21904551..21904569
-
Hg19::chr1:21912937..21912944,+p2@ENST00000457706
Hg19::chr1:21912975..21912983,+p1@ENST00000457706
Hg19::chr1:25291275..25291301,-p12@RUNX3
Hg19::chr1:39992756..39992784,-p@chr1:39992756..39992784
-
Hg19::chr1:41868813..41868817,-p@chr1:41868813..41868817
-
Hg19::chr1:52116793..52116805,+p@chr1:52116793..52116805
+
Hg19::chr1:62392583..62392613,+p@chr1:62392583..62392613
+
Hg19::chr1:62392630..62392651,+p@chr1:62392630..62392651
+
Hg19::chr1:77864109..77864116,+p@chr1:77864109..77864116
+
Hg19::chr20:17519265..17519274,-p@chr20:17519265..17519274
-
Hg19::chr20:17519297..17519304,-p@chr20:17519297..17519304
-
Hg19::chr20:4444563..4444585,+p@chr20:4444563..4444585
+
Hg19::chr20:4444611..4444628,+p@chr20:4444611..4444628
+
Hg19::chr20:4451158..4451164,-p@chr20:4451158..4451164
-
Hg19::chr20:58676515..58676524,+p@chr20:58676515..58676524
+
Hg19::chr20:58676530..58676545,+p@chr20:58676530..58676545
+
Hg19::chr2:121684363..121684405,+p@chr2:121684363..121684405
+
Hg19::chr2:128896491..128896497,+p@chr2:128896491..128896497
+
Hg19::chr2:128896543..128896553,+p@chr2:128896543..128896553
+
Hg19::chr2:190240072..190240096,+p@chr2:190240072..190240096
+
Hg19::chr2:190240113..190240131,+p@chr2:190240113..190240131
+
Hg19::chr2:190240185..190240190,+p@chr2:190240185..190240190
+
Hg19::chr2:190245902..190245918,-p@chr2:190245902..190245918
-
Hg19::chr2:200470609..200470616,-p@chr2:200470609..200470616
-
Hg19::chr2:200677330..200677348,+p@chr2:200677330..200677348
+
Hg19::chr2:37593641..37593648,+p@chr2:37593641..37593648
+
Hg19::chr2:37593656..37593667,+p@chr2:37593656..37593667
+
Hg19::chr2:38466754..38466766,-p2@ENST00000450854
Hg19::chr2:38466814..38466823,-p8@ENST00000450854
Hg19::chr2:54252811..54252825,-p@chr2:54252811..54252825
-
Hg19::chr2:71791188..71791195,+p@chr2:71791188..71791195
+
Hg19::chr2:8960249..8960254,-p@chr2:8960249..8960254
-
Hg19::chr3:141678730..141678768,-p@chr3:141678730..141678768
-
Hg19::chr3:149824497..149824506,-p@chr3:149824497..149824506
-
Hg19::chr3:149824547..149824554,-p@chr3:149824547..149824554
-
Hg19::chr3:180588303..180588310,-p1@CCDC39
Hg19::chr3:41723047..41723059,-p5@ULK4
Hg19::chr3:55016696..55016715,-p@chr3:55016696..55016715
-
Hg19::chr3:55016721..55016732,-p@chr3:55016721..55016732
-
Hg19::chr3:58021410..58021424,+p@chr3:58021410..58021424
+
Hg19::chr4:123392011..123392012,+p@chr4:123392011..123392012
+
Hg19::chr4:145430542..145430557,-p@chr4:145430542..145430557
-
Hg19::chr4:15964182..15964193,+p2@CU693033
Hg19::chr4:15964231..15964260,+p1@CU693033
Hg19::chr4:15964293..15964341,+p4@CU693033
Hg19::chr4:15964788..15964805,-p1@FGFBP2
Hg19::chr4:15964806..15964817,-p3@FGFBP2
Hg19::chr4:15964830..15964851,-p2@FGFBP2
Hg19::chr4:16020432..16020477,-p@chr4:16020432..16020477
-
Hg19::chr4:16020500..16020547,-p@chr4:16020500..16020547
-
Hg19::chr4:16027038..16027047,-p@chr4:16027038..16027047
-
Hg19::chr4:188536760..188536764,-p@chr4:188536760..188536764
-
Hg19::chr4:188536783..188536788,-p@chr4:188536783..188536788
-
Hg19::chr4:188536806..188536817,-p@chr4:188536806..188536817
-
Hg19::chr4:188536873..188536891,-p@chr4:188536873..188536891
-
Hg19::chr4:189321717..189321731,+p2@ENST00000512839
p2@ENST00000513313
p2@uc003izo.1
Hg19::chr4:189321732..189321736,+p7@ENST00000512839
p7@ENST00000513313
p7@uc003izo.1
Hg19::chr4:189321921..189321935,+p4@ENST00000512839
p4@ENST00000513313
p4@uc003izo.1
Hg19::chr4:189321956..189321963,+p6@ENST00000512839
p6@ENST00000513313
p6@uc003izo.1
Hg19::chr4:35027177..35027183,-p@chr4:35027177..35027183
-
Hg19::chr4:41614752..41614765,+p27@LIMCH1
Hg19::chr4:57931672..57931693,-p4@ENST00000512512
Hg19::chr4:66535152..66535180,+p3@LOC100144602
Hg19::chr4:77506733..77506743,+p@chr4:77506733..77506743
+
Hg19::chr4:88653561..88653570,-p1@ENST00000506480
Hg19::chr4:88654323..88654347,-p@chr4:88654323..88654347
-
Hg19::chr4:88666648..88666655,-p@chr4:88666648..88666655
-
Hg19::chr4:88720698..88720722,+p1@IBSP
Hg19::chr4:88723803..88723839,+p@chr4:88723803..88723839
+
Hg19::chr4:88727274..88727278,+p@chr4:88727274..88727278
+
Hg19::chr4:88731810..88731821,+p@chr4:88731810..88731821
+
Hg19::chr4:88731854..88731869,+p@chr4:88731854..88731869
+
Hg19::chr4:88731871..88731877,+p@chr4:88731871..88731877
+
Hg19::chr4:88731888..88731889,+p@chr4:88731888..88731889
+
Hg19::chr4:88732513..88732528,+p@chr4:88732513..88732528
+
Hg19::chr4:88732806..88732816,+p@chr4:88732806..88732816
+
Hg19::chr5:82307578..82307601,-p@chr5:82307578..82307601
-
Hg19::chr5:86679358..86679365,+p@chr5:86679358..86679365
+
Hg19::chr6:113772872..113772888,-p@chr6:113772872..113772888
-
Hg19::chr6:116447293..116447325,-p1@COL10A1
Hg19::chr6:143447228..143447237,+p16@AIG1
Hg19::chr6:143447268..143447286,+p4@AIG1
Hg19::chr6:143447290..143447299,+p17@AIG1
Hg19::chr6:143447300..143447316,+p8@AIG1
Hg19::chr6:143447322..143447336,+p11@AIG1
Hg19::chr6:155427848..155427862,+p@chr6:155427848..155427862
+
Hg19::chr6:161454830..161454839,+p@chr6:161454830..161454839
+
Hg19::chr6:23228832..23228835,+p@chr6:23228832..23228835
+
Hg19::chr6:23228836..23228864,+p@chr6:23228836..23228864
+
Hg19::chr6:41613840..41613845,+p18@MDFI
Hg19::chr6:45295874..45295877,+p47@RUNX2
Hg19::chr6:45322890..45322895,+p@chr6:45322890..45322895
+
Hg19::chr6:45382521..45382525,+p@chr6:45382521..45382525
+
Hg19::chr6:81430111..81430117,+p@chr6:81430111..81430117
+
Hg19::chr6:81435467..81435479,+p@chr6:81435467..81435479
+
Hg19::chr7:131582395..131582410,+p1@ENST00000452219
Hg19::chr7:131583321..131583328,-p@chr7:131583321..131583328
-
Hg19::chr7:25370183..25370193,+p@chr7:25370183..25370193
+
Hg19::chr7:48078148..48078160,-p@chr7:48078148..48078160
-
Hg19::chr7:78161666..78161675,-p@chr7:78161666..78161675
-
Hg19::chr7:80000207..80000217,+p@chr7:80000207..80000217
+
Hg19::chr8:104215580..104215589,-p1@ENST00000523915
Hg19::chr8:134020867..134020882,-p@chr8:134020867..134020882
-
Hg19::chr8:134020899..134020917,-p@chr8:134020899..134020917
-
Hg19::chr8:134021151..134021176,-p@chr8:134021151..134021176
-
Hg19::chr8:134021602..134021610,+p@chr8:134021602..134021610
+
Hg19::chr8:134029743..134029754,+p34@TG
Hg19::chr8:134029937..134029944,+p22@TG
Hg19::chr8:134104319..134104347,-p@chr8:134104319..134104347
-
Hg19::chr8:134128500..134128506,+p@chr8:134128500..134128506
+
Hg19::chr8:60090206..60090207,+p@chr8:60090206..60090207
+
Hg19::chr8:64349734..64349746,+p@chr8:64349734..64349746
+
Hg19::chr8:72504214..72504256,-p1@ENST00000518177
Hg19::chr8:97570368..97570378,+p@chr8:97570368..97570378
+
Hg19::chr9:118246509..118246532,+p@chr9:118246509..118246532
+
Hg19::chr9:29940198..29940204,+p@chr9:29940198..29940204
+
Hg19::chr9:29941904..29941908,+p@chr9:29941904..29941908
+
Hg19::chr9:29942046..29942058,+p@chr9:29942046..29942058
+
Hg19::chr9:29942099..29942136,+p@chr9:29942099..29942136
+
Hg19::chr9:29942164..29942166,+p@chr9:29942164..29942166
+
Hg19::chr9:29963867..29963872,+p@chr9:29963867..29963872
+
Hg19::chr9:72436290..72436302,-p@chr9:72436290..72436302
-
Hg19::chr9:72436304..72436310,-p@chr9:72436304..72436310
-
Hg19::chr9:72436332..72436343,-p@chr9:72436332..72436343
-
Hg19::chr9:97952157..97952178,-p1@AF086119
Hg19::chr9:97968566..97968576,-p@chr9:97968566..97968576
-
Hg19::chrX:57619083..57619113,+p1@ZXDB
Hg19::chrX:57930371..57930380,-p@chrX:57930371..57930380
-
Hg19::chrX:57933412..57933415,-p@chrX:57933412..57933415
-
Hg19::chrX:57934585..57934628,-p@chrX:57934585..57934628
-
Hg19::chrX:57936237..57936264,-p1@ZXDA
Hg19::chrX:58052946..58052954,+p@chrX:58052946..58052954
+
Hg19::chrX:58168137..58168144,-p@chrX:58168137..58168144
-
Hg19::chrX:58169111..58169120,-p@chrX:58169111..58169120
-
Hg19::chrX:58230080..58230084,-p@chrX:58230080..58230084
-
Hg19::chrX:82002721..82002725,-p@chrX:82002721..82002725
-
Hg19::chrX:95277870..95277872,+p@chrX:95277870..95277872
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


p.valueFDRnGenesnPathwayName
1.1538319656142e-077.3037563423379e-05465Endochondral Ossification (Wikipathways):WP474



Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0001501skeletal development1.38622787099341e-05
GO:0001503ossification1.38622787099341e-05
GO:0031214biomineral formation1.38622787099341e-05
GO:0046849bone remodeling1.47690842449678e-05
GO:0048771tissue remodeling1.69478882821983e-05
GO:0009888tissue development0.000973078205899421
GO:0001649osteoblast differentiation0.00331469258547911
GO:0048513organ development0.0109287657732847
GO:0007275multicellular organismal development0.0350956604091168
GO:0032502developmental process0.0372980257525899
GO:0048731system development0.0372980257525899
GO:0004035alkaline phosphatase activity0.0489916179153388



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CD8-positive, alpha-beta T cell1.04e-0711
Uber Anatomy
Ontology termp-valuen
adult organism4.21e-24115
central nervous system3.01e-1182
regional part of nervous system6.14e-1094
nervous system6.14e-1094
brain2.52e-0869
future brain2.52e-0869
neural tube1.05e-0757
neural rod1.05e-0757
future spinal cord1.05e-0757
neural keel1.05e-0757
regional part of brain3.17e-0759
tissue4.96e-07787
blood8.12e-0715
haemolymphatic fluid8.12e-0715
organism substance8.12e-0715


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data