MCL coexpression mm9:301

Phase1 CAGE Peaks

	Short description
Mm9::chr10:77647847..77647900,-	p1@Pwp2
Mm9::chr11:6167721..6167758,-	p1@Ddx56
Mm9::chr11:64792527..64792612,+	p1@Elac2
Mm9::chr11:72254843..72254888,+	p1@Mybbp1a
Mm9::chr13:107737184..107737244,+	p1@Dimt1
Mm9::chr13:3610310..3610364,-	p1@BC016423
Mm9::chr13:54691408..54691450,-	p1@Nop16
Mm9::chr17:24844562..24844606,-	p1@Tbl3
Mm9::chr17:32173344..32173398,+	p1@Rrp1b
Mm9::chr17:47748160..47748193,-	p1@Bysl
Mm9::chr19:41970650..41970697,-	p1@Rrp12
Mm9::chr19:46131044..46131076,+	p1@Pprc1
Mm9::chr1:164478615..164478676,-	p1@Mettl13
Mm9::chr1:9535478..9535560,+	p1@Rrs1
Mm9::chr3:105762371..105762459,+	p1@Wdr77
Mm9::chr3:129534207..129534259,-	p2@Gar1
Mm9::chr4:120242857..120242904,-	p1@Ctps
Mm9::chr4:151413424..151413465,+	p1@Nol9
Mm9::chr4:155610108..155610159,+	p@chr4:155610108..155610159 +
Mm9::chr4:45031491..45031547,+	p1@Polr1e
Mm9::chr5:111082463..111082501,+	p1@Ddx51
Mm9::chr5:120566489..120566534,+	p1@Rbm19
Mm9::chr5:74489137..74489154,+	p1@2700023E23Rik
Mm9::chr6:125081887..125081971,+	p1@Nop2
Mm9::chr7:5013785..5013843,+	p1@U2af2
Mm9::chr7:53086146..53086186,-	p1@Grwd1
Mm9::chr8:90661743..90661801,+	p1@Heatr3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0042254	ribosome biogenesis and assembly	5.11680186249144e-07
GO:0022613	ribonucleoprotein complex biogenesis and assembly	3.20675718272105e-06
GO:0005730	nucleolus	4.9783549932582e-06
GO:0016072	rRNA metabolic process	9.72423441477556e-06
GO:0006364	rRNA processing	9.72423441477556e-06
GO:0005634	nucleus	1.35386557805915e-05
GO:0003723	RNA binding	2.30020001477502e-05
GO:0006396	RNA processing	2.86814449429933e-05
GO:0016070	RNA metabolic process	0.00418132620189929
GO:0043231	intracellular membrane-bound organelle	0.00418132620189929
GO:0043227	membrane-bound organelle	0.00418132620189929
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0057915285466571
GO:0044428	nuclear part	0.0057915285466571
GO:0031981	nuclear lumen	0.00651548456133426
GO:0006996	organelle organization and biogenesis	0.00855697563088129
GO:0031974	membrane-enclosed lumen	0.00855697563088129
GO:0043233	organelle lumen	0.00855697563088129
GO:0010467	gene expression	0.00855697563088129
GO:0031074	nucleocytoplasmic shuttling complex	0.00855697563088129
GO:0042564	NLS-dependent protein nuclear import complex	0.00855697563088129
GO:0001651	dense fibrillar component	0.00855697563088129
GO:0003676	nucleic acid binding	0.00929918789864357
GO:0043229	intracellular organelle	0.0121978450728034
GO:0043226	organelle	0.0121978450728034
GO:0003883	CTP synthase activity	0.0138156121431303
GO:0030515	snoRNA binding	0.0138156121431303
GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.0179509488968946
GO:0016433	rRNA (adenine) methyltransferase activity	0.0179509488968946
GO:0008649	rRNA methyltransferase activity	0.0179509488968946
GO:0008026	ATP-dependent helicase activity	0.0181160658139124
GO:0000154	rRNA modification	0.0224270101912869
GO:0009303	rRNA transcription	0.0271701114396692
GO:0016779	nucleotidyltransferase activity	0.0285973935560174
GO:0004386	helicase activity	0.0388005106397328
GO:0016043	cellular component organization and biogenesis	0.0408817001251616

Relative expression of the co-expression cluster over median <br>Analyst:

---

"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}