MCL coexpression mm9:445

Phase1 CAGE Peaks

	Short description
Mm9::chr13:119521631..119521634,+	p@chr13:119521631..119521634 +
Mm9::chr14:51818615..51818621,-	p@chr14:51818615..51818621 -
Mm9::chr17:14813991..14813999,+	p@chr17:14813991..14813999 +
Mm9::chr2:113589212..113589219,-	p@chr2:113589212..113589219 -
Mm9::chr2:113589255..113589261,-	p@chr2:113589255..113589261 -
Mm9::chr2:113598795..113598812,-	p1@Grem1
Mm9::chr3:141948405..141948408,-	p@chr3:141948405..141948408 -
Mm9::chr3:67308130..67308141,+	p@chr3:67308130..67308141 +
Mm9::chr7:91120932..91120938,-	p@chr7:91120932..91120938 -
Mm9::chr7:91143826..91143830,-	p@chr7:91143826..91143830 -
Mm9::chr7:91196656..91196662,-	p@chr7:91196656..91196662 -
Mm9::chr7:91202832..91202836,-	p@chr7:91202832..91202836 -
Mm9::chr7:91226073..91226075,-	p@chr7:91226073..91226075 -
Mm9::chr8:22042143..22042150,-	p1@Gm15056 p1@LOC100504014
Mm9::chr8:26312911..26312918,-	p@chr8:26312911..26312918 -
Mm9::chr9:96632593..96632620,-	p12@Zbtb38
Mm9::chr9:96632636..96632649,-	p16@Zbtb38

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0009954	proximal/distal pattern formation	0.030231653759293
GO:0030514	negative regulation of BMP signaling pathway	0.030231653759293
GO:0030510	regulation of BMP signaling pathway	0.030231653759293
GO:0001658	ureteric bud branching	0.030231653759293
GO:0030509	BMP signaling pathway	0.030231653759293
GO:0001657	ureteric bud development	0.030231653759293
GO:0001656	metanephros development	0.030231653759293
GO:0048754	branching morphogenesis of a tube	0.030231653759293
GO:0001763	morphogenesis of a branching structure	0.030231653759293
GO:0030326	embryonic limb morphogenesis	0.030231653759293
GO:0035113	embryonic appendage morphogenesis	0.030231653759293
GO:0001822	kidney development	0.030231653759293
GO:0035107	appendage morphogenesis	0.030231653759293
GO:0035108	limb morphogenesis	0.030231653759293
GO:0001655	urogenital system development	0.030231653759293
GO:0048736	appendage development	0.030231653759293
GO:0060173	limb development	0.030231653759293
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	0.030231653759293
GO:0009968	negative regulation of signal transduction	0.0326185805678833
GO:0003002	regionalization	0.0484536275196609
GO:0035239	tube morphogenesis	0.0484536275196609

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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