MCL coexpression mm9:633

Phase1 CAGE Peaks

	Short description
Mm9::chr10:126512385..126512454,+	p@chr10:126512385..126512454 +
Mm9::chr10:20881239..20881254,-	p5@Myb
Mm9::chr10:41788412..41788423,-	p@chr10:41788412..41788423 -
Mm9::chr16:78546887..78546912,-	p@chr16:78546887..78546912 -
Mm9::chr17:28144291..28144354,+	p6@Anks1
Mm9::chr19:46119469..46119478,-	p15@Ldb1
Mm9::chr7:134624130..134624140,+	p@chr7:134624130..134624140 +
Mm9::chr7:82731249..82731262,+	p@chr7:82731249..82731262 +
Mm9::chr7:82731272..82731298,+	p@chr7:82731272..82731298 +
Mm9::chr7:82731305..82731334,+	p@chr7:82731305..82731334 +
Mm9::chr8:75170473..75170495,+	p3@Nwd1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030274	LIM domain binding	0.0269544732372761
GO:0045647	negative regulation of erythrocyte differentiation	0.0319611166067959
GO:0021692	cerebellar Purkinje cell layer morphogenesis	0.0319611166067959
GO:0045646	regulation of erythrocyte differentiation	0.0319611166067959
GO:0021694	cerebellar Purkinje cell layer formation	0.0319611166067959
GO:0021702	cerebellar Purkinje cell differentiation	0.0319611166067959
GO:0021697	cerebellar cortex formation	0.0319611166067959
GO:0021533	cell differentiation in hindbrain	0.0319611166067959
GO:0009948	anterior/posterior axis specification	0.0319611166067959
GO:0021680	cerebellar Purkinje cell layer development	0.0319611166067959
GO:0021696	cerebellar cortex morphogenesis	0.0319611166067959
GO:0021587	cerebellum morphogenesis	0.0319611166067959
GO:0021575	hindbrain morphogenesis	0.0319611166067959
GO:0009798	axis specification	0.0319611166067959
GO:0021695	cerebellar cortex development	0.0319611166067959
GO:0045638	negative regulation of myeloid cell differentiation	0.0319611166067959
GO:0022037	metencephalon development	0.0339834501736818
GO:0021549	cerebellum development	0.0339834501736818
GO:0000082	G1/S transition of mitotic cell cycle	0.0339834501736818
GO:0001702	gastrulation with mouth forming second	0.0416765360980862
GO:0045637	regulation of myeloid cell differentiation	0.0447987456827315
GO:0030218	erythrocyte differentiation	0.0451311553378454
GO:0051325	interphase	0.0451311553378454
GO:0051329	interphase of mitotic cell cycle	0.0451311553378454
GO:0030902	hindbrain development	0.0451311553378454

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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