MCL coexpression mm9:1179

Phase1 CAGE Peaks

	Short description
Mm9::chr1:75176923..75176981,-	p1@Abcb6
Mm9::chr3:120965869..120965887,-	p1@Tmem56
Mm9::chr5:109104613..109104645,-	p3@Slc26a1
Mm9::chr5:109104659..109104671,-	p5@Slc26a1
Mm9::chr5:109104677..109104690,-	p4@Slc26a1
Mm9::chr6:135118149..135118179,-	p1@Hebp1
Mm9::chr6:135118180..135118228,-	p2@Hebp1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0019531	oxalate transmembrane transporter activity	0.00887525338300554
GO:0019532	oxalate transport	0.00887525338300554
GO:0022804	active transmembrane transporter activity	0.0236459546425523
GO:0015116	sulfate transmembrane transporter activity	0.0236459546425523
GO:0008271	secondary active sulfate transmembrane transporter activity	0.0236459546425523
GO:0005310	dicarboxylic acid transmembrane transporter activity	0.0236459546425523
GO:0006835	dicarboxylic acid transport	0.0236459546425523
GO:0015108	chloride transmembrane transporter activity	0.0236459546425523
GO:0008272	sulfate transport	0.0236459546425523
GO:0042168	heme metabolic process	0.0265885828449495
GO:0033013	tetrapyrrole metabolic process	0.0265885828449495
GO:0006778	porphyrin metabolic process	0.0265885828449495
GO:0015103	inorganic anion transmembrane transporter activity	0.0381471072572395
GO:0042440	pigment metabolic process	0.0392078911027292
GO:0019748	secondary metabolic process	0.0481762380020585
GO:0019867	outer membrane	0.0481762380020585
GO:0022857	transmembrane transporter activity	0.0481762380020585
GO:0046943	carboxylic acid transmembrane transporter activity	0.0481762380020585
GO:0005342	organic acid transmembrane transporter activity	0.0481762380020585
GO:0006821	chloride transport	0.0481762380020585
GO:0046942	carboxylic acid transport	0.0481762380020585
GO:0015849	organic acid transport	0.0481762380020585
GO:0005739	mitochondrion	0.0485537446943331
GO:0046483	heterocycle metabolic process	0.0485537446943331

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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