MCL coexpression mm9:1233

Phase1 CAGE Peaks

	Short description
Mm9::chr10:128328919..128328934,-	p2@Gdf11
Mm9::chr8:113245322..113245344,+	p2@Mtss1l
Mm9::chr8:113245351..113245356,+	p5@Mtss1l
Mm9::chr8:113245362..113245386,+	p1@Mtss1l
Mm9::chr8:113245555..113245624,+	p3@Mtss1l
Mm9::chr8:113265086..113265105,+	p@chr8:113265086..113265105 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0031016	pancreas development	0.0179696488248507
GO:0048593	camera-type eye morphogenesis	0.0179696488248507
GO:0001657	ureteric bud development	0.0179696488248507
GO:0048592	eye morphogenesis	0.0179696488248507
GO:0001656	metanephros development	0.0179696488248507
GO:0001822	kidney development	0.0179696488248507
GO:0048469	cell maturation	0.0179696488248507
GO:0043010	camera-type eye development	0.0179696488248507
GO:0001655	urogenital system development	0.0179696488248507
GO:0045596	negative regulation of cell differentiation	0.0179696488248507
GO:0021700	developmental maturation	0.0179696488248507
GO:0001654	eye development	0.0179696488248507
GO:0051093	negative regulation of developmental process	0.0179696488248507
GO:0008285	negative regulation of cell proliferation	0.0189323085833249
GO:0008083	growth factor activity	0.0214793458609544
GO:0045595	regulation of cell differentiation	0.0214793458609544
GO:0007423	sensory organ development	0.0245761373633988
GO:0005125	cytokine activity	0.0267048947813754
GO:0050793	regulation of developmental process	0.0302646717050117
GO:0042127	regulation of cell proliferation	0.0356023667342355
GO:0008283	cell proliferation	0.0494165342683395

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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