MCL coexpression mm9:1689

Phase1 CAGE Peaks

	Short description
Mm9::chr16:17130369..17130373,-	p@chr16:17130369..17130373 -
Mm9::chr16:17132418..17132460,-	p1@Sdf2l1
Mm9::chr6:88034495..88034521,+	p1@Rpn1
Mm9::chr7:107007382..107007416,-	p1@Spcs2
Mm9::chrX:71032542..71032569,+	p2@Ssr4

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005783	endoplasmic reticulum	0.000115134218793879
GO:0005789	endoplasmic reticulum membrane	0.00172589976863339
GO:0042175	nuclear envelope-endoplasmic reticulum network	0.00172589976863339
GO:0044432	endoplasmic reticulum part	0.00172589976863339
GO:0005787	signal peptidase complex	0.00534662679894864
GO:0044444	cytoplasmic part	0.0076367828882567
GO:0006465	signal peptide processing	0.0076367828882567
GO:0012505	endomembrane system	0.00850250242669098
GO:0009003	signal peptidase activity	0.00850250242669098
GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	0.00850250242669098
GO:0004576	oligosaccharyl transferase activity	0.00850250242669098
GO:0006518	peptide metabolic process	0.0100191593261141
GO:0031090	organelle membrane	0.0221189360919881
GO:0005737	cytoplasm	0.0312754297022444

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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