MCL coexpression mm9:3168

Phase1 CAGE Peaks

	Short description
Mm9::chr19:10175991..10176022,-	p1@Fads2
Mm9::chr19:10257396..10257407,+	p4@Fads1
Mm9::chr19:10257411..10257459,+	p1@Fads1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1.12380542994689e-05
GO:0006633	fatty acid biosynthetic process	0.000205094490965306
GO:0046394	carboxylic acid biosynthetic process	0.000205094490965306
GO:0016053	organic acid biosynthetic process	0.000205094490965306
GO:0020037	heme binding	0.000317631118047488
GO:0046906	tetrapyrrole binding	0.000317631118047488
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	0.000345614765162237
GO:0006631	fatty acid metabolic process	0.000496347398226541
GO:0033559	unsaturated fatty acid metabolic process	0.00051797213907552
GO:0006636	unsaturated fatty acid biosynthetic process	0.00051797213907552
GO:0016213	linoleoyl-CoA desaturase activity	0.00051797213907552
GO:0032787	monocarboxylic acid metabolic process	0.00058734442123474
GO:0008610	lipid biosynthetic process	0.000665878730180066
GO:0005506	iron ion binding	0.000960385390342108
GO:0006118	electron transport	0.00102268375246333
GO:0042759	long-chain fatty acid biosynthetic process	0.00142430631939206
GO:0006091	generation of precursor metabolites and energy	0.00153212140282759
GO:0004768	stearoyl-CoA 9-desaturase activity	0.00156283875124613
GO:0019752	carboxylic acid metabolic process	0.00156283875124613
GO:0006082	organic acid metabolic process	0.00156283875124613
GO:0044255	cellular lipid metabolic process	0.00189924604176143
GO:0006629	lipid metabolic process	0.00239902661422411
GO:0005783	endoplasmic reticulum	0.0031149362027669
GO:0001676	long-chain fatty acid metabolic process	0.00332247092140442
GO:0016491	oxidoreductase activity	0.00357302698397313
GO:0044249	cellular biosynthetic process	0.00424092472185725
GO:0009058	biosynthetic process	0.00747993101152702
GO:0006810	transport	0.0278685447113121
GO:0046914	transition metal ion binding	0.0278685447113121
GO:0051234	establishment of localization	0.0279914959145771
GO:0051179	localization	0.0345224871427369
GO:0044444	cytoplasmic part	0.0455975566128692
GO:0043169	cation binding	0.0471255320321226

Relative expression of the co-expression cluster over median <br>Analyst:

---

"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}