MCL coexpression mm9:131
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0030120 | vesicle coat | 0.00591161384004377 |
| GO:0030662 | coated vesicle membrane | 0.00591161384004377 |
| GO:0005798 | Golgi-associated vesicle | 0.00591161384004377 |
| GO:0030659 | cytoplasmic vesicle membrane | 0.00798955422852865 |
| GO:0044433 | cytoplasmic vesicle part | 0.00798955422852865 |
| GO:0030117 | membrane coat | 0.00798955422852865 |
| GO:0048475 | coated membrane | 0.00798955422852865 |
| GO:0012506 | vesicle membrane | 0.00798955422852865 |
| GO:0012505 | endomembrane system | 0.00798955422852865 |
| GO:0015898 | amiloride transport | 0.00798955422852865 |
| GO:0004339 | glucan 1,4-alpha-glucosidase activity | 0.00798955422852865 |
| GO:0030157 | pancreatic juice secretion | 0.00798955422852865 |
| GO:0030135 | coated vesicle | 0.0132705606165686 |
| GO:0048038 | quinone binding | 0.0205344390387834 |
| GO:0004558 | alpha-glucosidase activity | 0.0245938080668312 |
| GO:0044431 | Golgi apparatus part | 0.0245938080668312 |
| GO:0019028 | viral capsid | 0.0252053003267095 |
| GO:0030132 | clathrin coat of coated pit | 0.0252053003267095 |
| GO:0008131 | amine oxidase activity | 0.0252053003267095 |
| GO:0030130 | clathrin coat of trans-Golgi network vesicle | 0.0287057226493634 |
| GO:0016160 | amylase activity | 0.0287057226493634 |
| GO:0008508 | bile acid:sodium symporter activity | 0.0287057226493634 |
| GO:0012510 | trans-Golgi network transport vesicle membrane | 0.0287057226493634 |
| GO:0015125 | bile acid transmembrane transporter activity | 0.0287057226493634 |
| GO:0015926 | glucosidase activity | 0.0287057226493634 |
| GO:0016023 | cytoplasmic membrane-bound vesicle | 0.0287057226493634 |
| GO:0031988 | membrane-bound vesicle | 0.0287057226493634 |
| GO:0051234 | establishment of localization | 0.0287057226493634 |
| GO:0030126 | COPI vesicle coat | 0.0287057226493634 |
| GO:0030663 | COPI coated vesicle membrane | 0.0287057226493634 |
| GO:0008206 | bile acid metabolic process | 0.0292229006652402 |
| GO:0030660 | Golgi-associated vesicle membrane | 0.0292229006652402 |
| GO:0030658 | transport vesicle membrane | 0.0292229006652402 |
| GO:0030137 | COPI-coated vesicle | 0.0292229006652402 |
| GO:0007589 | fluid secretion | 0.0292229006652402 |
| GO:0015711 | organic anion transport | 0.0292229006652402 |
| GO:0030140 | trans-Golgi network transport vesicle | 0.0310102752149507 |
| GO:0030125 | clathrin vesicle coat | 0.0310672223499522 |
| GO:0022600 | digestive system process | 0.0310672223499522 |
| GO:0015893 | drug transport | 0.0310672223499522 |
| GO:0044423 | virion part | 0.0326329409199633 |
| GO:0051179 | localization | 0.033329424528873 |
| GO:0030665 | clathrin coated vesicle membrane | 0.033329424528873 |
| GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | 0.0339629543485862 |
| GO:0008028 | monocarboxylic acid transmembrane transporter activity | 0.0339629543485862 |
| GO:0030133 | transport vesicle | 0.0373592924299797 |
| GO:0005343 | organic acid:sodium symporter activity | 0.0379388381184703 |
| GO:0031410 | cytoplasmic vesicle | 0.0379388381184703 |
| GO:0031982 | vesicle | 0.0381706852158428 |
| GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors | 0.0381706852158428 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
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