MCL coexpression mm9:553

Phase1 CAGE Peaks

	Short description
Mm9::chr10:7552113..7552123,+	p4@Zc3h12d
Mm9::chr10:7552124..7552165,+	p2@Zc3h12d
Mm9::chr10:77761001..77761011,-	p23@Agpat3
Mm9::chr12:102245868..102245883,+	p@chr12:102245868..102245883 +
Mm9::chr14:59879040..59879065,-	p1@Gm6904
Mm9::chr15:97191565..97191586,+	p6@Fam113b
Mm9::chr17:27479398..27479415,+	p1@ENSMUST00000151398 p1@uc012anv.1
Mm9::chr1:165993128..165993139,-	p@chr1:165993128..165993139 -
Mm9::chr3:142159736..142159753,+	p2@Gbp5
Mm9::chr3:142159755..142159768,+	p5@Gbp5
Mm9::chr6:129130657..129130674,+	p2@Clec2d
Mm9::chr6:99255980..99255988,+	p@chr6:99255980..99255988 +
Mm9::chr7:25677212..25677252,-	p@chr7:25677212..25677252 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042270	protection from natural killer cell mediated cytotoxicity	0.0183938166882631
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	0.0183938166882631
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	0.0183938166882631
GO:0045671	negative regulation of osteoclast differentiation	0.0183938166882631
GO:0046703	natural killer cell lectin-like receptor binding	0.0183938166882631
GO:0002762	negative regulation of myeloid leukocyte differentiation	0.0183938166882631
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	0.0183938166882631
GO:0042269	regulation of natural killer cell mediated cytotoxicity	0.0183938166882631
GO:0006955	immune response	0.0183938166882631
GO:0016411	acylglycerol O-acyltransferase activity	0.0183938166882631
GO:0042267	natural killer cell mediated cytotoxicity	0.0183938166882631
GO:0001910	regulation of leukocyte mediated cytotoxicity	0.0183938166882631
GO:0045670	regulation of osteoclast differentiation	0.0183938166882631
GO:0031341	regulation of cell killing	0.0183938166882631
GO:0002228	natural killer cell mediated immunity	0.0183938166882631
GO:0002761	regulation of myeloid leukocyte differentiation	0.0202254373957362
GO:0045638	negative regulation of myeloid cell differentiation	0.0202254373957362
GO:0030316	osteoclast differentiation	0.0202254373957362
GO:0001909	leukocyte mediated cytotoxicity	0.0202254373957362
GO:0001906	cell killing	0.0202254373957362
GO:0002376	immune system process	0.0240773804173256
GO:0008374	O-acyltransferase activity	0.0250618638310431
GO:0045637	regulation of myeloid cell differentiation	0.027959922163863
GO:0002573	myeloid leukocyte differentiation	0.0306143784178908
GO:0008654	phospholipid biosynthetic process	0.0425731710633747

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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