MCL coexpression mm9:727

Phase1 CAGE Peaks

	Short description
Mm9::chr13:74259966..74259982,+	p@chr13:74259966..74259982 +
Mm9::chr14:55028306..55028314,-	p4@Slc7a7
Mm9::chr19:5560202..5560216,+	p@chr19:5560202..5560216 +
Mm9::chr19:8895800..8895821,-	p@chr19:8895800..8895821 -
Mm9::chr4:111571300..111571330,-	p1@Slc5a9
Mm9::chr4:133074636..133074647,+	p6@1810019J16Rik
Mm9::chr8:85982251..85982264,-	p2@LOC100505320 p2@Scoc
Mm9::chr8:85982285..85982296,-	p6@LOC100505320 p6@Scoc
Mm9::chr8:85982305..85982316,-	p9@LOC100505320 p9@Scoc
Mm9::chr8:85982334..85982341,-	p10@LOC100505320 p10@Scoc

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0015174	basic amino acid transmembrane transporter activity	0.0197211644223515
GO:0005275	amine transmembrane transporter activity	0.0328181802038575
GO:0015171	amino acid transmembrane transporter activity	0.0328181802038575
GO:0006865	amino acid transport	0.0328181802038575
GO:0015837	amine transport	0.0328181802038575
GO:0046943	carboxylic acid transmembrane transporter activity	0.0328181802038575
GO:0005342	organic acid transmembrane transporter activity	0.0328181802038575
GO:0046942	carboxylic acid transport	0.0328181802038575
GO:0015849	organic acid transport	0.0328181802038575

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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