MCL coexpression mm9:1121

Phase1 CAGE Peaks

	Short description
Mm9::chr13:73741455..73741568,+	p1@Clptm1l
Mm9::chr2:152495198..152495275,+	p1@H13
Mm9::chr2:157105014..157105053,+	p1@Rpn2
Mm9::chr3:89050319..89050415,+	p1@Krtcap2
Mm9::chr9:103104386..103104440,-	p1@Srprb
Mm9::chr9:44134887..44134979,+	p1@Dpagt1
Mm9::chrX:71032472..71032537,+	p1@Ssr4

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005789	endoplasmic reticulum membrane	2.80521178409458e-07
GO:0042175	nuclear envelope-endoplasmic reticulum network	2.80521178409458e-07
GO:0044432	endoplasmic reticulum part	2.80521178409458e-07
GO:0005783	endoplasmic reticulum	3.09357929991634e-07
GO:0006487	protein amino acid N-linked glycosylation	3.99204309759821e-07
GO:0008250	oligosaccharyl transferase complex	8.94755283546787e-06
GO:0018279	protein amino acid N-linked glycosylation via asparagine	1.11823982613934e-05
GO:0018196	peptidyl-asparagine modification	1.11823982613934e-05
GO:0012505	endomembrane system	1.47309661834202e-05
GO:0006486	protein amino acid glycosylation	1.47309661834202e-05
GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	1.47309661834202e-05
GO:0004576	oligosaccharyl transferase activity	1.47309661834202e-05
GO:0043413	biopolymer glycosylation	1.47309661834202e-05
GO:0009101	glycoprotein biosynthetic process	1.64682503449181e-05
GO:0009100	glycoprotein metabolic process	2.4478207657477e-05
GO:0031090	organelle membrane	9.58941207894332e-05
GO:0016757	transferase activity, transferring glycosyl groups	0.000285339956879038
GO:0044444	cytoplasmic part	0.000520863475800763
GO:0016021	integral to membrane	0.000984579554309227
GO:0031224	intrinsic to membrane	0.000984579554309227
GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	0.00123765458231026
GO:0003975	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity	0.00123765458231026
GO:0044425	membrane part	0.00150615228885894
GO:0018193	peptidyl-amino acid modification	0.00156916233388794
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	0.00217791403198228
GO:0016758	transferase activity, transferring hexosyl groups	0.00303903090771206
GO:0009059	macromolecule biosynthetic process	0.00355282597119315
GO:0016020	membrane	0.00413066954489966
GO:0005737	cytoplasm	0.00781728278606884
GO:0044446	intracellular organelle part	0.0144270990049894
GO:0044422	organelle part	0.0144270990049894
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	0.0144270990049894
GO:0004190	aspartic-type endopeptidase activity	0.0146093576285652
GO:0009058	biosynthetic process	0.0146093576285652
GO:0043231	intracellular membrane-bound organelle	0.015172965163001
GO:0043227	membrane-bound organelle	0.015172965163001
GO:0006464	protein modification process	0.0255950130824752
GO:0043412	biopolymer modification	0.0271795077203998
GO:0043229	intracellular organelle	0.0271795077203998
GO:0043226	organelle	0.0271795077203998
GO:0016740	transferase activity	0.0381109918216993

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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