MCL coexpression mm9:334

Phase1 CAGE Peaks

	Short description
Mm9::chr11:44456621..44456634,+	p@chr11:44456621..44456634 +
Mm9::chr11:44456648..44456656,+	p@chr11:44456648..44456656 +
Mm9::chr12:107682982..107682991,-	p@chr12:107682982..107682991 -
Mm9::chr13:98010402..98010420,+	p@chr13:98010402..98010420 +
Mm9::chr13:98013895..98013931,+	p@chr13:98013895..98013931 +
Mm9::chr13:98014013..98014020,+	p@chr13:98014013..98014020 +
Mm9::chr17:43295228..43295255,-	p1@E130008D07Rik
Mm9::chr17:85116028..85116057,-	p@chr17:85116028..85116057 -
Mm9::chr18:67292732..67292740,+	p@chr18:67292732..67292740 +
Mm9::chr18:67292751..67292763,+	p@chr18:67292751..67292763 +
Mm9::chr1:178744297..178744320,-	p3@Cep170
Mm9::chr2:116223084..116223093,-	p@chr2:116223084..116223093 -
Mm9::chr2:32178964..32178975,-	p@chr2:32178964..32178975 -
Mm9::chr2:69933028..69933041,+	p@chr2:69933028..69933041 +
Mm9::chr3:153991607..153991627,-	p2@Lhx8
Mm9::chr3:153993295..153993298,-	p3@Lhx8
Mm9::chr4:131377546..131377578,-	p3@Ptpru
Mm9::chr4:154597342..154597358,-	p@chr4:154597342..154597358 -
Mm9::chr6:128363704..128363746,-	p@chr6:128363704..128363746 -
Mm9::chr6:99154456..99154464,-	p@chr6:99154456..99154464 -
Mm9::chr6:99154482..99154491,-	p@chr6:99154482..99154491 -
Mm9::chr9:121905215..121905233,+	p@chr9:121905215..121905233 +
Mm9::chr9:53783897..53783904,-	p@chr9:53783897..53783904 -
Mm9::chr9:53783907..53783912,-	p@chr9:53783907..53783912 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0019198	transmembrane receptor protein phosphatase activity	0.0185175039719498
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	0.0185175039719498
GO:0021879	forebrain neuron differentiation	0.0475499523893807
GO:0007191	dopamine receptor, adenylate cyclase activating pathway	0.0475499523893807
GO:0004727	prenylated protein tyrosine phosphatase activity	0.0475499523893807
GO:0021872	generation of neurons in the forebrain	0.0475499523893807
GO:0007190	adenylate cyclase activation	0.0475499523893807
GO:0045762	positive regulation of adenylate cyclase activity	0.0475499523893807
GO:0031281	positive regulation of cyclase activity	0.0475499523893807
GO:0051349	positive regulation of lyase activity	0.0475499523893807
GO:0045761	regulation of adenylate cyclase activity	0.0475499523893807
GO:0031279	regulation of cyclase activity	0.0475499523893807
GO:0007212	dopamine receptor signaling pathway	0.0475499523893807
GO:0051339	regulation of lyase activity	0.0475499523893807
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	0.0493029557375933

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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