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MCL coexpression mm9:1016

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:128328730..128328771,-p1@Gdf11
Mm9::chr11:102680428..102680528,-p1@Gjc1
Mm9::chr14:52604501..52604531,+p2@Arhgef40
Mm9::chr17:28314586..28314627,-p@chr17:28314586..28314627
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Mm9::chr2:58419568..58419699,-p1@Acvr1
Mm9::chr9:56842884..56842924,+p2@Ptpn9
Mm9::chrX:147481455..147481476,+p2@Fgd1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0009653anatomical structure morphogenesis0.00296909382281702
GO:0009887organ morphogenesis0.00646380487127128
GO:0001655urogenital system development0.00646380487127128
GO:0048856anatomical structure development0.00646380487127128
GO:0050431transforming growth factor beta binding0.00959842217717636
GO:0016361activin receptor activity, type I0.0121739696266195
GO:0017002activin receptor activity0.0121739696266195
GO:0007507heart development0.0121739696266195
GO:0048514blood vessel morphogenesis0.0121739696266195
GO:0032502developmental process0.0121739696266195
GO:0005025transforming growth factor beta receptor activity, type I0.0126221882574342
GO:0001568blood vessel development0.0126221882574342
GO:0001944vasculature development0.0126221882574342
GO:0048468cell development0.0127947411668825
GO:0060037pharyngeal system development0.0127947411668825
GO:0050793regulation of developmental process0.0157949769515772
GO:0048185activin binding0.0169314328740094
GO:0048513organ development0.017489293322562
GO:0051145smooth muscle cell differentiation0.0215822546795309
GO:0048738cardiac muscle development0.0215822546795309
GO:0004675transmembrane receptor protein serine/threonine kinase activity0.0239763413012367
GO:0005024transforming growth factor beta receptor activity0.0239763413012367
GO:0048731system development0.0242921967687915
GO:0031016pancreas development0.0242921967687915
GO:0048869cellular developmental process0.0242921967687915
GO:0030154cell differentiation0.0242921967687915
GO:0048593camera-type eye morphogenesis0.0287550599656491
GO:0022829wide pore channel activity0.0287550599656491
GO:0005243gap junction channel activity0.0287550599656491
GO:0005922connexon complex0.0287550599656491
GO:0001569patterning of blood vessels0.0340001801508854
GO:0001755neural crest cell migration0.0340268617337679
GO:0001707mesoderm formation0.0340268617337679
GO:0048332mesoderm morphogenesis0.0340268617337679
GO:0005921gap junction0.0340268617337679
GO:0007275multicellular organismal development0.0340268617337679
GO:0001704formation of primary germ layer0.0340268617337679
GO:0007281germ cell development0.0340268617337679
GO:0001570vasculogenesis0.0356044036869571
GO:0001702gastrulation with mouth forming second0.0356241688914495
GO:0014032neural crest cell development0.0356241688914495
GO:0014033neural crest cell differentiation0.0356241688914495
GO:0001657ureteric bud development0.0356241688914495
GO:0007368determination of left/right symmetry0.0356390644170355
GO:0001726ruffle0.0356390644170355
GO:0009799determination of symmetry0.0356390644170355
GO:0009855determination of bilateral symmetry0.0356390644170355
GO:0048762mesenchymal cell differentiation0.0380786740322516
GO:0014031mesenchymal cell development0.0380786740322516
GO:0009880embryonic pattern specification0.0382708027366175
GO:0048592eye morphogenesis0.0383992257020482
GO:0014704intercalated disc0.0383992257020482
GO:0001656metanephros development0.0383992257020482
GO:0007179transforming growth factor beta receptor signaling pathway0.0383992257020482
GO:0004702receptor signaling protein serine/threonine kinase activity0.0383992257020482
GO:0022603regulation of anatomical structure morphogenesis0.0383992257020482
GO:0022604regulation of cell morphogenesis0.0383992257020482
GO:0008360regulation of cell shape0.0383992257020482
GO:0019838growth factor binding0.0383992257020482
GO:0007498mesoderm development0.0383992257020482
GO:0030027lamellipodium0.0383992257020482
GO:0005089Rho guanyl-nucleotide exchange factor activity0.040850517821372
GO:0035023regulation of Rho protein signal transduction0.042467210308323
GO:0048754branching morphogenesis of a tube0.0432895282359754
GO:0005088Ras guanyl-nucleotide exchange factor activity0.043354858875854
GO:0007369gastrulation0.0442372284256234
GO:0001763morphogenesis of a branching structure0.0442372284256234
GO:0042692muscle cell differentiation0.0442372284256234
GO:0019955cytokine binding0.0463488678699826
GO:0001822kidney development0.047693177764072
GO:0019199transmembrane receptor protein kinase activity0.047693177764072
GO:0048469cell maturation0.047693177764072
GO:0048729tissue morphogenesis0.047693177764072
GO:0043010camera-type eye development0.047693177764072
GO:0031252leading edge0.047693177764072
GO:0002526acute inflammatory response0.047693177764072
GO:0045177apical part of cell0.047693177764072
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway0.0482849740211149
GO:0007266Rho protein signal transduction0.0482849740211149



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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