MCL coexpression mm9:1043

Phase1 CAGE Peaks

	Short description
Mm9::chr10:80261375..80261387,+	p2@Sf3a2
Mm9::chr13:74075209..74075235,-	p3@Trip13
Mm9::chr17:25864309..25864371,-	p1@Chtf18
Mm9::chr17:35118843..35118885,+	p2@Lsm2
Mm9::chr17:56179847..56179868,+	p2@Chaf1a
Mm9::chr19:6085039..6085051,+	p2@Cdca5
Mm9::chr4:124614077..124614088,-	p2@Cdca8

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0000375	RNA splicing, via transesterification reactions	0.00366088563816577
GO:0000398	nuclear mRNA splicing, via spliceosome	0.00366088563816577
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	0.00366088563816577
GO:0000351	assembly of spliceosomal tri-snRNP U4/U6.U5	0.0157720689898799
GO:0006374	nuclear mRNA splicing via U2-type spliceosome	0.0157720689898799
GO:0000387	spliceosomal snRNP biogenesis	0.0157720689898799
GO:0000244	assembly of spliceosomal tri-snRNP	0.0157720689898799
GO:0005681	spliceosome	0.0157720689898799
GO:0007067	mitosis	0.0157720689898799
GO:0007049	cell cycle	0.0157720689898799
GO:0000087	M phase of mitotic cell cycle	0.0157720689898799
GO:0008380	RNA splicing	0.0157720689898799
GO:0046540	U4/U6 x U5 tri-snRNP complex	0.0157720689898799
GO:0000278	mitotic cell cycle	0.0207318967750936
GO:0006397	mRNA processing	0.0207318967750936
GO:0000279	M phase	0.0207318967750936
GO:0051301	cell division	0.0207318967750936
GO:0016071	mRNA metabolic process	0.0229934679448512
GO:0030532	small nuclear ribonucleoprotein complex	0.023320273436187
GO:0022403	cell cycle phase	0.023320273436187
GO:0031202	RNA splicing factor activity, transesterification mechanism	0.023405844151925
GO:0005634	nucleus	0.0319252401371916
GO:0006396	RNA processing	0.0330509239918394
GO:0006402	mRNA catabolic process	0.0476614567240531
GO:0030529	ribonucleoprotein complex	0.0487217682126219

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}