MCL coexpression mm9:1311

Phase1 CAGE Peaks

	Short description
Mm9::chr11:94798896..94798917,+	p2@Col1a1
Mm9::chr1:92740493..92740560,-	p1@Col6a3
Mm9::chr2:27741525..27741567,+	p5@Col5a1
Mm9::chr3:89019114..89019165,+	p1@Thbs3
Mm9::chr4:129725100..129725145,+	p1@Col16a1
Mm9::chr4:129725158..129725173,+	p2@Col16a1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0030020	extracellular matrix structural constituent conferring tensile strength	8.72311481393277e-10
GO:0005581	collagen	9.61269049277178e-10
GO:0005201	extracellular matrix structural constituent	5.96172661944039e-09
GO:0044420	extracellular matrix part	2.558454986592e-08
GO:0022610	biological adhesion	1.93364214938847e-07
GO:0007155	cell adhesion	1.93364214938847e-07
GO:0005578	proteinaceous extracellular matrix	1.28211520733708e-06
GO:0006817	phosphate transport	1.99849138100649e-06
GO:0015698	inorganic anion transport	1.64977104979795e-05
GO:0006820	anion transport	2.47825890742026e-05
GO:0044421	extracellular region part	6.02870362699742e-05
GO:0006811	ion transport	0.00145169204086382
GO:0005615	extracellular space	0.00161700268652046
GO:0005588	collagen type V	0.00199532068133874
GO:0005583	fibrillar collagen	0.00248279364980585
GO:0006810	transport	0.0301890670517649
GO:0008201	heparin binding	0.0301890670517649
GO:0051234	establishment of localization	0.0301890670517649
GO:0005604	basement membrane	0.0301890670517649
GO:0005539	glycosaminoglycan binding	0.034185523575404
GO:0030247	polysaccharide binding	0.034782120041712
GO:0001871	pattern binding	0.034782120041712
GO:0051179	localization	0.034782120041712

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}