MCL coexpression mm9:1900

Phase1 CAGE Peaks

	Short description
Mm9::chr10:61595830..61595846,+	p1@Neurog3
Mm9::chr14:21088395..21088466,-	p1@Kcnk16
Mm9::chr5:102094266..102094273,-	p3@Nkx6-1
Mm9::chr7:53378279..53378296,-	p@chr7:53378279..53378296 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0014015	positive regulation of gliogenesis	0.0204886258835343
GO:0045687	positive regulation of glial cell differentiation	0.0204886258835343
GO:0014014	negative regulation of gliogenesis	0.0204886258835343
GO:0045686	negative regulation of glial cell differentiation	0.0204886258835343
GO:0031018	endocrine pancreas development	0.0204886258835343
GO:0045685	regulation of glial cell differentiation	0.0204886258835343
GO:0014013	regulation of gliogenesis	0.0204886258835343
GO:0031016	pancreas development	0.0258896710143042
GO:0007399	nervous system development	0.0361739308667917
GO:0048522	positive regulation of cellular process	0.0431850663942103
GO:0003700	transcription factor activity	0.0431850663942103
GO:0030855	epithelial cell differentiation	0.0431850663942103
GO:0048518	positive regulation of biological process	0.0431850663942103
GO:0010001	glial cell differentiation	0.0431850663942103
GO:0042063	gliogenesis	0.0434809669749313
GO:0045597	positive regulation of cell differentiation	0.0448985397294573
GO:0035270	endocrine system development	0.0448985397294573

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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