MCL coexpression mm9:1326

Phase1 CAGE Peaks

	Short description
Mm9::chr12:55757483..55757504,-	p1@1110002B05Rik
Mm9::chr5:104450798..104450815,-	p2@Hsd17b11
Mm9::chr5:104450818..104450884,-	p1@Hsd17b11
Mm9::chr5:8996618..8996632,-	p2@Crot
Mm9::chr5:8996642..8996647,-	p9@Crot
Mm9::chr5:8996655..8996667,-	p5@Crot

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008458	carnitine O-octanoyltransferase activity	0.0025749191913658
GO:0016415	octanoyltransferase activity	0.0025749191913658
GO:0016414	O-octanoyltransferase activity	0.0025749191913658
GO:0015908	fatty acid transport	0.00926716990639254
GO:0016406	carnitine O-acyltransferase activity	0.00926716990639254
GO:0004303	estradiol 17-beta-dehydrogenase activity	0.0102957270702699
GO:0044255	cellular lipid metabolic process	0.0151652090407481
GO:0006629	lipid metabolic process	0.0175099004677222
GO:0016229	steroid dehydrogenase activity	0.0180046905529867
GO:0008374	O-acyltransferase activity	0.0231374707154451
GO:0006694	steroid biosynthetic process	0.0474457324366066
GO:0006869	lipid transport	0.0474457324366066
GO:0042579	microbody	0.0483245373075855
GO:0005777	peroxisome	0.0483245373075855

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
epithelial cell	6.09e-08	25

Uber Anatomy

Ontology term	p-value	n
intestine	1.27e-15	31
gastrointestinal system	1.85e-13	47
endoderm-derived structure	2.17e-13	118
endoderm	2.17e-13	118
presumptive endoderm	2.17e-13	118
digestive system	8.63e-13	116
digestive tract	8.63e-13	116
primitive gut	8.63e-13	116
subdivision of digestive tract	6.77e-12	114
mucosa	1.82e-09	15
intestinal mucosa	2.01e-08	13
anatomical wall	2.01e-08	13
wall of intestine	2.01e-08	13
gastrointestinal system mucosa	2.01e-08	13
trunk mesenchyme	6.03e-07	45

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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