MCL coexpression mm9:1328

Phase1 CAGE Peaks

	Short description
Mm9::chr12:71328609..71328626,-	p1@Pygl
Mm9::chr1:183187792..183187805,-	p@chr1:183187792..183187805 -
Mm9::chr6:138088819..138088841,+	p2@Mgst1
Mm9::chr8:36439699..36439722,+	p1@Ppp1r3b
Mm9::chr8:36439734..36439750,+	p3@Ppp1r3b
Mm9::chrX:138662827..138662849,+	p3@Nxt2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0006073	glucan metabolic process	0.00056300435164188
GO:0005977	glycogen metabolic process	0.00056300435164188
GO:0006112	energy reserve metabolic process	0.00056300435164188
GO:0005976	polysaccharide metabolic process	0.000613183580318231
GO:0044264	cellular polysaccharide metabolic process	0.000613183580318231
GO:0015980	energy derivation by oxidation of organic compounds	0.00101252787028551
GO:0008184	glycogen phosphorylase activity	0.0049459428233834
GO:0004645	phosphorylase activity	0.00865397733034007
GO:0044262	cellular carbohydrate metabolic process	0.00951050988939786
GO:0005975	carbohydrate metabolic process	0.0166545253887196
GO:0006091	generation of precursor metabolites and energy	0.0209472227611453
GO:0006749	glutathione metabolic process	0.0259106685090976
GO:0000267	cell fraction	0.0259106685090976
GO:0004364	glutathione transferase activity	0.0283901252252494

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

---

Uber Anatomy

Ontology term	p-value	n
epithelial tube	2.34e-09	47
liver	6.45e-08	22
epithelial sac	6.45e-08	22
digestive gland	6.45e-08	22
epithelium of foregut-midgut junction	6.45e-08	22
anatomical boundary	6.45e-08	22
hepatobiliary system	6.45e-08	22
foregut-midgut junction	6.45e-08	22
hepatic diverticulum	6.45e-08	22
liver primordium	6.45e-08	22
septum transversum	6.45e-08	22
liver bud	6.45e-08	22
subdivision of trunk	9.11e-08	66
exocrine gland	1.74e-07	25
exocrine system	1.74e-07	25
digestive tract diverticulum	1.81e-07	23
sac	1.81e-07	23
trunk mesenchyme	4.14e-07	45

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}