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MCL coexpression mm9:1344

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:4278636..4278655,-p1@Akr1c12
Mm9::chr3:10335409..10335441,-p@chr3:10335409..10335441
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Mm9::chr4:106987004..106987029,+p2@Yipf1
Mm9::chr5:87997915..87997933,-p1@Sult1d1
Mm9::chr5:87997938..87997949,-p5@Sult1d1
Mm9::chr7:26262616..26262621,-p3@Ceacam1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0017067tyrosine-ester sulfotransferase activity0.0180732773037338
GO:0004062aryl sulfotransferase activity0.0180732773037338
GO:0006791sulfur utilization0.0180732773037338
GO:0000103sulfate assimilation0.0180732773037338
GO:0008508bile acid:sodium symporter activity0.0240871425889528
GO:0015125bile acid transmembrane transporter activity0.0240871425889528
GO:0006805xenobiotic metabolic process0.0288792426108508
GO:0009410response to xenobiotic stimulus0.0288792426108508
GO:0004033aldo-keto reductase activity0.0288792426108508
GO:0008028monocarboxylic acid transmembrane transporter activity0.0288792426108508
GO:0005343organic acid:sodium symporter activity0.0311662075486136



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
epithelial cell2.65e-0725

Uber Anatomy
Ontology termp-valuen
intestine2.10e-2031
gastrointestinal system6.91e-2047
endoderm-derived structure4.42e-19118
endoderm4.42e-19118
presumptive endoderm4.42e-19118
digestive system1.28e-18116
digestive tract1.28e-18116
primitive gut1.28e-18116
subdivision of digestive tract2.93e-17114
mucosa3.21e-1115
intestinal mucosa1.17e-0913
anatomical wall1.17e-0913
wall of intestine1.17e-0913
gastrointestinal system mucosa1.17e-0913
digestive tract diverticulum1.37e-0923
sac1.37e-0923
liver8.33e-0922
epithelial sac8.33e-0922
digestive gland8.33e-0922
epithelium of foregut-midgut junction8.33e-0922
anatomical boundary8.33e-0922
hepatobiliary system8.33e-0922
foregut-midgut junction8.33e-0922
hepatic diverticulum8.33e-0922
liver primordium8.33e-0922
septum transversum8.33e-0922
liver bud8.33e-0922
exocrine gland6.23e-0825
exocrine system6.23e-0825
organ component layer1.66e-0724
abdomen element2.29e-0749
abdominal segment element2.29e-0749
abdominal segment of trunk2.29e-0749
abdomen2.29e-0749
trunk region element2.81e-0779
subdivision of trunk3.62e-0766


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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