MCL coexpression mm9:2151

Phase1 CAGE Peaks

	Short description
Mm9::chr15:76036727..76036732,-	p21@Plec
Mm9::chr15:76036739..76036787,-	p3@Plec
Mm9::chr3:88307109..88307245,-	p1@Lmna
Mm9::chr3:88307253..88307272,-	p2@Lmna

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005638	lamin filament	0.00405412808853339
GO:0006998	nuclear membrane organization and biogenesis	0.00405412808853339
GO:0005652	nuclear lamina	0.00405412808853339
GO:0005637	nuclear inner membrane	0.00405412808853339
GO:0006997	nuclear organization and biogenesis	0.0105407330301868
GO:0044453	nuclear membrane part	0.0182435763984003
GO:0031965	nuclear membrane	0.0182435763984003
GO:0005635	nuclear envelope	0.024527474935627
GO:0005882	intermediate filament	0.024527474935627
GO:0045111	intermediate filament cytoskeleton	0.024527474935627
GO:0016044	membrane organization and biogenesis	0.0402034368779562
GO:0019866	organelle inner membrane	0.0402034368779562
GO:0012505	endomembrane system	0.045375048990893

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>

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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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