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MCL coexpression mm9:3696

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Phase1 CAGE Peaks

 Short description
Mm9::chr9:108997764..108997785,+p3@Plxnb1
Mm9::chr9:108998289..108998318,-p@chr9:108998289..108998318
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Mm9::chr9:108998327..108998340,-p@chr9:108998327..108998340
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050772positive regulation of axonogenesis0.0180792198542705
GO:0050769positive regulation of neurogenesis0.0180792198542705
GO:0050770regulation of axonogenesis0.0241056264723607
GO:0050767regulation of neurogenesis0.0271188297814058
GO:0051094positive regulation of developmental process0.0332657645318578
GO:0007409axonogenesis0.0417328658302745
GO:0048667neuron morphogenesis during differentiation0.0417328658302745
GO:0048812neurite morphogenesis0.0417328658302745
GO:0000904cellular morphogenesis during differentiation0.0417328658302745
GO:0031175neurite development0.0417328658302745
GO:0048666neuron development0.0417328658302745
GO:0050793regulation of developmental process0.0417328658302745
GO:0032990cell part morphogenesis0.0417328658302745
GO:0030030cell projection organization and biogenesis0.0417328658302745
GO:0048858cell projection morphogenesis0.0417328658302745
GO:0030182neuron differentiation0.0417328658302745
GO:0048699generation of neurons0.0446663078752566
GO:0022008neurogenesis0.0452650097092107



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuron2.38e-1033
neuronal stem cell2.38e-1033
neuroblast2.38e-1033
electrically signaling cell2.38e-1033
ectodermal cell4.32e-0944
neurectodermal cell4.32e-0944
neural cell8.14e-0943
electrically responsive cell3.75e-0739
electrically active cell3.75e-0739
autonomic neuron7.61e-079


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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