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MCL coexpression mm9:1626

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:73862204..73862252,+p2@Ppm1a
Mm9::chr12:73862254..73862303,+p1@Ppm1a
Mm9::chr15:31460754..31460824,-p1@March6
Mm9::chr16:13671951..13672011,+p2@3110001I22Rik
p2@Bfar
Mm9::chr5:89315834..89315850,+p1@Slc4a4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008510sodium:bicarbonate symporter activity0.0149564455158056
GO:0015701bicarbonate transport0.0256241713817642
GO:0005452inorganic anion exchanger activity0.0256241713817642
GO:0015380anion exchanger activity0.0256241713817642
GO:0015106bicarbonate transmembrane transporter activity0.0256241713817642
GO:0015301anion:anion antiporter activity0.0256241713817642
GO:0015108chloride transmembrane transporter activity0.0256241713817642
GO:0015296anion:cation symporter activity0.0283892302834395
GO:0006885regulation of pH0.0283892302834395
GO:0015071protein phosphatase type 2C activity0.0283892302834395
GO:0008287protein serine/threonine phosphatase complex0.0285219372589867
GO:0015103inorganic anion transmembrane transporter activity0.0336041502350863
GO:0004722protein serine/threonine phosphatase activity0.0336041502350863
GO:0043169cation binding0.0336041502350863
GO:0015297antiporter activity0.0376142207968676
GO:0046872metal ion binding0.0376142207968676
GO:0043167ion binding0.0376485239032373
GO:0015294solute:cation symporter activity0.0430868884768256



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
anatomical conduit1.56e-09122
regional part of nervous system1.71e-0954
tube3.34e-09114
neural tube2.42e-0852
neural rod2.42e-0852
future spinal cord2.42e-0852
neural keel2.42e-0852
multi-tissue structure2.75e-08230
gray matter1.35e-0734
occipital lobe5.40e-0710
visual cortex5.40e-0710
neocortex5.40e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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