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MCL coexpression mm9:2944

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Phase1 CAGE Peaks

 Short description
Mm9::chr14:79029093..79029099,-p1@Dgkh
Mm9::chr2:79548073..79548084,+p1@Ppp1r1c
Mm9::chrX:56419257..56419278,-p8@Fgf13


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0046339diacylglycerol metabolic process0.0200568719306714
GO:0030295protein kinase activator activity0.0200568719306714
GO:0019209kinase activator activity0.0200568719306714
GO:0004143diacylglycerol kinase activity0.0200568719306714
GO:0004864protein phosphatase inhibitor activity0.0200568719306714
GO:0019212phosphatase inhibitor activity0.0200568719306714
GO:0006639acylglycerol metabolic process0.0200568719306714
GO:0006638neutral lipid metabolic process0.0200568719306714
GO:0046486glycerolipid metabolic process0.0200568719306714
GO:0006662glycerol ether metabolic process0.0200568719306714
GO:0019888protein phosphatase regulator activity0.0224338754751459
GO:0019208phosphatase regulator activity0.0224885981094761
GO:0019887protein kinase regulator activity0.0373083415627579
GO:0019207kinase regulator activity0.0406677706599485



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
pituitary gland4.03e-078
gland of diencephalon4.03e-078
neuroendocrine gland4.03e-078
spinal cord9.03e-076
dorsal region element9.03e-076
dorsum9.03e-076


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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