Novel motif:67

name:	motif67_GNTAAC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0002544	chronic inflammatory response	1.282735e-9
GO:0016476	regulation of embryonic cell shape	4.722616e-9
GO:0010038	response to metal ion	5.372973e-8
GO:0071842	cellular component organization at cellular level	1.579434e-7
GO:0016043	cellular component organization	2.020590e-7
GO:0071841	cellular component organization or biogenesis at cellular level	3.823374e-7
GO:0071840	cellular component organization or biogenesis	4.849073e-7
GO:0042221	response to chemical stimulus	5.144895e-7
GO:0051276	chromosome organization	5.505559e-7
GO:0051258	protein polymerization	6.227989e-7
GO:0042135	neurotransmitter catabolic process	9.309803e-7
GO:0006104	succinyl-CoA metabolic process	9.720722e-7
GO:0031129	inductive cell-cell signaling	1.523825e-6
GO:0070827	chromatin maintenance	1.906622e-6
GO:0035945	mitochondrial ncRNA surveillance	1.906622e-6
GO:0035946	mitochondrial mRNA surveillance	1.906622e-6
GO:0010033	response to organic substance	2.570744e-6
GO:0030299	intestinal cholesterol absorption	2.779431e-6
GO:0048619	embryonic hindgut morphogenesis	3.635822e-6
GO:0006996	organelle organization	3.636359e-6
GO:0009068	aspartate family amino acid catabolic process	6.485813e-6
GO:0009220	pyrimidine ribonucleotide biosynthetic process	6.515816e-6
GO:0032514	positive regulation of protein phosphatase type 2B activity	7.011167e-6
GO:0045666	positive regulation of neuron differentiation	8.284885e-6
GO:0007049	cell cycle	8.541846e-6
GO:0051592	response to calcium ion	9.504806e-6
GO:0030030	cell projection organization	9.919263e-6
GO:0009218	pyrimidine ribonucleotide metabolic process	1.105528e-5
GO:0008152	metabolic process	1.116634e-5
GO:0034622	cellular macromolecular complex assembly	1.218671e-5
GO:0050916	sensory perception of sweet taste	1.410697e-5
GO:0002526	acute inflammatory response	1.468294e-5
GO:2000009	negative regulation of protein localization at cell surface	1.613001e-5
GO:0032512	regulation of protein phosphatase type 2B activity	1.693436e-5
GO:0009066	aspartate family amino acid metabolic process	1.701412e-5
GO:0015949	nucleobase-containing small molecule interconversion	1.816743e-5
GO:0044237	cellular metabolic process	1.819137e-5
GO:0043030	regulation of macrophage activation	1.944270e-5
GO:0032990	cell part morphogenesis	1.976522e-5
GO:0043623	cellular protein complex assembly	2.097520e-5
GO:0006325	chromatin organization	2.121677e-5
GO:0034621	cellular macromolecular complex subunit organization	2.285155e-5
GO:0010940	positive regulation of necrotic cell death	2.362316e-5
GO:0048858	cell projection morphogenesis	2.712751e-5
GO:0033120	positive regulation of RNA splicing	2.732446e-5
GO:0009310	amine catabolic process	2.771594e-5
GO:0043503	skeletal muscle fiber adaptation	2.784372e-5
GO:0032026	response to magnesium ion	2.860017e-5
GO:0042060	wound healing	3.183477e-5
GO:0009611	response to wounding	3.212022e-5
GO:0008219	cell death	3.214837e-5
GO:0008228	opsonization	3.348431e-5
GO:0006950	response to stress	3.616525e-5
GO:0006781	succinyl-CoA pathway	3.665679e-5
GO:0034197	triglyceride transport	3.820043e-5
GO:0016265	death	4.000798e-5
GO:0032890	regulation of organic acid transport	4.066739e-5
GO:0051642	centrosome localization	4.227173e-5
GO:0007599	hemostasis	4.278972e-5
GO:0030240	skeletal muscle thin filament assembly	4.500252e-5
GO:0044238	primary metabolic process	4.546309e-5
GO:0070106	interleukin-27-mediated signaling pathway	4.721244e-5
GO:0048015	phosphatidylinositol-mediated signaling	4.907864e-5
GO:0060004	reflex	4.997249e-5
GO:0032989	cellular component morphogenesis	5.141812e-5
GO:0034763	negative regulation of transmembrane transport	5.171433e-5
GO:0007596	blood coagulation	5.367799e-5
GO:0032891	negative regulation of organic acid transport	5.384393e-5
GO:0002023	reduction of food intake in response to dietary excess	5.604380e-5
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	6.482148e-5
GO:0006542	glutamine biosynthetic process	6.554453e-5
GO:0048662	negative regulation of smooth muscle cell proliferation	6.648035e-5
GO:0050896	response to stimulus	7.053772e-5
GO:0002439	chronic inflammatory response to antigenic stimulus	7.860020e-5
GO:0061034	olfactory bulb mitral cell layer development	7.967039e-5
GO:0051320	S phase	8.790155e-5
GO:0043933	macromolecular complex subunit organization	9.085375e-5
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	9.382639e-5
GO:0070562	regulation of vitamin D receptor signaling pathway	9.382639e-5
GO:0071353	cellular response to interleukin-4	9.390799e-5
GO:0000902	cell morphogenesis	9.625175e-5
GO:0090274	positive regulation of somatostatin secretion	9.770811e-5
GO:0045023	G0 to G1 transition	9.770811e-5
GO:0031334	positive regulation of protein complex assembly	1.082716e-4
GO:0060556	regulation of vitamin D biosynthetic process	1.103313e-4
GO:0044241	lipid digestion	1.154279e-4
GO:0045214	sarcomere organization	1.155191e-4
GO:0035871	protein K11-linked deubiquitination	1.194373e-4
GO:0060005	vestibular reflex	1.199409e-4
GO:0010288	response to lead ion	1.206008e-4
GO:0009987	cellular process	1.230960e-4
GO:0030538	embryonic genitalia morphogenesis	1.231644e-4
GO:0055096	low-density lipoprotein particle mediated signaling	1.266311e-4
GO:0071526	semaphorin-plexin signaling pathway	1.281511e-4
GO:0060557	positive regulation of vitamin D biosynthetic process	1.291769e-4
GO:0030827	negative regulation of cGMP biosynthetic process	1.356060e-4
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	1.452117e-4
GO:0006467	protein thiol-disulfide exchange	1.452117e-4
GO:0042420	dopamine catabolic process	1.463128e-4
GO:0010939	regulation of necrotic cell death	1.533383e-4
GO:0022402	cell cycle process	1.534232e-4
GO:0010722	regulation of ferrochelatase activity	1.580252e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	1.667998e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	1.667998e-4
GO:0012501	programmed cell death	1.690512e-4
GO:0006241	CTP biosynthetic process	1.694788e-4
GO:0010883	regulation of lipid storage	1.876410e-4
GO:0060191	regulation of lipase activity	1.924684e-4
GO:0051533	positive regulation of NFAT protein import into nucleus	2.036753e-4
GO:2000659	regulation of interleukin-1-mediated signaling pathway	2.040100e-4
GO:0030534	adult behavior	2.087869e-4
GO:0050878	regulation of body fluid levels	2.132447e-4
GO:0010922	positive regulation of phosphatase activity	2.157113e-4
GO:0007442	hindgut morphogenesis	2.280374e-4
GO:0006554	lysine catabolic process	2.282276e-4
GO:0072093	metanephric renal vesicle formation	2.306329e-4
GO:0048263	determination of dorsal identity	2.330099e-4
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway	2.330099e-4
GO:2000191	regulation of fatty acid transport	2.364715e-4
GO:0061048	negative regulation of branching involved in lung morphogenesis	2.445148e-4
GO:0000084	S phase of mitotic cell cycle	2.501207e-4
GO:0034391	regulation of smooth muscle cell apoptosis	2.527017e-4
GO:0030321	transepithelial chloride transport	2.535580e-4
GO:0006927	transformed cell apoptosis	2.535580e-4
GO:0001778	plasma membrane repair	2.591738e-4
GO:0031123	RNA 3'-end processing	2.817705e-4
GO:0019932	second-messenger-mediated signaling	2.978393e-4
GO:0043277	apoptotic cell clearance	3.161597e-4
GO:0023057	negative regulation of signaling	3.396401e-4
GO:0046683	response to organophosphorus	3.415809e-4
GO:0010648	negative regulation of cell communication	3.505903e-4
GO:0065003	macromolecular complex assembly	3.519717e-4
GO:0031175	neuron projection development	3.668623e-4
GO:0050917	sensory perception of umami taste	3.771102e-4
GO:0009968	negative regulation of signal transduction	3.790519e-4
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	3.801316e-4
GO:0033345	asparagine catabolic process via L-aspartate	3.801316e-4
GO:0034115	negative regulation of heterotypic cell-cell adhesion	3.991145e-4
GO:0042424	catecholamine catabolic process	4.040639e-4
GO:0048666	neuron development	4.079709e-4
GO:0016568	chromatin modification	4.142878e-4
GO:0009895	negative regulation of catabolic process	4.327789e-4
GO:0006925	inflammatory cell apoptosis	4.501979e-4
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	4.651130e-4
GO:0035456	response to interferon-beta	4.700634e-4
GO:0050892	intestinal absorption	4.904765e-4
GO:0043032	positive regulation of macrophage activation	4.945382e-4
GO:0006119	oxidative phosphorylation	5.090038e-4
GO:0016570	histone modification	5.148892e-4
GO:0018283	iron incorporation into metallo-sulfur cluster	5.214031e-4
GO:0006221	pyrimidine nucleotide biosynthetic process	5.215757e-4
GO:0048585	negative regulation of response to stimulus	5.238277e-4
GO:0006915	apoptosis	5.426062e-4
GO:0071822	protein complex subunit organization	5.654041e-4
GO:0050885	neuromuscular process controlling balance	5.814385e-4
GO:0051726	regulation of cell cycle	5.986306e-4
GO:0006214	thymidine catabolic process	6.001672e-4
GO:0072092	ureteric bud invasion	6.041445e-4
GO:0006464	protein modification process	6.101213e-4
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	6.234845e-4
GO:0031124	mRNA 3'-end processing	6.621419e-4
GO:0001937	negative regulation of endothelial cell proliferation	6.657713e-4
GO:0071803	positive regulation of podosome assembly	6.880854e-4
GO:0010390	histone monoubiquitination	7.041688e-4
GO:0042133	neurotransmitter metabolic process	7.059670e-4
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	7.285786e-4
GO:0046685	response to arsenic-containing substance	7.305135e-4
GO:0048812	neuron projection morphogenesis	7.345793e-4
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	7.368994e-4
GO:0043067	regulation of programmed cell death	7.416979e-4
GO:0010921	regulation of phosphatase activity	7.440115e-4
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	7.610337e-4
GO:0060662	salivary gland cavitation	7.653842e-4
GO:0080135	regulation of cellular response to stress	7.723956e-4
GO:0060008	Sertoli cell differentiation	8.014189e-4
GO:0007010	cytoskeleton organization	8.470527e-4
GO:0003008	system process	8.673884e-4
GO:0048385	regulation of retinoic acid receptor signaling pathway	8.755265e-4
GO:0010738	regulation of protein kinase A signaling cascade	8.801684e-4
GO:0010941	regulation of cell death	9.175199e-4
GO:0070848	response to growth factor stimulus	9.178472e-4
GO:0018293	protein-FAD linkage	9.348013e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	9.348013e-4
GO:0006953	acute-phase response	9.405978e-4
GO:0032516	positive regulation of phosphoprotein phosphatase activity	9.562836e-4
GO:0007603	phototransduction, visible light	9.562836e-4
GO:0002819	regulation of adaptive immune response	9.574057e-4
GO:0032461	positive regulation of protein oligomerization	9.738099e-4
GO:0060445	branching involved in salivary gland morphogenesis	9.823929e-4
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	9.857477e-4
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	9.978277e-4
GO:0021881	Wnt receptor signaling pathway involved in forebrain neuron fate commitment	1.003048e-3
GO:0007611	learning or memory	1.010264e-3
GO:0006212	uracil catabolic process	1.014280e-3
GO:0006210	thymine catabolic process	1.014280e-3
GO:0042981	regulation of apoptosis	1.017459e-3
GO:0065008	regulation of biological quality	1.032114e-3
GO:0000086	G2/M transition of mitotic cell cycle	1.046936e-3
GO:0051893	regulation of focal adhesion assembly	1.081419e-3
GO:0006564	L-serine biosynthetic process	1.096612e-3
GO:0044267	cellular protein metabolic process	1.098756e-3
GO:0001936	regulation of endothelial cell proliferation	1.102199e-3
GO:0016569	covalent chromatin modification	1.118901e-3
GO:0022008	neurogenesis	1.121500e-3
GO:0070670	response to interleukin-4	1.129782e-3
GO:0008210	estrogen metabolic process	1.144195e-3
GO:0031639	plasminogen activation	1.146476e-3
GO:0050830	defense response to Gram-positive bacterium	1.163478e-3
GO:0048667	cell morphogenesis involved in neuron differentiation	1.170084e-3
GO:0016226	iron-sulfur cluster assembly	1.198487e-3
GO:0006447	regulation of translational initiation by iron	1.200273e-3
GO:0010743	regulation of macrophage derived foam cell differentiation	1.219529e-3
GO:0071956	cellular component maintenance at cellular level	1.274425e-3
GO:2000379	positive regulation of reactive oxygen species metabolic process	1.284451e-3
GO:0021915	neural tube development	1.313251e-3
GO:0002821	positive regulation of adaptive immune response	1.357829e-3
GO:0019538	protein metabolic process	1.370982e-3
GO:0043241	protein complex disassembly	1.429308e-3
GO:0043501	skeletal muscle adaptation	1.438336e-3
GO:0019264	glycine biosynthetic process from serine	1.451130e-3
GO:0002576	platelet degranulation	1.460351e-3
GO:0051131	chaperone-mediated protein complex assembly	1.474924e-3
GO:0035921	desmosome disassembly	1.505368e-3
GO:0070563	negative regulation of vitamin D receptor signaling pathway	1.505368e-3
GO:0050905	neuromuscular process	1.508585e-3
GO:0021781	glial cell fate commitment	1.520165e-3
GO:0007610	behavior	1.540294e-3
GO:0043412	macromolecule modification	1.552537e-3
GO:0000117	regulation of transcription involved in G2/M-phase of mitotic cell cycle	1.559512e-3
GO:0010755	regulation of plasminogen activation	1.605121e-3
GO:0032236	positive regulation of calcium ion transport via store-operated calcium channel activity	1.636784e-3
GO:0031104	dendrite regeneration	1.636950e-3
GO:0016571	histone methylation	1.664542e-3
GO:0048660	regulation of smooth muscle cell proliferation	1.672413e-3
GO:0009084	glutamine family amino acid biosynthetic process	1.677199e-3
GO:0048262	determination of dorsal/ventral asymmetry	1.696774e-3
GO:0010646	regulation of cell communication	1.713373e-3
GO:0031579	membrane raft organization	1.722870e-3
GO:0035458	cellular response to interferon-beta	1.728136e-3
GO:0045663	positive regulation of myoblast differentiation	1.734020e-3
GO:0015918	sterol transport	1.808166e-3
GO:2000334	positive regulation of blood microparticle formation	1.815443e-3
GO:0019859	thymine metabolic process	1.815443e-3
GO:0060555	induction of necroptosis by extracellular signals	1.823239e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.848894e-3
GO:0060677	ureteric bud elongation	1.891903e-3
GO:0044070	regulation of anion transport	1.906399e-3
GO:0006780	uroporphyrinogen III biosynthetic process	1.917898e-3
GO:0035414	negative regulation of catenin import into nucleus	1.936307e-3
GO:0071363	cellular response to growth factor stimulus	1.941319e-3
GO:0045994	positive regulation of translational initiation by iron	2.000405e-3
GO:0002037	negative regulation of L-glutamate transport	2.000405e-3
GO:0019230	proprioception	2.032332e-3
GO:0048523	negative regulation of cellular process	2.037374e-3
GO:2000121	regulation of removal of superoxide radicals	2.038179e-3
GO:0019935	cyclic-nucleotide-mediated signaling	2.072561e-3
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2.078412e-3
GO:0006563	L-serine metabolic process	2.103237e-3
GO:0006642	triglyceride mobilization	2.108595e-3
GO:0006491	N-glycan processing	2.108595e-3
GO:0048010	vascular endothelial growth factor receptor signaling pathway	2.115701e-3
GO:0055114	oxidation-reduction process	2.117709e-3
GO:0006513	protein monoubiquitination	2.149730e-3
GO:0007597	blood coagulation, intrinsic pathway	2.213004e-3
GO:0060009	Sertoli cell development	2.229437e-3
GO:0022411	cellular component disassembly	2.251026e-3
GO:0006693	prostaglandin metabolic process	2.279744e-3
GO:0042758	long-chain fatty acid catabolic process	2.281288e-3
GO:0042413	carnitine catabolic process	2.281288e-3
GO:0007409	axonogenesis	2.283204e-3
GO:0048769	sarcomerogenesis	2.291300e-3
GO:0072376	protein activation cascade	2.339980e-3
GO:0043313	regulation of neutrophil degranulation	2.345536e-3
GO:0051895	negative regulation of focal adhesion assembly	2.386720e-3
GO:0032423	regulation of mismatch repair	2.395211e-3
GO:0032608	interferon-beta production	2.402487e-3
GO:0010825	positive regulation of centrosome duplication	2.402487e-3
GO:0030036	actin cytoskeleton organization	2.426681e-3
GO:0014866	skeletal myofibril assembly	2.437278e-3
GO:0009064	glutamine family amino acid metabolic process	2.470882e-3
GO:0030029	actin filament-based process	2.471181e-3
GO:0016310	phosphorylation	2.486500e-3
GO:0071844	cellular component assembly at cellular level	2.497770e-3
GO:0072033	renal vesicle formation	2.513125e-3
GO:0045870	positive regulation of retroviral genome replication	2.517575e-3
GO:0051043	regulation of membrane protein ectodomain proteolysis	2.527669e-3
GO:0048468	cell development	2.537813e-3
GO:0019220	regulation of phosphate metabolic process	2.565139e-3
GO:0043170	macromolecule metabolic process	2.578008e-3
GO:0032680	regulation of tumor necrosis factor production	2.599509e-3
GO:0035771	interleukin-4-mediated signaling pathway	2.607142e-3
GO:0010839	negative regulation of keratinocyte proliferation	2.607142e-3
GO:0014050	negative regulation of glutamate secretion	2.632263e-3
GO:0042176	regulation of protein catabolic process	2.633795e-3
GO:0010824	regulation of centrosome duplication	2.663370e-3
GO:0034441	plasma lipoprotein particle oxidation	2.664659e-3
GO:0001544	initiation of primordial ovarian follicle growth	2.664659e-3
GO:0009063	cellular amino acid catabolic process	2.673904e-3
GO:0070103	regulation of interleukin-6-mediated signaling pathway	2.736503e-3
GO:0070104	negative regulation of interleukin-6-mediated signaling pathway	2.753424e-3
GO:0006145	purine base catabolic process	2.753424e-3
GO:0043652	engulfment of apoptotic cell	2.780203e-3
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.780203e-3
GO:0010754	negative regulation of cGMP-mediated signaling	2.780203e-3
GO:0010751	negative regulation of nitric oxide mediated signal transduction	2.780203e-3
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	2.780203e-3
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.787715e-3
GO:0051660	establishment of centrosome localization	2.965026e-3
GO:0021540	corpus callosum morphogenesis	2.965026e-3
GO:0050877	neurological system process	2.967181e-3
GO:0022607	cellular component assembly	2.998309e-3
GO:0050890	cognition	3.002204e-3
GO:0032369	negative regulation of lipid transport	3.011065e-3
GO:0050806	positive regulation of synaptic transmission	3.022831e-3
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	3.037345e-3
GO:0051004	regulation of lipoprotein lipase activity	3.044875e-3
GO:0042417	dopamine metabolic process	3.091704e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	3.134884e-3
GO:0007050	cell cycle arrest	3.213242e-3
GO:0001556	oocyte maturation	3.247277e-3
GO:0007007	inner mitochondrial membrane organization	3.275464e-3
GO:0051481	reduction of cytosolic calcium ion concentration	3.298428e-3
GO:0046104	thymidine metabolic process	3.343101e-3
GO:0008628	induction of apoptosis by hormones	3.343101e-3
GO:0071103	DNA conformation change	3.498325e-3
GO:0009088	threonine biosynthetic process	3.509432e-3
GO:2000345	regulation of hepatocyte proliferation	3.537970e-3
GO:0010035	response to inorganic substance	3.576630e-3
GO:0006687	glycosphingolipid metabolic process	3.587229e-3
GO:0060100	positive regulation of phagocytosis, engulfment	3.650701e-3
GO:0009615	response to virus	3.766113e-3
GO:0007435	salivary gland morphogenesis	3.831271e-3
GO:0034641	cellular nitrogen compound metabolic process	3.881140e-3
GO:0001573	ganglioside metabolic process	3.889142e-3
GO:0034393	positive regulation of smooth muscle cell apoptosis	3.941048e-3
GO:0048699	generation of neurons	3.942636e-3
GO:0006689	ganglioside catabolic process	3.953603e-3
GO:0010757	negative regulation of plasminogen activation	3.970528e-3
GO:0071447	cellular response to hydroperoxide	4.024367e-3
GO:0021797	forebrain anterior/posterior pattern specification	4.054391e-3
GO:0071025	RNA surveillance	4.093353e-3
GO:0010226	response to lithium ion	4.178415e-3
GO:0060271	cilium morphogenesis	4.217696e-3
GO:0070507	regulation of microtubule cytoskeleton organization	4.273069e-3
GO:0034498	early endosome to Golgi transport	4.346712e-3
GO:0015939	pantothenate metabolic process	4.412012e-3
GO:0044085	cellular component biogenesis	4.427462e-3
GO:0016192	vesicle-mediated transport	4.442030e-3
GO:0000904	cell morphogenesis involved in differentiation	4.465651e-3
GO:0032606	type I interferon production	4.525116e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	4.527374e-3
GO:0030301	cholesterol transport	4.538901e-3
GO:0006887	exocytosis	4.558892e-3
GO:0051135	positive regulation of NK T cell activation	4.640365e-3
GO:0071636	positive regulation of transforming growth factor beta production	4.666773e-3
GO:2000143	negative regulation of transcription initiation, DNA-dependent	4.671805e-3
GO:0000416	positive regulation of histone H3-K36 methylation	4.671805e-3
GO:0009060	aerobic respiration	4.693213e-3
GO:0051325	interphase	4.706352e-3
GO:0060291	long-term synaptic potentiation	4.772178e-3
GO:0007015	actin filament organization	4.801167e-3
GO:0015911	plasma membrane long-chain fatty acid transport	4.805839e-3
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	4.841312e-3
GO:0071675	regulation of mononuclear cell migration	4.944728e-3
GO:0043666	regulation of phosphoprotein phosphatase activity	4.954897e-3
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	4.969932e-3
GO:0010888	negative regulation of lipid storage	4.972315e-3
GO:0010759	positive regulation of macrophage chemotaxis	5.044105e-3
GO:0061041	regulation of wound healing	5.064014e-3
GO:0042044	fluid transport	5.107678e-3
GO:0051179	localization	5.113547e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	5.127544e-3
GO:0048519	negative regulation of biological process	5.144543e-3
GO:0060548	negative regulation of cell death	5.150601e-3
GO:0032800	receptor biosynthetic process	5.174388e-3
GO:0070194	synaptonemal complex disassembly	5.176763e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	5.176763e-3
GO:0015886	heme transport	5.363044e-3
GO:0045597	positive regulation of cell differentiation	5.412832e-3
GO:0019934	cGMP-mediated signaling	5.518793e-3
GO:0070271	protein complex biogenesis	5.520107e-3
GO:0002437	inflammatory response to antigenic stimulus	5.560976e-3
GO:0032501	multicellular organismal process	5.633189e-3
GO:0021553	olfactory nerve development	5.644373e-3
GO:0090304	nucleic acid metabolic process	5.646863e-3
GO:0032464	positive regulation of protein homooligomerization	5.674281e-3
GO:0046322	negative regulation of fatty acid oxidation	5.696284e-3
GO:0009586	rhodopsin mediated phototransduction	5.760490e-3
GO:0031099	regeneration	5.820401e-3
GO:0035518	histone H2A monoubiquitination	5.850501e-3
GO:0070265	necrotic cell death	5.893529e-3
GO:0015855	pyrimidine base transport	5.893529e-3
GO:0045657	positive regulation of monocyte differentiation	5.893529e-3
GO:0006461	protein complex assembly	5.933521e-3
GO:0000082	G1/S transition of mitotic cell cycle	5.980342e-3
GO:0019254	carnitine metabolic process, CoA-linked	5.998672e-3
GO:0051568	histone H3-K4 methylation	6.060659e-3
GO:0032237	activation of store-operated calcium channel activity	6.092430e-3
GO:2000503	positive regulation of natural killer cell chemotaxis	6.115948e-3
GO:2000513	positive regulation of granzyme A production	6.115948e-3
GO:2000518	negative regulation of T-helper 1 cell activation	6.115948e-3
GO:2000538	positive regulation of B cell chemotaxis	6.115948e-3
GO:0071663	positive regulation of granzyme B production	6.115948e-3
GO:2000412	positive regulation of thymocyte migration	6.115948e-3
GO:0035740	CD8-positive, alpha-beta T cell proliferation	6.115948e-3
GO:0035739	CD4-positive, alpha-beta T cell proliferation	6.115948e-3
GO:0035744	T-helper 1 cell cytokine production	6.115948e-3
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	6.134839e-3
GO:0043031	negative regulation of macrophage activation	6.176990e-3
GO:0006398	histone mRNA 3'-end processing	6.176990e-3
GO:0045218	zonula adherens maintenance	6.197383e-3
GO:0097035	regulation of membrane lipid distribution	6.217684e-3
GO:0051917	regulation of fibrinolysis	6.217684e-3
GO:0042177	negative regulation of protein catabolic process	6.346005e-3
GO:0071310	cellular response to organic substance	6.373561e-3
GO:0010758	regulation of macrophage chemotaxis	6.394005e-3
GO:0047496	vesicle transport along microtubule	6.421503e-3
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	6.539118e-3
GO:0032007	negative regulation of TOR signaling cascade	6.539118e-3
GO:0015721	bile acid and bile salt transport	6.581888e-3
GO:0006958	complement activation, classical pathway	6.721610e-3
GO:0042489	negative regulation of odontogenesis of dentine-containing tooth	6.752511e-3
GO:0032959	inositol trisphosphate biosynthetic process	6.764335e-3
GO:0035924	cellular response to vascular endothelial growth factor stimulus	6.784076e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	6.793407e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	6.809448e-3
GO:0032958	inositol phosphate biosynthetic process	6.861009e-3
GO:0030049	muscle filament sliding	6.901812e-3
GO:0007431	salivary gland development	6.987668e-3
GO:0010517	regulation of phospholipase activity	7.140682e-3
GO:0070683	mitotic cell cycle G2/M transition decatenation checkpoint	7.140866e-3
GO:0021984	adenohypophysis development	7.155497e-3
GO:0032878	regulation of establishment or maintenance of cell polarity	7.195241e-3
GO:0051707	response to other organism	7.274344e-3
GO:0006807	nitrogen compound metabolic process	7.308190e-3
GO:0016070	RNA metabolic process	7.334605e-3
GO:0030194	positive regulation of blood coagulation	7.383354e-3
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	7.440812e-3
GO:0016082	synaptic vesicle priming	7.453156e-3
GO:0001766	membrane raft polarization	7.453156e-3
GO:0002376	immune system process	7.489454e-3
GO:0001843	neural tube closure	7.518477e-3
GO:0001960	negative regulation of cytokine-mediated signaling pathway	7.589102e-3
GO:0070294	renal sodium ion absorption	7.628792e-3
GO:0030157	pancreatic juice secretion	7.642904e-3
GO:0009584	detection of visible light	7.663680e-3
GO:0006796	phosphate-containing compound metabolic process	7.710751e-3
GO:0031119	tRNA pseudouridine synthesis	7.773060e-3
GO:0035082	axoneme assembly	7.879206e-3
GO:0006265	DNA topological change	7.879206e-3
GO:0090291	negative regulation of osteoclast proliferation	7.901997e-3
GO:2000347	positive regulation of hepatocyte proliferation	7.901997e-3
GO:2000349	negative regulation of CD40 signaling pathway	7.901997e-3
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	7.901997e-3
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	7.901997e-3
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	7.901997e-3
GO:0072573	tolerance induction to lipopolysaccharide	7.901997e-3
GO:0031100	organ regeneration	7.970406e-3
GO:0071622	regulation of granulocyte chemotaxis	7.988967e-3
GO:0043069	negative regulation of programmed cell death	8.004226e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	8.027929e-3
GO:0035330	regulation of hippo signaling cascade	8.028424e-3
GO:0006266	DNA ligation	8.070481e-3
GO:0060216	definitive hemopoiesis	8.074661e-3
GO:0006629	lipid metabolic process	8.100420e-3
GO:0006833	water transport	8.112016e-3
GO:0006396	RNA processing	8.183043e-3
GO:0051318	G1 phase	8.332968e-3
GO:0030838	positive regulation of actin filament polymerization	8.363356e-3
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	8.407152e-3
GO:0042308	negative regulation of protein import into nucleus	8.414697e-3
GO:0042953	lipoprotein transport	8.430832e-3
GO:0021935	cerebellar granule cell precursor tangential migration	8.454185e-3
GO:0033151	V(D)J recombination	8.485596e-3
GO:0032006	regulation of TOR signaling cascade	8.554943e-3
GO:0009653	anatomical structure morphogenesis	8.560157e-3
GO:0030162	regulation of proteolysis	8.586292e-3
GO:0048566	embryonic digestive tract development	8.642603e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	8.712382e-3
GO:0060606	tube closure	8.757741e-3
GO:0001841	neural tube formation	8.840494e-3
GO:0001774	microglial cell activation	8.841722e-3
GO:0050908	detection of light stimulus involved in visual perception	8.867130e-3
GO:0050820	positive regulation of coagulation	8.874496e-3
GO:0007030	Golgi organization	8.883897e-3
GO:0060218	hemopoietic stem cell differentiation	8.909164e-3
GO:0032924	activin receptor signaling pathway	8.913478e-3
GO:0008202	steroid metabolic process	8.916124e-3
GO:0048853	forebrain morphogenesis	8.916126e-3
GO:0016567	protein ubiquitination	9.099798e-3
GO:0010815	bradykinin catabolic process	9.110299e-3
GO:0001696	gastric acid secretion	9.110299e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	9.131767e-3
GO:0032411	positive regulation of transporter activity	9.134042e-3
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	9.212446e-3
GO:0007525	somatic muscle development	9.222318e-3
GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback	9.222318e-3
GO:0006479	protein methylation	9.288813e-3
GO:0030168	platelet activation	9.310780e-3
GO:0010955	negative regulation of protein processing	9.338543e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050892	intestinal absorption	4.685122e-12
GO:0009410	response to xenobiotic stimulus	5.698804e-9
GO:0022600	digestive system process	4.660465e-8
GO:0060282	positive regulation of oocyte development	1.165781e-7
GO:0060281	regulation of oocyte development	1.165781e-7
GO:0032814	regulation of natural killer cell activation	2.022310e-7
GO:0001916	positive regulation of T cell mediated cytotoxicity	2.552435e-7
GO:0032423	regulation of mismatch repair	5.461325e-7
GO:0006805	xenobiotic metabolic process	6.315976e-7
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	9.142123e-7
GO:0001914	regulation of T cell mediated cytotoxicity	1.091234e-6
GO:0032890	regulation of organic acid transport	1.100128e-6
GO:0006651	diacylglycerol biosynthetic process	1.107074e-6
GO:0002699	positive regulation of immune effector process	2.318281e-6
GO:0014050	negative regulation of glutamate secretion	2.557911e-6
GO:0034394	protein localization at cell surface	2.668794e-6
GO:0002439	chronic inflammatory response to antigenic stimulus	6.672993e-6
GO:0032816	positive regulation of natural killer cell activation	8.364515e-6
GO:0008210	estrogen metabolic process	9.217491e-6
GO:0051707	response to other organism	9.443458e-6
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	9.510344e-6
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	9.809774e-6
GO:0006937	regulation of muscle contraction	1.009603e-5
GO:0000103	sulfate assimilation	1.044249e-5
GO:0000724	double-strand break repair via homologous recombination	1.151443e-5
GO:0006108	malate metabolic process	1.265383e-5
GO:0009617	response to bacterium	1.435492e-5
GO:0046635	positive regulation of alpha-beta T cell activation	1.495825e-5
GO:0000725	recombinational repair	1.768439e-5
GO:0001910	regulation of leukocyte mediated cytotoxicity	1.913666e-5
GO:0055119	relaxation of cardiac muscle	2.127223e-5
GO:0034754	cellular hormone metabolic process	2.180699e-5
GO:0042445	hormone metabolic process	2.233917e-5
GO:0010519	negative regulation of phospholipase activity	2.289268e-5
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	2.931994e-5
GO:0018960	4-nitrophenol metabolic process	2.932268e-5
GO:0010574	regulation of vascular endothelial growth factor production	3.045458e-5
GO:0010661	positive regulation of muscle cell apoptosis	3.501416e-5
GO:0009635	response to herbicide	3.501416e-5
GO:0006787	porphyrin-containing compound catabolic process	3.618828e-5
GO:0001887	selenium compound metabolic process	3.618828e-5
GO:0090257	regulation of muscle system process	3.664499e-5
GO:0042472	inner ear morphogenesis	3.675694e-5
GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	3.939187e-5
GO:0046600	negative regulation of centriole replication	4.179163e-5
GO:0009607	response to biotic stimulus	4.413145e-5
GO:0032496	response to lipopolysaccharide	4.469877e-5
GO:0002711	positive regulation of T cell mediated immunity	4.538283e-5
GO:0051187	cofactor catabolic process	4.564497e-5
GO:0031343	positive regulation of cell killing	4.584334e-5
GO:0034393	positive regulation of smooth muscle cell apoptosis	4.973769e-5
GO:0002697	regulation of immune effector process	5.284037e-5
GO:0042471	ear morphogenesis	5.827423e-5
GO:0003008	system process	5.845176e-5
GO:0051135	positive regulation of NK T cell activation	5.905437e-5
GO:0090007	regulation of mitotic anaphase	6.452963e-5
GO:2000381	negative regulation of mesoderm development	7.149856e-5
GO:0031341	regulation of cell killing	7.334646e-5
GO:0006942	regulation of striated muscle contraction	8.237156e-5
GO:0048660	regulation of smooth muscle cell proliferation	8.855679e-5
GO:0043491	protein kinase B signaling cascade	8.876889e-5
GO:0002237	response to molecule of bacterial origin	9.958149e-5
GO:0061338	atrioventricular node impulse conduction delay	1.000411e-4
GO:0055118	negative regulation of cardiac muscle contraction	1.019816e-4
GO:0002437	inflammatory response to antigenic stimulus	1.039075e-4
GO:0070164	negative regulation of adiponectin secretion	1.145796e-4
GO:0042489	negative regulation of odontogenesis of dentine-containing tooth	1.145796e-4
GO:0035505	positive regulation of myosin light chain kinase activity	1.145796e-4
GO:0009052	pentose-phosphate shunt, non-oxidative branch	1.160881e-4
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	1.185962e-4
GO:0007144	female meiosis I	1.262846e-4
GO:0048745	smooth muscle tissue development	1.314036e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	1.353536e-4
GO:0030168	platelet activation	1.362473e-4
GO:0002703	regulation of leukocyte mediated immunity	1.364399e-4
GO:0042742	defense response to bacterium	1.395499e-4
GO:0031349	positive regulation of defense response	1.429420e-4
GO:0032425	positive regulation of mismatch repair	1.452482e-4
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	1.594613e-4
GO:2000191	regulation of fatty acid transport	1.749931e-4
GO:0046069	cGMP catabolic process	1.772395e-4
GO:0030593	neutrophil chemotaxis	1.805016e-4
GO:0051704	multi-organism process	1.823360e-4
GO:0002329	pre-B cell differentiation	1.848942e-4
GO:0010817	regulation of hormone levels	1.898943e-4
GO:0030178	negative regulation of Wnt receptor signaling pathway	1.915361e-4
GO:0046634	regulation of alpha-beta T cell activation	1.937164e-4
GO:0032700	negative regulation of interleukin-17 production	1.966546e-4
GO:0071436	sodium ion export	2.013135e-4
GO:0033152	immunoglobulin V(D)J recombination	2.021105e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	2.022984e-4
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	2.196086e-4
GO:0051984	positive regulation of chromosome segregation	2.253916e-4
GO:0032075	positive regulation of nuclease activity	2.363217e-4
GO:0035967	cellular response to topologically incorrect protein	2.489322e-4
GO:0045907	positive regulation of vasoconstriction	2.493753e-4
GO:0032185	septin cytoskeleton organization	2.505642e-4
GO:0019370	leukotriene biosynthetic process	2.658636e-4
GO:0010963	regulation of L-arginine import	2.691725e-4
GO:0032892	positive regulation of organic acid transport	2.699496e-4
GO:0002426	immunoglobulin production in mucosal tissue	2.718542e-4
GO:0010517	regulation of phospholipase activity	2.819099e-4
GO:0046456	icosanoid biosynthetic process	2.828387e-4
GO:0010575	positive regulation vascular endothelial growth factor production	2.949395e-4
GO:0007586	digestion	3.058104e-4
GO:2001054	negative regulation of mesenchymal cell apoptosis	3.086424e-4
GO:0050796	regulation of insulin secretion	3.098651e-4
GO:0061337	cardiac conduction	3.277149e-4
GO:0042446	hormone biosynthetic process	3.542119e-4
GO:0032000	positive regulation of fatty acid beta-oxidation	3.545226e-4
GO:0007614	short-term memory	3.545226e-4
GO:0030968	endoplasmic reticulum unfolded protein response	3.558758e-4
GO:0090276	regulation of peptide hormone secretion	3.664235e-4
GO:0021935	cerebellar granule cell precursor tangential migration	3.666509e-4
GO:0006104	succinyl-CoA metabolic process	3.666509e-4
GO:0051645	Golgi localization	3.693632e-4
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	3.698287e-4
GO:0031023	microtubule organizing center organization	3.763329e-4
GO:0055114	oxidation-reduction process	4.157818e-4
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	4.284444e-4
GO:0006636	unsaturated fatty acid biosynthetic process	4.411179e-4
GO:0048662	negative regulation of smooth muscle cell proliferation	4.552604e-4
GO:0006749	glutathione metabolic process	4.709202e-4
GO:2000078	positive regulation of type B pancreatic cell development	4.725708e-4
GO:0051955	regulation of amino acid transport	4.778271e-4
GO:0006463	steroid hormone receptor complex assembly	4.919762e-4
GO:0080134	regulation of response to stress	5.068166e-4
GO:0070861	regulation of protein exit from endoplasmic reticulum	5.166637e-4
GO:0071955	recycling endosome to Golgi transport	5.166637e-4
GO:0034499	late endosome to Golgi transport	5.166637e-4
GO:0031129	inductive cell-cell signaling	5.166637e-4
GO:0001736	establishment of planar polarity	5.180455e-4
GO:0045932	negative regulation of muscle contraction	5.215746e-4
GO:0006750	glutathione biosynthetic process	5.257440e-4
GO:0001879	detection of yeast	5.467799e-4
GO:0015721	bile acid and bile salt transport	5.538792e-4
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.713107e-4
GO:0044237	cellular metabolic process	5.955096e-4
GO:0055117	regulation of cardiac muscle contraction	6.138706e-4
GO:0043277	apoptotic cell clearance	6.158505e-4
GO:0031947	negative regulation of glucocorticoid biosynthetic process	6.450481e-4
GO:0019693	ribose phosphate metabolic process	6.632570e-4
GO:0032729	positive regulation of interferon-gamma production	7.380179e-4
GO:0034391	regulation of smooth muscle cell apoptosis	7.820227e-4
GO:0032784	regulation of transcription elongation, DNA-dependent	8.129648e-4
GO:0002791	regulation of peptide secretion	8.345084e-4
GO:0016045	detection of bacterium	8.587652e-4
GO:0032872	regulation of stress-activated MAPK cascade	8.648059e-4
GO:0007164	establishment of tissue polarity	8.648059e-4
GO:0001672	regulation of chromatin assembly or disassembly	8.765866e-4
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	8.828576e-4
GO:0050996	positive regulation of lipid catabolic process	8.952103e-4
GO:0006952	defense response	8.989915e-4
GO:0033151	V(D)J recombination	9.004824e-4
GO:0051241	negative regulation of multicellular organismal process	9.010642e-4
GO:0010983	positive regulation of high-density lipoprotein particle clearance	9.348516e-4
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	9.348516e-4
GO:0047484	regulation of response to osmotic stress	9.388135e-4
GO:0006691	leukotriene metabolic process	9.390831e-4
GO:0006393	termination of mitochondrial transcription	9.511596e-4
GO:0045988	negative regulation of striated muscle contraction	1.018890e-3
GO:0061181	regulation of chondrocyte development	1.065444e-3
GO:0001556	oocyte maturation	1.086605e-3
GO:0010669	epithelial structure maintenance	1.103300e-3
GO:0048016	inositol phosphate-mediated signaling	1.131669e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	1.159485e-3
GO:0032787	monocarboxylic acid metabolic process	1.161667e-3
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	1.221261e-3
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	1.221261e-3
GO:0002544	chronic inflammatory response	1.233262e-3
GO:0006940	regulation of smooth muscle contraction	1.246508e-3
GO:0032874	positive regulation of stress-activated MAPK cascade	1.250657e-3
GO:0002886	regulation of myeloid leukocyte mediated immunity	1.258471e-3
GO:0010613	positive regulation of cardiac muscle hypertrophy	1.265882e-3
GO:0048839	inner ear development	1.277117e-3
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	1.278258e-3
GO:0002709	regulation of T cell mediated immunity	1.320924e-3
GO:0051179	localization	1.323490e-3
GO:0006288	base-excision repair, DNA ligation	1.337795e-3
GO:0006014	D-ribose metabolic process	1.354261e-3
GO:0060043	regulation of cardiac muscle cell proliferation	1.416453e-3
GO:0090075	relaxation of muscle	1.419033e-3
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	1.444691e-3
GO:0060420	regulation of heart growth	1.498501e-3
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.512522e-3
GO:0045401	positive regulation of interleukin-3 biosynthetic process	1.512522e-3
GO:0051131	chaperone-mediated protein complex assembly	1.526619e-3
GO:0006082	organic acid metabolic process	1.533747e-3
GO:0055021	regulation of cardiac muscle tissue growth	1.540425e-3
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.558177e-3
GO:0014743	regulation of muscle hypertrophy	1.576016e-3
GO:0010863	positive regulation of phospholipase C activity	1.722618e-3
GO:0009264	deoxyribonucleotide catabolic process	1.735045e-3
GO:0008154	actin polymerization or depolymerization	1.742374e-3
GO:0050896	response to stimulus	1.775518e-3
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.781569e-3
GO:0009125	nucleoside monophosphate catabolic process	1.787267e-3
GO:0033280	response to vitamin D	1.807734e-3
GO:0007202	activation of phospholipase C activity	1.843337e-3
GO:0006084	acetyl-CoA metabolic process	1.902698e-3
GO:0046339	diacylglycerol metabolic process	1.919427e-3
GO:0015701	bicarbonate transport	1.919427e-3
GO:0071477	cellular hypotonic salinity response	1.954682e-3
GO:0032308	positive regulation of prostaglandin secretion	1.964347e-3
GO:0046599	regulation of centriole replication	1.964347e-3
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	1.964347e-3
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	2.005663e-3
GO:0034626	fatty acid elongation, polyunsaturated fatty acid	2.010003e-3
GO:0031929	TOR signaling cascade	2.010003e-3
GO:0006986	response to unfolded protein	2.029529e-3
GO:0045588	positive regulation of gamma-delta T cell differentiation	2.032688e-3
GO:0007157	heterophilic cell-cell adhesion	2.033319e-3
GO:0021589	cerebellum structural organization	2.084048e-3
GO:0045947	negative regulation of translational initiation	2.124912e-3
GO:0070163	regulation of adiponectin secretion	2.141842e-3
GO:0010986	positive regulation of lipoprotein particle clearance	2.141842e-3
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	2.141842e-3
GO:0046851	negative regulation of bone remodeling	2.179363e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	2.190076e-3
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	2.215881e-3
GO:0048304	positive regulation of isotype switching to IgG isotypes	2.233648e-3
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	2.363964e-3
GO:0002706	regulation of lymphocyte mediated immunity	2.366051e-3
GO:0001819	positive regulation of cytokine production	2.399174e-3
GO:0002639	positive regulation of immunoglobulin production	2.400735e-3
GO:0010501	RNA secondary structure unwinding	2.415827e-3
GO:0009204	deoxyribonucleoside triphosphate catabolic process	2.422310e-3
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	2.442690e-3
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	2.442690e-3
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	2.501205e-3
GO:0046640	regulation of alpha-beta T cell proliferation	2.512934e-3
GO:0006690	icosanoid metabolic process	2.523251e-3
GO:0050729	positive regulation of inflammatory response	2.648355e-3
GO:0042180	cellular ketone metabolic process	2.677008e-3
GO:0019752	carboxylic acid metabolic process	2.678231e-3
GO:0032660	regulation of interleukin-17 production	2.782516e-3
GO:0033299	secretion of lysosomal enzymes	2.798718e-3
GO:0006310	DNA recombination	2.798898e-3
GO:0043583	ear development	2.799957e-3
GO:0007204	elevation of cytosolic calcium ion concentration	2.836122e-3
GO:0006670	sphingosine metabolic process	2.859889e-3
GO:0043506	regulation of JUN kinase activity	2.870751e-3
GO:0000003	reproduction	2.891203e-3
GO:0042167	heme catabolic process	2.946560e-3
GO:0002678	positive regulation of chronic inflammatory response	2.949487e-3
GO:0001738	morphogenesis of a polarized epithelium	2.987559e-3
GO:0030901	midbrain development	3.015333e-3
GO:0006686	sphingomyelin biosynthetic process	3.047311e-3
GO:0060441	epithelial tube branching involved in lung morphogenesis	3.057333e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	3.068947e-3
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	3.116662e-3
GO:0002026	regulation of the force of heart contraction	3.128118e-3
GO:0006672	ceramide metabolic process	3.159441e-3
GO:0032069	regulation of nuclease activity	3.231213e-3
GO:0051094	positive regulation of developmental process	3.376769e-3
GO:0045860	positive regulation of protein kinase activity	3.382506e-3
GO:0046068	cGMP metabolic process	3.403980e-3
GO:0042832	defense response to protozoan	3.406029e-3
GO:0003416	endochondral bone growth	3.406029e-3
GO:0031581	hemidesmosome assembly	3.451459e-3
GO:0009214	cyclic nucleotide catabolic process	3.469559e-3
GO:0060662	salivary gland cavitation	3.470262e-3
GO:0007218	neuropeptide signaling pathway	3.481101e-3
GO:0003013	circulatory system process	3.521640e-3
GO:0051967	negative regulation of synaptic transmission, glutamatergic	3.533003e-3
GO:0050880	regulation of blood vessel size	3.545277e-3
GO:0060032	notochord regression	3.551712e-3
GO:0003018	vascular process in circulatory system	3.594666e-3
GO:0031347	regulation of defense response	3.614174e-3
GO:0042129	regulation of T cell proliferation	3.622377e-3
GO:0035150	regulation of tube size	3.627076e-3
GO:0001657	ureteric bud development	3.666441e-3
GO:0050882	voluntary musculoskeletal movement	3.675462e-3
GO:0032320	positive regulation of Ras GTPase activity	3.827390e-3
GO:0045657	positive regulation of monocyte differentiation	3.852819e-3
GO:0033574	response to testosterone stimulus	3.859454e-3
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	3.912604e-3
GO:0042269	regulation of natural killer cell mediated cytotoxicity	3.912604e-3
GO:0006099	tricarboxylic acid cycle	3.922363e-3
GO:0002676	regulation of chronic inflammatory response	4.021886e-3
GO:0009615	response to virus	4.038256e-3
GO:0048302	regulation of isotype switching to IgG isotypes	4.101536e-3
GO:0070302	regulation of stress-activated protein kinase signaling cascade	4.151799e-3
GO:0001817	regulation of cytokine production	4.154925e-3
GO:0050702	interleukin-1 beta secretion	4.180530e-3
GO:0043471	regulation of cellular carbohydrate catabolic process	4.190467e-3
GO:0009268	response to pH	4.199965e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	4.265723e-3
GO:0051297	centrosome organization	4.296019e-3
GO:0034113	heterotypic cell-cell adhesion	4.375914e-3
GO:0031340	positive regulation of vesicle fusion	4.567787e-3
GO:0030098	lymphocyte differentiation	4.653361e-3
GO:0033674	positive regulation of kinase activity	4.727008e-3
GO:0030033	microvillus assembly	4.733200e-3
GO:0032611	interleukin-1 beta production	4.733200e-3
GO:0050794	regulation of cellular process	4.907788e-3
GO:0002837	regulation of immune response to tumor cell	4.928653e-3
GO:0010269	response to selenium ion	4.936731e-3
GO:0071472	cellular response to salt stress	5.003844e-3
GO:0001865	NK T cell differentiation	5.003844e-3
GO:0032633	interleukin-4 production	5.003844e-3
GO:0002821	positive regulation of adaptive immune response	5.006843e-3
GO:0042403	thyroid hormone metabolic process	5.082005e-3
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	5.188166e-3
GO:0055091	phospholipid homeostasis	5.292038e-3
GO:0035966	response to topologically incorrect protein	5.292417e-3
GO:0002637	regulation of immunoglobulin production	5.292417e-3
GO:0045830	positive regulation of isotype switching	5.299679e-3
GO:0014048	regulation of glutamate secretion	5.299679e-3
GO:0032793	positive regulation of CREB transcription factor activity	5.374657e-3
GO:0008152	metabolic process	5.413713e-3
GO:0045577	regulation of B cell differentiation	5.422904e-3
GO:2000009	negative regulation of protein localization at cell surface	5.475087e-3
GO:0019098	reproductive behavior	5.525349e-3
GO:0032649	regulation of interferon-gamma production	5.547644e-3
GO:0045454	cell redox homeostasis	5.582093e-3
GO:0016310	phosphorylation	5.684377e-3
GO:0008610	lipid biosynthetic process	5.727777e-3
GO:0043300	regulation of leukocyte degranulation	5.757519e-3
GO:0051103	DNA ligation involved in DNA repair	5.815980e-3
GO:0010464	regulation of mesenchymal cell proliferation	5.852696e-3
GO:0051017	actin filament bundle assembly	5.853364e-3
GO:0016539	intein-mediated protein splicing	5.859690e-3
GO:0050877	neurological system process	5.861931e-3
GO:0016575	histone deacetylation	5.948448e-3
GO:0070602	regulation of centromeric sister chromatid cohesion	5.990616e-3
GO:0050830	defense response to Gram-positive bacterium	6.047359e-3
GO:0031399	regulation of protein modification process	6.135672e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.145151e-3
GO:0065008	regulation of biological quality	6.153505e-3
GO:0046519	sphingoid metabolic process	6.170739e-3
GO:0051983	regulation of chromosome segregation	6.194113e-3
GO:0031503	protein complex localization	6.349913e-3
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	6.349913e-3
GO:0001562	response to protozoan	6.415250e-3
GO:0023057	negative regulation of signaling	6.416088e-3
GO:0010518	positive regulation of phospholipase activity	6.436669e-3
GO:0006776	vitamin A metabolic process	6.503223e-3
GO:0022414	reproductive process	6.601799e-3
GO:0072560	type B pancreatic cell maturation	6.648758e-3
GO:0055024	regulation of cardiac muscle tissue development	6.696196e-3
GO:0015870	acetylcholine transport	6.699923e-3
GO:0042221	response to chemical stimulus	6.733623e-3
GO:0046356	acetyl-CoA catabolic process	6.768245e-3
GO:0032754	positive regulation of interleukin-5 production	6.779079e-3
GO:0032370	positive regulation of lipid transport	6.786659e-3
GO:0006629	lipid metabolic process	6.792736e-3
GO:2000193	positive regulation of fatty acid transport	6.834391e-3
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	6.834391e-3
GO:0010648	negative regulation of cell communication	6.960536e-3
GO:0002456	T cell mediated immunity	6.982590e-3
GO:0006633	fatty acid biosynthetic process	7.105255e-3
GO:0034976	response to endoplasmic reticulum stress	7.177797e-3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	7.302731e-3
GO:0045410	positive regulation of interleukin-6 biosynthetic process	7.465942e-3
GO:0003341	cilium movement	7.465942e-3
GO:0032268	regulation of cellular protein metabolic process	7.486808e-3
GO:0046496	nicotinamide nucleotide metabolic process	7.514976e-3
GO:0035414	negative regulation of catenin import into nucleus	7.563117e-3
GO:0043507	positive regulation of JUN kinase activity	7.782592e-3
GO:2000384	negative regulation of ectoderm development	7.851698e-3
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	7.851698e-3
GO:0090161	Golgi ribbon formation	7.851698e-3
GO:0042574	retinal metabolic process	7.855703e-3
GO:0006206	pyrimidine base metabolic process	7.907914e-3
GO:0090103	cochlea morphogenesis	7.915619e-3
GO:0002521	leukocyte differentiation	8.063260e-3
GO:0051239	regulation of multicellular organismal process	8.083678e-3
GO:0010611	regulation of cardiac muscle hypertrophy	8.105145e-3
GO:0008347	glial cell migration	8.150987e-3
GO:0045088	regulation of innate immune response	8.157309e-3
GO:0015718	monocarboxylic acid transport	8.228115e-3
GO:0030423	targeting of mRNA for destruction involved in RNA interference	8.269599e-3
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	8.269599e-3
GO:0043406	positive regulation of MAP kinase activity	8.312715e-3
GO:0051347	positive regulation of transferase activity	8.325977e-3
GO:0048562	embryonic organ morphogenesis	8.369840e-3
GO:0009109	coenzyme catabolic process	8.404999e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	8.404999e-3
GO:0031998	regulation of fatty acid beta-oxidation	8.424818e-3
GO:0032736	positive regulation of interleukin-13 production	8.438929e-3
GO:0043043	peptide biosynthetic process	8.464120e-3
GO:0050855	regulation of B cell receptor signaling pathway	8.465033e-3
GO:0007340	acrosome reaction	8.465033e-3
GO:0006821	chloride transport	8.815842e-3
GO:0045911	positive regulation of DNA recombination	8.873180e-3
GO:0045162	clustering of voltage-gated sodium channels	8.995544e-3
GO:0006704	glucocorticoid biosynthetic process	9.053342e-3
GO:0045779	negative regulation of bone resorption	9.053342e-3
GO:0033043	regulation of organelle organization	9.117378e-3
GO:0009595	detection of biotic stimulus	9.370091e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	9.446261e-3
GO:0050852	T cell receptor signaling pathway	9.569353e-3
GO:0070327	thyroid hormone transport	9.577646e-3
GO:0045089	positive regulation of innate immune response	9.584161e-3
GO:0051054	positive regulation of DNA metabolic process	9.589910e-3
GO:0007417	central nervous system development	9.708856e-3
GO:0019368	fatty acid elongation, unsaturated fatty acid	9.795300e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	9.967914e-3
GO:0032849	positive regulation of cellular pH reduction	1.012577e-2
GO:0060155	platelet dense granule organization	1.012577e-2
GO:0071476	cellular hypotonic response	1.024271e-2
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.037944e-2
GO:0002385	mucosal immune response	1.051095e-2
GO:0045597	positive regulation of cell differentiation	1.054158e-2
GO:0009060	aerobic respiration	1.056748e-2
GO:0006950	response to stress	1.066307e-2
GO:0001960	negative regulation of cytokine-mediated signaling pathway	1.067767e-2
GO:0035725	sodium ion transmembrane transport	1.090094e-2
GO:0030217	T cell differentiation	1.105505e-2
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	1.113986e-2
GO:0015670	carbon dioxide transport	1.113986e-2
GO:0043366	beta selection	1.113986e-2
GO:2000727	positive regulation of cardiac muscle cell differentiation	1.119399e-2
GO:0030041	actin filament polymerization	1.119399e-2
GO:0032506	cytokinetic process	1.120862e-2
GO:0042311	vasodilation	1.132918e-2
GO:0002839	positive regulation of immune response to tumor cell	1.133633e-2
GO:0019400	alditol metabolic process	1.146308e-2
GO:0001523	retinoid metabolic process	1.146308e-2
GO:2000383	regulation of ectoderm development	1.159650e-2
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	1.159650e-2
GO:0007418	ventral midline development	1.159650e-2
GO:0016476	regulation of embryonic cell shape	1.159650e-2
GO:0015698	inorganic anion transport	1.163306e-2
GO:0008016	regulation of heart contraction	1.164461e-2
GO:0051099	positive regulation of binding	1.185594e-2
GO:0048519	negative regulation of biological process	1.196810e-2
GO:0046883	regulation of hormone secretion	1.204461e-2
GO:0048295	positive regulation of isotype switching to IgE isotypes	1.215177e-2
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	1.215177e-2
GO:0031953	negative regulation of protein autophosphorylation	1.215218e-2
GO:0050701	interleukin-1 secretion	1.222100e-2
GO:0045621	positive regulation of lymphocyte differentiation	1.225659e-2
GO:0034104	negative regulation of tissue remodeling	1.227356e-2
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	1.227356e-2
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	1.230172e-2
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	1.236509e-2
GO:0045668	negative regulation of osteoblast differentiation	1.237206e-2
GO:0045582	positive regulation of T cell differentiation	1.247832e-2
GO:0006417	regulation of translation	1.259469e-2
GO:0006081	cellular aldehyde metabolic process	1.261136e-2
GO:0042102	positive regulation of T cell proliferation	1.261452e-2
GO:0031342	negative regulation of cell killing	1.273850e-2
GO:0002251	organ or tissue specific immune response	1.290731e-2
GO:0046427	positive regulation of JAK-STAT cascade	1.297679e-2
GO:0090231	regulation of spindle checkpoint	1.302640e-2
GO:0009649	entrainment of circadian clock	1.302640e-2
GO:0002698	negative regulation of immune effector process	1.302828e-2
GO:0035802	adrenal cortex formation	1.305995e-2
GO:0019852	L-ascorbic acid metabolic process	1.306558e-2
GO:0070980	biphenyl catabolic process	1.313449e-2
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.326423e-2
GO:0046321	positive regulation of fatty acid oxidation	1.327734e-2
GO:2000725	regulation of cardiac muscle cell differentiation	1.328441e-2
GO:0032612	interleukin-1 production	1.337104e-2
GO:0051052	regulation of DNA metabolic process	1.344409e-2
GO:0016578	histone deubiquitination	1.344623e-2
GO:0097113	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering	1.344623e-2
GO:0001915	negative regulation of T cell mediated cytotoxicity	1.356504e-2
GO:0046328	regulation of JNK cascade	1.360682e-2
GO:0060968	regulation of gene silencing	1.380512e-2
GO:0042572	retinol metabolic process	1.380512e-2
GO:0032609	interferon-gamma production	1.400847e-2
GO:0014052	regulation of gamma-aminobutyric acid secretion	1.400847e-2
GO:0002831	regulation of response to biotic stimulus	1.413792e-2
GO:0065007	biological regulation	1.423149e-2
GO:0042325	regulation of phosphorylation	1.423937e-2
GO:0031622	positive regulation of fever generation	1.430452e-2
GO:0034435	cholesterol esterification	1.430452e-2
GO:0010824	regulation of centrosome duplication	1.430452e-2
GO:0007605	sensory perception of sound	1.441098e-2
GO:0046186	acetaldehyde biosynthetic process	1.442182e-2
GO:0006788	heme oxidation	1.442182e-2
GO:0042487	regulation of odontogenesis of dentine-containing tooth	1.459180e-2
GO:0006987	activation of signaling protein activity involved in unfolded protein response	1.463590e-2
GO:0045428	regulation of nitric oxide biosynthetic process	1.466034e-2
GO:0045921	positive regulation of exocytosis	1.471328e-2
GO:0046685	response to arsenic-containing substance	1.484475e-2
GO:0010224	response to UV-B	1.484475e-2
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	1.484475e-2
GO:0014850	response to muscle activity	1.484475e-2
GO:0043011	myeloid dendritic cell differentiation	1.484475e-2
GO:0002833	positive regulation of response to biotic stimulus	1.490563e-2
GO:0006208	pyrimidine base catabolic process	1.495442e-2
GO:0006098	pentose-phosphate shunt	1.502306e-2
GO:0009581	detection of external stimulus	1.510635e-2
GO:0006406	mRNA export from nucleus	1.511083e-2
GO:0090273	regulation of somatostatin secretion	1.520118e-2
GO:0045956	positive regulation of calcium ion-dependent exocytosis	1.537496e-2
GO:0006766	vitamin metabolic process	1.550329e-2
GO:0006909	phagocytosis	1.566552e-2
GO:0006621	protein retention in ER lumen	1.612501e-2
GO:0043306	positive regulation of mast cell degranulation	1.613707e-2
GO:0006266	DNA ligation	1.613707e-2
GO:0042404	thyroid hormone catabolic process	1.620654e-2
GO:0050885	neuromuscular process controlling balance	1.624120e-2
GO:0085020	protein K6-linked ubiquitination	1.632692e-2
GO:0071637	regulation of monocyte chemotactic protein-1 production	1.632692e-2
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1.632692e-2