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MCL coexpression mm9:1381

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Phase1 CAGE Peaks

 Short description
Mm9::chr16:43363152..43363186,+p3@Zbtb20
Mm9::chr16:43363190..43363242,+p2@Zbtb20
Mm9::chr17:47147360..47147379,-p3@Ubr2
Mm9::chr18:64648600..64648630,-p2@Fech
Mm9::chr18:64648631..64648636,-p4@Fech
Mm9::chr9:106378703..106378715,-p5@Parp3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004325ferrochelatase activity0.0118336711773407
GO:0009589detection of UV0.0118336711773407
GO:0007141male meiosis I0.0236634524010587
GO:0007140male meiosis0.0386743023199266
GO:0006783heme biosynthetic process0.0386743023199266
GO:0033014tetrapyrrole biosynthetic process0.0386743023199266
GO:0006779porphyrin biosynthetic process0.0386743023199266
GO:00515372 iron, 2 sulfur cluster binding0.0386743023199266
GO:0042168heme metabolic process0.0386743023199266
GO:0033013tetrapyrrole metabolic process0.0386743023199266
GO:0006778porphyrin metabolic process0.0386743023199266
GO:0009411response to UV0.0438634091509944
GO:0009583detection of light stimulus0.0438634091509944
GO:0046148pigment biosynthetic process0.0438634091509944
GO:0042440pigment metabolic process0.0474009416398943
GO:0046914transition metal ion binding0.0474009416398943
GO:0000151ubiquitin ligase complex0.0494137464595127
GO:0051536iron-sulfur cluster binding0.0494137464595127
GO:0019748secondary metabolic process0.0494137464595127
GO:0051540metal cluster binding0.0494137464595127
GO:0009582detection of abiotic stimulus0.0494137464595127



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
epithelial tube1.64e-1047
cardiovascular system4.88e-0823
circulatory system4.88e-0823


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.39154
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.304529
MA0017.10.387481
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.969171
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.486223
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.10.465302
MA0056.10
MA0057.10.149949
MA0058.10.436487
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.153907
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.111.8864
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.358337
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.11.51574
MA0101.10.458688
MA0103.10.398766
MA0105.10.199622
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.359483
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.11.96032
MA0140.10.625902
MA0141.10.419361
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.11.814
MA0146.12.42438
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.591842
MA0035.20.630778
MA0039.20.525037
MA0138.20.788113
MA0002.20.246463
MA0137.21.06926
MA0104.20.261255
MA0047.20.685741
MA0112.20.37938
MA0065.20.380324
MA0150.11.29346
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.480757
MA0155.10.414701
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.12.40387
MA0160.11.36931
MA0161.10
MA0162.10.70356
MA0163.10.664494
MA0164.10.658997
MA0080.20.393257
MA0018.20.669032
MA0099.20.781628
MA0079.22.41728
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10