DOID:0060083

Name:	immune system cancer
Namespace:	disease_ontology
Definition:	"An organ system cancer located_in the immune system that is characterized by uncontrolled cellular proliferation in organs of the immune system." [url:http://en.wikipedia.org/wiki/Immune_system]
Created by:	lschriml
Creation date:	2011-06-08T01:11:18Z

Ontology association<br>Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	DOID:0050686(organ system cancer)

Children

is a:	DOID:0060073 (lymphatic system cancer),DOID:2531 (hematologic cancer),DOID:3277 (thymus cancer)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples

Human (Homo sapiens)

• 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
• 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
• 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
• 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
• 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
• 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
• 10422-106C8 (Burkitt's lymphoma cell line:DAUDI)
• 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
• 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
• 10435-106E3 (Hodgkin's lymphoma cell line:HD-Mar2)

... further results Mouse (Mus musculus)

• 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
• 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
• 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
• 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
• 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
• 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
• 10422-106C8 (Burkitt's lymphoma cell line:DAUDI)
• 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
• 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
• 10435-106E3 (Hodgkin's lymphoma cell line:HD-Mar2)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:0060083 (immune system cancer), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
7.91e-91	FFCP PHASE2:Hg19::chr6:135513595..135513617,+	p4@MYB
7.91e-91	FFCP PHASE1:Hg19::chr6:135513595..135513617,+	p4@MYB
1.58e-86	FFCP PHASE2:Mm9::chr10:76688454..76688462,+	p@chr10:76688454..76688462, +
1.58e-86	FFCP PHASE2:Mm9::chr11:102331415..102331424,-	p9@Itga2b
1.58e-86	FFCP PHASE2:Mm9::chr10:76688464..76688474,+	p@chr10:76688464..76688474, +
1.58e-86	FFCP PHASE1:Mm9::chr11:102331415..102331424,-	p9@Itga2b
1.58e-86	FFCP PHASE1:Mm9::chr10:76688454..76688462,+	p@chr10:76688454..76688462, +
1.58e-86	FFCP PHASE1:Mm9::chr10:76688464..76688474,+	p@chr10:76688464..76688474, +
3.61e-86	FFCP PHASE1:Hg19::chr12:58329793..58329806,-	p2@ENST00000547492
3.61e-86	FFCP PHASE2:Hg19::chr12:58329793..58329806,-	p2@ENST00000547492
1.2e-85	FFCP PHASE2:Hg19::chr12:58329776..58329791,-	p3@ENST00000547492
1.2e-85	FFCP PHASE1:Hg19::chr12:58329776..58329791,-	p3@ENST00000547492
4.4e-85	FFCP PHASE2:Hg19::chr6:135533394..135533403,+	p@chr6:135533394..135533403, +
4.4e-85	FFCP PHASE1:Hg19::chr6:135533394..135533403,+	p@chr6:135533394..135533403, +
2.22e-77	FFCP PHASE2:Hg19::chr6:135502472..135502489,+	p3@MYB
2.22e-77	FFCP PHASE1:Hg19::chr6:135502472..135502489,+	p3@MYB
9.4e-76	FFCP PHASE2:Hg19::chr6:68598272..68598298,-	p@chr6:68598272..68598298, -
9.4e-76	FFCP PHASE1:Hg19::chr6:68598272..68598298,-	p@chr6:68598272..68598298, -
2.03e-75	FFCP PHASE1:Hg19::chr16:29674970..29675007,+	p4@SPN
2.03e-75	FFCP PHASE2:Hg19::chr16:29674970..29675007,+	p4@SPN
7.69e-75	FFCP PHASE2:Hg19::chr12:58329762..58329773,-	p5@ENST00000547492
7.69e-75	FFCP PHASE1:Hg19::chr12:58329762..58329773,-	p5@ENST00000547492
1.51e-73	FFCP PHASE1:Hg19::chr1:202129105..202129140,-	p2@PTPN7
1.51e-73	FFCP PHASE2:Hg19::chr1:202129105..202129140,-	p2@PTPN7
1.25e-71	FFCP PHASE1:Hg19::chr6:68592986..68593000,-	p@chr6:68592986..68593000, -
1.25e-71	FFCP PHASE2:Hg19::chr6:68592986..68593000,-	p@chr6:68592986..68593000, -
1.49e-71	FFCP PHASE2:Hg19::chr6:68598314..68598325,-	p@chr6:68598314..68598325, -
1.49e-71	FFCP PHASE1:Hg19::chr6:68598314..68598325,-	p@chr6:68598314..68598325, -
7.94e-68	FFCP PHASE2:Hg19::chr6:68593536..68593560,-	p@chr6:68593536..68593560, -
7.94e-68	FFCP PHASE2:Hg19::chr6:68596384..68596400,-	p@chr6:68596384..68596400, -
7.94e-68	FFCP PHASE1:Hg19::chr6:68593536..68593560,-	p@chr6:68593536..68593560, -
7.94e-68	FFCP PHASE1:Hg19::chr6:68596384..68596400,-	p@chr6:68596384..68596400, -
7.94e-68	FFCP PHASE2:Hg19::chr6:68591611..68591627,-	p@chr6:68591611..68591627, -
7.94e-68	FFCP PHASE1:Hg19::chr6:68591611..68591627,-	p@chr6:68591611..68591627, -
3.59e-67	FFCP PHASE2:Hg19::chr16:29675010..29675041,+	p5@SPN
3.59e-67	FFCP PHASE1:Hg19::chr16:29675010..29675041,+	p5@SPN
1.24e-65	FFCP PHASE2:Hg19::chr6:135516978..135516993,+	p7@MYB
1.24e-65	FFCP PHASE1:Hg19::chr6:135516978..135516993,+	p7@MYB
1.33e-65	FFCP PHASE1:Mm9::chrX:160480258..160480272,-	p@chrX:160480258..160480272, -
1.33e-65	FFCP PHASE2:Mm9::chr2:156853485..156853494,-	p13@9830001H06Rik
1.33e-65	FFCP PHASE1:Mm9::chr19:8798483..8798487,+	p1@ENSMUST00000082787
1.33e-65	FFCP PHASE2:Mm9::chrX:160480258..160480272,-	p@chrX:160480258..160480272, -
1.33e-65	FFCP PHASE1:Mm9::chr2:156853485..156853494,-	p13@9830001H06Rik
1.33e-65	FFCP PHASE2:Mm9::chr19:8798483..8798487,+	p1@ENSMUST00000082787
1.56e-64	FFCP PHASE2:Hg19::chr6:68598245..68598268,-	p@chr6:68598245..68598268, -
1.56e-64	FFCP PHASE1:Hg19::chr6:68598245..68598268,-	p@chr6:68598245..68598268, -
3.76e-64	FFCP PHASE1:Hg19::chr6:68598507..68598519,-	p@chr6:68598507..68598519, -
3.76e-64	FFCP PHASE2:Hg19::chr6:68598507..68598519,-	p@chr6:68598507..68598519, -
4.16e-64	FFCP PHASE2:Hg19::chr6:68598587..68598598,-	p@chr6:68598587..68598598, -
4.16e-64	FFCP PHASE2:Hg19::chr6:68595369..68595417,-	p@chr6:68595369..68595417, -
4.16e-64	FFCP PHASE1:Hg19::chr6:68598587..68598598,-	p@chr6:68598587..68598598, -
4.16e-64	FFCP PHASE1:Hg19::chr6:68595369..68595417,-	p@chr6:68595369..68595417, -
2.54e-62	FFCP PHASE1:Hg19::chr11:17297848..17297868,+	p9@NUCB2
2.54e-62	FFCP PHASE2:Hg19::chr11:17297848..17297868,+	p9@NUCB2
1.55e-60	FFCP PHASE2:Hg19::chr6:135526382..135526388,+	p@chr6:135526382..135526388, +
1.55e-60	FFCP PHASE1:Hg19::chr6:135526382..135526388,+	p@chr6:135526382..135526388, +
2.15e-60	FFCP PHASE1:Hg19::chr6:68597599..68597612,-	p@chr6:68597599..68597612, -
2.15e-60	FFCP PHASE1:Hg19::chr6:68596698..68596715,-	p@chr6:68596698..68596715, -
2.15e-60	FFCP PHASE2:Hg19::chr6:68598534..68598555,-	p@chr6:68598534..68598555, -
2.15e-60	FFCP PHASE1:Hg19::chr6:68598534..68598555,-	p@chr6:68598534..68598555, -
2.15e-60	FFCP PHASE2:Hg19::chr6:68596826..68596859,-	p@chr6:68596826..68596859, -
2.15e-60	FFCP PHASE2:Hg19::chr6:68592948..68592958,-	p@chr6:68592948..68592958, -
2.15e-60	FFCP PHASE1:Hg19::chr6:68596826..68596859,-	p@chr6:68596826..68596859, -
2.15e-60	FFCP PHASE1:Hg19::chr6:68592948..68592958,-	p@chr6:68592948..68592958, -
2.15e-60	FFCP PHASE2:Hg19::chr6:68597599..68597612,-	p@chr6:68597599..68597612, -
2.15e-60	FFCP PHASE2:Hg19::chr6:68596698..68596715,-	p@chr6:68596698..68596715, -
2.4e-60	FFCP PHASE1:Hg19::chr19:695494..695510,-	p3@PRSS57
2.4e-60	FFCP PHASE2:Hg19::chr19:695494..695510,-	p3@PRSS57
5.98e-60	FFCP PHASE2:Hg19::chr6:68599042..68599067,-	p1@uc003pes.1, p1@uc003pet.1
5.98e-60	FFCP PHASE1:Hg19::chr6:68599042..68599067,-	p1@uc003pes.1, p1@uc003pet.1
1.21e-59	FFCP PHASE1:Hg19::chr11:33913475..33913549,-	p5@LMO2
1.21e-59	FFCP PHASE2:Hg19::chr11:33913475..33913549,-	p5@LMO2
1.58e-59	FFCP PHASE2:Hg19::chr6:135501708..135501716,+	p@chr6:135501708..135501716, +
1.58e-59	FFCP PHASE1:Hg19::chr6:135501708..135501716,+	p@chr6:135501708..135501716, +
1.6e-59	FFCP PHASE2:Hg19::chrX:65146038..65146063,-	p@chrX:65146038..65146063, -
1.6e-59	FFCP PHASE1:Hg19::chrX:65146038..65146063,-	p@chrX:65146038..65146063, -
2.35e-59	FFCP PHASE1:Hg19::chr8:130560794..130560810,-	p@chr8:130560794..130560810, -
2.35e-59	FFCP PHASE2:Hg19::chr8:130560794..130560810,-	p@chr8:130560794..130560810, -
2.1e-58	FFCP PHASE2:Hg19::chr8:130560752..130560768,-	p@chr8:130560752..130560768, -
2.1e-58	FFCP PHASE1:Hg19::chr8:130560752..130560768,-	p@chr8:130560752..130560768, -
3.28e-58	FFCP PHASE1:Mm9::chr11:104171122..104171127,+	p@chr11:104171122..104171127, +
3.28e-58	FFCP PHASE2:Mm9::chr11:104171122..104171127,+	p@chr11:104171122..104171127, +
9.68e-58	FFCP PHASE1:Hg19::chr6:68598984..68598997,-	p2@uc003pes.1, p2@uc003pet.1
9.68e-58	FFCP PHASE2:Hg19::chr6:68598984..68598997,-	p2@uc003pes.1, p2@uc003pet.1
9.63e-57	FFCP PHASE2:Hg19::chr6:68593520..68593534,-	p@chr6:68593520..68593534, -
9.63e-57	FFCP PHASE1:Hg19::chr6:68593520..68593534,-	p@chr6:68593520..68593534, -
1.09e-56	FFCP PHASE2:Hg19::chr6:68596343..68596355,-	p@chr6:68596343..68596355, -
1.09e-56	FFCP PHASE2:Hg19::chr6:68596783..68596797,-	p@chr6:68596783..68596797, -
1.09e-56	FFCP PHASE1:Hg19::chr6:68596343..68596355,-	p@chr6:68596343..68596355, -
1.09e-56	FFCP PHASE1:Hg19::chr6:68596783..68596797,-	p@chr6:68596783..68596797, -
4.1e-55	FFCP PHASE2:Hg19::chr6:68593206..68593218,-	p@chr6:68593206..68593218, -
4.1e-55	FFCP PHASE1:Hg19::chr6:68593206..68593218,-	p@chr6:68593206..68593218, -
1.62e-54	FFCP PHASE1:Hg19::chr12:58329689..58329704,-	p4@ENST00000547492
1.62e-54	FFCP PHASE2:Hg19::chr12:58329689..58329704,-	p4@ENST00000547492
2.35e-54	FFCP PHASE2:Hg19::chr3:53231298..53231310,+	p@chr3:53231298..53231310, +
2.35e-54	FFCP PHASE1:Hg19::chr3:53231298..53231310,+	p@chr3:53231298..53231310, +
3.68e-54	FFCP PHASE2:Hg19::chr3:18020982..18021001,+	p@chr3:18020982..18021001, +
3.68e-54	FFCP PHASE1:Hg19::chr3:18020982..18021001,+	p@chr3:18020982..18021001, +
1.18e-53	FFCP PHASE1:Hg19::chr11:17297872..17297908,+	p7@NUCB2
1.18e-53	FFCP PHASE2:Hg19::chr11:17297872..17297908,+	p7@NUCB2

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